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View article: Preoperative coronal imbalance in degenerative scoliosis: a study on coronal and sagittal spinal-pelvic parameters——a retrospective study
Preoperative coronal imbalance in degenerative scoliosis: a study on coronal and sagittal spinal-pelvic parameters——a retrospective study Open
View article: Interaction between the brain and multiple organ systems in schizophrenia
Interaction between the brain and multiple organ systems in schizophrenia Open
Schizophrenia is characterized by psychotic symptoms, negative symptoms, and cognitive deficits, profoundly affecting individuals and their families. The etiology is multifactorial, involving genetic, endocrine, and immunological risk fact…
View article: Altered Cerebro-Cerebellar Functional Connectivity Associated With Working Memory Decline After Sleep Deprivation
Altered Cerebro-Cerebellar Functional Connectivity Associated With Working Memory Decline After Sleep Deprivation Open
Background: It has been demonstrated that the cerebellum plays a critical role not only in motor function but also in cognitive function. Numerous studies have revealed that acute sleep deprivation (SD) alters the functional connectivity (…
View article: Altered Structure-Function Coupling Associated with Attention Decline in Shift Work Disorder
Altered Structure-Function Coupling Associated with Attention Decline in Shift Work Disorder Open
Our findings unravel that the decreased SC-FC coupling in the anterior cingulate gyrus may contribute to the impaired altering network function in SWD, which can further understand the neural mechanisms of impaired attention in SWD and inf…
View article: Altered Self‐Referential‐Related Brain Regions in Depersonalization‐Derealization Disorder
Altered Self‐Referential‐Related Brain Regions in Depersonalization‐Derealization Disorder Open
Objective We aimed to explore the alteration in topology and network properties in self‐referential‐related brain regions of individuals with depersonalization–derealization disorders (DPD), using evidence from resting‐state functional mag…
View article: Dysfunctional large-scale brain networks in drug-naïve depersonalization-derealization disorder patients
Dysfunctional large-scale brain networks in drug-naïve depersonalization-derealization disorder patients Open
Overall, disrupted FC of large-scale brain networks may contribute to understanding neurobiological underpinnings in DPRD. Our findings may provide potential targets for therapeutic interventions.
View article: Altered Functional Connectivity of the Thalamus Subregions Associated with Impaired Attention After Sleep Deprivation
Altered Functional Connectivity of the Thalamus Subregions Associated with Impaired Attention After Sleep Deprivation Open
Our findings reveal that the disrupted FC between thalamus subregions and cortical regions may contribute to impaired attention after SD.
View article: Altered Cerebro-Cerebellar Functional Connectivity Associated with Working Memory Decline after Sleep Deprivation
Altered Cerebro-Cerebellar Functional Connectivity Associated with Working Memory Decline after Sleep Deprivation Open
It has been demonstrated that the cerebellum plays a critical role not only in motor function but also in cognitive function. Numerous studies have revealed altered functional connectivity (FC) in cerebral cortex underlying working memory …
View article: Altered functional connectivity of thalamus subregions after sleep deprivation associated with impaired attention
Altered functional connectivity of thalamus subregions after sleep deprivation associated with impaired attention Open
Attentional function is significantly damaged by acute sleep deprivation (SD), which manifests with thalamic dysfunction and the abnormal functional connectivity (FC) of extensive brain networks. However, the FC between the thalamus subreg…
View article: Altered Functional Connectivity of Large-Scale Brain Networks in Psychogenic Erectile Dysfunction Associated with Cognitive Impairments
Altered Functional Connectivity of Large-Scale Brain Networks in Psychogenic Erectile Dysfunction Associated with Cognitive Impairments Open
Taken together, our findings revealed the relationship between cognitive impairments and altered FC between large-scale brain networks in pED patients, providing the new evidence about the neural mechanisms of cognitive dysfunction in pED …
View article: Effect of Shi-Zhen-An-Shen herbal formula granule in the treatment of young people at ultra-high risk for psychosis: a pilot study
Effect of Shi-Zhen-An-Shen herbal formula granule in the treatment of young people at ultra-high risk for psychosis: a pilot study Open
Introduction To date, there is no conclusive evidence for early interventions on ultra-high risk (UHR) for psychosis. The Chinese herbal medicine is confirmed to be beneficial in improving psychiatric symptoms and cognitive impairments for…
View article: Therapy of replenishing and regulating for manic episode in bipolar disorder: study protocol for a prospective, double-blind, randomized controlled trial.
Therapy of replenishing and regulating for manic episode in bipolar disorder: study protocol for a prospective, double-blind, randomized controlled trial. Open
Bipolar disorder (BD) is a chronic and recurrent disorder characterized by biphasic mood episodes of mania or hypomania and depression. It affects more than 1% of the global population and is a leading cause of disability in young people. …
View article: Altered functional connectivity of large-scale brain networks in psychogenic erectile dysfunction associated with cognitive impairments
Altered functional connectivity of large-scale brain networks in psychogenic erectile dysfunction associated with cognitive impairments Open
Several studies have demonstrated that psychogenic erectile dysfunction (pED) patients potentially suffer from cognitive dysfunction. Despite that previous neuroimaging studies have reported abnormal functional connections of brain areas a…
View article: Disrupted white matter network connectivity associated with cognitive declines in psychogenic erectile dysfunction
Disrupted white matter network connectivity associated with cognitive declines in psychogenic erectile dysfunction Open
Increasing neuroimaging studies have demonstrated abnormalities of cerebral structural changes in psychogenic erectile dysfunction (pED). Despite the abnormal brain changes involving cognitive processing in pED, pED patients suffer from co…
View article: Altered functional connectivity of cerebellar networks in first-episode schizophrenia
Altered functional connectivity of cerebellar networks in first-episode schizophrenia Open
Introduction Abnormalities of the cerebellum have been displayed to be a manifestation of schizophrenia (SCH) which is a detrimental psychiatric disorder. It has been recognized that the cerebellum contributes to motor function, sensorimot…
View article: Protective Effects of Shi-Zhen-An-Shen Decoction on the Cognitive Impairment in MK801-Induced Schizophrenia Model
Protective Effects of Shi-Zhen-An-Shen Decoction on the Cognitive Impairment in MK801-Induced Schizophrenia Model Open
Background: Cognitive dysfunction is a core feature of schizophrenia that strongly correlates to the patients’ difficulties in independent living and occupational functioning. Synaptic dysfunction may result in cognitive and behavioral cha…
View article: Potential Targets for Noninvasive Brain Stimulation on Depersonalization-Derealization Disorder
Potential Targets for Noninvasive Brain Stimulation on Depersonalization-Derealization Disorder Open
Introduction: Non-invasive brain stimulation seems to be beneficial for DPD patients. However, the sites used in previous studies were empirical. Exploring new stimulation locations via functional magnetic resonance imaging may improve the…
View article: The altered intrinsic functional connectivity after acupuncture at shenmen (HT7) in acute sleep deprivation
The altered intrinsic functional connectivity after acupuncture at shenmen (HT7) in acute sleep deprivation Open
Introduction Accumulating evidence has shown that acupuncture could significantly improve the sleep quality and cognitive function of individuals suffering from insufficient sleep. Numerous animal studies have confirmed the effects and mec…
View article: Altered Functional Connectivity and Topological Organization of Brain Networks Correlate to Cognitive Impairments After Sleep Deprivation
Altered Functional Connectivity and Topological Organization of Brain Networks Correlate to Cognitive Impairments After Sleep Deprivation Open
The study was registered at the Chinese Clinical Trial Registry, registration ID: ChiCTR2000039858, China.
View article: Attention Performance Correlated With White Matter Structural Brain Networks in Shift Work Disorder
Attention Performance Correlated With White Matter Structural Brain Networks in Shift Work Disorder Open
Neuroimaging studies have revealed that shift work disorder (SWD) affected the functional connectivity in specific brain regions and networks. However, topological disruptions in the structural connectivity of the white matter (WM) network…
View article: Ameliorative Effects of Shi-Zhen-An-Shen Decoction on the Cognitive Impairment of MK801-Induced Rats: A Potential Therapeutic Approach for Schizophrenia
Ameliorative Effects of Shi-Zhen-An-Shen Decoction on the Cognitive Impairment of MK801-Induced Rats: A Potential Therapeutic Approach for Schizophrenia Open
View article: Potential Locations for Non-Invasive Brain Stimulation in Treating Schizophrenia: A Resting-State Functional Connectivity Analysis
Potential Locations for Non-Invasive Brain Stimulation in Treating Schizophrenia: A Resting-State Functional Connectivity Analysis Open
Introduction: Non-invasive brain stimulation (NIBS) techniques have been widely used for the purpose of improving clinical symptoms of schizophrenia. However, the ambiguous stimulation targets may limit the efficacy of NIBS for schizophren…
View article: INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial
INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial Open
View article: Paliperidone Compared with Haloperidol on the Theory of Mind Tasks in Schizophrenia: A Pilot Trial
Paliperidone Compared with Haloperidol on the Theory of Mind Tasks in Schizophrenia: A Pilot Trial Open
chictr.org.cn_identifier ChiCTR-IPR-15007635.
View article: Disrupted Resting-State Functional Connectivity between the Dorsal Attention, Default Mode, and Frontoparietal Networks in Nonorganic Gastrointestinal Disorder Patients with Spleen Deficiency Syndrome
Disrupted Resting-State Functional Connectivity between the Dorsal Attention, Default Mode, and Frontoparietal Networks in Nonorganic Gastrointestinal Disorder Patients with Spleen Deficiency Syndrome Open
Introduction. Spleen deficiency syndrome (SDS), a common clinical syndrome of traditional Chinese medicine, is manifested with digestive symptoms and cognitive impairments. However, the cognitive neural mechanism in brain networks of SDS s…
View article: Shi-Zhen-An-Shen Decoction, a Herbal Medicine That Reverses Cuprizone-Induced Demyelination and Behavioral Deficits in Mice Independent of the Neuregulin-1 Pathway
Shi-Zhen-An-Shen Decoction, a Herbal Medicine That Reverses Cuprizone-Induced Demyelination and Behavioral Deficits in Mice Independent of the Neuregulin-1 Pathway Open
Shi-Zhen-An-Shen decoction (SZASD), a Chinese herbal medicine that is a liquor extracted from plants by boiling, has been reported to be effective in treating schizophrenia. However, the mechanism is unclear. Abnormal demyelination has bee…
View article: The fMRI study for acupuncture on shift work sleep disorder
The fMRI study for acupuncture on shift work sleep disorder Open
Introduction: Nearly 20% of night shift nurses will cause shift work disorder (SWD) due to the disruption of sleep-wake cycle, which not only affects the daily work efficiency, but also brings a huge burden on physical and mental health. A…
View article: Efficacy and safety of Jie-du-qing-nao granules for first-episode schizophrenics: study protocol for a randomized controlled trial
Efficacy and safety of Jie-du-qing-nao granules for first-episode schizophrenics: study protocol for a randomized controlled trial Open
BackgroundAt present, the focus and difficulty of schizophrenia (SCZ) treatment is to improve cognitive function and negative symptoms. Jie-du-qing-nao granules(JQG) , a traditional Chinese medicine(TCM) prescription , has a good clinical …
View article: Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis
Acupuncture Modulates Disrupted Whole-Brain Network after Ischemic Stroke: Evidence Based on Graph Theory Analysis Open
Background . Stroke can lead to disruption of the whole-brain network in patients. Acupuncture can modulate the functional network on a large-scale level in healthy individuals. However, whether and how acupuncture can make a potential imp…
View article: Assessing Cognitive Abilities of Patients With Shift Work Disorder: Insights From RBANS and Granger Causality Connections Among Resting-State Networks
Assessing Cognitive Abilities of Patients With Shift Work Disorder: Insights From RBANS and Granger Causality Connections Among Resting-State Networks Open
This study indicates that SWD impairs cognitive performance, and the specific intrinsic brain granger causality connectivity among resting-state networks in SWD patients is affected after long-term shift works.