Yong Bao
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View article: Mineralocorticoid receptor antagonists in heart failure: a systematic review and meta-analysis
Mineralocorticoid receptor antagonists in heart failure: a systematic review and meta-analysis Open
Background Mineralocorticoid receptor over-activation drives maladaptive myocardial fibrosis, vascular inflammation and renal sodium retention across the entire spectrum of left ventricular ejection fraction (LVEF). While steroidal MRAs ha…
View article: AI-Assisted Screening for Diabetic Retinopathy and Fundus Abnormalities in a Large-Scale Physical Examination Population
AI-Assisted Screening for Diabetic Retinopathy and Fundus Abnormalities in a Large-Scale Physical Examination Population Open
AI-assisted screening offers an effective, scalable approach for early DR detection and can also identify systemic diseases with retinal manifestations. Integration of AI with big data platforms enables timely intervention, especially in u…
View article: Fe2+-Coupled Organic-Substrate-Enhanced Nitrogen Removal in Two-Stage Anammox Biofilm Reactors
Fe2+-Coupled Organic-Substrate-Enhanced Nitrogen Removal in Two-Stage Anammox Biofilm Reactors Open
Anammox is a novel and energy-efficient biological nitrogen removal technology. Enhancing its performance in treating low-strength nitrogen wastewater is essential for expanding its practical applications. In response to challenges such as…
View article: Lightweight Pepper Disease Detection Based on Improved YOLOv8n
Lightweight Pepper Disease Detection Based on Improved YOLOv8n Open
China is the world’s largest producer of chili peppers, which occupy particularly important economic and social values in various fields such as medicine, food, and industry. However, during its production process, chili peppers are affect…
View article: Study on knowledge, practices, and attitudes toward decentralized clinical trials among the clinical trial practitioners in China
Study on knowledge, practices, and attitudes toward decentralized clinical trials among the clinical trial practitioners in China Open
Background Studies on the application of decentralized clinical trials (DCTs) in China are limited. This study aimed to investigate the knowledge, practices, and attitudes of clinical trial practitioners in China toward DCTs. Method An ano…
View article: Lightweight Pepper Disease Detection Based on Improved YOLOv8n
Lightweight Pepper Disease Detection Based on Improved YOLOv8n Open
China is the world's largest producer of chili peppers, which occupy particularly important economic and social values in various fields such as medicine, food and industry.However, during its production process, chili peppers are aff…
View article: Non-Local Mean Regularized Deep Image Prior: An Unsupervised Framework for Industrial Ultrasonic Tomography
Non-Local Mean Regularized Deep Image Prior: An Unsupervised Framework for Industrial Ultrasonic Tomography Open
View article: Unique Dual-Emission Fluorescent Probe that Undergoes a Sequential Two-Step Esipt Activation Mechanism for Selective Hydrazine Detection and its Multifunctional Applications
Unique Dual-Emission Fluorescent Probe that Undergoes a Sequential Two-Step Esipt Activation Mechanism for Selective Hydrazine Detection and its Multifunctional Applications Open
View article: The Influence of Pelvic Bone Dose-volume Parameters on Bone Marrow Suppression During Radiation Therapy in Patients With Stage I to III Rectal Cancer Based on Real-world Data
The Influence of Pelvic Bone Dose-volume Parameters on Bone Marrow Suppression During Radiation Therapy in Patients With Stage I to III Rectal Cancer Based on Real-world Data Open
View article: Six versus four or five cycles of first‐line etoposide and platinum‐based chemotherapy combined with thoracic radiotherapy in patients with limited‐stage small‐cell lung cancer: A propensity score‐matched analysis of a prospective randomized trial
Six versus four or five cycles of first‐line etoposide and platinum‐based chemotherapy combined with thoracic radiotherapy in patients with limited‐stage small‐cell lung cancer: A propensity score‐matched analysis of a prospective randomized trial Open
Objectives The recommended treatment for limited‐stage small‐cell lung cancer (LS‐SCLC) is a combination of thoracic radiotherapy (TRT) and etoposide plus cisplatin (EP) chemotherapy, typically administered over 4–6 cycles. Nonetheless, th…
View article: The role of MRI after neochemoradiotherapy in predicting pathological tumor regression grade and clinical outcome in patients with locally advanced rectal adenocarcinoma
The role of MRI after neochemoradiotherapy in predicting pathological tumor regression grade and clinical outcome in patients with locally advanced rectal adenocarcinoma Open
Objective To evaluate the predictive value of tumor regression grade assessed by MRI (mr-TRG) after neoadjuvant chemoradiotherapy (neo-CRT) for postoperative pathological TRG (pTRG) and prognosis in patients with locally advanced rectal ad…
View article: A study of the prognosis of patients with limited-stage small cell lung cancer who did or did not receive prophylactic cranial irradiation after effective chemoradiotherapy
A study of the prognosis of patients with limited-stage small cell lung cancer who did or did not receive prophylactic cranial irradiation after effective chemoradiotherapy Open
Objective To investigate the prognosis of patients with LS-SCLC who responded to chest chemoradiotherapy but did not receive PCI. Methods A retrospective analysis was conducted on LS-SCLC patients who had achieved complete remission (CR) o…
View article: Increased Esophageal Perforation After Combination of Anti-PD-1 Immunotherapy With Radiotherapy for Esophageal Carcinoma
Increased Esophageal Perforation After Combination of Anti-PD-1 Immunotherapy With Radiotherapy for Esophageal Carcinoma Open
View article: Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer
Efficacy of Concurrent Chemoradiotherapy With S-1 vs Radiotherapy Alone for Older Patients With Esophageal Cancer Open
ClinicalTrials.gov Identifier: NCT02813967.
View article: Five-year survival rate analysis: the combination of fortnightly-administration of endostar and concurrent chemoradiotherapy versus concurrent chemoradiotherapy in the treatment of inoperable locally advanced non-small cell lung cancer
Five-year survival rate analysis: the combination of fortnightly-administration of endostar and concurrent chemoradiotherapy versus concurrent chemoradiotherapy in the treatment of inoperable locally advanced non-small cell lung cancer Open
This study showed that the 5-year survival of those patients who received the combination treatment of Endostar and radical CCRT was significantly superior to those who received radical CCRT.
View article: Sox9+ Cell is Required for Salivary Gland Regeneration after Radiation Damage via Wnt/β-Catenin Pathway
Sox9+ Cell is Required for Salivary Gland Regeneration after Radiation Damage via Wnt/β-Catenin Pathway Open
Background: Radiotherapy for head and neck cancer can cause serious side effects, including severe damage to the salivary glands, resulting in symptoms such as xerostomia, dental caries, oral infectious and so on. Due to lack of long-term …
View article: P50.06 How much Platinum-Based Chemotherapy is Enough in Limited-Stage SCLC: A Propensity Score-Matched Analysis of a Prospective Trial
P50.06 How much Platinum-Based Chemotherapy is Enough in Limited-Stage SCLC: A Propensity Score-Matched Analysis of a Prospective Trial Open
View article: MA12.06 A Study of the Prognosis of Patients With Limited-Stage SCLC Who Did Not Receive Prophylactic Cranial Irradiation After Chemoradiotherapy
MA12.06 A Study of the Prognosis of Patients With Limited-Stage SCLC Who Did Not Receive Prophylactic Cranial Irradiation After Chemoradiotherapy Open
View article: P49.02 Simultaneous Integrated Boost IMRT (54 Gy) versus Conventional IMRT (45 Gy) Twice Daily Combined With Chemotherapy for LS-SCLC
P49.02 Simultaneous Integrated Boost IMRT (54 Gy) versus Conventional IMRT (45 Gy) Twice Daily Combined With Chemotherapy for LS-SCLC Open
View article: Chemotherapy and 21-gene recurrence score testing for older breast cancer patients: A competing-risks analysis
Chemotherapy and 21-gene recurrence score testing for older breast cancer patients: A competing-risks analysis Open
The competing-risks model is useful in dealing with multiple end events for older breast cancer patients. 21-gene RS was independently associated with BCSM. However, chemotherapy did not significantly decrease the risk of BCSM in intermedi…
View article: Colorectal cancer under 20 years old: a retrospective analysis from three tertiary hospitals
Colorectal cancer under 20 years old: a retrospective analysis from three tertiary hospitals Open
View article: Anti-PD-1 Immunotherapy and Radiotherapy for Stage IV Intrahepatic Cholangiocarcinoma: A Case Report
Anti-PD-1 Immunotherapy and Radiotherapy for Stage IV Intrahepatic Cholangiocarcinoma: A Case Report Open
Due to the unsatisfactory robustness of current predictive biomarkers in many cases, application of immunotherapy in advanced cancers with limited treatment options, such as stage IV intrahepatic cholangiocarcinoma (ICC), was quite common.…
View article: Corrigendum to ‘Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT’ [Translational Oncology 10 (2017); 1-9]
Corrigendum to ‘Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT’ [Translational Oncology 10 (2017); 1-9] Open
View article: Correction to: Timing of thoracic radiotherapy is more important than dose intensification in patients with limited-stage small cell lung cancer: a parallel comparison of two prospective studies
Correction to: Timing of thoracic radiotherapy is more important than dose intensification in patients with limited-stage small cell lung cancer: a parallel comparison of two prospective studies Open
View article: Final report of a prospective randomized study on thoracic radiotherapy target volume for limited‐stage small cell lung cancer with radiation dosimetric analyses
Final report of a prospective randomized study on thoracic radiotherapy target volume for limited‐stage small cell lung cancer with radiation dosimetric analyses Open
Background The thoracic radiotherapy (TRT) target volume for limited‐stage small‐cell lung cancer (SCLC) has been controversial for decades. In this report, the final results of a prospective randomized trial on the TRT target volume befor…
View article: ZWINT is the next potential target for lung cancer therapy
ZWINT is the next potential target for lung cancer therapy Open
View article: OA13.06 Final Report of a Prospective Randomized Study on Thoracic Radiotherapy Target Volumes with Radiation Dosimetric and Pathologic Analyses
OA13.06 Final Report of a Prospective Randomized Study on Thoracic Radiotherapy Target Volumes with Radiation Dosimetric and Pathologic Analyses Open
View article: Cervical lymph node carcinoma metastasis from unknown primary site: a retrospective analysis of 154 patients
Cervical lymph node carcinoma metastasis from unknown primary site: a retrospective analysis of 154 patients Open
Despite advances in diagnosis and treatment, the existence of cervical lymph node carcinoma of unknown primary site ( CCUP ) has always been an urgent problem worldwide. There is still no consensus on the optimal management for CCUP . In t…
View article: Dynamic changes in plasma Epstein–Barr virus DNA load during treatment have prognostic value in nasopharyngeal carcinoma: a retrospective study
Dynamic changes in plasma Epstein–Barr virus DNA load during treatment have prognostic value in nasopharyngeal carcinoma: a retrospective study Open
Circulating plasma Epstein–Barr virus DNA (EBV DNA) is related to tumor recurrence and metastasis and has potential as a dynamic, sensitive, and specific marker in nasopharyngeal carcinoma (NPC). We investigated the clinical significance o…
View article: PFKFB3 is involved in breast cancer proliferation, migration, invasion and angiogenesis
PFKFB3 is involved in breast cancer proliferation, migration, invasion and angiogenesis Open
6-Phosphofructo 2-kinase/fructose 2, 6-bisphosphatase 3 (PFKFB3) has been reported to be overexpressed in human cancer tissues and to promote the proliferation and migration of cancer cells. However, the role of PFKFB3 in the progression a…