Explanipedia

Decoding the therapeutic potential mechanism of Cornus officinalis in Parkinson’s disease: a network pharmacology insight Open

Yuan Dong, Taotao Zhou, Yalan Deng · 2025

Background Cornus officinalis , traditionally used for its kidney-tonifying and waist-protecting properties, has recently shown potential therapeutic effects in neurological disorders. However, its mechanisms in Parkinson’s disease (PD) re…

MOF-Derived Bimetallic Catalysts for Simultaneous Irradiation Degradation and Hydrogen Evolution: Synergistic Oxidation-Reduction Processes Open

Liuxuan Cao, Yaqi Wu, Yalan Deng, Haipeng Xiao, Ruirui Ma , et al. · 2025

Electron beam (EB) irradiation technology for organic pollutant degradation primarily exploits oxidizing radicals, while concurrently generated reducing radicals remain underutilized. These reducing species represent not only wasted energy…

Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity Open

Zilong Zhao, Benxia Hu, Yalan Deng, Melinda Soeung, Jun Yao , et al. · 2025

Retraction Note: The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-κB signaling pathway Open

Shanyang He, Gang Niu, Jianhong Shang, Yalan Deng, Zhiyong Wan , et al. · 2025

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-017-0607-0.

Blood L‐cystine levels positively related to increased risk of hypertension Open

Haijun Chen, Yalan Deng, Zhou Hai-ling, Wenzhong Wu, Jinhua Bao , et al. · 2024

Hypertension is one component of metabolic syndrome (MetS). Here, the study evaluated hypertension‐associated metabolites in relation to other MetS components. Fasting plasma samples were collected from 22 hypertensive and 63 normotensive …

Targeting mitochondrial homeostasis in the treatment of non-alcoholic fatty liver disease: a review Open

Yalan Deng, Yuan Dong, Sitian Zhang, Yingmei Feng · 2024

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and its prevalence is rapidly increasing. Antioxidants, lipid-lowering medications, and lifestyle interventions are the most commonly used treatm…

LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration Open

Yalan Deng, Zilong Zhao, Marisela Sheldon, Yang Zhao, Hongqi Teng , et al. · 2024

Fe3O4 coated stent prevent artery neointimal hyperplasia by inhibiting vascular smooth muscle cell proliferation Open

Yalan Deng, Jiabing Huang, Chang Chen, Yanbing Wen, Dongxu Qiu · 2024

Author Correction: Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis Open

Yang Zhao, Jingyuan Ning, Hongqi Teng, Yalan Deng, Marisela Sheldon , et al. · 2024

2b, in which the micro-CT image used as the representative image for male Malat1-/in Fig. 2a was duplicated and presented as the representative image for the female Malat1+/+ mice.

ANGPTL3 accelerates atherosclerotic progression via direct regulation of M1 macrophage activation in plaque Open

Yuejie Zhang, Cen Yan, Yuan Dong, Jiwei Zhao, Xuanyi Yang , et al. · 2024

Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis Open

Yang Zhao, Jingyuan Ning, Hongqi Teng, Yalan Deng, Marisela Sheldon , et al. · 2024

MALAT1, one of the few highly conserved nuclear long noncoding RNAs (lncRNAs), is abundantly expressed in normal tissues. Previously, targeted inactivation and genetic rescue experiments identified MALAT1 as a suppressor of breast cancer l…

Chronic unpredictable mild stress promotes atherosclerosis <i>via</i> adipose tissue dysfunction in ApoE<sup>-/-</sup> mice Open

Min Mao, Yalan Deng, Li Wang, Gexin Zhao, Ruomei Qi , et al. · 2023

Background Chronic unpredictable mild stress (CUMS) has been shown to exacerbate atherosclerosis, but the underlying mechanism remains unknown. Adipose tissue is an energy storage organ and the largest endocrine organ in the human body, pl…

LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration Open

Yalan Deng, Zilong Zhao, Marisela Sheldon, Yang Zhao, Hongqi Teng , et al. · 2023

The molecular links between tissue repair and tumorigenesis remain elusive. Here, we report that loss of the liver tumor suppressor Lifr in mouse hepatocytes impairs the recruitment and activity of reparative neutrophils, resulting in the …

Long noncoding RNA Malat1 inhibits Tead3-Nfatc1–mediated osteoclastogenesis to suppress osteoporosis and bone metastasis Open

Yang Zhao, Hongqi Teng, Yalan Deng, Marisela Sheldon, Consuelo Martinez , et al. · 2023

MALAT1, one of the few highly conserved nuclear long noncoding RNAs (lncRNAs), is abundantly expressed in normal tissues. Previously, targeted inactivation and genetic rescue experiments identified MALAT1 as a suppressor of breast cancer l…

The role and regulation of Maf proteins in cancer Open

Yalan Deng, Liqing Lu, Huajun Zhang, Ying Fu, Ting Liu , et al. · 2023

The Maf proteins (Mafs) belong to basic leucine zipper transcription factors and are members of the activator protein-1 (AP-1) superfamily. There are two subgroups of Mafs: large Mafs and small Mafs, which are involved in a wide range of b…

Corroded iron stent increases fibrin deposition and promotes endothelialization after stenting Open

Yalan Deng, Yanbin Wen, Jun Yin, Jiabing Huang, Rongsen Zhang , et al. · 2022

Poststent restenosis is caused by insufficient endothelialization and is one of the most serious clinical complications of stenting. We observed a rapid endothelialization rate and increased fibrin deposition on the surfaces of the corrode…

RNase III coding genes modulate the cross-kingdom biofilm of Streptococcus mutans and Candida albicans Open

Yangyu Lu, Lei Lei, Yalan Deng, Hongyu Zhang, Mengying Xia , et al. · 2022

Streptococcus mutans constantly coexists with Candida albicans in plaque biofilms of early childhood caries (ECC). The progression of ECC can be influenced by the interactions between S. mutans and C. albicans through exopolysaccharides (E…

Iron corroded granules inhibiting vascular smooth muscle cell proliferation Open

Dongxu Qiu, Yalan Deng, Yanbin Wen, Jun Yin, Jie Feng , et al. · 2022

Clinical Features Differ Between Patients With Vertigo Attack Only and Weakness Attack Accompanying Vertigo Before Vertebrobasilar Stroke: A Retrospective Study Open

Yalan Deng, Lei Zhang, Rongsen Zhang, Jingfeng Duan, Jiabing Huang , et al. · 2022

Objective To determine the different clinical features of patients with vertigo attacks alone and of those with weakness accompanying vertigo attacks before the vertebrobasilar ischemic stroke. Methods In this 4-year retrospective study, w…

Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer Open

Liqing Lu, Ye Zhang, Xuemei Tan, Yulia Merkher, Sergey Leonov , et al. · 2022

Corroded Iron Stent Increased Fibrin Deposition to Promote Endothelialization after Stenting Open

Yalan Deng, Jun Yin, Jun Yin, Jiabing Huang, Yanbin Wen , et al. · 2022

Iron Corroded Granules Reduce In-Stent Restenosisby Inhibiting Vascular Smooth Muscle Cell Proliferation Open

Dongxu Qiu, Yalan Deng, Yanbin Wen, Jun Yin, Jiabing Huang , et al. · 2022

Iron Corroded Granules Inhibit the Proliferation of Vascular Smooth Muscle Cell Open

Dongxu Qiu, Yalan Deng, Yanbin Wen, Jun Yin, Jie Feng , et al. · 2022

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis Open

Fan Yao, Yalan Deng, Yang Zhao, Ying Mei, Yilei Zhang , et al. · 2021

Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance Open

Yalan Deng, Xianghou Xia, Yang Zhao, Zilong Zhao, Consuelo Martinez , et al. · 2021

The vicK gene of Streptococcus mutans mediates its cariogenicity via exopolysaccharides metabolism Open

Yalan Deng, Yingming Yang, Bin Zhang, Hong Chen, Yangyu Lu , et al. · 2021

Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance Open

Qinglei Hang, Liyong Zeng, Li Wang, Litong Nie, Fan Yao , et al. · 2021

In response to DNA double-strand breaks (DSBs), repair proteins are recruited to the damaged sites. Ubiquitin signaling plays a critical role in coordinating protein recruitment during the DNA damage response. Here, we find that the microR…

CSD 2002975: Experimental Crystal Structure Determination Open

Yalan Deng, Ling Huang, Xuehua Dong, Lei Wang, Kang Min Ok , et al. · 2021

An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely availabl…

Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy Open

Ri‐Yao Yang, Linlin Sun, Ching-Fei Li, Yuhan Wang, Jun Yao , et al. · 2021

Study on Synergistic Mechanism of Water Environment Governance in Dongting Lake Basin Based on Evolutionary Game Open

Chai Mao, Yalan Deng, Muhammad Tayyab Sohail · 2021

Watershed water environment governance has always been a research hotspot in the field of transboundary governance. Based on evolutionary game theory, the regional governments of East Dongting Lake, West Dongting Lake and South Dongting La…

Yalan Deng YOU? Author Swipe