Sung‐Eun Lee
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View article: Comparative efficacy of TBI-based vs. non-TBI reduced toxicity conditioning regimens in adult ALL undergoing allogeneic HCT in CR1: Improved outcomes with TBI-based RTC and ATG/ptcy combination
Comparative efficacy of TBI-based vs. non-TBI reduced toxicity conditioning regimens in adult ALL undergoing allogeneic HCT in CR1: Improved outcomes with TBI-based RTC and ATG/ptcy combination Open
Background: The optimal conditioning regimen for adult patients with acute lymphoblastic leukemia (ALL) undergoing allogeneic hematopoietic cell transplantation (allo-HCT) remains controversial, particularly regarding the role of total bod…
View article: Comparative Analysis of DCIR and SOH in Field-Deployed ESS Considering Thermal Non-Uniformity Using Linear Regression
Comparative Analysis of DCIR and SOH in Field-Deployed ESS Considering Thermal Non-Uniformity Using Linear Regression Open
Large-scale lithium-ion energy storage systems (ESSs) are indispensable for renewable energy integration and grid support, yet ensuring long-term reliability under field conditions remains challenging. This study investigates degradation t…
View article: Biologically safe restoration of heavy metal-contaminated soils through plant-microbe synergy
Biologically safe restoration of heavy metal-contaminated soils through plant-microbe synergy Open
Abandoned mines have created extensive idle areas contaminated with heavy metals (HMs). Conventional remediation methods are often costly, environmentally disruptive, and pose risks to human health. As a sustainable alternative, a biologic…
View article: Partial Deletion of the Carboxyl‐Terminal Signal Sequence of the Cellular Prion Protein Alters Protein Expression via Endoplasmic Reticulum–Associated Degradation
Partial Deletion of the Carboxyl‐Terminal Signal Sequence of the Cellular Prion Protein Alters Protein Expression via Endoplasmic Reticulum–Associated Degradation Open
Cellular prion protein (PrP C ) is a glycoprotein tethered to the plasma membrane via a GPI‐anchor, and it plays a crucial role in prion diseases by undergoing conformational change to PrP Sc . To generate a knock‐in (KI) mouse model expre…
View article: The Effects of Caregiver-implemented Interventions on Generalization and Maintenance of the Acquisition of Social-Communication Skills in Children with Developmental Disabilities
The Effects of Caregiver-implemented Interventions on Generalization and Maintenance of the Acquisition of Social-Communication Skills in Children with Developmental Disabilities Open
This study systematically examined the effects of parent-implemented interventions on the generalization and maintenance of social communication skills in children with developmental disabilities. Single-case design studies conducted in So…
View article: Assessment of dry-fogged hydrogen peroxide as an “untact” room disinfection automation system for rapid terminal decontamination of a single isolation room in a healthcare institution
Assessment of dry-fogged hydrogen peroxide as an “untact” room disinfection automation system for rapid terminal decontamination of a single isolation room in a healthcare institution Open
Background This study evaluates the efficacy of dry-fogged hydrogen peroxide (dHP) as an “untact” room disinfection automation system (URDAS) for rapid terminal room decontamination. Methods This prospective study was conducted at a univer…
View article: Plumbagin, a natural derivative of 1,4-naphthoquinone, induces cyclopic phenomenon via increased apoptosis and ROS generation in the early stage of zebrafish embryos
Plumbagin, a natural derivative of 1,4-naphthoquinone, induces cyclopic phenomenon via increased apoptosis and ROS generation in the early stage of zebrafish embryos Open
Plumbagin (PL; 5-hydroxy-2-methyl-1,4-naphthoquinone) is an analogue of juglone (JG) with additional methylation on carbon 2. It has been found in fungi, insects, and plants, especially Malaysian persimmons, and plants containing PL are gl…
View article: Targeted Local Delivery via Fiber‐Embedded Flexible Microchannels Integrated with Film‐Based Implantable Probes
Targeted Local Delivery via Fiber‐Embedded Flexible Microchannels Integrated with Film‐Based Implantable Probes Open
This study presents the development of a fiber‐embedded drug‐delivery channel for implantable microprobe applications, marking the first functional drug delivery system based on flexible liquid crystal polymer (LCP) probes. The innovative …
View article: Stereoisomeric developmental toxicity of orysastrobin and its isomeric metabolite in zebrafish (Danio rerio) embryos: Cardiac abnormal development by orysastrobin
Stereoisomeric developmental toxicity of orysastrobin and its isomeric metabolite in zebrafish (Danio rerio) embryos: Cardiac abnormal development by orysastrobin Open
Orysastrobin (OSB), a strobilurin fungicide, inhibits the normal redox reactions of cytochrome bc1 at the Qo site of target phytopathogenic fungal species. Its frequent detection and high concentrations in natural wetlands and rivers have …
View article: Enantioselective toxicity of (S)-amlodipine towards zebrafish embryos: Abnormal ocular development, cardiac dysfunction, and malformed intersegmental vessels
Enantioselective toxicity of (S)-amlodipine towards zebrafish embryos: Abnormal ocular development, cardiac dysfunction, and malformed intersegmental vessels Open
Amlodipine (AM), widely used for the treatment of hypertension and angina, consists of two enantiomers: (S)-AM and (R)-AM. The extensive use of this medication has raised concerns regarding environmental contamination, but the enantioselec…
View article: Long-term clinical outcome of a weekly 2-chlorodeoxyadenosine regimen in treatment-naïve patients with hairy cell leukemia
Long-term clinical outcome of a weekly 2-chlorodeoxyadenosine regimen in treatment-naïve patients with hairy cell leukemia Open
Hairy cell leukemia (HCL) has a favorable clinical outcome with appropriate treatment; however, further research is needed on managing patients with relapsed or refractory disease and the risk of infection during prolonged periods. This st…
View article: Exploring Multimodal Perception in Large Language Models Through Perceptual Strength Ratings
Exploring Multimodal Perception in Large Language Models Through Perceptual Strength Ratings Open
This study investigated whether multimodal large language models can achieve human-like sensory grounding by examining their ability to capture perceptual strength ratings across sensory modalities. We explored how model characteristics (s…
View article: Proteomic evaluation of pathways associated with phosphine-induced mitochondrial dysfunction and resistance mechanisms in Tribolium castaneum against phosphine fumigation: Whole and partial proteome identification
Proteomic evaluation of pathways associated with phosphine-induced mitochondrial dysfunction and resistance mechanisms in Tribolium castaneum against phosphine fumigation: Whole and partial proteome identification Open
Phosphine (PH3) fumigation is widely used to control insect pests in stored products globally. However, intensive PH3 use has led to the emergence of significant resistance in target insects. To address this issue, this study investigated …
View article: Engineering Nicotiana benthamiana for chrysoeriol production using synthetic biology approaches
Engineering Nicotiana benthamiana for chrysoeriol production using synthetic biology approaches Open
Flavonoids are prevalent plant secondary metabolites with a broad range of biological activities. Their antioxidant, anti-inflammatory, and anti-cancer activities make flavonoids widely useful in a variety of industries, including the phar…
View article: Single-Cell RNA Sequencing Elucidates Cellular Origin and Heterogeneity in Acute Myeloid Leukemia
Single-Cell RNA Sequencing Elucidates Cellular Origin and Heterogeneity in Acute Myeloid Leukemia Open
Introduction: Acute myeloid leukemia (AML) is a heterogeneous malignancy arising from hematopoietic stem and progenitor cells (HSPCs) that acquire genetic abnormalities during hematopoiesis. Understanding the heterogeneous nature of AML is…
View article: Central Role of Hypothalamic Circuits for Acupuncture's Anti‐Parkinsonian Effects (Adv. Sci. 43/2024)
Central Role of Hypothalamic Circuits for Acupuncture's Anti‐Parkinsonian Effects (Adv. Sci. 43/2024) Open
Neurobiology of Acupuncture The neurobiological mechanisms of acupuncture, a traditional East Asian therapy, has remained elusive for millennia despite of its known therapeutic efficacy. Min‐Ho Nam, Hi‐Joon Park and their colleagues reveal…
View article: Central Role of Hypothalamic Circuits for Acupuncture's Anti‐Parkinsonian Effects
Central Role of Hypothalamic Circuits for Acupuncture's Anti‐Parkinsonian Effects Open
Despite clinical data stretching over millennia, the neurobiological basis of the effectiveness of acupuncture in treating diseases of the central nervous system has remained elusive. Here, using an established model of acupuncture treatme…
View article: The Antifungal and Inhibitory Effects of Massoia Essential Oil and C10 Massoia Lactone on Mycotoxin Production in Fusarium graminearum KACC 41047
The Antifungal and Inhibitory Effects of Massoia Essential Oil and C10 Massoia Lactone on Mycotoxin Production in Fusarium graminearum KACC 41047 Open
In wheat and barley, Fusarium head blight is mainly caused by Fusarium graminearum, and its control is based on the agricultural practices of not leaving crop residues in the field, growing phytopathogenic fungi-resistant varieties, biolog…
View article: Single-cell transcriptome analysis of low-dose radiotherapy-mediated alleviation of LPS-induced acute lung injury
Single-cell transcriptome analysis of low-dose radiotherapy-mediated alleviation of LPS-induced acute lung injury Open
Background Acute lung injury (ALI), a condition with a high incidence and mortality rate worldwide, is a type of acute respiratory failure characterized by infiltrative lesions in the lungs. Low-dose radiation therapy (LDRT), which uses le…
View article: Flavor identification and analysis of fermented soybean pastes
Flavor identification and analysis of fermented soybean pastes Open
Soybean paste is a staple food used to make doenjang (DE), cheonggukjang (CGJ), and miso (MI). In this study, solid-phase microextraction followed by gas chromatography-mass spectrometry was used to identify volatile components in DE, CGJ,…
View article: Exploring empathic engagement in immersive media: An EEG study on mu rhythm suppression in VR
Exploring empathic engagement in immersive media: An EEG study on mu rhythm suppression in VR Open
This study investigates the influence of immersive media, particularly Virtual Reality (VR), on empathic responses, in comparison to traditional television (TV), using electroencephalography (EEG). We employed mu rhythm suppression as a me…
View article: Developmental Toxicity of C10 Massoia Lactone, the Main Constituent of Cryptocarya massoia, on Zebrafish (Danio rerio) Embryos
Developmental Toxicity of C10 Massoia Lactone, the Main Constituent of Cryptocarya massoia, on Zebrafish (Danio rerio) Embryos Open
C10 massoia lactone (C10) is the main component of massoia essential oil derived from Cryptocarya massoia plant bark, which is used as natural flavoring agent of “generally recognized as safe” status. In this study, the developmental toxic…
View article: Development of Ethyl Formate Disinfestation Treatment Methods for the Prevention of the Introduction and Establishment of Exotic Insect Pests in Greenhouse Cultivation
Development of Ethyl Formate Disinfestation Treatment Methods for the Prevention of the Introduction and Establishment of Exotic Insect Pests in Greenhouse Cultivation Open
Globalization has increased international trade and caused an annual increase in the number of non-native insect pest species found in quarantine sites in Korea. Since over 80% of Korean farms use greenhouses with internal conditions condu…