Yajing Liu
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View article: AcGRF4-AcGIF1 chimeric protein improves the transformation and regeneration efficiency in kiwifruit
AcGRF4-AcGIF1 chimeric protein improves the transformation and regeneration efficiency in kiwifruit Open
View article: Interpersonal neural synchronization underlies interactive concept learning in older adults
Interpersonal neural synchronization underlies interactive concept learning in older adults Open
Lifelong learning is essential for active aging, yet interactive learning remains underexplored in older adults. Using fNIRS-based hyperscanning, this study investigated instructor-learner neural interactions in older learners during a con…
View article: DeepSeek in Education: Exploring the Transformative Potential of AI‐Driven Educational Intelligence
DeepSeek in Education: Exploring the Transformative Potential of AI‐Driven Educational Intelligence Open
The integration of artificial intelligence into education remains challenged by issues of scalability, interpretability, and multimodal adaptability. DeepSeek's AI‐driven educational tools show potential to improve educational applications…
View article: CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target
CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target Open
The mechanism underlying metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC) is elusive, and whether circRNA can serve as biomarker or therapeutic target for MASH/HCC needs to be systematically explore…
View article: Construct a clinical prediction model of cumulative live birth rate for IVF/ICSI in female patients of different ages
Construct a clinical prediction model of cumulative live birth rate for IVF/ICSI in female patients of different ages Open
In order to determine the number of eggs to be retrieved to maximize live birth outcomes, this study aimed to develop a clinical prediction model that would identify important predictors of cumulative live birth rate after intracytoplasmic…
View article: Lithium Exposure Causes Trophoblast Cuproptosis by Upregulating FOXO1/STEAP4 Axis in Unexplained Miscarriage
Lithium Exposure Causes Trophoblast Cuproptosis by Upregulating FOXO1/STEAP4 Axis in Unexplained Miscarriage Open
Lithium (Li) batteries have been used worldwide, but few are recycled, thus, the waste Li has been widely spread into the environment and finally accumulated in human body. Cuproptosis is a newly reported Cu‐dependent and programmed cell d…
View article: Cysteine mediates the association of essential trace elements with polycystic ovary syndrome: Does ambient particulate matters exposure modify the mediation effect of cysteine
Cysteine mediates the association of essential trace elements with polycystic ovary syndrome: Does ambient particulate matters exposure modify the mediation effect of cysteine Open
Sn, Co, and Cu were found to be negatively associated with PCOS as they positively mediated the changes in the Cys levels. In addition, exposure to PMs may modify the mediation effect of Cys on the abovementioned negative association. Furt…
View article: Unraveling the Pathway: How Physical Activity Enhances Sleep Quality Through Reduced Mobile Addiction and Maladaptive Thought Patterns in University Students
Unraveling the Pathway: How Physical Activity Enhances Sleep Quality Through Reduced Mobile Addiction and Maladaptive Thought Patterns in University Students Open
AimPhysical exercise improves sleep quality, whereas its underlying mechanisms remain underexplored. This study examines how mobile phone addiction and rumination mediate the relationship between physical exercise and college students' sle…
View article: Ambient dried metal organic frameworks aerogels with highly hydrophilic properties for fast adsorption removal of oxytetracycline
Ambient dried metal organic frameworks aerogels with highly hydrophilic properties for fast adsorption removal of oxytetracycline Open
View article: Triplet Regimen of Metronomic Capecitabine Plus Antiangiogenic Drug and PD‐1 Inhibitor as Later‐Line Salvage Treatment for Patients With MSS/pMMR Metastatic Colorectal Cancer: A Retrospective Study
Triplet Regimen of Metronomic Capecitabine Plus Antiangiogenic Drug and PD‐1 Inhibitor as Later‐Line Salvage Treatment for Patients With MSS/pMMR Metastatic Colorectal Cancer: A Retrospective Study Open
Later‐line treatment has demonstrated limited survival benefits in patients with metastatic colorectal cancer (mCRC). This retrospective study evaluated the efficacy and safety of a triplet regimen combining metronomic capecitabine, antian…
View article: Evaluation of adjunctive low-dose aspirin after non-prophylactic cerclage on the prevention of spontaneous preterm birth in singleton pregnancy: a nonrandomized controlled trial
Evaluation of adjunctive low-dose aspirin after non-prophylactic cerclage on the prevention of spontaneous preterm birth in singleton pregnancy: a nonrandomized controlled trial Open
View article: ERRATUM: Melatonin attenuates hepatic oxidative stress by regulating the P62/LC3 autophagy pathway in PCOS
ERRATUM: Melatonin attenuates hepatic oxidative stress by regulating the P62/LC3 autophagy pathway in PCOS Open
View article: Melatonin ameliorates Pb-induced mitochondrial homeostasis and ovarian damage through regulating the p38 signaling pathway
Melatonin ameliorates Pb-induced mitochondrial homeostasis and ovarian damage through regulating the p38 signaling pathway Open
Lead (Pb), a widespread metallic pollutant in the environment, has been found to have detrimental effects on the female reproduction system. Recently, our group discovered a significant correlation between toxic metals and reproductive end…
View article: The complete mitochondrial genome of Gyrodactylus pseudorasborae (Platyhelminthes: Monogenea) with a phylogeny of Gyrodactylidae parasites
The complete mitochondrial genome of Gyrodactylus pseudorasborae (Platyhelminthes: Monogenea) with a phylogeny of Gyrodactylidae parasites Open
Both the mitochondrial genome and phylogenetic analyses support G. pseudorasborae is a member of the genus Gyrodactylus and Gyrodactylidae forms an independent monophyletic clade within Gyrodactylidea. Furthermore, the mitochondrial genome…
View article: Are older adults more deceived by false advertising? Evidence from intra- and inter-brain connectivity in the prefrontal cortex during face-to-face deceptive sales
Are older adults more deceived by false advertising? Evidence from intra- and inter-brain connectivity in the prefrontal cortex during face-to-face deceptive sales Open
Financial fraud through false advertising has become increasingly prevalent among both younger and older adults, yet the neuropsychological mechanisms underlying real-time, face-to-face deceptive sales are unclear. In addition, the effects…
View article: Lithium Exposure Causes Trophoblast Cuproptosis by Up-Regulating FOXO1/STEAP4 Axis in Unexplained Miscarriage
Lithium Exposure Causes Trophoblast Cuproptosis by Up-Regulating FOXO1/STEAP4 Axis in Unexplained Miscarriage Open
View article: Melatonin attenuates hepatic oxidative stress by regulating the P62/LC3 autophagy pathway in PCOS
Melatonin attenuates hepatic oxidative stress by regulating the P62/LC3 autophagy pathway in PCOS Open
Graphical abstract The potential protective mechanisms of MT on hepatic OS in PCOS. MT could lead to a decrease in autophagy, presenting a decrease of LC3 and an increase of P62 in the PCOS liver. Increased P62 could reduce Nrf2 ubiquitina…
View article: Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a
Epigenetic editing alleviates Angelman syndrome phenotype in mice by unsilencing paternal Ube3a Open
View article: Canadian Inpatient Orthogeriatric Models of Care: A Mixed Methods Survey of Facilitators and Barriers
Canadian Inpatient Orthogeriatric Models of Care: A Mixed Methods Survey of Facilitators and Barriers Open
Background Fragility fractures are a serious and common consequence of falls in older adults. Orthogeriatric models of care reduce mortality and morbidity, but, despite this evidence, orthogeriatric programs (OGPs) are not standardized acr…
View article: Ferroptosis suppressor 1 regulates ferroptosis and mitochondrial function during mouse oocyte maturation
Ferroptosis suppressor 1 regulates ferroptosis and mitochondrial function during mouse oocyte maturation Open
Oocyte quality is critical for fertilization and embryo development. Recent studies have shown that ferroptosis may compromise oocyte quality. Ferroptosis suppressor protein 1 (FSP1) is a ferroptosis inhibitor with an undefined role in ooc…
View article: An fNIRS representation and fNIRS-scales multimodal fusion method for auxiliary diagnosis of amnestic mild cognitive impairment
An fNIRS representation and fNIRS-scales multimodal fusion method for auxiliary diagnosis of amnestic mild cognitive impairment Open
Amnestic mild cognitive impairment (aMCI) is the prodromal period of more serious neurodegenerative diseases (e.g., Alzheimer's disease), characterized by declines in memory and thinking abilities. Auxiliary assessment and early diagnosis …
View article: USP14 deficiency inhibits neointima formation following vascular injury via degradation of Skp2 protein
USP14 deficiency inhibits neointima formation following vascular injury via degradation of Skp2 protein Open
View article: LGG-10. RECOMBINANT HUMAN ENDOSTATIN IN COMBINATION WITH CHEMOTHERAPY FOR PEDIATRIC LOW-GRADE GLIOMAS
LGG-10. RECOMBINANT HUMAN ENDOSTATIN IN COMBINATION WITH CHEMOTHERAPY FOR PEDIATRIC LOW-GRADE GLIOMAS Open
BACKGROUND Pediatric low-grade gliomas (pLGGs) entail highly effective treatment regimens. In this study, we aimed to examine the efficacy and safety of recombinant human endostatin (rh-ES) combined with chemotherapy for pLGGs. METHODS We …
View article: HTR1B regulates mitochondrial homeostasis and mitophagy by activating the ERK/ MAPK signalling pathway during human embryonic arrest
HTR1B regulates mitochondrial homeostasis and mitophagy by activating the ERK/ MAPK signalling pathway during human embryonic arrest Open
View article: <italic>Lycium barbarum</italic> polysaccharide ameliorates the accumulation of lipid droplets in adipose tissue via an ATF6/SIRT1-dependent mechanism
<italic>Lycium barbarum</italic> polysaccharide ameliorates the accumulation of lipid droplets in adipose tissue via an ATF6/SIRT1-dependent mechanism Open
Lipid droplets (LDs) are dynamic organelles that store neutral lipids and are closely linked to obesity. Previous studies have suggested that Lycium barbarum polysaccharide (LBP) supplements can ameliorate obesity, but the underlyin…
View article: Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis
Oncoprotein SET-associated transcription factor ZBTB11 triggers lung cancer metastasis Open
Metastasis is the major cause of lung cancer-related death, but the mechanisms governing lung tumor metastasis remain incompletely elucidated. SE translocation (SET) is overexpressed in lung tumors and correlates with unfavorable prognosis…
View article: Elevated levels of Zn, Cu and Co are associated with an increased risk of endometriosis: Results from a case control study
Elevated levels of Zn, Cu and Co are associated with an increased risk of endometriosis: Results from a case control study Open
The risk of endometriosis was associated with elevated levels of several essential trace elements (Zn, Cu and Co). Elevated levels of these elements may be involved in the pathomechanism of endometriosis. However, further studies with larg…
View article: Agrobacterium rhizogenes-mediated marker-free transformation and gene editing system revealed that AeCBL3 mediates the formation of calcium oxalate crystal in kiwifruit
Agrobacterium rhizogenes-mediated marker-free transformation and gene editing system revealed that AeCBL3 mediates the formation of calcium oxalate crystal in kiwifruit Open
View article: R2r3-Myb Transcription Factor Gmmyb68 Is Involved in the Accumulation of Soybean Isoflavones
R2r3-Myb Transcription Factor Gmmyb68 Is Involved in the Accumulation of Soybean Isoflavones Open
View article: CDDO-imidazolide ameliorates sepsis-mediated alveolar macrophage pyroptosis by promoting mitophagy via the Nrf2/PINK1 pathway
CDDO-imidazolide ameliorates sepsis-mediated alveolar macrophage pyroptosis by promoting mitophagy via the Nrf2/PINK1 pathway Open
Background NLRP3 inflammasome-mediated alveolar macrophage pyroptosis has been reported in promoting sepsis-related acute respiratory distress syndrome(ARDS).The nuclear factor E2-related factor (Nrf2) is involved in regulating NLRP3 infla…