Yanglei Yi
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Liquiritigenin ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function, reducing endoplasmic reticulum stress and modulating gut microbiota Open
Inflammatory bowel disease remains a high recurrence rate and broad populations all over the world. Liquiritigenin isolated from licorice possess anti-inflammatory and antioxidative activities, suggesting its potential of treating ulcerati…
Targeted discovery of gut microbiome-remodeling compounds for the treatment of systemic inflammatory response syndrome Open
Systemic inflammatory response syndrome (SIRS) is a severe inflammatory response that can lead to organ dysfunction and death. Modulating the gut microbiome is a promising therapeutic approach for managing SIRS. This study assesses the the…
Enhancing the antioxidant capacity and quality attributes of fermented goat milk through the synergistic action of Limosilactobacillus fermentum WXZ 2-1 with a starter culture Open
This study evaluated 75 strains of lactic acid bacteria (LAB) isolated from traditional dairy products in western China for their probiotic properties. Among them, Limosilactobacillus fermentum WXZ 2-1, Lactiplantibacillus plantarum TXZ 2-…
Dietary Lactiplantibacillus plantarum KX041 attenuates colitis-associated tumorigenesis and modulates gut microbiota Open
Colorectal cancer (CRC) is one of the most common cancers and supplementation of probiotics may be a promising intervention method. The present study aimed to investigate the anti-CRC effects of Lactiplantibacillus plantarum KX041 on a CRC…
Biosynthesis and Production of Class II Bacteriocins of Food-Associated Lactic Acid Bacteria Open
Bacteriocins are ribosomally synthesized peptides made by bacteria that inhibit the growth of similar or closely related bacterial strains. Class II bacteriocins are a class of bacteriocins that are heat-resistant and do not undergo extens…
Revealing the effects of Moringa oleifera Lam. leaves addition on Fuzhuan Brick Tea by metabolomic and microbiota analysis Open
The addition of Moringa oleifera Lam. leaves to the raw material for the co-fermentation was a promising way for the novel uses of Moringa oleifera Lam. leaves and the future trend of the Fuzhuan Brick Tea (FBT) industry. However, the effe…
Purification, characterization, and mode of action of a novel bacteriocin BM173 from Lactobacillus crustorum MN047 and its effect on biofilm formation of Escherichia coli and Staphylococcus aureus Open
There is an increasing demand for dairy products, but the presence of food-spoilage bacteria seriously affects the development of the dairy industry. Bacteriocins are considered to be a potential antibacterial or antibiofilm agent that can…
Cloning and characterization of low-temperature adapted GH5-CBM3 endo-cellulase from Bacillus subtilis 1AJ3 and their application in the saccharification of switchgrass and coffee grounds Open
Endocellulase is a key cellulase for cellulosic material pretreatment in the industry by hydrolyzing long cellulose chains into short chains. To investigate the endocellulase characteristics from Bacillus subtilis 1AJ3, and increase its pr…
Isolation of Thermostable Lignocellulosic Bacteria From Chicken Manure Compost and a M42 Family Endocellulase Cloning From Geobacillus thermodenitrificans Y7 Open
The composting ecosystem provides a potential resource for finding new microorganisms with the capability for cellulose degradation. In the present study, Congo red method was used for the isolating of thermostable lignocellulose-degrading…
Characterization of plant growth-promoting rhizobacteria from perennial ryegrass and genome mining of novel antimicrobial gene clusters Open
Background Plant growth-promoting rhizobacteria (PGPR) are good alternatives for chemical fertilizers and pesticides, which cause severe environmental problems worldwide. Even though many studies focus on PGPR, most of them are limited in …
Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics Open
Background Luman is a member of CREB3 (cAMP responsive element-binding) subfamily of the basic leucine-zipper (bZIP) transcription factors. It may play an important regulatory role during the decidualization process since Luman was highly …
Screening of cellulolytic bacteria from rotten wood of Qinling (China) for biomass degradation and cloning of cellulases from Bacillus methylotrophicus Open
Background Cellulosic biomass degradation still needs to be paid more attentions as bioenergy is the most likely to replace fossil energy in the future, and more evaluable cellulolytic bacteria isolation will lay a foundation for this file…
Additional file 4 of Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics Open
Additional file 4. List of differentially expressed genes enriched in different signal pathways. (Sheet 1, shLuman vs shNC at 48 h decidualization; Sheet 2, shLuman vs shNC at 72 h decidualization).
Additional file 3 of Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics Open
Additional file 3. Illumina RNA-Seq data of all significantly differentially expressed genes in different categories (Sheet 1, shLuman vs shNC at 0 h decidualization; Sheet 2, shLuman vs shNC at 48 h decidualization; Sheet 3, shLuman vs sh…
Cellulolytic Bacteria Screened from Qinling (China) for Biomass Degradation and Cellulases First Cloned from Bacillus methylotrophicus Open
Background Cellulosic biomass degradation still needed more studies while bioenergy is becoming mainly energy in future and more evaluate bacteria isolation laid a foundation of further study. Qinling Mountains have unique biodiversity, ac…
Exploring plant‐microbe interactions of the rhizobacteria <i>Bacillus subtilis</i> and <i>Bacillus mycoides</i> by use of the CRISPR‐Cas9 system Open
Summary Bacillus subtilis HS3 and Bacillus mycoides EC18 are two rhizosphere‐associated bacteria with plant growth‐promoting activity. The CRISPR‐Cas9 system was implemented to study various aspects of plant‐microbe interaction mechanisms …
Plant-Microbe Interaction: Transcriptional Response of <em>Bacillus Mycoides</em> to Potato Root Exudates Open
Beneficial plant-associated bacteria play an important role in promoting growth and preventing disease in plants. The application of plant growth-promoting rhizobacteria (PGPR) as biofertilizers or biocontrol agents has become an effective…
Bacillus mycoides: novel tools for studying the mechanisms of its interaction with plants Open
Plantengroei bevorderende rhizobacteriën (PBR) is een groep bacteriën die de wortels van de plant koloniseren en de plantengroei kunnen bevorderen. Inzicht in de moleculaire mechanismen van hoe planten en PBR naast elkaar kunnen bestaan …
Optimized fluorescent proteins for the rhizosphere‐associated bacterium <i>Bacillus mycoides</i> with endophytic and biocontrol agent potential Open
Summary Tracking of fluorescent protein (FP)‐labelled rhizobacteria is a key prerequisite to gain insights into plant‐bacteria interaction mechanisms. However, the performance of FPs mostly has to be optimized for the bacterial host and fo…
Comparative Transcriptomics of Bacillus mycoides Strains in Response to Potato-Root Exudates Reveals Different Genetic Adaptation of Endophytic and Soil Isolates Open
Plant root secreted compounds alter the gene expression of associated microorganisms by acting as signal molecules that either stimulate or repel the interaction with beneficial or harmful species, respectively. However, it is still unclea…
Development of an efficient electroporation method for rhizobacterial Bacillus mycoides strains Open
In order to develop a method for electroporation of environmental Bacillus mycoides strains, we optimized several conditions that affect the electroporation efficiency of this bacterium. By combining the optimized conditions, the electropo…
Knockdown of CREB3/Luman by shRNA in Mouse Granulosa Cells Results in Decreased Estradiol and Progesterone Synthesis and Promotes Cell Proliferation Open
Luman (also known as LZIP or CREB3) is a transcription factor and a member of the cAMP responsive element-binding (CREB) family proteins. Although Luman has been detected in apoptotic granulosa cells and disorganized atretic bodies, the ph…
Draft Genome Sequence of Bacillus mycoides M2E15, a Strain Isolated from the Endosphere of Potato Open
We present the draft genome sequence of Bacillus mycoides M2E15, a bacterium isolated from potato endosphere. Analysis of the 6.08-Mbp draft genome sequence identified 6,386 protein-encoding sequences, including potential plant growth prom…