Yuxia Ma
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View article: Sesamin alleviates drug-induced hepatotoxicity via autophagy enhancement and ferroptosis inhibition
Sesamin alleviates drug-induced hepatotoxicity via autophagy enhancement and ferroptosis inhibition Open
Our findings demonstrate that Ses attenuates APAP-induced hepatotoxicity through Foxo1, which mediates both the activation of autophagy and the inhibition of ferroptosis. It provides a new strategy for the prevention and treatment of drug-…
View article: Mentha Essential Oils: Unraveling Chemotype-Dependent Biosynthesis and Assessing Evidence for Health-Promoting Activities
Mentha Essential Oils: Unraveling Chemotype-Dependent Biosynthesis and Assessing Evidence for Health-Promoting Activities Open
Mentha essential oils (EOs), renowned for their distinctive aromas and diverse biological activities, represent a key focus in phytochemical and pharmacological research. While numerous reviews have documented the general properties of min…
View article: Trans‐Fatty Acids ( <scp>TFA</scp> ) Induced Vascular Injury Through the Regulation of the Sirt1‐Ppargc1a‐Nfe2l2 Signaling Pathway in Male Rats
Trans‐Fatty Acids ( <span>TFA</span> ) Induced Vascular Injury Through the Regulation of the Sirt1‐Ppargc1a‐Nfe2l2 Signaling Pathway in Male Rats Open
Dietary trans‐fatty acids (TFA) elevate cardiovascular disease (CVD) risk by driving vascular injury, yet the mechanisms underlying this effect remain largely unexplored. Eighteen male Sprague–Dawley (SD) rats were randomly assigned to thr…
View article: Lower and higher dietary intake of branched-chain amino acids impact cardiac structure and functions in high-fat fed LDLR -/- mice
Lower and higher dietary intake of branched-chain amino acids impact cardiac structure and functions in high-fat fed LDLR -/- mice Open
Introduction: Elevation of dietary branched-chain amino acids (BCAAs) is regarded as a risk factor for heart failure. However, exposure to lower or higher levels of BCAAs on cardiac structure and function remained unclear. Mthods: The male…
View article: Sesamin attenuates liver inflammation caused by PFOS via regulating SAP130-mediated hepatocyte-macrophage crosstalk
Sesamin attenuates liver inflammation caused by PFOS via regulating SAP130-mediated hepatocyte-macrophage crosstalk Open
This study demonstrates that Ses protects against PFOS-induced liver inflammation in mice by modulating crosstalk between hepatocytes and macrophages. Those findings support the potential of Ses as a promising natural compound for countera…
View article: Sesamin protects against Acetaminophen-induced nephrotoxicity by suppressing HMOX1-mediated apoptosis and ferroptosis
Sesamin protects against Acetaminophen-induced nephrotoxicity by suppressing HMOX1-mediated apoptosis and ferroptosis Open
Ses alleviates APAP-induced renal injury by mediating the inhibition of ferroptosis and apoptosis via HMOX1. This study provides a new strategy for the prevention and treatment of drug-induced renal injury.
View article: Serum testosterone partially mediates the adverse effects of organophosphate pesticides exposure on growth indicators of children and adolescents
Serum testosterone partially mediates the adverse effects of organophosphate pesticides exposure on growth indicators of children and adolescents Open
Environmental pollutants affect children's and adolescents' growth. However, the effect of organophosphate pesticides (OPPs) exposure on this population remains unclear. This study applied a comprehensive statistical framework to evaluate …
View article: Multifunctional and washable supramolecular hydrogels constructed from co-assembly of tannic acid and stevioside for fruit preservation
Multifunctional and washable supramolecular hydrogels constructed from co-assembly of tannic acid and stevioside for fruit preservation Open
View article: Integrative Analysis of Pharmacology and Transcriptomics Predicts Resveratrol Will Ameliorate Microplastics-Induced Lung Damage by Targeting Ccl2 and Esr1
Integrative Analysis of Pharmacology and Transcriptomics Predicts Resveratrol Will Ameliorate Microplastics-Induced Lung Damage by Targeting Ccl2 and Esr1 Open
Background: Microplastics (MPs) are ubiquitous on earth, posing a growing threat to human health. Previous studies have shown that the lung is a primary organ for MPs exposure. Resveratrol (RES) is a common dietary polyphenol that exhibits…
View article: Using three statistical methods to analyze the associations between a mixture of multi-nutrients and risk of mild cognitive impairment in an elderly population in Northern China
Using three statistical methods to analyze the associations between a mixture of multi-nutrients and risk of mild cognitive impairment in an elderly population in Northern China Open
View article: Exploring the mechanism of sesamin for the treatment of PM2.5-induced cardiomyocyte damage based on transcriptomics, network pharmacology and experimental verification
Exploring the mechanism of sesamin for the treatment of PM2.5-induced cardiomyocyte damage based on transcriptomics, network pharmacology and experimental verification Open
Introduction Exposure to fine particulate matter (PM 2.5 ) is known to be associated with cardiovascular diseases. Sesamin (Ses) is a natural phenolic compound found in sesame seeds and sesame oil. Ferroptosis is a novel mode of cell death…
View article: Association between mixed intake of multi-nutrients and cognitive function among the elderly in northern China: Three statistical models
Association between mixed intake of multi-nutrients and cognitive function among the elderly in northern China: Three statistical models Open
Few studies have considered nutrients as a mixture and their impact on MCI. The generalized linear regression (GLM), weighted quantile sum (WQS) regression, and Bayesian kernel machine regression (BKMR) models are fitted to estimate the as…
View article: The effects of mixed intake of multi-nutrients on risk of mild cognitive impairment in an elderly Population in northern china: a machine learning approach
The effects of mixed intake of multi-nutrients on risk of mild cognitive impairment in an elderly Population in northern china: a machine learning approach Open
Background Few studies have considered multi-nutrients as a mixture and their impact on Mild Cognitive Impairment(MCI). The aim of our study was to explore the health effects of mixed intake of multi-nutrients on MCI risk. Methods We measu…
View article: The effect of air filtration on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials
The effect of air filtration on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials Open
BACKGROUND Improvement of indoor air quality is beneficial for human health. However, previous studies have not reached consistent conclusions regarding the effects of indoor air filtration on inflammation and oxidative stress. OBJECTIVE T…
View article: The triarchy of L2 learners’ emotion, cognition, and language performance: Anxiety, self-efficacy, and speaking skill in lights of the emerging theories in SLA
The triarchy of L2 learners’ emotion, cognition, and language performance: Anxiety, self-efficacy, and speaking skill in lights of the emerging theories in SLA Open
Given the bond between emotion and cognition underlying the broaden-and-build theory of positive emotions, positive and negative emotions have critical roles in cognitive skills. The aim of this review was to probe into the triarchic relat…
View article: Specific ratios of macronutrient intake may help reduce the risk of depressive symptoms in people aged 55 years and older in northern China
Specific ratios of macronutrient intake may help reduce the risk of depressive symptoms in people aged 55 years and older in northern China Open
Background A growing body of evidence suggests a link between diet and depression. However, the existing research conclusions are inconsistent. Objective The purpose of this paper was to investigate the association between dietary macronut…
View article: Association of dietary patterns with blood uric acid concentration and hyperuricemia in northern Chinese adults
Association of dietary patterns with blood uric acid concentration and hyperuricemia in northern Chinese adults Open
View article: Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial
Vascular benefits of vitamin C supplementation against fine particulate air pollution in healthy adults: A double-blind randomised crossover trial Open
Evidence on the health benefits of vitamin C supplementation in highly polluted areas has not been evaluated. We aimed to evaluate whether dietary vitamin C supplementation can improve vascular health linked to particulate matter (PM) expo…
View article: The Joint Association Between Multiple Dietary Patterns and Depressive Symptoms in Adults Aged 55 and Over in Northern China
The Joint Association Between Multiple Dietary Patterns and Depressive Symptoms in Adults Aged 55 and Over in Northern China Open
Background Depression is a common psychiatric disorder in older adults that affects their health-related quality of life. Two percent of adults over the age of 55 suffer from major depression, and the prevalence of depression increases wit…
View article: The Effects of Sesamin Supplementation on Obesity, Blood Pressure, and Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
The Effects of Sesamin Supplementation on Obesity, Blood Pressure, and Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Open
Aims Sesamin, the main lignin constituent of sesame, plays a pivotal role in regulating physical state. Some studies have evidenced that the supplementation of sesamin may decrease cardiovascular disease risk. The goal of this systematic r…
View article: Dietary Patterns Are Associated With Multi-Dimensional Cognitive Functions Among Adults Aged 55 and Older in China
Dietary Patterns Are Associated With Multi-Dimensional Cognitive Functions Among Adults Aged 55 and Older in China Open
Background The intake of certain food and nutrients may play a crucial role in cognitive health. However, research on the relationship between dietary patterns and cognitive function is limited. This study aims to investigate the associati…
View article: On the Relationship Between English as a Foreign Language Learners’ Positive Affectivity, Academic Disengagement, and Communication Apprehension
On the Relationship Between English as a Foreign Language Learners’ Positive Affectivity, Academic Disengagement, and Communication Apprehension Open
This review tends to investigate the related studies on the relationships among positive affectivity as a type of positive psychology construct and academic disengagement and communication apprehension (CA) as two types of negative emotion…
View article: Associations between sedentary behaviour patterns and depression among people aged 60 and older in Hebei Province of China
Associations between sedentary behaviour patterns and depression among people aged 60 and older in Hebei Province of China Open
Background Sedentary behaviours (SBs) are now considered a risk factor for depression. Older adults are sedentary most of the time and are at a high risk of depression. However, not all types of SBs have adverse effects on mental health. P…
View article: Inhibitors of IFN Gene Stimulators (STING) Improve Intestinal Ischemia-Reperfusion Induced Acute Lung Injury by Activating AMPK Signal
Inhibitors of IFN Gene Stimulators (STING) Improve Intestinal Ischemia-Reperfusion Induced Acute Lung Injury by Activating AMPK Signal Open
Background: Acute lung injury (ALI) caused by intestinal ischemia-reperfusion is a life-threatening disease. Interferon gene stimulator ( STING ) is a cytoplasmic DNA sensor, participating in the initiation of inflammatory response. This s…
View article: Associations Between Dietary Inflammatory Index and Sex Hormones Among 6- to 19-Year-Old Children and Adolescents in NHANES 2015–2016
Associations Between Dietary Inflammatory Index and Sex Hormones Among 6- to 19-Year-Old Children and Adolescents in NHANES 2015–2016 Open
Objectives This study aimed to assess the relationship between dietary inflammatory index (DII) and sex steroids in children (6-11 years old) and adolescents (12-19 years old) in the U.S. National Health and Nutrition Examination Survey, 2…
View article: Cardiovascular Benefits of Vitamin C Supplementation Against Particulate Air Pollution in Healthy Adults: A Double-Blind Randomized Crossover Trial
Cardiovascular Benefits of Vitamin C Supplementation Against Particulate Air Pollution in Healthy Adults: A Double-Blind Randomized Crossover Trial Open
Background: Accumulating evidence indicates that ambient air pollution exposure is associated with the adverse effects of cardiovascular diseases (CVDs). Evidence on the health benefits of vitamin C supplementation in highly polluted areas…
View article: Association of Dietary Inflammatory Index (DII) and Depressive Disorders
Association of Dietary Inflammatory Index (DII) and Depressive Disorders Open
A lot of evidence shows that inflammation is related to the development of depression. However, the heterogeneity of depression hinders efforts to understand, prevent and treat this disease. The purpose of this comprehensive review is to s…
View article: Role of BMI in the Relationship Between Dietary Inflammatory Index and Depression: An Intermediary Analysis
Role of BMI in the Relationship Between Dietary Inflammatory Index and Depression: An Intermediary Analysis Open
Introduction: This study investigated this association and the role of BMI in the inflammatory process in a large population-based observational study. Methods: A total of 1,865 elderly people (≥55 years) were followed from the Community C…
View article: Association of dietary inflammatory index and metabolic syndrome in the elderly over 55 years in Northern China
Association of dietary inflammatory index and metabolic syndrome in the elderly over 55 years in Northern China Open
We assessed the association between the dietary inflammatory index (DII) and the development of metabolic syndrome in the elderly over 55 years in Northern China. The data of 1936 Chinese adults aged 55 years and over from a community-base…
View article: Investigating Associations Between Depressive Symptoms and Anti-/Pro-Inflammatory Nutrients in an Elderly Population in Northern China: A Bayesian Kernel Machine Regression Approach
Investigating Associations Between Depressive Symptoms and Anti-/Pro-Inflammatory Nutrients in an Elderly Population in Northern China: A Bayesian Kernel Machine Regression Approach Open
We determined the combined effect of multiple nutrients of different inflammatory potential classifications on depressive symptoms in the elderly.