Yanshuang Wu
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View article: Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader
Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader Open
The process of induced pluripotent stem cells (iPSCs) reprogramming involves several crucial events, including the mesenchymal-epithelial transition (MET), activation of pluripotent genes, metabolic reprogramming, and epigenetic rewiring. …
View article: Striated preferentially expressed gene deficiency leads to mitochondrial dysfunction in developing cardiomyocytes
Striated preferentially expressed gene deficiency leads to mitochondrial dysfunction in developing cardiomyocytes Open
View article: Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate liver steatosis by promoting fatty acid oxidation and reducing fatty acid synthesis
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate liver steatosis by promoting fatty acid oxidation and reducing fatty acid synthesis Open
NAFLD includes many conditions, from simple steatosis to non-alcoholic steatohepatitis, which can lead to fibrosis, cirrhosis, and even hepatocellular carcinoma. So far, there is no approved drug for treating liver steatosis of NAFLD. Thus…
View article: Application of FBG Sensor to Safety Monitoring of Mine Shaft Lining Structure
Application of FBG Sensor to Safety Monitoring of Mine Shaft Lining Structure Open
The use of fiber Bragg grating (FBG) sensors is proposed to solve the technical problem of poor sensor stability in the long-term safety monitoring of shaft lining structures. The auxiliary shaft of the Zhuxianzhuang coal mine was consider…
View article: Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro
Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro Open
The study of human brain physiology, including cellular interactions in normal and disease conditions, has been a challenge due to its complexity and unavailability. Induced pluripotent stem cell (iPSC) study is indispensable in the study …
View article: Additional file 1 of Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro
Additional file 1 of Brain organoid: a 3D technology for investigating cellular composition and interactions in human neurological development and disease models in vitro Open
Additional file 1.
View article: Tumorigenic and Immunogenic Properties of Induced Pluripotent Stem Cells: a Promising Cancer Vaccine
Tumorigenic and Immunogenic Properties of Induced Pluripotent Stem Cells: a Promising Cancer Vaccine Open
View article: Comprehensive analysis of the SLC16A gene family in pancreatic cancer via integrated bioinformatics
Comprehensive analysis of the SLC16A gene family in pancreatic cancer via integrated bioinformatics Open
SLC16A family members play crucial roles in tumorigenesis and tumor progression. However, the exact role of distinct members in the SLC16A family in human pancreatic cancer remains unclear. Integrated bioinformatics analysis for the identi…
View article: Embryonic germ cell extracts erase imprinted genes and improve the efficiency of induced pluripotent stem cells
Embryonic germ cell extracts erase imprinted genes and improve the efficiency of induced pluripotent stem cells Open
View article: Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCs
Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCs Open
Background rDNA, the genes encoding ribosomal RNA (rRNA), is highly demanded for ribosome production and protein synthesis in growing cells such as pluripotent stem cells. rDNA transcription activity varies between cell types, metabolism c…
View article: Embryos aggregation improves development and imprinting gene expression in mouse parthenogenesis
Embryos aggregation improves development and imprinting gene expression in mouse parthenogenesis Open
Mouse parthenogenetic embryonic stem cells (Pg ESC s) could be applied to study imprinting genes and are used in cell therapy. Our previous study found that stem cells established by aggregation of two parthenogenetic embryos at 8‐cell sta…
View article: Additional file 2: Figure S1. of Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCs
Additional file 2: Figure S1. of Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCs Open
Showing MEF and S-MEF cell cycle distribution analysis. (DOCX 152Â kb)
View article: Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells
Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells Open
Exendin-4 remarkably facilitated Neurod1 and Glut2 gene transcription, and was able to induce differentiation of embryonic stem cells into endocrine and insulin-producing cells.
View article: Induction of autophagy improves embryo viability in cloned mouse embryos
Induction of autophagy improves embryo viability in cloned mouse embryos Open
View article: Study on the Fermentation Conditions of the Microbial Oils
Study on the Fermentation Conditions of the Microbial Oils Open
T-5 strains of Mortierella were screened from soil sample, which had a high lipid contents.Through the orthogonal experiment, the optimization conditions of lipid were that temperature was 28°C, pH was 6.0, glucose concentration was 100g/L…