Yansen Chen
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Comparing the genetic architecture of energy balance predicted by mid-infrared spectrometry, a novel energy deficiency score, and several biomarkers Open
Negative energy balance (NEB) during early lactation is a critical physiological challenge in high-producing dairy cows, affecting both their health and production performance. The objectives of this study were: (1) to compare the genetic …
Using single-step genome-wide association analyses to compare predicted negative energy balance and a novel energy deficiency score in early-lactation Holstein cows Open
This study aimed to compare the genetic architectures of logit-transformed predicted negative energy balance (LPNEB) and a novel logit-transformed energy deficiency score (LEDS) as 2 mid-infrared-derived proxies of negative energy balance …
View article: Recorded responses of Four Tall buildings in South China to the M 7.9 Myanmar Earthquake on March 28, 2025
Recorded responses of Four Tall buildings in South China to the M 7.9 Myanmar Earthquake on March 28, 2025 Open
This paper reports the recorded structural responses of four 170 m–320 m tall buildings in China to the mainshock of the M 7.9 Myanmar earthquake on March 28, 2025. The buildings are located approximately 1 200 km–2 000 km away from the e…
Exploring the relationship between predicted negative energy balance and its biomarkers of Holstein cows in first-parity early lactation Open
The negative energy balance (NEB) state in dairy cows is a critical factor affecting health, reproduction, and production, particularly during early lactation. Multiple blood and milk biomarkers change when dairy cows are in the NEB state.…
Dynamic factor analysis of high-dimensional recurrent events Open
Summary Recurrent event time data arise in many studies, including in biomedicine, public health, marketing and social media analysis. High-dimensional recurrent event data involving many event types and observations have become prevalent …
Weighted single-step genomic best linear unbiased predictor enhances the genomic prediction accuracy for milk citrate predicted by milk mid-infrared spectra of Holstein cows in early lactation Open
Previous studies have shown that milk citrate predicted by milk mid-infrared (MIR) spectra is strongly affected by a few genomic regions. This study aimed to explore the effect of weighted single-step GBLUP on the accuracy of genomic predi…
309 Synergistic optimization: Utilizing genomic insights to enhance strategies for joint selective (deep) phenotyping and recursive creation of genomic reference populations - Sponsored by EAAP Open
Synergistic optimization is a process combining different elements achieving better results than would be possible by optimizing each element individually. Our objective will be to design systems where genotyping and phenotyping complement…
Prediction of body condition score throughout lactation by random regression test‐day models Open
Regular monitoring of body condition score (BCS) changes during lactation is a crucial management tool in dairy cattle; however, the current BCS measurements are often discontinuous and unevenly spaced in time. The aim of this study was to…
Exploring a Bayesian sparse factor model-based strategy for the genetic analysis of thousands of mid-infrared spectra traits for animal breeding Open
With the rapid development of animal phenomics and deep phenotyping, we can obtain thousands of traditional (but also molecular) phenotypes per individual. However, there is still a lack of exploration regarding how to handle this huge amo…
Molecular Regulation of Porcine Skeletal Muscle Development: Insights from Research on CDC23 Expression and Function Open
Cell division cycle 23 (CDC23) is a component of the tetratricopeptide repeat (TPR) subunit in the anaphase-promoting complex or cyclosome (APC/C) complex, which participates in the regulation of mitosis in eukaryotes. However, the regulat…
Single-step genome-wide association analyses for milk urea concentration in Walloon Holstein cows Open
The aims of this study were to conduct a single-step genome-wide association to identify genomic regions associated with milk urea (MU) and to estimate genetic correlations between MU and milk yield (MY), milk composition (calcium content …
Genetic analysis of milk citrate predicted by milk mid-infrared spectra of Holstein cows in early lactation Open
Milk citrate is regarded as an early biomarker of negative energy balance in dairy cows during early lactation and serves as a suitable candidate phenotype for genomic selection due to its wide availability across a large number of cows th…
Prediction of key milk biomarkers in dairy cows through milk mid-infrared spectra and international collaborations Open
At the individual cow level, suboptimum fertility, mastitis, negative energy balance, and ketosis are major issues in dairy farming. These problems are widespread on dairy farms and have an important economic impact. The objectives of this…
Validating genomic prediction for nitrogen efficiency index and its composition traits of Holstein cows in early lactation Open
Nitrogen (N) use efficiency (NUE) is an economically important trait for dairy cows. Recently, we proposed a new N efficiency index (NEI), that simultaneously considers both NUE and N pollution. This study aimed to validate the genomic pre…
Single-step genome-wide association analyses for selected infrared-predicted cheese-making traits in Walloon Holstein cows Open
This study aimed to perform genome-wide association study to identify genomic regions associated with milk production and cheese-making properties (CMP) in Walloon Holstein cows. The studied traits were milk yield, fat percentage, protein …
Single-step genome-wide association for selected milk fatty acids in Dual-Purpose Belgian Blue cows Open
The aim of this study was to estimate genetic parameters and identify genomic regions associated with selected individual and groups of milk fatty acids (FA) predicted by milk mid-infrared spectrometry in Dual-Purpose Belgian Blue cows. Th…
Genome-wide association study and functional annotation analyses for nitrogen efficiency index and its composition traits in dairy cattle Open
The aims of this study were (1) to identify genomic regions associated with a N efficiency index (NEI) and its composition traits and (2) to analyze the functional annotation of identified genomic regions. The NEI included N intake (NINT1)…
A novel method revealing animal evolutionary relationships based on milk Mid-infrared Open
Mid-infrared spectra (MIRS) can effectively reflect the chemical bonds in milk, which has been widely used in dairy herd improvement. However, the relationship between MIRS and animal evolution remains largely unclear. This study firstly f…
View article: Identification of miR-192 target genes in porcine endometrial epithelial cells based on miRNA pull-down
Identification of miR-192 target genes in porcine endometrial epithelial cells based on miRNA pull-down Open
MicroRNAs (miRNAs)—a class of small endogenous non-coding RNAs—are widely involved in post-transcriptional gene regulation of numerous physiological processes. High-throughput sequencing revealed that the miR-192 expression level appeared …
Defining a nitrogen efficiency index in Holstein cows and assessing its potential effect on the breeding program of bulls Open
The purposes of this study were (1) to explore the relationship between 3 milk mid-infrared predicted features including nitrogen intake (NINT), milk true protein N (MTPN), and milk urea-N yield (MUNY); (2) to integrate these 3 features in…
Genetic analysis of milk urea concentration and its genetic relationship with selected traits of interest in dairy cows Open
The aim of this study was to estimate genetic parameters of milk urea concentration (MU) and its genetic correlations with milk production traits, longevity, and functional traits in the first 3 parities in dairy cows. The edited data set …
Genetic parameters for milk urea concentration in Dual-Purpose Belgian Blue cattle Open
Milk urea (MU) is a common tool used for evaluation of diet composition and feeding disorders and is related as well to reproductive performances, longevity, health and product quality (e.g. cheese making ability). In addition, the apparen…
Estimation of genetic parameters for predicted nitrogen use efficiency and losses in early lactation of Holstein cows Open
The objective of this study was to estimate genetic parameters of predicted N use efficiency (PNUE) and N losses (PNL) as proxies of N use and loss for Holstein cows. Furthermore, we have assessed approximate genetic correlations between P…
Molecular phylogenetics and evolutionary history of the endemic land snail genus <i>Everettia</i> in northern Borneo Open
Borneo has gone through dramatic changes in geology and topography from the early Eocene until the early Pliocene and experienced climatic cycling during the Pleistocene. However, how these changes have shaped the present-day patterns of h…