Lingyuan Yang
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View article: Therapeutic efficacy of a synthetic brain-targeted H 2 S donor cross-linked nanomicells in ASD rats via aerobic glycolysis
Therapeutic efficacy of a synthetic brain-targeted H 2 S donor cross-linked nanomicells in ASD rats via aerobic glycolysis Open
Autism spectrum disorder (ASD) presents cognitive and social deficits with a lacking brain-targeted medication landscape, notably in nanomedicine. Here, we introduce a novel brain-targeted H2S donor cross-linked nanomicelles named mannose-…
View article: Effects of High-Concentrate-Induced SARA on Antioxidant Capacity, Immune Levels and Rumen Microbiota and Function in Goats
Effects of High-Concentrate-Induced SARA on Antioxidant Capacity, Immune Levels and Rumen Microbiota and Function in Goats Open
This study aims to explore the antioxidant, immune, and enzyme metabolism aspects in goats experiencing subacute ruminal acidosis (SARA). Furthermore, we seek to elucidate the relationship between the symbiotic microbiota of goats and thei…
View article: Transplantation of fecal microbiota from different breeds improved intestinal barrier condition and modulated ileal microflora of recipient pigs
Transplantation of fecal microbiota from different breeds improved intestinal barrier condition and modulated ileal microflora of recipient pigs Open
In this study, we investigated the effects of transplanting Ningxiang pig fecal bacteria on the ileum microflora and intestinal barrier of Duroc × Landrace × Large White (DLY) pigs. Thirty-two DLY pigs at 90-d-old were equally assigned to …
View article: Effects of Non-Protein Nitrogen Sources on In Vitro Rumen Fermentation Characteristics and Microbial Diversity
Effects of Non-Protein Nitrogen Sources on In Vitro Rumen Fermentation Characteristics and Microbial Diversity Open
Here, the effects of non-protein nitrogen sources on fermentation parameters and microbial diversity were explored using three fistula goats as rumen fluid donors. The experiments involved six fermenters in a replicated 3 × 3 Latin square …
View article: Oral administration of<i>Lactobacillus delbrueckii</i>enhances intestinal immunity through inducing dendritic cell activation in suckling piglets
Oral administration of<i>Lactobacillus delbrueckii</i>enhances intestinal immunity through inducing dendritic cell activation in suckling piglets Open
Lactobacillus delbrueckii (LAB) modulates intestinal immunity through inducing DC maturation and activation, which is related to activation of the NF-κB and MAPK signaling pathways.
View article: Alterations of endotoxin distribution across different biofluids and relevant inflammatory responses by supplementing L-theanine in dairy cows during heat stress
Alterations of endotoxin distribution across different biofluids and relevant inflammatory responses by supplementing L-theanine in dairy cows during heat stress Open
The present trial was performed to reveal the regulatory effects of L-theanine on the levels of lipopolysaccharide (LPS) endotoxin within different biofluids, as well as relevant inflammatory responses of dairy cattle under heat stress con…
View article: Effects of Dietary Supplementation of Lactobacillus delbrueckii on Gut Microbiome and Intestinal Morphology in Weaned Piglets
Effects of Dietary Supplementation of Lactobacillus delbrueckii on Gut Microbiome and Intestinal Morphology in Weaned Piglets Open
Lactobacillus delbrueckii is a Gram-positive bacterium mostly used in the dairy industry for yogurt and cheese. The present study was designed to evaluate the effects of Lactobacillus delbrueckii on serum biochemical parameters, intestinal…
View article: Lactobacillus delbrueckii Protected Intestinal Integrity, Alleviated Intestinal Oxidative Damage, and Activated Toll-Like Receptor–Bruton’s Tyrosine Kinase–Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Weaned Piglets Challenged with Lipopolysaccharide
Lactobacillus delbrueckii Protected Intestinal Integrity, Alleviated Intestinal Oxidative Damage, and Activated Toll-Like Receptor–Bruton’s Tyrosine Kinase–Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Weaned Piglets Challenged with Lipopolysaccharide Open
Oxidative stress is increasingly being recognized as a player in the pathogenesis of intestinal pathologies, and probiotics are becoming an attractive means of addressing it. The present study investigated the effects of dietary supplement…
View article: Natural Polyphenols as Targeted Modulators in Colon Cancer: Molecular Mechanisms and Applications
Natural Polyphenols as Targeted Modulators in Colon Cancer: Molecular Mechanisms and Applications Open
Colon cancer commonly develops from long-term chronic inflammation in the intestine and seriously threatens human health. Natural polyphenols have been valued as a crucial regulator of nutrient metabolism and metabolic diseases, owing to t…
View article: The Associated Regulatory Mechanisms of Zinc Lactate in Redox Balance and Mitochondrial Function of Intestinal Porcine Epithelial Cells
The Associated Regulatory Mechanisms of Zinc Lactate in Redox Balance and Mitochondrial Function of Intestinal Porcine Epithelial Cells Open
Zinc lactate (ZnLA) is a new organic zinc salt which has antioxidant properties in mammals and can improve intestinal function. This study explored the effects of ZnLA and ZnSO4 on cell proliferation, Zn transport, antioxidant capacity, mi…
View article: Effects of Combined Supplementation of Conjugated Linoleic Acid, Methionine Chromium, Betaine, and Cysteamine on Meat Tenderness of Rats
Effects of Combined Supplementation of Conjugated Linoleic Acid, Methionine Chromium, Betaine, and Cysteamine on Meat Tenderness of Rats Open
A systemic design was carried out to investigate the optimal combination of BET, Met‐Cr, CLA, and CS for improving the meat tenderness in rats. A total of 104 six‐week old male Sprague‐Dawley rats were randomly assigned to 13 treatments wi…
View article: Oral Administration of <i>Lactobacillus delbrueckii</i> during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model
Oral Administration of <i>Lactobacillus delbrueckii</i> during the Suckling Phase Improves Antioxidant Activities and Immune Responses after the Weaning Event in a Piglet Model Open
Early colonization in the gut by probiotics influences the progressive development and maturity of antioxidant and immune system functionality in the future. This study investigated the impact of orally administrated Lactobacillus delbruec…