Explanipedia

Perinatal Prognostic Factors of Recurrence or Functional Sequelae in Neonatal Sacrococcygeal Teratoma, and Implications for Prenatal Counselling: A Multicenter Retrospective Study Open

Nicolas Vinit, Arnaud Bonnard, Sabine Irtan, Virginie Fouquet, Y. Ville , et al. · 2025

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Rationale for the use of fetal ventriculosubgaleal shunts for the treatment of aqueduct stenosis Open

Shohra Qaderi, Weston T. Northam, Ramen H. Chmait, Mark D. Krieger, Y. Ville , et al. · 2025

Fetal hydrocephalus causes irreversible neural injury in utero , yet no prenatal therapy currently exists. Postnatal treatments such as ventriculoperitoneal shunts and endoscopic third ventriculostomy with choroid plexus cauterization cann…

Prenatal diagnosis and postnatal management of perinatal thoracoabdominopelvic tumors: multicenter experience Open

C. Khawand, Daniel Orbach, D. Berrebi, Sophie Branchereau, Charlotte Mussini , et al. · 2025

Objectives The primary objective was to assess the accuracy of prenatal examination in detecting and characterizing perinatal solid tumors of the thoracoabdominopelvic region. Secondary objectives were to describe the epidemiology, clinica…

Offline ultrasound– MRI fusion imaging for assessment of normal fetal brain development Open

C. Codaccioni, Chloé Arthuis, B. Deloison, J.‐P. Bault, Claude R. Henry , et al. · 2025

Objectives Offline fusion imaging refers to a posteriori merging of two datasets, from the same or from different imaging modalities. The objectives were to assess the feasibility of a standardized manual method for the offline fusion of t…

Single fetal demise in twin anemia–polycythemia sequence: perinatal outcome of surviving cotwin Open

M J A van de Sande, E. Lopriore, Mariano Lanna, Y. Ville, Liesbeth Lewi , et al. · 2025

Objective To evaluate the perinatal outcome after spontaneous single intrauterine fetal demise (IUFD) in monochorionic twin pregnancies with twin anemia–polycythemia sequence (TAPS). Methods This was a retrospective study of all monochorio…

Metagenomic analysis of NIPT raw data suggests high negative predictive value for congenital cytomegalovirus infection screening Open

Nicolas Bourgon, Ismaël Padioleau, Julie Guibon, Jacques Fourgeaud, Alban Lermine , et al. · 2025

International audience

COG6‐related prenatal phenotype (CDG2L): Clinico‐pathological report and review of the literature Open

Sarah Guterman, Agnese Feresin, Lucile Boutaud, Clémence Jacquin, Stanislas Lyonnet , et al. · 2025

Background CDG2L (MIM#614576) is an autosomal recessive multisystemic disorder due to variants in COG6 gene. Postnatal phenotypes are now well described, while prenatal presentations remain poorly investigated. Only 8 of the 28 published p…

ISUOG Practice Guidelines (updated): role of ultrasound in twin pregnancy Open

A. Khalil, Alexandros Sotiriadis, Ahmet Baschat, A. Bhide, E. Gratacós , et al. · 2025

Growth velocity of fetal sacrococcygeal teratoma as predictor of perinatal morbidity and mortality: multicenter study Open

Nicolas Vinit, Alexandra Benachi, Jonathan Rosenblatt, Jean‐Marie Jouannic, Véronique Rousseau , et al. · 2024

Objective To identify prenatal predictors of poor perinatal outcome in fetuses with isolated sacrococcygeal teratoma (SCT). Methods This was a retrospective study of fetuses with isolated (non‐syndromic) SCT managed at one of five pediatri…

Corrigendum to “Consensus recommendation for prenatal, neonatal and postnatal management of congenital cytomegalovirus infection from the European congenital infection initiative (ECCI)” [The Lancet Regional Health – Europe 40 (2024) 100892] Open

Marianne Leruez‐Ville, Christos Chatzakis, Daniele Lilleri, Daniel Blázquez‐Gamero, Ana Alarcón , et al. · 2024

Consensus recommendation for prenatal, neonatal and postnatal management of congenital cytomegalovirus infection from the European congenital infection initiative (ECCI) Open

Marianne Leruez‐Ville, Christos Chatzakis, Daniele Lilleri, Daniel Blázquez‐Gamero, Ana Alarcón , et al. · 2024

OP02.06: Do we need prenatal MRI in COVID‐19 pregnancies? Open

Patric Kienast, Daniela Prayer, Christina Lindan, Y. Ville, Julia Binder , et al. · 2023

There is histological evidence of COVID-19 affecting the vascular bed of the placenta. However, detrimental effects on the fetus have sparsely been documented. The aim of this study was to evaluate whether COVID-19-associated placental imp…

OC01.01: Performance of an AI algorithm for quality control of routine fetal ultrasound Open

J. Stirnemann, R. Besson, Vianney Debavelaere, Frédéric Logé, C. Amabile , et al. · 2023

17,169 screening fetal US images, performed in all trimesters (T1, T2, T3), were collected from 7 North-American and European centres. The performance (sensitivity and specificity) of the software was assessed by comparing the algorithm's …

EP21.28: Prenatal diagnosis of Primrose syndrome Open

Wael Abdallah, Thibaud Quibel, Sophie Brisset, Rodolphe Dard, Emmanuel Spaggiari , et al. · 2023

Results:We collected 5 cases of aneuploidies apart from Trisomy 21: 2 cases of Trisomy 18, one case of Trisomy 9 as well as one case of Klinefelter syndrome and one case of Turner syndrome.The diagnosis was confirmed in the 2nd trimester i…

EP02.43: Performance of an AI software for standard heart planes extraction from heart clips: study proposal Open

Angela C. Ranzini, Yinka Oyelese, K. R. Faulk, Michael B. Flinn, R. Besson , et al. · 2023

Extracting the best image from a clip in clinical routine fetal ultrasound is a complex task that requires expertise, dedicated time and appropriate training. The objective will be to assess the performance of an artificial intelligence (A…

OP04.01: Fetal diffusion tensor imaging in case of “short” corpus callosum Open

R. Corroënne, D. Grévent, Houman Mahallati, A. Millischer, Gérome C. Gauchard , et al. · 2023

To compare the diffusion tensor imaging (DTI) metrics in the corpus callous (CC) in fetuses with “short” CC (SCC) with normal CC and between SCC with and without Probst bundles (PB). Retrospective study of fetuses with an apparently isolat…

EP25.25: Physicians' perceptions of the daily use of a handheld ultrasound device in the labour room Open

R. Corroënne, Marion Chesnais, C. Khawand, Isabelle Attali, Marianne France , et al. · 2023

Conclusions: Cortisol level, cervical length, PCA display poor sensitivity and

OP06.09: Validation of optical positioning ultrasound simulator as an autonomous tool for assessment of ultrasound operator competence in obstetrics Open

R. Corroënne, M. Jacquier, J. Stirnemann, Laurent Salomon, Y. Ville , et al. · 2023

To validate the use of an optical positioning ultrasound simulation (OPUS) system for obstetrical ultrasound (US) skills' assessment compared with the conventional examination on volunteer pregnant women. Trainees taking the 2022 practical…

Severe and fatal neonatal infections linked to a new variant of echovirus 11, France, July 2022 to April 2023 Open

Mathilde Grapin, Audrey Mirand, Didier Pinquier, A. Basset, Matthieu Bendavid , et al. · 2023

We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3–5 days-old and had severe sepsis and liver failure. This new variant, detected in France sinc…

Development and clinical validation of real‐time artificial intelligence diagnostic companion for fetal ultrasound examination Open

J. Stirnemann, R. Besson, Emmanuel Spaggiari, S Rojo, Frédéric Logé , et al. · 2023

Objective Prenatal diagnosis of a rare disease on ultrasound relies on a physician's ability to remember an intractable amount of knowledge. We developed a real‐time decision support system (DSS) that suggests, at each step of the examinat…

Corpus callosal reference ranges: systematic review of methodology of biometric chart construction and measurements obtained Open

R. Corroënne, D. Grévent, Gregor Kasprian, J. Stirnemann, Y. Ville , et al. · 2023

Objective Adequate reference ranges of size of the corpus callosum (CC) are necessary to improve characterization of CC abnormalities and parental counseling. The objective of this study was to evaluate the methodology used in studies deve…

Prise en charge prénatale des obstacles sous-vésicaux Open

Nicolas Vinit, Y. Ville, Thomas Blanc · 2023

Les résultats du traitement prénatal des obstacles sous-vésicaux sont souvent mitigés en termes de bénéfices sur la fonction rénale. Devant le diagnostic prénatal de mégavessie fœtale persistante, aucun signe échographique ne permet actuel…

Maternal and perinatal outcomes following pre-Delta, Delta, and Omicron SARS-CoV-2 variants infection among unvaccinated pregnant women in France and Switzerland: a prospective cohort study using the COVI-PREG registry Open

Guillaume Favre, Émeline Maisonneuve, Léo Pomar, Charlotte Daire, C. Poncelet , et al. · 2023

Neonatal and long‐term outcomes of infants with congenital cytomegalovirus infection and negative amniocentesis: systematic review and meta‐analysis Open

Christos Chatzakis, Alexandros Sotiriadis, Konstantinos Dinas, Y. Ville · 2022

Objective Cytomegalovirus (CMV) DNA is detectable in the amniotic fluid collected by amniocentesis in cases in which the fetus has been infected. However, cases of congenital neonatal CMV infection with a negative amniocentesis result have…

Neonatal Hemodynamic Characteristics of the Recipient Twin of Twin-To-Twin Transfusion Syndrome Not Treated with Fetoscopic Laser Surgery Open

Edouard Chambon, Taymme Hachem, Elodie Salvador, Virginie Rigourd, Claire Bellanger , et al. · 2022

Background: This paper’s intent is to describe the neonatal hemodynamic characteristics of recipient twins of monochorionic pregnancies complicated with twin-to-twin transfusion syndrome (TTTS), born without prenatal fetoscopic selective l…

Cancer-associated Mutations in Congenital Pulmonary Malformations: A Prospective Cohort Open

Simon Garinet, Makan Rahshenas, Louise Galmiche, Olivier Abbo, Arnaud Bonnard , et al. · 2022

Cytokine Profiling of Amniotic Fluid from Congenital Cytomegalovirus Infection Open

Nicolas Bourgon, Wendy Fitzgerald, Hugues Aschard, Jean‐François Magny, Tiffany Guilleminot , et al. · 2022

Background: Congenital cytomegalovirus (cCMV) infection is frequent and potentially severe. The immunobiology of cCMV infection is poorly understood, involving cytokines that could be carried within or on the surface of extracellular vesic…

Clinical Value of Serial Quantitative Analysis of Cytomegalovirus DNA in Blood and Saliva Over the First 24 Months of Life in Congenital Infection: The French Cymepedia Cohort Open

Jacques Fourgeaud, Jean‐François Magny, Sophie Couderc, Patricia Garcia, Anne-Marie Maillotte , et al. · 2022

Third trimester placentitis: an underreported complication of SARS-CoV-2 infection Open

Joanna Sichitiu, Nicolas Bourgon, Tiffany Guilleminot, Bettina Bessières, Marianne Leruez‐Ville , et al. · 2022

Fetoscopic Laser Ablation for the Selective Fetal Reduction in Twin-Twin Transfusion Syndrome Stage II–IV: The Experience of a New Fetal Medicine Center Open

Anh Duy Nguyen, Hung S. Ho, Nguyen Thi Sim, Nguyen Thi Thu Ha, Duc lam Nguyen , et al. · 2022

Our study showed that fetoscopic laser ablation of selected fetal reduction surgery for treatment of special conditions of TTTS had no complications of operation, high neonatal survival result (90.48%), no short-term neurological complicat…

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