Yannick Waumans
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View article: Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy
Automated tumor immunophenotyping predicts clinical benefit from anti-PD-L1 immunotherapy Open
Background Cancer immunotherapy has transformed the clinical approach to patients with malignancies as profound benefits can be seen in a subset of patients. To identify this subset, biomarker analyses increasingly focus on phenotypic and …
View article: Stromal marker fibroblast activation protein drives outcome in T1 non-muscle invasive bladder cancer
Stromal marker fibroblast activation protein drives outcome in T1 non-muscle invasive bladder cancer Open
Fibroblast activation protein-α (FAP) is a transmembrane peptidase and a surrogate marker for cancer-associated fibroblasts (CAFs). FAP has been linked to worse prognosis and therapy resistance in several cancers. We hypothesised that FAP …