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View article: An Artificial Intelligence Pipeline for Hepatocellular Carcinoma: From Data to Treatment Recommendations
An Artificial Intelligence Pipeline for Hepatocellular Carcinoma: From Data to Treatment Recommendations Open
Hepatocellular carcinoma (HCC) poses significant clinical challenges, including difficulties in early diagnosis and the complexity of treatment options. Artificial intelligence (AI) technologies are emerging as powerful tools to address th…
View article: Studies on the hybrid model and flow characteristics in vanadium redox flow battery
Studies on the hybrid model and flow characteristics in vanadium redox flow battery Open
To improve the operating efficiency of vanadium redox flow battery (VRB), this paper considers the effects of electrolyte flow rate and charge-discharge current on the VRB operation state. By coupling the equivalent loss model, the electro…
View article: Myocardial cGMP-PKG1α dysregulation contributes to VT pathogenesis in type II diabetes and metabolic syndrome
Myocardial cGMP-PKG1α dysregulation contributes to VT pathogenesis in type II diabetes and metabolic syndrome Open
Background Type-II diabetes (DMII) and metabolic syndrome increase ventricular arrhythmia and sudden cardiac death risk. Objectives To identify signaling mechanisms through which DMII and metabolic syndrome promote ventricular tachycardia …
View article: Friction and Wear Characteristics of Micro‐Arc Oxidation Coating on Ti6Al4V Alloy—A Review
Friction and Wear Characteristics of Micro‐Arc Oxidation Coating on Ti6Al4V Alloy—A Review Open
Ti6Al4V alloy is widely used in artificial joints, artificial bones, and dental implants due to its elastic modulus similar to that of bone, good biocompatibility and non‐cytotoxicity, low density, and excellent fatigue resistance. However…
View article: Fretting-corrosion mechanisms of Ti6Al4V against CoCrMo in simulated body fluid under various fretting states
Fretting-corrosion mechanisms of Ti6Al4V against CoCrMo in simulated body fluid under various fretting states Open
Ti6Al4V alloy–CoCrMo alloy pair is commonly applied for modular head–neck interfaces for artificial hip joint. Unfortunately, the fretting corrosion damage at this interface seriously restricts its lifespan. This work studied the fretting …
View article: TGF-β Promotes Hepatocellular Carcinoma Metastasis Through Through m6A Modification of PCDHGA9
TGF-β Promotes Hepatocellular Carcinoma Metastasis Through Through m6A Modification of PCDHGA9 Open
Objective: Hepatocellular carcinoma (HCC) is a highly lethal cancer with significant mortality, primarily attributed to metastasis. Although Protocadherin Gamma Subfamily A, 9 (PCDHGA9) has been identified as a tumor suppressor gene in can…
View article: Analysis of an Interface Crack between Piezoelectric Semiconductor Coating and Elastic Substrate Structure
Analysis of an Interface Crack between Piezoelectric Semiconductor Coating and Elastic Substrate Structure Open
Piezoelectric semiconductor materials possess a unique combination of piezoelectric and semiconductor effects, exhibiting multifaceted coupling properties such as electromechanical, acoustic, photoelectric, photovoltaic, thermal, and therm…
View article: Deep Cracking of Bulky Hydrocarbons into Light Products via Tandem Catalysis over Uniform Interconnected ZSM‐5@AlSBA‐15 Composites
Deep Cracking of Bulky Hydrocarbons into Light Products via Tandem Catalysis over Uniform Interconnected ZSM‐5@AlSBA‐15 Composites Open
Deep cracking of bulky hydrocarbons on zeolite‐containing catalysts into light products with high activity, desired selectivity, and long‐term stability is demanded but challenging. Herein, the efficient deep cracking of 1,3,5‐triisopropyl…
View article: The influence of social networking site use on adolescents' body dissatisfaction and its internal mechanism
The influence of social networking site use on adolescents' body dissatisfaction and its internal mechanism Open
摘要: 身体不满意在青少年群体中广泛存在, 社交网站使用被视为一种关键的影响因素。系统梳理社交网站使用影响青少年身体不满意的表现形式、作用路径及其中的调节因素, 对于预防和干预青少年身体不满意具有重要意义。社交网站使用的程度、形式、行为以及动机均可能对青少年的身体不满意产生影响。这种影响主要通过"外貌比较与理想身材内化" "自我客体化与身体监控" "外貌自我图式与外貌自我差异"三条路径发挥作用。此外, 这种影响会受到包括大五人格、自恋和完美主义的人格因素, 自我同情、自我概…
View article: [Three-dimensional reconstruction of femur based on Laplace operator and statistical shape model].
[Three-dimensional reconstruction of femur based on Laplace operator and statistical shape model]. Open
Reconstructing three-dimensional (3D) models from two-dimensional (2D) images is necessary for preoperative planning and the customization of joint prostheses. However, the traditional statistical modeling reconstruction shows a low accura…
View article: Study on the Cavitation Characteristics of Shroud Clearance in Prototype and Model of a Kaplan Turbine
Study on the Cavitation Characteristics of Shroud Clearance in Prototype and Model of a Kaplan Turbine Open
Model tests and model calculations are the most basic means currently available to study the characteristics of the axial-flow pumps and Kaplan turbines in a systematic manner. Large and medium-sized turbine units and axial-flow pumps must…
View article: A novel algorithm to efficiently calculate the impingement‐free range of motion of irregularly‐shaped total hip arthroplasty components
A novel algorithm to efficiently calculate the impingement‐free range of motion of irregularly‐shaped total hip arthroplasty components Open
There is great difficulty in quickly calculating the impingement‐free range of motion (IFROM) of hip components with complex shapes after total hip arthroplasty. We have established a new algorithm to investigate the effect of different sh…
View article: A preliminary experimental investigation on the biotribocorrosion of a metal-on-polyethylene hip prosthesis in a hip simulator
A preliminary experimental investigation on the biotribocorrosion of a metal-on-polyethylene hip prosthesis in a hip simulator Open
Corrosion at the taper/trunnion interface of total hip replacement (THR) often results in severe complications. However, the underlying mechanisms of biotribocorrosion at the taper/trunnion interface during the long-term walking gait cycle…
View article: Kinematic alignment versus mechanical alignment in total knee arthroplasty: An up-to-date meta-analysis
Kinematic alignment versus mechanical alignment in total knee arthroplasty: An up-to-date meta-analysis Open
Purpose The purpose of this meta-analysis was to compare the efficacy and imaging parameters of kinematic alignment (KA) and mechanical alignment (MA) in total knee arthroplasty (TKA) and to evaluate whether patients undergoing KA-TKA bene…
View article: Single-Cell Analyses of a Novel Mouse Urothelial Carcinoma Model Reveal a Role of Tumor-Associated Macrophages in Response to Anti-PD-1 Therapy
Single-Cell Analyses of a Novel Mouse Urothelial Carcinoma Model Reveal a Role of Tumor-Associated Macrophages in Response to Anti-PD-1 Therapy Open
Approximately 80% of patients with advanced bladder cancer do not respond to immune checkpoint inhibitor (ICI) immunotherapy. Therefore, there is an urgent unmet need to develop clinically relevant preclinical models so that factors govern…
View article: The crystal structure of 5,6-dichloro-2-(quinolin-8-yl)isoindoline-1,3-dione, C<sub>17</sub>H<sub>8</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>2</sub>
The crystal structure of 5,6-dichloro-2-(quinolin-8-yl)isoindoline-1,3-dione, C<sub>17</sub>H<sub>8</sub>Cl<sub>2</sub>N<sub>2</sub>O<sub>2</sub> Open
C 17 H 8 Cl 2 N 2 O 2 , triclinic, P 1 ‾ $\overline{1}$ (no. 2), a = 7.9032(2) Å, b = 9.0843(3) Å, c = 10.8051(2) Å, α = 85.2310(10)°, β = 85.0270(10)°, γ = 71.013(2)°, V = 729.54(3) Å 3 , Z = 2, R gt ( F ) = 0.0417, wR ref ( F 2 ) =…
View article: High Wear Resistance of Ultralow-wear Polyethylene With Different Molecular Weights Under Different Contact Pressure
High Wear Resistance of Ultralow-wear Polyethylene With Different Molecular Weights Under Different Contact Pressure Open
Ultralow-wear polyethylene (ULWPE), a type of polyethylene homocomposite with excellent wear resistance, has recently been reported, however its underlying wear mechanism has yet to be clarified. In the current study, three different molec…
View article: Robust Optical Frequency Comb Generation by Using a Three-Stage Optical Nonlinear Dynamic
Robust Optical Frequency Comb Generation by Using a Three-Stage Optical Nonlinear Dynamic Open
In this article, we propose and investigate a novel scheme to generate optical frequency combs (OFCs) by using a three-stage generator, which is based on optical injection–induced dynamics cascaded by subharmonic electro-optic modulation a…
View article: A review of the bio-tribology of medical devices
A review of the bio-tribology of medical devices Open
Numerous medical devices have been applied for the treatment or alleviation of various diseases. Tribological issues widely exist in those medical devices and play vital roles in determining their performance and service life. In this revi…
View article: Elastic response of anisotropic Gyroid cellular structures under compression: Parametric analysis
Elastic response of anisotropic Gyroid cellular structures under compression: Parametric analysis Open
Triply periodic minimal surface (TPMS) is identified as a suitable model for designing porous structures. Gyroid cellular structure (GCS) is the most widely studied type of TPMS structure. The majority of previous studies on GCS have focus…