Yanming Chen
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View article: Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease
Spatial transcriptomics uncovers lipid metabolic dysregulation driving immune-stroma crosstalk in Sjögren's Disease Open
National Natural Science Foundation of China (82104484,32301084), Joint funding from schools (colleges) and enterprises in Guangzhou (2025A03J3203, 2024A03J0987), Natural Science Foundation of Guangdong Province (2023A1515012790), Guangdon…
View article: Intelligent Detection of Residual Carious Tissue During Caries Removal Using an Improved YOLOv8 Model
Intelligent Detection of Residual Carious Tissue During Caries Removal Using an Improved YOLOv8 Model Open
Objective:This study aimed to develop a prototype of an AI-based recognition system for identifying residual carious tissue during caries removal by improving the YOLOv8 model. The goal was to provide preliminary theoretical and technical …
View article: Tirzepatide retention in iWAT with mesoporous polydopamine encapsulation enhances weight loss through leptin receptor signaling
Tirzepatide retention in iWAT with mesoporous polydopamine encapsulation enhances weight loss through leptin receptor signaling Open
These findings indicate that the retention of TZP in iWAT via MPDA encapsulation amplified its effect on weight loss in mice through leptin receptor signaling compared with TZP alone, which provides new insights into the tissue-specific me…
View article: Bacteriophages Combined with Hybridized Nanoflower-based Electrochemical Biosensor for the Specific and Rapid Detection of Live Acinetobacter baumannii in Real Samples
Bacteriophages Combined with Hybridized Nanoflower-based Electrochemical Biosensor for the Specific and Rapid Detection of Live Acinetobacter baumannii in Real Samples Open
Acinetobacter baumannii is an opportunistic nosocomial bacterial pathogen that causes significant global morbidity and mortality. A rapid and accurate detection platform is essential to minimize the risk of nosocomial infections and drug r…
View article: Symmetry-Driven Two-Population Collaborative Differential Evolution for Parallel Machine Scheduling in Lace Dyeing with Probabilistic Re-Dyeing Operations
Symmetry-Driven Two-Population Collaborative Differential Evolution for Parallel Machine Scheduling in Lace Dyeing with Probabilistic Re-Dyeing Operations Open
In lace textile manufacturing, the dyeing process in parallel machine environments faces challenges from sequence-dependent setup times due to color family transitions, machine eligibility constraints based on weight capacities, and probab…
View article: Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation
Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation Open
Proteotoxicity induced by misfolded or aggregated proteins causes progressive neuronal damage. The endoplasmic reticulum (ER) protein quality control (ERQC) pathways are responsible for mitigating the accumulation of these misfolded or agg…
View article: Innovative Design to Control Spartina Alterniflora
Innovative Design to Control Spartina Alterniflora Open
In order to effectively curb the rapid growth trend in Spartina alterniflora in coastal cities of China, this study proposes an innovative mechanical equipment design scheme for eradicating Spartina alterniflora. Based on literature analys…
View article: Research on willow furniture design based on Kano-AHP and TRIZ
Research on willow furniture design based on Kano-AHP and TRIZ Open
Willow wood furniture has become one of the most popular types of wood furniture in the Chinese furniture market. Research was undertaken to solve the pain points of product design and meet the requirements of green development. Firstly, t…
View article: Structure, Mechanical Properties and Water Vapor Corrosion Resistance of AlCrNbSiTiN High-Entropy Nitride Coatings Deposited by RF Magnetron Sputtering
Structure, Mechanical Properties and Water Vapor Corrosion Resistance of AlCrNbSiTiN High-Entropy Nitride Coatings Deposited by RF Magnetron Sputtering Open
High-entropy nitride AlCrNbSiTiN coatings were deposited by RF magnetron sputtering at different bias voltages. The structure, mechanical properties and water vapor corrosion resistance of the coatings were systematically studied. The coat…
View article: Carotid atherosclerosis associated with tau pathology and cognitive function in cognitively intact adults: the CABLE study
Carotid atherosclerosis associated with tau pathology and cognitive function in cognitively intact adults: the CABLE study Open
Background Carotid atherosclerosis has been implicated in cognitive decline, but the evidence from current studies is insufficient and the detailed mechanism remains unclear. Objective This study aimed to explore the association of carotid…
View article: Enhancing diabetic wound healing through anti-bacterial and promoting angiogenesis using dual-functional slow-release microspheres-loaded dermal scaffolds
Enhancing diabetic wound healing through anti-bacterial and promoting angiogenesis using dual-functional slow-release microspheres-loaded dermal scaffolds Open
Bacterial infections and the degeneration of the capillary network comprise the primary factors that contribute to the delayed healing of diabetic wounds. However, treatment modalities that cater to effective diabetic wounds healing in cli…
View article: Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesis
Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesis Open
The prevalent RNA alternative splicing (AS) contributes to molecular diversity, which has been demonstrated in cellular function regulation and disease pathogenesis. However, the contribution of AS in pancreatic islets during diabetes prog…
View article: Study on non‐isothermal crystallization kinetics of Poly (butylene terephthalate)/Poly (ethylene terephthalateco‐1,4‐cylclohexylenedimethylene terephthalate) blends
Study on non‐isothermal crystallization kinetics of Poly (butylene terephthalate)/Poly (ethylene terephthalateco‐1,4‐cylclohexylenedimethylene terephthalate) blends Open
Poly (butylene terephthalate) (PBT)/poly (ethylene glycol‐co‐cyclohexane‐1, 4‐dimethanolterephthalate) (PETG) blends were prepared by melt blending using a twin screw extruder. The non‐isothermal crystallization behaviors of PBT/PETG blend…
View article: Cellular communication network factor 1 promotes retinal leakage in diabetic retinopathy via inducing neutrophil stasis and neutrophil extracellular traps extrusion
Cellular communication network factor 1 promotes retinal leakage in diabetic retinopathy via inducing neutrophil stasis and neutrophil extracellular traps extrusion Open
Background Diabetic retinopathy (DR) is a major cause of blindness and is characterized by dysfunction of the retinal microvasculature. Neutrophil stasis, resulting in retinal inflammation and the occlusion of retinal microvessels, is a ke…
View article: Cellular communication network factor 1 promotes retinal leakage in diabetic retinopathy via inducing neutrophil stasis and neutrophil extracellular traps extrusion
Cellular communication network factor 1 promotes retinal leakage in diabetic retinopathy via inducing neutrophil stasis and neutrophil extracellular traps extrusion Open
Background Diabetic retinopathy (DR) is a major cause of blindness and is characterized by dysfunction of the retinal microvasculature. Neutrophil stasis, resulting in retinal inflammation and the occlusion of retinal microvessels, is a ke…
View article: Research on Innovative Design of Towable Caravans Integrating Kano-AHP and TRIZ Theories
Research on Innovative Design of Towable Caravans Integrating Kano-AHP and TRIZ Theories Open
The caravan industry in China is facing significant challenges, primarily because the mode of caravan travel is relatively niche within the country and the industry as a whole has had a slow start. This has ultimately resulted in a mismatc…
View article: A Nonlocal Filter for SAR Interferometric Phase Based on Partial Siamese Network
A Nonlocal Filter for SAR Interferometric Phase Based on Partial Siamese Network Open
Filtering is a crucial step in synthetic aperture radar (SAR) interferometric phase processing. In the context of rapid development in deep learning, the interferometric phase filtering networks have demonstrated more powerful filtering ca…