Yae Eun Chong
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View article: Bioanalytical considerations for quantification of ondansetron in rat microdialysis study using LC-MS/MS
Bioanalytical considerations for quantification of ondansetron in rat microdialysis study using LC-MS/MS Open
The developed LC-MS/MS method met the FDA and EMA validation criteria and was successfully applied to the in vivo pilot pharmacokinetic study. It was sensitive enough to capture the low ondansetron concentrations in brain microdialysate an…
View article: Simultaneous quantification of ondansetron and tariquidar in rat and human plasma using a high performance liquid chromatography‐ultraviolet method
Simultaneous quantification of ondansetron and tariquidar in rat and human plasma using a high performance liquid chromatography‐ultraviolet method Open
Ondansetron, a widely used antiemetic agent, is a P‐glycoprotein (P‐gp) substrate and therefore expression of P‐gp at the blood–brain barrier limits its distribution to the central nervous system (CNS), which was observed to be reversed by…