Ming Yao
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View article: Letermovir Prophylaxis for <scp>CMV DNAemia</scp> /Disease after <scp>HLA</scp> ‐Mismatched <scp>HSCT</scp> : A Retrospective Real‐World Analysis with Overlap Propensity Score Weighting
Letermovir Prophylaxis for <span>CMV DNAemia</span> /Disease after <span>HLA</span> ‐Mismatched <span>HSCT</span> : A Retrospective Real‐World Analysis with Overlap Propensity Score Weighting Open
Whether letermovir benefits high‐risk HLA‐mismatched allogeneic hematopoietic stem cell transplantation (allo‐HSCT), particularly with GIAC‐based conditioning, is not well studied. In this retrospective real‐world analysis, we evaluated th…
The disaster law and control measures of high-stress tunnels in fault areas: a case study Open
In recent years, the frequent occurrence of dynamic disasters in tunnels with high stress in fault areas has greatly threatened engineering safety. The typical case - a tunnel influenced by fault slip on is taken as a research object. A se…
Prognostic Impact of Lymphocyte to Monocyte Ratio in Patients with Myelodysplastic Neoplasms/Syndromes Open
Purpose Myelodysplastic syndromes/neoplasms (MDS) represent a heterogeneous group of clonal hematopoietic disorders with variable prognosis. While several risk models exist, the prognostic role of immune-related biomarkers remains unclear.…
View article: Integrated Physiological and Transcriptomic Analysis Reveals Transcription Factors Are Crucial for Melatonin‐Mediated Drought Tolerance in <i>E. ulmoides</i>
Integrated Physiological and Transcriptomic Analysis Reveals Transcription Factors Are Crucial for Melatonin‐Mediated Drought Tolerance in <i>E. ulmoides</i> Open
Eucommia ulmoides is a Chinese herbal medicine, and much attention has been paid to its tolerance mechanism under stress conditions. Among them, drought is a severe stress that affects the plant's growth and development. Here, we assessed …
View article: Real-world analysis of autologous stem cell transplantation in primary central nervous system lymphoma using Taiwan Blood and Marrow Transplantation Registry (TBMTR)
Real-world analysis of autologous stem cell transplantation in primary central nervous system lymphoma using Taiwan Blood and Marrow Transplantation Registry (TBMTR) Open
Although high-dose chemotherapy with autologous stem cell transplantation (HDC/ASCT) is an established consolidation strategy for primary central nervous system lymphoma (PCNSL), real-world data remain limited, especially in Asia. This ret…
View article: P-518 Insights from patients: the role of multicycle counseling in enhancing treatment conversion and reducing discontinuation
P-518 Insights from patients: the role of multicycle counseling in enhancing treatment conversion and reducing discontinuation Open
Study question How do patients perceive IVF counseling, and how does it impact conversion from second consultation to treatment, and likelihood of discontinuation after a failed attempt? Summary answer Being aware of psychological-support …
View article: Large-scale Local Deployment of DeepSeek-R1 in Pilot Hospitals in China: A Nationwide Cross-sectional Survey
Large-scale Local Deployment of DeepSeek-R1 in Pilot Hospitals in China: A Nationwide Cross-sectional Survey Open
Summary Background The open-source release of DeepSeek-R1, a high-performing large language model (LLM), enables local deployment in Chinese hospitals. However, empirical data on deployment scale, hospital characteristics, and functional a…
Simultaneous adsorption of organic phosphonate and orthophosphate from municipal sewage on nanoparticle Fe3O4 with molecular simulation Open
Organic and inorganic phosphonates often co-exist in municipal sewage, and it is a challenge to remove them simultaneously. Nanoparticle Fe3O4 (Fe3O4 NPs) has attracted significant attention due to its high adsorption activity, low cost, e…
View article: Perceptual-Preference-Based Touring Routes in Xishu Gardens Using Panoramic Digital-Twin Modeling
Perceptual-Preference-Based Touring Routes in Xishu Gardens Using Panoramic Digital-Twin Modeling Open
Xishu Gardens, an exemplary narrative of classical Chinese gardens, faces challenges in preserving its commemorative spatial structures while accommodating modern visitors’ needs. While trajectory analysis is critical, existing studies str…
Impacts of Average Real Variability Parameters of Blood Pressure on Recovery Following Posterior Fixation Surgery for Thoracolumbar Vertebral Fractures Open
AIM: This study aimed to investigate the influence of average real variability (ARV) parameters of blood pressure on the recovery following posterior fixation surgery for thoracolumbar vertebral fractures. METHODS: A retrospective analysis…
View article: Hospital-Based Registry Analysis of Staging Efficacy and Proposed Staging Subclassification for Stage I HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Hospital-Based Registry Analysis of Staging Efficacy and Proposed Staging Subclassification for Stage I HPV-Associated Oropharyngeal Squamous Cell Carcinoma Open
Substaging of AJCC8 stage I for HPV-associated OPSCC by cT2 and cN2b (7thedition TNM stage) provided significant hazard consistency. Adoption may improve prognostic risk stratification and inform guidance in treatment decision making. Furt…
Both consolidation and maintenance treatment improve outcomes in primary central nervous system lymphoma: real-world evidence from a tertiary medical center Open
Background: Intensive consolidation treatment following high-dose methotrexate (HDMTX)-based chemotherapy is recommended for fit patients with primary central nervous system lymphoma (PCNSL). Otherwise, HDMTX maintenance might be a useful …
View article: Nonmotor Symptom Changes and Their Association With Falls Among Parkinson's Disease Patients Undergoing Deep Brain Stimulation: A 1‐Year Cohort Study
Nonmotor Symptom Changes and Their Association With Falls Among Parkinson's Disease Patients Undergoing Deep Brain Stimulation: A 1‐Year Cohort Study Open
Objectives Fall severely affects the quality of life of Parkinson's disease (PD) patients. Subthalamic nucleus (STN) deep brain stimulation (DBS) is an effective treatment for PD motor symptoms (MS), but DBS increased the risk of falls in …
Multisensory Health and Well-Being of Chinese Classical Gardens: Insights from Humble Administrator’s Garden Open
Chinese classical gardens serve as restorative environments that epitomize the essence of Chinese aesthetics. Despite their recognized Outstanding Universal Value, research on the multisensory experiences and associated well-being benefits…
View article: Derivation of a comprehensive semi-empirical proton RBE model from published experimental cell survival data collected in the PIDE database
Derivation of a comprehensive semi-empirical proton RBE model from published experimental cell survival data collected in the PIDE database Open
We aimed to develop a comprehensive proton relative biological effectiveness (RBE) model based on accumulated cell survival data in the literature. Our approach includes four major components: (1) Eligible cell survival data with various l…
The application of the “PICO” teaching model in clinical research course for medical students Open
Objectives This study aimed to compare the effectiveness of the “PICO”, which stands for Patient, Intervention, Comparison, and Outcome, teaching model with traditional didactic teaching in clinical research education. Methods 90 eight-yea…
Targeted treatment of gastric cancer and its pathogenic mechanism Open
Gastric cancer (GC) is a malignant tumor with high morbidity and mortality in our country. The traditional treatment methods include operation, radiotherapy and chemotherapy. At present, it cannot be cured by traditional treatment. Targete…
View article: <i>SRSF2</i> Mutation Cooperates with <i>ASXL1</i> Mutation to Promote the Development of Myeloproliferative Variant of Chronic Myelomonocytic Leukemia
<i>SRSF2</i> Mutation Cooperates with <i>ASXL1</i> Mutation to Promote the Development of Myeloproliferative Variant of Chronic Myelomonocytic Leukemia Open
Introduction: Chronic myelomonocytic leukaemia (CMML) is a heterogenous haematopoietic stem cell (HSC) disorder characterized by sustained (>3 months) relative (≥10%) and absolute (≥0.5×109/L) monocytosis in peripheral blood (PB), and subc…