Chen Chun-ya
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View article: Anisomeles indica enriched with ovatodiolide protects against aspirin-induced gastric ulcers through gut microbiota modulation
Anisomeles indica enriched with ovatodiolide protects against aspirin-induced gastric ulcers through gut microbiota modulation Open
This study provides insights into the mechanisms by which A. indica alleviates gastric ulcers, highlighting its ability to modulate gut microbiota and enhance mucosal protection.
View article: RAGE participates in the intracellular transport of Campylobacter jejuni cytolethal distending toxin
RAGE participates in the intracellular transport of Campylobacter jejuni cytolethal distending toxin Open
Our results demonstrate that RAGE is important for CDT trafficking in the cells. These findings expand our understanding of important issues related to host cell intoxication by C. jejuni CDT.
View article: Raloxifene Protects Cisplatin-Induced Renal Injury in Mice via Inhibiting Oxidative Stress
Raloxifene Protects Cisplatin-Induced Renal Injury in Mice via Inhibiting Oxidative Stress Open
Raloxifene protected against cisplatin-induced nephrotoxicity by activating the antioxidant system, along with alleviating liver damage. It should be considered as a potential adjuvant in cisplatin-based chemotherapeutic protocols.
View article: Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro Open
Our study suggests that normal basal epithelial cells might stimulate the migration and invasion of RM-1 by TGF-β1/STAT3 axis which could be suppressed by inhibitor of TGF-β receptor and inhibitor of p-STAT3. So, basal epithelial cells mig…
View article: <i>Helicobacter pylori</i> cholesterol-α-glucosyltransferase manipulates cholesterol for bacterial adherence to gastric epithelial cells
<i>Helicobacter pylori</i> cholesterol-α-glucosyltransferase manipulates cholesterol for bacterial adherence to gastric epithelial cells Open
Helicobacter pylori infection is associated with several gastrointestinal diseases, including gastritis, peptic ulcers, and gastric cancer. Infection of cells with H. pylori is dependent on lipid rafts, which are cholesterol-…
View article: Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation
Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation Open
Helicobacter pylori colonizes human gastric epithelial cells and contributes to the development of several gastrointestinal disorders. Interleukin (IL)-33 is involved in various immune responses, with reported proinflammatory and anti-infl…
View article: Aggregate analysis based on TCGA: TTN missense mutation correlates with favorable prognosis in lung squamous cell carcinoma
Aggregate analysis based on TCGA: TTN missense mutation correlates with favorable prognosis in lung squamous cell carcinoma Open