Yibin Wang
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View article: Intratumoral Heterogeneity of MAGED4 Expression in Oral Squamous Cell Carcinoma: Epigenetic Mechanisms and Therapeutic Implications
Intratumoral Heterogeneity of MAGED4 Expression in Oral Squamous Cell Carcinoma: Epigenetic Mechanisms and Therapeutic Implications Open
Intratumoral heterogeneity poses significant challenges to the efficacy of cancer immunotherapy. Melanoma-associated antigen D4 (MAGED4) has been proposed as a potential immunotherapeutic target in oral squamous cell carcinoma (OSCC). This…
View article: Quantitative Assessment of Peritumoral Stiffness Using Shell Elastography Enhances the Differentiation of Hepatocellular Carcinoma From Metastatic Liver Carcinoma
Quantitative Assessment of Peritumoral Stiffness Using Shell Elastography Enhances the Differentiation of Hepatocellular Carcinoma From Metastatic Liver Carcinoma Open
Objectives To evaluate the discriminatory potential of peritumoral tissue stiffness, as quantified by 2‐dimensional shear wave elastography, for distinguishing between hepatocellular carcinoma (HCC) and metastatic liver carcinoma (MLC). Me…
View article: LiteraryTaste: A Preference Dataset for Creative Writing Personalization
LiteraryTaste: A Preference Dataset for Creative Writing Personalization Open
People have different creative writing preferences, and large language models (LLMs) for these tasks can benefit from adapting to each user's preferences. However, these models are often trained over a dataset that considers varying person…
View article: Dual Transcriptomic Analysis Unraveling the Immune Landscape and Host-Pathogen Interactions during Mycobacterium tuberculosis Infection
Dual Transcriptomic Analysis Unraveling the Immune Landscape and Host-Pathogen Interactions during Mycobacterium tuberculosis Infection Open
View article: Genetic variants in the homologous recombination pathway as common risk for premature ovarian insufficiency and ovarian cancer
Genetic variants in the homologous recombination pathway as common risk for premature ovarian insufficiency and ovarian cancer Open
View article: An Information Criterion Approach for Assessing Agreement When Comparing Two Methods of Measurement
An Information Criterion Approach for Assessing Agreement When Comparing Two Methods of Measurement Open
In laboratory and clinical sciences, it is a common enough challenge to compare two methods of measurement on the same set of samples or closely related samples with the goal of assessing agreement. Current regulatory guidance cites the Bl…
View article: Feasibility of magnetic resonance imaging compilation (MAGIC) for evaluating the depth of myometrial invasion and predicting the pathological subtypes of endometrial cancer: A comparison with high resolution T2WI and DWI
Feasibility of magnetic resonance imaging compilation (MAGIC) for evaluating the depth of myometrial invasion and predicting the pathological subtypes of endometrial cancer: A comparison with high resolution T2WI and DWI Open
Purpose To investigate the feasibility of MAGiC (sy-T2WI; T1, T2 and PD maps) for evaluating the depth of myometrial invasion (DMI) and predicting the pathological subtypes of endometrial cancer (EC) in comparison to hr-T2WI and DWI. Metho…
View article: Efficacy and Safety of Ca2+ Channel α2δ Ligands for the Treatment of Diabetic Peripheral Neuropathic Pain: A Systematic Review and Network Meta-analysis
Efficacy and Safety of Ca2+ Channel α2δ Ligands for the Treatment of Diabetic Peripheral Neuropathic Pain: A Systematic Review and Network Meta-analysis Open
View article: Health education based on precede-proceed model in eradication evaluation of Helicobacter pylori infection: a retrospective cohort study
Health education based on precede-proceed model in eradication evaluation of Helicobacter pylori infection: a retrospective cohort study Open
View article: Material hardship, not household income, predicts impaired punishment learning: a computational reinforcement learning perspective
Material hardship, not household income, predicts impaired punishment learning: a computational reinforcement learning perspective Open
Introduction Socioeconomic disadvantage has been linked to neurocognitive alterations in reward and loss processing, which may contribute to adverse psychological outcomes. However, the mechanisms through which it influences reinforcement …
View article: Clinical manifestations and outcomes of EBV-related secondary hemophagocytic lymphohistiocytosis
Clinical manifestations and outcomes of EBV-related secondary hemophagocytic lymphohistiocytosis Open
In summary, our study firstly reported the clinical manifestations and outcomes of EBV-related sHLH following allo-HSCT in the largest cohort at present.
View article: Petrogenesis of the Chamuhan Intrusion in the Southern Great Xing’an Range: Constraints from Zircon U-Pb Dating and Petrogeochemistry
Petrogenesis of the Chamuhan Intrusion in the Southern Great Xing’an Range: Constraints from Zircon U-Pb Dating and Petrogeochemistry Open
The Southern Great Xing’an Range (SGXR), an important W–Sn polymetallic metallogenic belt in northern China, hosts multiphase magmatism and has witnessed recent discoveries of multiple tungsten–tin polymetallic deposits. The W–Sn mineraliz…
View article: Federated Risk Discrimination with Siamese Networks for Financial Transaction Anomaly Detection
Federated Risk Discrimination with Siamese Networks for Financial Transaction Anomaly Detection Open
This paper proposes a deep risk discrimination framework that integrates a Siamese network structure with a federated optimization mechanism to address challenges in financial transaction environments, including multi-source heterogeneity,…
View article: Federated Risk Discrimination with Siamese Networks for Financial Transaction Anomaly Detection
Federated Risk Discrimination with Siamese Networks for Financial Transaction Anomaly Detection Open
This paper proposes a deep risk discrimination framework that integrates a Siamese network structure with a federated optimization mechanism to address challenges in financial transaction environments, including multi-source heterogeneity,…
View article: Composition of carotid plaques differs between Chinese and US patients: a histology study
Composition of carotid plaques differs between Chinese and US patients: a histology study Open
Background The clinical manifestations of cerebrovascular disease are known to differ between the Chinese and United States (US) populations as do the plaque features on imaging. Objectives The aim of this study was to investigate and comp…
View article: Comparative clinical outcomes of full-endoscopic posterior lumbar interbody fusion, biportal endoscopic posterior lumbar interbody fusion, and conventional posterior lumbar interbody fusion in the treatment of lumbar degenerative diseases
Comparative clinical outcomes of full-endoscopic posterior lumbar interbody fusion, biportal endoscopic posterior lumbar interbody fusion, and conventional posterior lumbar interbody fusion in the treatment of lumbar degenerative diseases Open
Objective This study aimed to evaluate and compare the clinical efficacy of three surgical procedures for lumbar degenerative disease (LDD): full-endoscopic posterior lumbar interbody fusion (Endo-PLIF), biportal endoscopic lumbar interbod…
View article: Lumina-DiMOO: An Omni Diffusion Large Language Model for Multi-Modal Generation and Understanding
Lumina-DiMOO: An Omni Diffusion Large Language Model for Multi-Modal Generation and Understanding Open
We introduce Lumina-DiMOO, an open-source foundational model for seamless multi-modal generation and understanding. Lumina-DiMOO sets itself apart from prior unified models by utilizing a fully discrete diffusion modeling to handle inputs …
View article: Transgene-Induced Chromosomal Rearrangement With Aberrant Human Vascular Endothelial Growth Factor at the Optic Fissure Leads to Uveal Coloboma in Mice
Transgene-Induced Chromosomal Rearrangement With Aberrant Human Vascular Endothelial Growth Factor at the Optic Fissure Leads to Uveal Coloboma in Mice Open
RICO represents a useful model for studying the pathogenesis of human coloboma.
View article: P. Gingivalils Induces Endothelial Dysfunction By mPTP Via Mitochondrial Fission
P. Gingivalils Induces Endothelial Dysfunction By mPTP Via Mitochondrial Fission Open
Aim or purpose: To explore the important role of Drp1-VDAC1-HK2 axis in regulating mitochondrial permeability transition pore (mPTP) opening in Porphyromonas gingivalis (P. gingivalis)-induced endothelial dysfunction. Materials and methods…
View article: Application of tubeless anesthesia for enhanced recovery after thoracoscopic wedge resection of the lung: a randomized trial
Application of tubeless anesthesia for enhanced recovery after thoracoscopic wedge resection of the lung: a randomized trial Open
Chinese Clinical Trial Registry ChiCTR2300073484.
View article: Z-DNA: Critical Scaffold And Trigger In Peri-Implantitis Pathogenesis
Z-DNA: Critical Scaffold And Trigger In Peri-Implantitis Pathogenesis Open
Aim or purpose: This investigation aims to characterize the previously unexplored contribution of Z-DNA conformations to peri-implantitis biofilm architecture, virulence mechanisms, and host inflammatory responses, thereby identifying nove…
View article: Oncogenic Role and Drug Resistance Effect of <scp>CCDC6</scp> in <scp>iCCA</scp>: Potential Strategies for Targeted Intervention
Oncogenic Role and Drug Resistance Effect of <span>CCDC6</span> in <span>iCCA</span>: Potential Strategies for Targeted Intervention Open
Intrahepatic cholangiocellular carcinoma (iCCA) is a digestive neoplasm with a very poor prognosis. This study examined the role of CCDC6 in the progression of iCCA and gemcitabine resistance through bioinformatics analysis and functional …
View article: Lung protective ventilation alleviates intracerebral hemorrhage-induced secondary brain and lung injury in mice via the Nrf2/HO‑1 pathway
Lung protective ventilation alleviates intracerebral hemorrhage-induced secondary brain and lung injury in mice via the Nrf2/HO‑1 pathway Open
Significant lung injury was evident on the 5th day after ICH. LPV alleviated neuronal damage, improved neurobehavioral outcomes, and reduced IL-6, IL-1β, and TNF-α in lung, blood, and brain. LPV activated the Nrf2/HO-1 pathway, decreasing …
View article: Research on the Countermeasures of Arduino Smart Warehouse Logistics Trolley in Warehouse Logistics
Research on the Countermeasures of Arduino Smart Warehouse Logistics Trolley in Warehouse Logistics Open
With the rapid development of e-commerce and logistics industries, the efficiency of warehouse logistics systems has become a key factor in corporate competition. This article focuses on the research of an intelligent warehouse logistics v…
View article: Glial fibrillary acidic protein autoimmunity in reversible splenial lesion syndrome: diagnostic and therapeutic implications
Glial fibrillary acidic protein autoimmunity in reversible splenial lesion syndrome: diagnostic and therapeutic implications Open
Autoimmune GFAP astrocytopathy (GFAP-A) is a neuroinflammatory condition that often involves the brain, meninges, and spinal cord. Its characteristic MRI finding consists of linear or radial perivascular enhancement adjacent to the ventric…
View article: Immunological Insights into the PI3K-Akt Pathway in Osteoporosis and Periodontitis: A Proteomic and Metabolomic Approach
Immunological Insights into the PI3K-Akt Pathway in Osteoporosis and Periodontitis: A Proteomic and Metabolomic Approach Open
The Article Abstract is not available.
View article: Effect of remote ischemic postconditioning on hepatic ischemia–reperfusion injury in patients undergoing laparoscopic hepatectomy: a randomized double-blinded controlled trial
Effect of remote ischemic postconditioning on hepatic ischemia–reperfusion injury in patients undergoing laparoscopic hepatectomy: a randomized double-blinded controlled trial Open
Background Hepatic ischemia–reperfusion injury (HIRI) remains a major determinant of outcomes after hepatectomy with hepatic portal occlusion. Animal studies suggest that remote ischemic postconditioning (RIPostC) could alleviate HIRI, but…
View article: Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone
Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone Open
The anti-tumor effects of CCEO in triple-negative breast cancer (TNBC) are principally mediated by (+)-2-Bornanone, which inhibits the MAPK/ERK pathway via NOX4 downregulation. These findings reveal a novel anti-tumor mechanism and provide…
View article: Analysis of the application of functional near-infrared spectroscopy in acupuncture research: a review
Analysis of the application of functional near-infrared spectroscopy in acupuncture research: a review Open
Acupuncture, as an effective external treatment method, has been widely used in various clinical diseases, but the research on its mechanism still needs to be further deepened. Functional near-infrared spectroscopy (fNIRS) technology, as a…
View article: Identification of Key Genes Governing the Effects of Physical Activity on Ferroptosis in Alzheimer’s Disease Patients: A Machine Learning-Based Study
Identification of Key Genes Governing the Effects of Physical Activity on Ferroptosis in Alzheimer’s Disease Patients: A Machine Learning-Based Study Open
Disrupted brain iron metabolism and activated ferroptosis during ageing constitute significant precursors to neurodegenerative diseases. However, whether exercise intervention can modulate ferroptosis-related genes in the central nervous s…