Yao Hao Teo
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View article: Clinical Characteristics and Outcomes of a Cohort of Multiethnic Asian Patients with Cardiac Myxoma
Clinical Characteristics and Outcomes of a Cohort of Multiethnic Asian Patients with Cardiac Myxoma Open
View article: Inpatient‐Onset Versus Outpatient‐Onset ST‐Segment–Elevation Myocardial Infarction in Patients With Percutaneous Coronary Intervention: A National Registry Study
Inpatient‐Onset Versus Outpatient‐Onset ST‐Segment–Elevation Myocardial Infarction in Patients With Percutaneous Coronary Intervention: A National Registry Study Open
Background Compared with patients who develop ST‐segment–elevation myocardial infarction (STEMI) outside the hospital and present at the emergency department (outpatient‐onset), patients with inpatient‐onset STEMI may paradoxically experie…
View article: The Impact of Sarcopenic Obesity on Frailty, Cognition, and Function in Community-Dwelling Older Adults
The Impact of Sarcopenic Obesity on Frailty, Cognition, and Function in Community-Dwelling Older Adults Open
SO is associated with greater risks of frailty, cognitive impairment, functional decline, and mobility limitations than sarcopenia or obesity alone.
View article: Cerebral Small‐Vessel Disease Markers on Magnetic Resonance Imaging as Predictors of Recurrent Vascular Events and Death in Ischemic Stroke: A Systematic Review and Meta‐Analysis
Cerebral Small‐Vessel Disease Markers on Magnetic Resonance Imaging as Predictors of Recurrent Vascular Events and Death in Ischemic Stroke: A Systematic Review and Meta‐Analysis Open
Background Cerebral small‐vessel disease encompasses a spectrum of magnetic resonance imaging features reflecting microvascular pathology in ischemic stroke. Among these, white matter hyperintensities (WMHs) and cerebral microbleeds (CMBs)…
View article: Response to Comment on Wong et al. Efficacy of GLP-1 Receptor Agonists on Weight Loss, BMI, and Waist Circumference for Patients With Obesity or Overweight: A Systematic Review, Meta-analysis, and Meta-regression of 47 Randomized Controlled Trials. Diabetes Care 2025;48:292–300
Response to Comment on Wong et al. Efficacy of GLP-1 Receptor Agonists on Weight Loss, BMI, and Waist Circumference for Patients With Obesity or Overweight: A Systematic Review, Meta-analysis, and Meta-regression of 47 Randomized Controlled Trials. Diabetes Care 2025;48:292–300 Open
View article: Stroke Risk in Head and Neck Cancer: A Meta‐analysis of Reconstructed Individual Patient Survival Data
Stroke Risk in Head and Neck Cancer: A Meta‐analysis of Reconstructed Individual Patient Survival Data Open
Objective Although previous studies suggest an increased stroke risk in head and neck cancer (HNC) survivors, the risk with various treatment modalities, including radiotherapy, is less certain. This study investigates stroke incidence and…
View article: Return to Work After Ischemic Stroke in Young Adults: A Multicenter Cohort Study, Systematic Review, and Meta‐Analysis
Return to Work After Ischemic Stroke in Young Adults: A Multicenter Cohort Study, Systematic Review, and Meta‐Analysis Open
Background Ischemic stroke incidence in young adults is increasing globally, with return to work (RTW) a key rehabilitation goal. We aimed to assess the overall proportions of and factors associated with RTW following young adult ischemic …
View article: Efficacy of GLP-1 receptor agonists on weight loss, body mass index and waist circumference for obese or overweight patients: A systematic review, meta-analysis and meta-regression of 47 randomized-controlled trials
Efficacy of GLP-1 receptor agonists on weight loss, body mass index and waist circumference for obese or overweight patients: A systematic review, meta-analysis and meta-regression of 47 randomized-controlled trials Open
BackgroundGlucagon-like peptide-1 receptor agonists (GLP-1RAs) have advanced rapidly in recent years.PurposeAn updated synthesis on effects of GLP-1RAs on weight, BMI and waist circumference incorporating newer RCTs, particularly in overwe…
View article: Efficacy of GLP-1 receptor agonists on weight loss, body mass index and waist circumference for obese or overweight patients: A systematic review, meta-analysis and meta-regression of 47 randomized-controlled trials
Efficacy of GLP-1 receptor agonists on weight loss, body mass index and waist circumference for obese or overweight patients: A systematic review, meta-analysis and meta-regression of 47 randomized-controlled trials Open
BackgroundGlucagon-like peptide-1 receptor agonists (GLP-1RAs) have advanced rapidly in recent years.PurposeAn updated synthesis on effects of GLP-1RAs on weight, BMI and waist circumference incorporating newer RCTs, particularly in overwe…
View article: Deep-learning-derived neuroimaging biomarkers of sarcopenia as predictors of outcome in endovascular thrombectomy in large vessel occlusion acute ischemic stroke
Deep-learning-derived neuroimaging biomarkers of sarcopenia as predictors of outcome in endovascular thrombectomy in large vessel occlusion acute ischemic stroke Open
Introduction Sarcopenia is an emerging marker of biological health and is associated with poor outcomes in many disease states. In this study, we aimed to evaluate the utility of muscle biomarkers in predicting clinical outcomes for patien…
View article: Sleep Apnea and Cardiovascular Outcomes in Patients Undergoing Coronary Artery Bypass Grafting
Sleep Apnea and Cardiovascular Outcomes in Patients Undergoing Coronary Artery Bypass Grafting Open
View article: Accuracy of machine learning in predicting outcomes post-percutaneous coronary intervention: a systematic review
Accuracy of machine learning in predicting outcomes post-percutaneous coronary intervention: a systematic review Open
BACKGROUND: Recent studies have shown potential in introducing machine learning (ML) algorithms to predict outcomes post-percutaneous coronary intervention (PCI). AIMS: We aimed to critically appraise current ML models’ effectiveness as cl…
View article: Assessment of Left Atrial Fibrosis by Cardiac Magnetic Resonance Imaging in Ischemic Stroke Patients Without Atrial Fibrillation: A Systematic Review and Meta‐Analysis
Assessment of Left Atrial Fibrosis by Cardiac Magnetic Resonance Imaging in Ischemic Stroke Patients Without Atrial Fibrillation: A Systematic Review and Meta‐Analysis Open
Background Left atrial (LA) fibrosis is a marker of atrial cardiomyopathy and has been reported to be associated with both atrial fibrillation and ischemic stroke. Elucidating this relationship is clinically important as LA fibrosis could …
View article: Impact of Youth Health Ambassador Programme on health awareness in youths in Singapore
Impact of Youth Health Ambassador Programme on health awareness in youths in Singapore Open
BACKGROUND: The Youth Health Ambassador Programme (YHAP) is a health educational program aimed at empowering youths to become health ambassadors in the community through raising their health awareness and training them in primary health pr…
View article: Contemporary Incidence of Cognitive Impairment or Dementia in Patients Undergoing Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis
Contemporary Incidence of Cognitive Impairment or Dementia in Patients Undergoing Coronary Artery Bypass Grafting: A Systematic Review and Meta-Analysis Open
Introduction: Despite the high prevalence of cognitive impairment or dementia post-coronary artery bypass grafting (CABG), the incidence of cognitive impairment or dementia post-CABG in contemporary practice is currently uncl…
View article: Machine Learning Modeling to Predict Atrial Fibrillation Detection in Embolic Stroke of Undetermined Source Patients
Machine Learning Modeling to Predict Atrial Fibrillation Detection in Embolic Stroke of Undetermined Source Patients Open
Background: In patients with embolic stroke of undetermined source (ESUS), occult atrial fibrillation (AF) has been implicated as a key source of cardioembolism. However, only a minority acquire implantable cardiac loop recorders (ILRs) to…
View article: Migraine and atrial fibrillation: a systematic review and meta-analysis
Migraine and atrial fibrillation: a systematic review and meta-analysis Open
Background: Patients with migraines, particularly those with auras, may present with stroke. Atrial fibrillation is a known risk factor for stroke. With common pathophysiological factors between migraines and atrial fibrillation, we aimed …
View article: Evaluating time in therapeutic range in post-acute myocardial infarction patients with left ventricular thrombus treated with vitamin K antagonist
Evaluating time in therapeutic range in post-acute myocardial infarction patients with left ventricular thrombus treated with vitamin K antagonist Open
Background The standard of care for the treatment of post-acute myocardial infarction (AMI) patients with left ventricular (LV) thrombus is oral anticoagulation with vitamin K antagonist (VKA). Due to the narrow therapeutic range of VKA, p…
View article: Meta-analysis of cardiac imaging modalities for the diagnosis of left ventricular thrombus following acute myocardial infarction
Meta-analysis of cardiac imaging modalities for the diagnosis of left ventricular thrombus following acute myocardial infarction Open
Background The formation of left ventricular thrombus (LVT) in post-acute myocardial infarction (AMI) patient carries significant risk of systemic embolism. Hence, there is a need to adopt strategies aimed at accurate and early diagnosis o…
View article: Clinical characteristics and outcomes of left ventricular thrombus patients with mildly reduced and preserved left ventricular ejection fraction
Clinical characteristics and outcomes of left ventricular thrombus patients with mildly reduced and preserved left ventricular ejection fraction Open
Background Abnormal left ventricular ejection fraction (LVEF) is associated with the development of left ventricular thrombus (LVT) following acute myocardial infarction and also in non-ischaemic cardiomyopathies. LVT formation in normal L…
View article: Differences in clinical characteristics and outcomes between patients with left ventricular thrombus following non-anterior and anterior ST-elevation myocardial infarction
Differences in clinical characteristics and outcomes between patients with left ventricular thrombus following non-anterior and anterior ST-elevation myocardial infarction Open
Background Left ventricular thrombus (LVT) is a serious complication following ST-elevation myocardial infarction (STEMI), and occurs more frequently in anterior compared to non-anterior myocardial infarction (MI).1 There is limited data o…
View article: Care transition processes in the Singapore healthcare system: process mapping and perspectives of private primary care practitioners
Care transition processes in the Singapore healthcare system: process mapping and perspectives of private primary care practitioners Open
INTRODUCTION The Singapore Ministry of Health (MOH) utilises 'Beyond hospital to community' as a policy strategy, shifting the focus of care from secondary and tertiary healthcare institutions to primary care and the intermediate and long-…
View article: Obstructive sleep apnea and temporal changes in cardiac repolarization in patients undergoing coronary artery bypass grafting
Obstructive sleep apnea and temporal changes in cardiac repolarization in patients undergoing coronary artery bypass grafting Open
Teo YH, Yong CL, Ou YH, et al. Obstructive sleep apnea and temporal changes in cardiac repolarization in patients undergoing coronary artery bypass grafting. J Clin Sleep Med. 2024;20(1):49-55.
View article: Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review
Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review Open
Cognitive impairment (CI) shares common cardiovascular risk factors with acute myocardial infarction (AMI), and is increasingly prevalent in our ageing population. Whilst AMI is associated with increased rates of CI, CI remains underreport…
View article: Thrombectomy for distal medium vessel occlusion stroke: Combined vs. single-device techniques - A systematic review and meta-analysis
Thrombectomy for distal medium vessel occlusion stroke: Combined vs. single-device techniques - A systematic review and meta-analysis Open
Background The optimal mechanical thrombectomy technique for acute ischaemic stroke (AIS) caused by distal, medium vessel occlusion (DMVO) is uncertain. We performed a systematic review and meta-analysis evaluating the efficacy and safety …
View article: Association of Shunt Size and Long-Term Clinical Outcomes in Patients with Cryptogenic Ischemic Stroke and Patent Foramen Ovale on Medical Management
Association of Shunt Size and Long-Term Clinical Outcomes in Patients with Cryptogenic Ischemic Stroke and Patent Foramen Ovale on Medical Management Open
Introduction: Patent foramen ovale (PFO) is a potential source of cardiac embolism in cryptogenic ischemic stroke, but it may also be incidental. Right-to-left shunt (RLS) size may predict PFO-related stroke, but results have been controve…
View article: Real-world comparison of intracoronary imaging and fractional flow reserve measurements on outcomes of semi-urgent and elective percutaneous coronary intervention in a multi-ethnic asian population
Real-world comparison of intracoronary imaging and fractional flow reserve measurements on outcomes of semi-urgent and elective percutaneous coronary intervention in a multi-ethnic asian population Open
Funding Acknowledgements Type of funding sources: None. Background Intracoronary imaging and fractional flow reserve measurements (FFR) are helpful in optimisation of percutaneous coronary intervention (PCI) for patients with stable corona…
View article: Natural history of functional mitral regurgitation: a systematic review and individual patient data meta-analysis
Natural history of functional mitral regurgitation: a systematic review and individual patient data meta-analysis Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Ching-Hui Sia was supported by the National University of Singapore Yong Loo Lin School of Medicine's Junior Academic Fellowship Scheme. Backg…
View article: Effects of medical therapy, transcatheter intervention, and surgery on outcomes of patients with functional mitral regurgitation: a systematic review and network meta-analysis
Effects of medical therapy, transcatheter intervention, and surgery on outcomes of patients with functional mitral regurgitation: a systematic review and network meta-analysis Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Ching-Hui Sia was supported by the National University of Singapore Yong Loo Lin School of Medicine's Junior Academic Fellowship Scheme. Backg…
View article: Distal medium vessel occlusions in acute ischaemic stroke – Stent retriever versus direct aspiration: A systematic review and meta-analysis
Distal medium vessel occlusions in acute ischaemic stroke – Stent retriever versus direct aspiration: A systematic review and meta-analysis Open
Background Acute ischaemic stroke due to distal medium vessel occlusion (AIS-DMVO) causes significant morbidity. Endovascular thrombectomy advancement has made treating AIS-DMVO with stent retrievers (SR) and aspiration catheters (AC) poss…