Yanling Hu
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View article: High-Temperature Induction of 2n Female Gametes to Produce Triploid Birches: Timing, Parameters, and Growth Outcomes
High-Temperature Induction of 2n Female Gametes to Produce Triploid Birches: Timing, Parameters, and Growth Outcomes Open
Triploids are typically formed through the fusion of a haploid gamete from a diploid organism and a diploid gamete from a tetraploid organism or through chromosome doubling in gametes by other means. To circumvent the multi-year flowering …
View article: Interfacial Diffusion and Copper Alloy Layer Wear Mechanism in Cu-20Pb-5Sn/45 Steel Bimetallic Composites
Interfacial Diffusion and Copper Alloy Layer Wear Mechanism in Cu-20Pb-5Sn/45 Steel Bimetallic Composites Open
Cu-20Pb-5Sn/45 steel bimetallic composites were prepared using the solid–liquid composite method. The interfacial microstructure, bonding strength, and wear performance were systematically characterized to elucidate the mechanisms governin…
View article: Understanding drug anaphylactic shock: A narrative review on its recognition and first aid strategies
Understanding drug anaphylactic shock: A narrative review on its recognition and first aid strategies Open
Drug allergies are the most common cause of fatal anaphylaxis and a public health problem that plagues every clinician. Based on the actual situation of clinical nursing, the author consulted the latest guidelines, expert consensus, litera…
View article: The critical role of diet, exercise, and sleep in shaping the gut microbiota of children with idiopathic short stature: a Retrospective study
The critical role of diet, exercise, and sleep in shaping the gut microbiota of children with idiopathic short stature: a Retrospective study Open
Objectives To investigate the gut microbiota in children with varying degrees of idiopathic short stature (ISS) and to examine the relationship between their intestinal microbiota and lifestyle factors, including diet, exercise, medication…
View article: The human gut microbiota is associated with host lifestyle: a comprehensive narrative review
The human gut microbiota is associated with host lifestyle: a comprehensive narrative review Open
Background The gut microbiota serves as a critical interface between lifestyle factors and host physiology. Despite extensive research on individual domains including diet, sleep, and exercise, an integrated understanding of their synergis…
View article: Dysbiosis of gut microbiota with enriched pro-inflammatory species in children with idiopathic short stature: a case-control study
Dysbiosis of gut microbiota with enriched pro-inflammatory species in children with idiopathic short stature: a case-control study Open
Idiopathic short state (ISS) demotes a condition of diminished height in children lacking identifiable pathological etiologies, emering as a prominent elements, can precipitate ISS. We explored the prevalence, variability, organization, an…
View article: Causal relationship between hepatic function indicators and thrombocytopenia risk in early-stage hepatitis B virus infection: evidence from clinical observational studies and mendelian randomization analyses
Causal relationship between hepatic function indicators and thrombocytopenia risk in early-stage hepatitis B virus infection: evidence from clinical observational studies and mendelian randomization analyses Open
Background Thrombocytopenia is a common occurrence in patients with hepatitis B virus (HBV) infection, particularly in those with liver cirrhosis. However, it can also manifest in the early stages of HBV infection, before the onset of live…
View article: Adherence to phase I cardiac rehabilitation in post-PCI patients: a latent class analysis
Adherence to phase I cardiac rehabilitation in post-PCI patients: a latent class analysis Open
Background Coronary heart disease seriously jeopardizes human health and has become a principal public health problem of global concern. While percutaneous coronary intervention (PCI) repairs narrowed arteries and extends patients' lives, …
View article: Research focus and emerging trends of the gut microbiome and infant: a bibliometric analysis from 2004 to 2024
Research focus and emerging trends of the gut microbiome and infant: a bibliometric analysis from 2004 to 2024 Open
Background Over the past two decades, gut microbiota has demonstrated unprecedented potential in human diseases and health. The gut microbiota in early life is crucial for later health outcomes. This study aims to reveal the knowledge coll…
View article: Comprehensive bioinformatics analysis of human cytomegalovirus pathway genes in pan-cancer
Comprehensive bioinformatics analysis of human cytomegalovirus pathway genes in pan-cancer Open
Background Human cytomegalovirus (HCMV) is a herpesvirus that can infect various cell types and modulate host gene expression and immune response. It has been associated with the pathogenesis of various cancers, but its molecular mechanism…
View article: Inspecting mother-to-infant microbiota transmission: disturbance of strain inheritance by cesarian section
Inspecting mother-to-infant microbiota transmission: disturbance of strain inheritance by cesarian section Open
Introduction The initial acquisition and subsequent development of the microbiota in early life is crucial to future health. Cesarean-section (CS) birth is considered to affect early microbial transmission from mother to infant. Methods In…
View article: CagA-positive Helicobacter pylori may promote and aggravate scrub typhus
CagA-positive Helicobacter pylori may promote and aggravate scrub typhus Open
Helicobacter pylori ( H. pylori ) infection may alter the host’s resistance to tsutsugamushi disease pathogens through the Th1 immune response, leading to potential synergistic pathogenic effects. A total of 117 scrub typhus cases at Beiha…
View article: Antibiotic resistance profiles of gut microbiota across various primate species in Guangxi
Antibiotic resistance profiles of gut microbiota across various primate species in Guangxi Open
Introduction Understanding the gut microbiota and antibiotic resistance gene (ARG) profiles in non-human primates (NHPs) is crucial for evaluating their potential impact on human health and the environment. Methods In this study, we perfor…
View article: Antibiotic Resistance Profiles of Gut Microbiota Across Various Primate Species in Guangxi
Antibiotic Resistance Profiles of Gut Microbiota Across Various Primate Species in Guangxi Open
Understanding the gut microbiota and antibiotic resistance gene (ARG) profiles in non-human primates (NHPs) is crucial for evaluating their potential impact on human health and the environment. In this study, we performed metagenomic analy…
View article: Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress
Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress Open
Lysosomal clearance of proteotoxic stressors through autophagy is an essential process underlying cellular homeostasis. Its failure can lead to cell death1,2, by initiating apoptotic pathways3–11. However, in aging and neurodegenerative di…
View article: Disparity of HIV-1 Pretreatment Drug Resistance in Men Who Have Sex With Men and the Heterosexual Population in Guangxi, China
Disparity of HIV-1 Pretreatment Drug Resistance in Men Who Have Sex With Men and the Heterosexual Population in Guangxi, China Open
Background The prevalence of human immunodeficiency type 1 (HIV-1) pretreatment drug resistance (PDR) in men who have sex with men (MSM) in Guangxi remains unclear, and its effect on antiretroviral therapy (ART) needs to be further studied…
View article: Exercise-induced circulating exosomes potentially prevent pelvic organ prolapse in clinical practice via inhibition of smooth muscle apoptosis
Exercise-induced circulating exosomes potentially prevent pelvic organ prolapse in clinical practice via inhibition of smooth muscle apoptosis Open
Our study proved that AXUD1 is a good clinical diagnostic indicator for POP and provided a theoretical basis for future prevention of POP through exercise and a potential target for intervention in muscle dysfunction.
View article: GRID2 aberration leads to disturbance in neuroactive ligand-receptor interactions via changes to the species richness and composition of gut microbes
GRID2 aberration leads to disturbance in neuroactive ligand-receptor interactions via changes to the species richness and composition of gut microbes Open
Compared with the WT group, the defective GRID2 gene affected the species richness and composition of gut microbes in the GRID2(±) mice, which in turn affected the function of gut microbes, leading to the disruption of neuroactive ligand-r…
View article: Hyperglycemia may increase deep vein thrombosis in trauma patients with lower limb fracture
Hyperglycemia may increase deep vein thrombosis in trauma patients with lower limb fracture Open
Diabetes mellitus is associated with prothrombotic states and thrombotic events. This study examined the association between preoperative glucose levels and deep vein thrombosis (DVT) in trauma patients undergoing surgery for lower limb fr…
View article: Human parainfluenza 3 and respiratory syncytial viruses detected in pangolins
Human parainfluenza 3 and respiratory syncytial viruses detected in pangolins Open
Pangolins have gained increasing global attention owing to their public health significance as potential zoonotic hosts since the identification of SARS-CoV-2-related viruses in them. Moreover, these animals could carry other respiratory v…
View article: Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing
Comparative Gut Microbiome in Trachypithecus leucocephalus and Other Primates in Guangxi, China, Based on Metagenome Sequencing Open
The Trachypithecus leucocephalus (white-headed langur) is a highly endangered, karst-endemic primate species, inhabiting the karst limestone forest in Guangxi, Southwest China. How white-headed langurs adapted to karst limestone and specia…
View article: Immunomodulatory effect of Ganoderma lucidum polysaccharide extract on peritoneal macrophage function of BALB/c mice
Immunomodulatory effect of Ganoderma lucidum polysaccharide extract on peritoneal macrophage function of BALB/c mice Open
Ganoderma lucidum has been suggested as a natural immunomodulator. It is not yet clear exactly which combination of this extract is responsible for its immunomodulatory effects. Still, it appears that the 3-complement (CR3) receptor on the…
View article: Natural infection of pangolins with human respiratory syncytial viruses
Natural infection of pangolins with human respiratory syncytial viruses Open
Respiratory syncytial virus (RSV) is an enveloped non-segmented negative sense RNA virus that belongs to Orthopneumovirus genus of the Pneumoviridae family in the order Mononegavirales. The virus is the leading cause of severe respiratory …
View article: Screening and Identification of Human Endogenous Retrovirus-K mRNAs for Breast Cancer Through Integrative Analysis of Multiple Datasets
Screening and Identification of Human Endogenous Retrovirus-K mRNAs for Breast Cancer Through Integrative Analysis of Multiple Datasets Open
Objective Human endogenous retroviruses (HERVs) make up 8% of the human genome. HERVs are biologically active elements related to multiple diseases. HERV-K, a subfamily of HERVs, has been associated with certain types of cancer and suggest…