Yanjing Guo
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View article: Case Report: Gefitinib in EGFR 19del recurrent aggressive fibromatosis
Case Report: Gefitinib in EGFR 19del recurrent aggressive fibromatosis Open
We present the first case of a male patient with an epidermal growth factor receptor (EGFR) 19del mutation who was diagnosed with intra-abdominal aggressive fibromatosis and familial adenomatous polyposis. We assessed the clinical response…
View article: Fabrication of Biocompatible Transdermal Nanofibrous Patch for Localized Delivery of Lidocaine and Rosemary Oil to Improve Effective Management of Lymphoma Pain and Nursing Care
Fabrication of Biocompatible Transdermal Nanofibrous Patch for Localized Delivery of Lidocaine and Rosemary Oil to Improve Effective Management of Lymphoma Pain and Nursing Care Open
Background The primary goal of the current investigation is to fabricate a transdermal NFs patch-based drug delivery system using Poly-N-Vinyl Caprolactam (PNVCL) blended with sodium alginate to prepared transdermal nanofibrous patch for l…
View article: Exploring Independent Effects of Follicle-Stimulating Hormone <em>In Vivo</em> in a Mouse Model
Exploring Independent Effects of Follicle-Stimulating Hormone <em>In Vivo</em> in a Mouse Model Open
During the transition from a reproductive to a nonreproductive phase (menopause), many women experience significant physiological and pathological changes, including decreased bone mass, increased blood lipids, and increased visceral adipo…
View article: Data from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Data from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Cancer stem-like cells (CSC) drive cancer progression and recurrence. Self-renewal expansion of CSC is achieved through symmetric cell division, yet how external stimuli affect intracellular regulatory programs of CSC division modes and st…
View article: Supplementary Table 2 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Table 2 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Table 2: Primer sequences used in the qRT-PCR experiment
View article: Supplementary Data from Numb<sup>−/low</sup> Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling
Supplementary Data from Numb<sup>−/low</sup> Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling Open
Supplementary Mehods, Materials, figures and tables Figure S1. Immunofluorescent staining of Numb in PCa tissues. Figure S2. Classical Wnt signaling was not affected by Numb in PCa cells. Figure S3. The mRNA levels of Hes1 and GLI1 negativ…
View article: Data from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Data from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Cancer stem-like cells (CSC) drive cancer progression and recurrence. Self-renewal expansion of CSC is achieved through symmetric cell division, yet how external stimuli affect intracellular regulatory programs of CSC division modes and st…
View article: Supplementary Fig 4 related to Fig 4 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 4 related to Fig 4 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 4 related to Fig 4: hTERThigh PCa cells exhibit three distinct cell division modes in a Numb-dsRed segregation context
View article: Supplementary Fig 1 related to Fig 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 1 related to Fig 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 1 related to Fig 1: hTERT expression in PCa specimens and FACS sorted hTERT-/low and hTERThigh PCa cells
View article: Supplementary Materials and Methods from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Materials and Methods from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Materials and Methods
View article: Supplementary Fig 5 related to Fig 5 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 5 related to Fig 5 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 5 related to Fig 5: The Effects of WNT ligands and WNT inhibitors on SCD I, SCD II and ACD ratio of hTERThigh LNCaP cells
View article: Supplementary Table 2 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Table 2 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Table 2: Primer sequences used in the qRT-PCR experiment
View article: Supplementary Fig 4 related to Fig 4 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 4 related to Fig 4 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 4 related to Fig 4: hTERThigh PCa cells exhibit three distinct cell division modes in a Numb-dsRed segregation context
View article: Supplementary Fig 1 related to Fig 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 1 related to Fig 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 1 related to Fig 1: hTERT expression in PCa specimens and FACS sorted hTERT-/low and hTERThigh PCa cells
View article: Supplementary Fig 2 related to Fig 2 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 2 related to Fig 2 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 2 related to Fig 2: hTERT promotes xenograft tumor growth and EMT of PCa cells
View article: Supplementary Fig 7 related to Fig 7 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 7 related to Fig 7 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 7 related to Fig 7: Validation of beta-catenin knockdown efficiency in PCa cells
View article: Supplementary Fig 8 working model from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 8 working model from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 8 working model: Schematic model of hTERThigh PCSCs cell division modes modulated by WNT/beta-catenin
View article: hTERT-/low and hTERThigh PCa cell division modes from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
hTERT-/low and hTERThigh PCa cell division modes from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
hTERT-/low and hTERThigh PCa cell division modes from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells
View article: Supplementary Table 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Table 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Table 1: Antibodies and proteins used in the present study
View article: Supplementary Fig 3 related to Fig 3 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 3 related to Fig 3 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 3 related to Fig 3: hTERT enhances the holoclone formation capacity of PCa cells
View article: Data from Numb<sup>−/low</sup> Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling
Data from Numb<sup>−/low</sup> Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling Open
Purpose: To elucidate the role and molecular mechanism of Numb in prostate cancer and the functional contribution of Numb−/low prostate cancer cells in castration resistance.Experimental Design: The expression of N…
View article: Supplementary Fig 6 related to Fig 6 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 6 related to Fig 6 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 6 related to Fig 6: PCa tissues with elevated WNT signaling activation express higher level of hTERT
View article: Data from Numb<sup>−/low</sup> Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling
Data from Numb<sup>−/low</sup> Enriches a Castration-Resistant Prostate Cancer Cell Subpopulation Associated with Enhanced Notch and Hedgehog Signaling Open
Purpose: To elucidate the role and molecular mechanism of Numb in prostate cancer and the functional contribution of Numb−/low prostate cancer cells in castration resistance.Experimental Design: The expression of N…
View article: Supplementary Fig 6 related to Fig 6 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 6 related to Fig 6 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 6 related to Fig 6: PCa tissues with elevated WNT signaling activation express higher level of hTERT
View article: Supplementary Fig 5 related to Fig 5 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 5 related to Fig 5 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 5 related to Fig 5: The Effects of WNT ligands and WNT inhibitors on SCD I, SCD II and ACD ratio of hTERThigh LNCaP cells
View article: Supplementary Fig 8 working model from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 8 working model from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 8 working model: Schematic model of hTERThigh PCSCs cell division modes modulated by WNT/beta-catenin
View article: Supplementary Materials and Methods from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Materials and Methods from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Materials and Methods
View article: Supplementary Table 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Table 1 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Table 1: Antibodies and proteins used in the present study
View article: Supplementary Fig 7 related to Fig 7 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
Supplementary Fig 7 related to Fig 7 from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
Supplementary Fig 7 related to Fig 7: Validation of beta-catenin knockdown efficiency in PCa cells
View article: hTERT-/low and hTERThigh PCa cell division modes from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells
hTERT-/low and hTERThigh PCa cell division modes from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERT<sup>high</sup> Prostate Cancer Stem Cells Open
hTERT-/low and hTERThigh PCa cell division modes from WNT/β-Catenin Directs Self-Renewal Symmetric Cell Division of hTERThigh Prostate Cancer Stem Cells