Yahui Ji
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View article: Chemical Probe Functionalized Microchip for Unbiased Capture of Extracellular Vesicles Secreted from Single Cells
Chemical Probe Functionalized Microchip for Unbiased Capture of Extracellular Vesicles Secreted from Single Cells Open
View article: Deciphering Cell–Cell Interactions with Integrative Single‐Cell Secretion Profiling
Deciphering Cell–Cell Interactions with Integrative Single‐Cell Secretion Profiling Open
Cell–cell interactions are the fundamental behaviors to regulate cellular activities. A comprehensive evaluation of intercellular interactions requires direct profiling of various signaling behaviors simultaneously at the single‐cell level…
View article: On-capillary alkylation micro-reactor: a facile strategy for proteo-metabolome profiling in the same single cells
On-capillary alkylation micro-reactor: a facile strategy for proteo-metabolome profiling in the same single cells Open
An on-capillary alkylation micro-reactor (OCAM) was developed for parallel measurement of proteome and metabolome in the same single cells, providing a new avenue for studying system biology at single-cell level.
View article: Mapping secretome-mediated interaction between paired neuron–macrophage single cells
Mapping secretome-mediated interaction between paired neuron–macrophage single cells Open
Neuron-immune interaction through secreted factors contributes significantly to the complex microenvironment in the central nervous system that could alter cell functionalities and fates in both physiological and pathological conditions, w…
View article: NOMA: a high-throughput microchip for robust, sequential measurements of secretions from the same single-cells
NOMA: a high-throughput microchip for robust, sequential measurements of secretions from the same single-cells Open
Despite recent advances in single-cell analysis technologies, lacking simple methods to keep the live single-cells traceable for longitudinal detection reliably poses a significant obstacle in single-cell secretion analysis. Here we report…
View article: Multiplexed profiling of single-cell extracellular vesicles secretion
Multiplexed profiling of single-cell extracellular vesicles secretion Open
Significance Extracellular vesicles (EVs) are cell-derived nanosized particles medicating cell−cell communication and transferring biology information molecules like nucleic acids to regulate human health and diseases. Conventional methods…
View article: Multiplexed Profiling of Single-cell Extracellular Vesicles Secretion
Multiplexed Profiling of Single-cell Extracellular Vesicles Secretion Open
Extracellular vesicles (EVs) are important intercellular mediators regulating health and disease. Conventional EVs surface marker profiling, which was based on population measurements, masked the cell-to-cell heterogeneity in the quantity …