Yanan Zhu
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View article: Vital Pulp Therapy Of Mature Permanent Molar With Irreversible Pulpitis
Vital Pulp Therapy Of Mature Permanent Molar With Irreversible Pulpitis Open
Introduction: Vital pulp therapy (VPT) has been advocated for its advantages in preserving tooth vitality. In this case, a mature permanent molar diagnosed with irreversible pulpitis and asymptomatic apical periodontitis was treated by VPT…
View article: Microbiota In High-Caries Patients And Cross-Species Biofilm Validation
Microbiota In High-Caries Patients And Cross-Species Biofilm Validation Open
Aim or purpose: Screening the core microbiota of high-caries-risk patients and conducting an in vitro study on the cariogenicity of multi-species mixed biofilm. Materials and methods: From October 2022 to April 2023, seven adult patients w…
View article: A quantum computing approach to beam angle optimization.
A quantum computing approach to beam angle optimization. Open
The findings highlight the potential of quantum-inspired algorithm to enhance the solution to BAO problem by demonstrated improvement in plan quality using the proposed method, QC-BAO. This study paves the way for future clinical implement…
View article: Dexamethasone induces transgenerational inheritance of fetal-derived glomerulosclerosis phenotype in offspring through GR/DNMT3a mediated alterations of the lncRNA-Meg3/Notch signaling pathway
Dexamethasone induces transgenerational inheritance of fetal-derived glomerulosclerosis phenotype in offspring through GR/DNMT3a mediated alterations of the lncRNA-Meg3/Notch signaling pathway Open
Prenatal dexamethasone exposure (PDE) has been reported to be associated with negative pregnancy outcomes and increased susceptibility to chronic diseases in their offspring. This study aimed to explore the transgenerational effects and me…
View article: A fully flexible joint lattice position and dose optimization method for LATTICE therapy.
A fully flexible joint lattice position and dose optimization method for LATTICE therapy. Open
A new LATTICE treatment planning approach with fully flexible joint lattice position and dose optimization is introduced and demonstrated to improve target PVDR and OAR sparing, compared to conventional LATTICE method with regular placemen…
View article: An energy optimization method based on mixed-integer model and variational quantum computing algorithm for faster IMPT.
An energy optimization method based on mixed-integer model and variational quantum computing algorithm for faster IMPT. Open
Intensity-modulated proton therapy (IMPT) offers superior dose conformity with reduced exposure to surrounding healthy tissues compared to conventional photon therapy. Improving IMPT delivery efficiency reduces motion-related uncertainties…
View article: FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway
FTO-associated osteoclastogenesis promotes alveolar bone resorption in apical periodontitis male rat via the HK1/USP14/RANK pathway Open
View article: Different exercise interventions on quality of sleep in breast cancer survivors—a network meta-analysis of randomized controlled trials
Different exercise interventions on quality of sleep in breast cancer survivors—a network meta-analysis of randomized controlled trials Open
Introduction Breast cancer is currently the most prevalent cancer globally; however, it generally has a favorable prognosis and is linked to a high survival rate. While effective treatments can extend survival and mitigate associated side …
View article: Multi-IMPT: a biologically equivalent approach to proton ARC therapy
Multi-IMPT: a biologically equivalent approach to proton ARC therapy Open
Objective: Proton spot-scanning arc therapy (ARC) is an emerging modality that can improve the high-dose conformity to targets compared with standard intensity-modulated proton therapy (IMPT). However, the efficient treatment delivery of A…
View article: Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus
Glycolysis inhibition functionally reprograms T follicular helper cells and reverses lupus Open
Summary Systemic lupus erythematosus (SLE) is an autoimmune disease in which the production of pathogenic autoantibodies depends on T follicular helper (T FH ) cells. This study was designed to investigate the mechanisms by which inhibitio…
View article: Multiple Electron Transfer in Semiconductive Ternary D‐D'‐A Metal‐Organic Framework for Enhanced X‐Ray Detection and Imaging
Multiple Electron Transfer in Semiconductive Ternary D‐D'‐A Metal‐Organic Framework for Enhanced X‐Ray Detection and Imaging Open
Semiconductive metal–organic frameworks (MOFs) with donor–acceptor (D–A) characteristics have garnered attractive attention due to their capacity for separating and transferring photogenerated charges, making them promising candidates for …
View article: ACCURATE PROTON-PHOTON PATIENT SELECTION VIA DOSE AND NTCP PREDICTION FOR HEAD-AND-NECK PATIENTS
ACCURATE PROTON-PHOTON PATIENT SELECTION VIA DOSE AND NTCP PREDICTION FOR HEAD-AND-NECK PATIENTS Open
View article: IMPROVING DOSE CONFORMALITY FOR PROTON LATTICE VIA PROTON ARC THERAPY
IMPROVING DOSE CONFORMALITY FOR PROTON LATTICE VIA PROTON ARC THERAPY Open
View article: Mitochondria-mediated ferroptosis induced by CARD9 ablation prevents MDSCs-dependent antifungal immunity
Mitochondria-mediated ferroptosis induced by CARD9 ablation prevents MDSCs-dependent antifungal immunity Open
View article: Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin Open
STUDY QUESTION Does palmitic acid (PA), the most common saturated free fatty acid (FFA) in individuals with obesity, contribute to anovulation through upregulation of the collagen-crosslinking enzyme lysyl oxidase (LOX) in the ovary? SUMMA…
View article: Glycolysis Inhibition Functionally Reprograms T Follicular Helper Cells and Reverses Lupus
Glycolysis Inhibition Functionally Reprograms T Follicular Helper Cells and Reverses Lupus Open
View article: A deep unrolled neural network for real-time MRI-guided brain intervention
A deep unrolled neural network for real-time MRI-guided brain intervention Open
Accurate navigation and targeting are critical for neurological interventions including biopsy and deep brain stimulation. Real-time image guidance further improves surgical planning and MRI is ideally suited for both pre- and intra-operat…
View article: Meet the authors: Ying Lu, Donghoon Lee, and Yanan Zhu
Meet the authors: Ying Lu, Donghoon Lee, and Yanan Zhu Open
View article: Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts"
Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" Open
Supplementary information (figures and tables) for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" by Ya-Nan Zhu, Fan Pan, Xiao-Wen Gan, Yun Liu, Wang-Sheng Wan…
View article: Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts"
Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" Open
Supplementary information (figures and tables) for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" by Ya-Nan Zhu, Fan Pan, Xiao-Wen Gan, Yun Liu, Wang-Sheng Wan…
View article: Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts"
Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" Open
Supplementary information (figures and tables) for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" by Ya-Nan Zhu, Fan Pan, Xiao-Wen Gan, Yun Liu, Wang-Sheng Wan…
View article: Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts"
Supplementary information for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" Open
Supplementary information (figures and tables) for "Role of DNMT1 and C/EBPα in the regulation CYP11A1 expression during syncytialization of human placental trophoblasts" by Ya-Nan Zhu, Fan Pan, Xiao-Wen Gan, Yun Liu, Wang-Sheng Wan…
View article: Cigarette smoking induces the activation of RIP2/caspase-12/NF-<i>κ</i>B axis in oral squamous cell carcinoma
Cigarette smoking induces the activation of RIP2/caspase-12/NF-<i>κ</i>B axis in oral squamous cell carcinoma Open
Cigarette smoking is one of the major risk factors for the occurrence and progression of oral squamous cell carcinoma (OSCC). Receptor-interacting protein 2 (RIP2) has been involved in mucosal immunity and homeostasis via a positive regula…
View article: FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia
FLT3LG and IFITM3P6 consolidate T cell activity in the bone marrow microenvironment and are prognostic factors in acute myelocytic leukemia Open
Acute myelocytic leukemia (AML) is a malignancy of the stem cell precursors of the myeloid lineage. CD4+ and CD8+ T cells play pivotal roles in influencing AML progression but are functionally suppressed in the bone marrow microenvironment…
View article: Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages
Card9 protects sepsis by regulating Ripk2-mediated activation of NLRP3 inflammasome in macrophages Open
View article: Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth
Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth Open
View article: Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition
Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition Open
Background The human amnion is an intrauterine tissue which is involved in the initiation of parturition. In-depth understanding of gene expression signatures of individual cell types in the amnion with respect to membrane rupture at partu…
View article: The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth
The Bradykinin System Contributes to the Regulation of Prostaglandin-Endoperoxide Synthase 2 Expression in Human Amnion Fibroblasts: Implications for Term and Preterm Birth Open
Background Bradykinin (BK) and its biologically active metabolite des-Arg9 bradykinin (DABK) play a pivotal role in inflammation. Since chorioamnionitis is the leading cause of preterm birth and prostaglandin E2 (PGE2) derived from the amn…
View article: Card9 Protects Fungal Peritonitis Through Regulating Malt1-Mediated Activation of Autophagy in Macrophage
Card9 Protects Fungal Peritonitis Through Regulating Malt1-Mediated Activation of Autophagy in Macrophage Open
View article: Additional file 2 of Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition
Additional file 2 of Single cell transcriptomic analysis of human amnion identifies cell-specific signatures associated with membrane rupture and parturition Open
Additional file 2: Dataset 1. DEGs in epithelial cells between TL_P and TNL_P groups. Dataset 2. DEGs in epithelial cells between TL_P and TL_D groups. Dataset 3. DEGs in fibroblast cells between TL_P and TNL_P groups. Dataset 4. DEGs in f…