Xiaohong Chen
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View article: Metabolically hijacked Listeria monocytogenes synergizes STING activation and dual cell death for enhanced antitumor immunotherapy
Metabolically hijacked Listeria monocytogenes synergizes STING activation and dual cell death for enhanced antitumor immunotherapy Open
These findings establish metabolic hijacking of bacterial vectors as a paradigm-shifting strategy that integrates direct tumor killing with multimodal immune activation, overcoming key barriers in microbial immunotherapy.
View article: Establishment of a Tissue Culture System for Quercus palustris
Establishment of a Tissue Culture System for Quercus palustris Open
Quercus palustris possesses significant ecological and ornamental value, yet its clonal propagation remains challenging, hindering germplasm utilization. To address this, an efficient tissue culture propagation system was established. This…
View article: Risk Assessment of Roof Water Inrush in Shallow Buried Thick Coal Seam Using FAHP-CV Comprehensive Weighting Method: A Case Study of Guojiawan Coal Mine
Risk Assessment of Roof Water Inrush in Shallow Buried Thick Coal Seam Using FAHP-CV Comprehensive Weighting Method: A Case Study of Guojiawan Coal Mine Open
Roof water inrush is a major hazard threatening coal mine safety. This paper addresses the risk of roof water inrush during mining in the shallow-buried Jurassic coalfield of Northern Shaanxi, taking the Guojiawan Coal Mine as a case study…
View article: Disparities in urban vegetation degradation and heat exposure during drought periods in U.S. cities
Disparities in urban vegetation degradation and heat exposure during drought periods in U.S. cities Open
Policymakers are increasingly recognizing the necessity for the equitable distribution of urban green spaces across sociodemographic groups. Nevertheless, the extant research consistently highlights disparities in this allocation, frequent…
View article: Impact of Non‐Alcoholic Fatty Liver Disease on the <scp>HBsAg</scp> Loss of Patients With Chronic Hepatitis B Treated in Pegylated Interferon Alpha
Impact of Non‐Alcoholic Fatty Liver Disease on the <span>HBsAg</span> Loss of Patients With Chronic Hepatitis B Treated in Pegylated Interferon Alpha Open
Whether combining non‐alcoholic fatty liver disease (NAFLD) affects the efficacy of pegylated interferon alpha (PEG‐IFN‐α) for patients with chronic hepatitis B (CHB) remains unknown; hence, we aimed to conduct a retrospective cohort study…
View article: Case Report: The case of atypical OAPS complicated by positive anti-SSA and anti-SSB antibodies
Case Report: The case of atypical OAPS complicated by positive anti-SSA and anti-SSB antibodies Open
Antiphospholipid syndrome (APS) is a systemic autoimmune disease. When pathological pregnancy manifestations—such as recurrent miscarriage, stillbirth, preeclampsia, and preterm birth—predominate, the condition is called obstetric APS (OAP…
View article: Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort
Genetic susceptibility to gestational diabetes and its mild modification by bisphenol A and thyroid-stimulating hormone: findings from a South Chinese pregnancy cohort Open
Background Gestational diabetes mellitus (GDM) is a multifaceted and complex condition. Genetic factors, maternal exposure to bisphenol A (BPA), and thyroid-stimulating hormone (TSH) levels have been associated with GDM. However, existing …
View article: Galactic cosmic rays, propagation, gamma-rays and neutrinos
Galactic cosmic rays, propagation, gamma-rays and neutrinos Open
Plenary talk presented at the XXI International Workshop on Neutrino Telescopes - Padova 29 September - 3 October 2025 (https://agenda.infn.it/event/44606/)
View article: Impact of surgery on survival in TNBC with bone metastases only: a propensity score-matched SEER database analysis
Impact of surgery on survival in TNBC with bone metastases only: a propensity score-matched SEER database analysis Open
In TNBC patients with bone metastases only, compared to the non-surgery group, the primary site surgery group shows longer OS and CSS. Surgery combined with systemic treatment is a preferable treatment option.
View article: Cardiac Angiosarcoma With Lung Metastasis Presenting as Granuloma‐Like Lesions: One Case Report and Literature Review
Cardiac Angiosarcoma With Lung Metastasis Presenting as Granuloma‐Like Lesions: One Case Report and Literature Review Open
Metastatic pulmonary angiosarcoma exhibits highly heterogeneous clinical, imaging and pathological features, with an extremely poor prognosis. This case report describes a 30‐year‐old woman who presented with recurrent hemoptysis and multi…
View article: Adaptive Challenges of Past and Future Invasion of <i>Drosophila suzukii</i> : Insights From Novel Genomic Resources and Statistical Methods Combining Individual and Pool Sequencing Data
Adaptive Challenges of Past and Future Invasion of <i>Drosophila suzukii</i> : Insights From Novel Genomic Resources and Statistical Methods Combining Individual and Pool Sequencing Data Open
Global change is accelerating biological invasions, making it crucial to understand how species adapt in new environments to improve management strategies. Genomic data provide valuable insights into adaptation through genotype‐environment…
View article: Comparative Analysis of Environmental and Host-Associated Microbiome in Odorrana schmackeri (Auran: Ranidae): Insights into Tissue-Specific Colonization and Microbial Adaptation
Comparative Analysis of Environmental and Host-Associated Microbiome in Odorrana schmackeri (Auran: Ranidae): Insights into Tissue-Specific Colonization and Microbial Adaptation Open
Amphibian microbial communities are known to be shaped by host physiology and environmental factors, yet the relative roles of sexual dimorphism and tissue specialization remain poorly understood. Using 16S rRNA gene sequencing, we compare…
View article: A real geographical case study on superconducting cables for high speed railway with electromagnetic and environmental analysis
A real geographical case study on superconducting cables for high speed railway with electromagnetic and environmental analysis Open
High-speed railways offer significant benefits such as high speed and large passenger capacity. However, their overall energy consumption continues to increase with network expansion. High-temperature superconducting (HTS) cables represent…
View article: Effects of Different Forms of Selenium in Human Umbilical Cord Mesenchymal Stem Cells
Effects of Different Forms of Selenium in Human Umbilical Cord Mesenchymal Stem Cells Open
Background: Mesenchymal stem cells (MSCs) have shown positive therapeutic effects on various diseases; however, their functionality can decline during in vitro expansion. Selenium (Se) supplementation has emerged as a strategy for enhancin…
View article: Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway
Epimedium brevicornu Maxim. extract activates natural killer cells against hepatocellular carcinoma via the cGAS-STING pathway Open
Background Epimedium brevicornu : Maxim., a traditional Chinese botanical drug, has shown significant therapeutic effects against hepatocellular carcinoma (HCC), with its flavonoid compounds exhibiting anti-HCC activity through various mec…
View article: Gut microbiota and colorectal cancer: mechanistic insights, diagnostic advances, and microbiome-based therapeutic strategies
Gut microbiota and colorectal cancer: mechanistic insights, diagnostic advances, and microbiome-based therapeutic strategies Open
Colorectal cancer (CRC) is closely linked to gut microbiota dysbiosis. We synthesize evidence that carcinogenic microbes promote CRC through chronic inflammation, bacterial genotoxins, and metabolic imbalance, highlighting key pathways inv…
View article: DuMES: Deep Reinforcement Learning‐Based EV Charging Scheduling With Dual‐Layer Safety Modules
DuMES: Deep Reinforcement Learning‐Based EV Charging Scheduling With Dual‐Layer Safety Modules Open
Deep reinforcement learning (DRL) has become a promising approach for electric vehicle (EV) charging scheduling. However, its practical deployment poses potential risks to power infrastructure. DRL relies on trial‐and‐error interactions du…
View article: Efficient separation of 1,5-dimethyl-2-pyrrolidone from <i>N</i> -methylpyrrolidone enabled by pore confinement
Efficient separation of 1,5-dimethyl-2-pyrrolidone from <i>N</i> -methylpyrrolidone enabled by pore confinement Open
The pore-sieving effect of carbon materials enables efficient removal of 1,5-dimethyl-2-pyrrolidone (DMP) from N -methylpyrrolidone (NMP) through thermodynamic and kinetic regulation.
View article: Global and regional burden, temporal trends, and projections of chronic pain from 1990 to 2032, and its association with cardiovascular diseases: analyses based on global burden of diseases study 2021
Global and regional burden, temporal trends, and projections of chronic pain from 1990 to 2032, and its association with cardiovascular diseases: analyses based on global burden of diseases study 2021 Open
Introduction Chronic pain is a major global health problem that significantly affects quality of life and increases the risk of cardiovascular diseases. Methods Using the Global Burden of Disease (GBD) 2021 data, this study analyzed tempor…