Explanipedia

Circulating T lymphocyte subsets are associated clinical features and long-term prognosis in patients with hypertensive renal injury Open

Chi Xu, D. Liu, Zhihe Zhao, Feng Yu, Wei Liu , et al. · 2025

Aim Although numerous studies have demonstrated the key role of immune system in hypertensive end organ damage, much less is known regarding the alterations of circulating immune cells in hypertensive renal injury.In this study, we examine…

Developing machine learning‐driven acute kidney injury predictive models using non‐standard EMRs in resource‐limited settings Open

Shengwen Guo, Yuanhan Chen, Yu Kuang, Qin Zhang, Yanhua Wu , et al. · 2025

Background Acute Kidney Injury (AKI) remains a significant global health challenge, especially in resource‐limited settings. Most existing predictive models rely heavily on serum creatinine (SCr) levels and standardized electronic medical …

Dispersive-induced magnon blockade with a superconducting qubit Open

Zeng‐Xing Liu, Yanhua Wu, Jinghua Sun · 2025

We investigate the magnon blockade effect in a quantum magnonic system operating in the strong dispersive regime, where a superconducting qubit interacts dispersively with a magnonic mode in a yttrium-iron-garnet sphere.By solving the quan…

Identification of Two Novel Missense Variants in BNC1 in Han Chinese Patients With Non‐syndromic Premature Ovarian Insufficiency Open

Yuncheng Pan, Jitong Mo, Shuting Ren, Yifei Zhang, Feng Zhang , et al. · 2024

Two novel heterozygous missense mutations in BNC1 (NM_001717): c.1000A>G (p.Arg334Gly) and c.1535C>T (p.Pro512Leu) were identified through whole-exome sequencing in two Han Chinese POI patients, expanding the spectrum of BNC1 variants in n…

Sleep timing and the prevalence of hypertension in middle-aged and older populations: the sleep heart health study Open

Shuang G. Zhao, Juan Zhao, Suhua Wei, Wenjuan Wang, Yanhua Wu , et al. · 2024

Our findings identified a nonlinear association between sleep timing and hypertension. Individuals with both early and late sleep timing had a high prevalence of hypertension.

Pig-derived ECM-SIS provides a novel matrix gel for tumor modeling Open

Yanhua Wu, Hao Wang, Changbo Qu, Xuesong Deng, Na Li , et al. · 2024

The absence of effective extracellular matrix to mimic the natural tumor microenvironment remains a significant obstacle in cancer research. Matrigel, abundant in various biological matrix components, is limited in its application due to i…

Rare variants in GPR3 in POI patients: a case series with review of literature Open

Shuting Ren, Feng Zhang, Lingyue Shang, Xi Yang, Yuncheng Pan , et al. · 2023

HELQ as a DNA helicase: Its novel role in normal cell function and tumorigenesis (Review) Open

Nan Tang, Wei‐Lun Wen, Zhihe Liu, Xifeng Xiong, Yanhua Wu · 2023

Helicase POLQ‑like (HELQ or Hel308), is a highly conserved, 3'‑5' superfamily II DNA helicase that contributes to diverse DNA processes, including DNA repair, unwinding, and strand annealing. HELQ deficiency leads to subfertility, due to i…

A model for predicting postoperative persistent acute kidney injury (AKI) in AKI after cardiac surgery patients with normal baseline renal function Open

Yuanhan Chen, Zhiming Mo, Hong Chu, Penghua Hu, Wei Fan , et al. · 2023

Background Persistent acute kidney injury (AKI) after cardiac surgery is not uncommon and linked to poor outcomes. Hypothesis The purpose was to develop a model for predicting postoperative persistent AKI in patients with normal baseline r…

The role and implication of autophagy in cholangiocarcinoma Open

Hayat Khizar, Yufei Hu, Yanhua Wu, Jianfeng Yang · 2023

Identification of lncRNA expression profiles associated with ovarian development and ageing process in mice Open

Siyuan Chen, Zixue Zhou, Xi Yang, Yuncheng Pan, Renbin Liu , et al. · 2023

Long non-coding RNA (lncRNA) participates in various biological processes, however, neither the expression profile nor the biological role of lncRNAs in mammalian ovaries has been fully studied. In this work, the lncRNA transcriptomic anal…

Clinicopathological features and outcome in elderly patients with idiopathic membranous nephropathy Open

Jinxiu Liang, Wenke Hao, Fangxiao Xia, Zhi Zhao, Yanhua Wu , et al. · 2023

Idiopathic membranous nephropathy (IMN) is the leading cause of nephrotic syndrome in the elderly. The treatment of idiopathic membranous nephropathy is quite challenging due to the particularity of elderly patients. This study intends to …

Supplementary Data from Proapoptotic Function of Integrin β3 in Human Hepatocellular Carcinoma Cells Open

Yanhua Wu, Jie Zuo, Guoqing Ji, Hexige Saiyin, Xing Liu , et al. · 2023

Supplementary Data from Proapoptotic Function of Integrin β₃ in Human Hepatocellular Carcinoma Cells

Data from Proapoptotic Function of Integrin β3 in Human Hepatocellular Carcinoma Cells Open

Yanhua Wu, Jie Zuo, Guoqing Ji, Hexige Saiyin, Xing Liu , et al. · 2023

Purpose: This study evaluates the proapoptotic function of integrin β₃ in human hepatocellular carcinoma (HCC).Experimental Design: The expression of integrin β₃ in 67 HCC specimens paired with correspon…

Data from Proapoptotic Function of Integrin β3 in Human Hepatocellular Carcinoma Cells Open

Yanhua Wu, Jie Zuo, Guoqing Ji, Hexige Saiyin, Xing Liu , et al. · 2023

Purpose: This study evaluates the proapoptotic function of integrin β₃ in human hepatocellular carcinoma (HCC).Experimental Design: The expression of integrin β₃ in 67 HCC specimens paired with correspon…

Supplementary Data from Proapoptotic Function of Integrin β3 in Human Hepatocellular Carcinoma Cells Open

Yanhua Wu, Jie Zuo, Guoqing Ji, Hexige Saiyin, Xing Liu , et al. · 2023

Supplementary Data from Proapoptotic Function of Integrin β₃ in Human Hepatocellular Carcinoma Cells

Single-cell sequencing reveals peritoneal environment and insights into fibrosis in CAPD patients Open

Wenxue Hu, Guanglan Li, Wei Dong, Peng He, Wei Liu , et al. · 2023

Long-term peritoneal dialysis (PD) is associated with the development of peritoneal fibrosis (PF). Understanding the changes of immune environments and peritoneal mesothelial cells (PMCs) may lead to the discovery of mechanisms of PF. Ther…

Landscape of pathogenic mutations in premature ovarian insufficiency Open

Hanni Ke, Shuyan Tang, Ting Guo, Dong Hou, Xue Jiao , et al. · 2023

Premature ovarian insufficiency (POI) is a major cause of female infertility due to early loss of ovarian function. POI is a heterogeneous condition, and its molecular etiology is unclear. To identify genetic variants associated with POI, …

Self-Propelled Micromotors Based on Natural Pyrolusite for Dynamic Remediation of Organic Contaminated Soil Open

Yuchan Li, Yanhua Wu, Hong Wang · 2023

Additional file 1 of Rare variants in GPR3 in POI patients: a case series with review of literature Open

Shuting Ren, Feng Zhang, Lingyue Shang, Xi Yang, Yuncheng Pan , et al. · 2023

Additional file 1: Supplementary table 1. Filtering steps of two WES data processing. Supplementary table 2. Primers used for Sanger sequencing. Supplementary table 3. List of 101 known POI causative genes. Supplementary table 4. List of 9…

Gastric lymphoepithelial-like carcinoma presenting as a sub-mucosal mass: a case report and literature review. Open

Hayat Khizar, Yanhua Wu, Yufei Hu, Xiaofeng Zhang, Jianfeng Yang · 2023

Cases of gastric LELC are rare, and clinicians need to improve their understanding of the disease to avoid misdiagnosis. The etiology and pathogenesis of this disease need further investigation.

Aberrant NAD synthetic flux in podocytes under diabetic conditions and effects of indoleamine 2,3-dioxygenase on promoting de novo NAD synthesis Open

Yuhua Zhang, Xingchen Zhao, Cuili Li, Yan Yang, Luan Li , et al. · 2022

Nicotinamide adenine dinucleotide (NAD) is an essential coenzyme in the kidney. The first step in de novo NAD synthesis is regulated by indoleamine 2,3-dioxygenase (IDO), a tryptophan-catabolizing enzyme. Here, we investigated NAD syntheti…

Effect of potassium rate on yield, potassium uptake and canopy radiation interception of direct-seeded winter canola Open

Rui Wang, Ahui Liu, Xiaolei Chen, Yanhua Wu, Wenli Peng · 2022

Direct seeded canola (Brassica napus L.) has become increasingly popular in Chinaâs key canola-producing regions. The studies on the K response of direct-seeded canola performance are limited. This research aimed to investigate the K uti…

The value of the ACEF II score in Chinese patients with elective and non-elective cardiac surgery Open

Zhiming Mo, Penghua Hu, Zhiyong Xie, Yanhua Wu, Zhilian Li , et al. · 2022

Corrigendum: Long non-coding RNAs as molecular biomarkers in cholangiocarcinoma Open

Yanhua Wu, Khizar Hayat, Yufei Hu, Jianfeng Yang · 2022

[This corrects the article DOI: 10.3389/fcell.2022.890605.].

PTEN Expression Was Significantly Associated with PD-L1 Score but Not with EBV Infection in Gastric Cancer Open

Donghui Cao, Tongrong Su, Yanhua Wu, Zhifang Jia, Yingli Fu , et al. · 2022

The above results suggested that PTEN expression was a useful marker in gastric carcinogenesis and progression and in the selection of immunotherapy-based treatments for GC patients.

Genome-Wide Comparative Analysis of Transposable Elements by Matrix-TE Method Revealed Indica and Japonica Rice Evolution Open

Zhiguo Wu, Wei Xi, Zixuan Han, Yanhua Wu, Yongzhuo Guan , et al. · 2022

Transposons (TEs) are known to change the gene expression and function, and subsequently cause plant speciation and evolution. Nevertheless, efficient and new approaches are required to investigate the role of TEs in the plant genome struc…

Long Non-Coding RNAs as Molecular Biomarkers in Cholangiocarcinoma Open

Yanhua Wu, Hayat Khizar, Yufei Hu, Jianfeng Yang · 2022

Cholangiocarcinoma (CCA) is a biliary system cancer that has the characteristics of strong invasiveness, poor prognosis, and few therapy choices. Furthermore, the absence of precise biomarkers for early identification and prognosis makes i…

HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice Open

Qi‐Qi Wang, Qing Chen, Yixin Zhang, Xue Zhang, Chunyu Liu , et al. · 2022

Premature ovarian insufficiency (POI) is a severe female reproductive disorder that affects 1%−2% of women in general populations.1 The analysis of familial POI implies that genetic aberrations strongly influence the onset of POI.2 However…

Soil Decontamination by Natural Minerals Via Fenton-Like Reactions: A Comparison Study of Chalcopyrite and Pyrite Open

Yanhua Wu, Yuchan Li, Hong Wang · 2022

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