Yaoqiang Shi
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View article: Bacterial Extracellular Vesicles: An Emerging Concern in the Field of Environmental Contamination—Characterization, Impacts, and Response Strategies
Bacterial Extracellular Vesicles: An Emerging Concern in the Field of Environmental Contamination—Characterization, Impacts, and Response Strategies Open
Bacterial extracellular vesicles (BEVs) are nanoscale membrane-bound structures secreted by prokaryotic cells and have recently gained considerable attention in environmental pollution research. By encapsulating virulence factors and antib…
View article: Challenge of Rabies Elimination from the Scenarios In Which a Rabid Dog Bit Multiple People, Including Children, and Phylogenetic Analysis of Rabies Virus
Challenge of Rabies Elimination from the Scenarios In Which a Rabid Dog Bit Multiple People, Including Children, and Phylogenetic Analysis of Rabies Virus Open
View article: Oncolytic Virus Senecavirus A Inhibits Hepatocellular Carcinoma Proliferation and Growth by Inducing Cell Cycle Arrest and Apoptosis
Oncolytic Virus Senecavirus A Inhibits Hepatocellular Carcinoma Proliferation and Growth by Inducing Cell Cycle Arrest and Apoptosis Open
SVA inhibits the growth of HCC cells by inducing cell cycle arrest and apoptosis. It does not cause any noticeable toxicity to vital organs.
View article: Hsa_circ_0007321 regulates Zika virus replication through miR-492/NFKBID/NF-κB signaling pathway
Hsa_circ_0007321 regulates Zika virus replication through miR-492/NFKBID/NF-κB signaling pathway Open
Circular RNAs (CircRNAs) have been shown to play a critical role in regulating viral infection and replication. We performed RNA sequencing to identify differentially expressed circRNAs in A549 human lung adenocarcinoma cells with and with…
View article: The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety
The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety Open
A small percentage of couples who regularly donated blood in China tested positive for HBsAg. Although it is well known that blood donors can acquire hepatitis B virus (HBV) infection from a chronically infected sexual partner, the prevale…
View article: UMP-CMP kinase 2 Inhibits ZIKV Replication through Activation of Type I IFN Signaling Pathway
UMP-CMP kinase 2 Inhibits ZIKV Replication through Activation of Type I IFN Signaling Pathway Open
Background : Cytidine/uridine monophosphate kinase 2 (UMP-CMP kinase 2, CMPK2) has been reported as an antiviral interferon-stimulated gene (ISG). We previously observed that the expression of CMPK2 was significantly upregulated after Zika…
View article: CRISPR/Cas12a-Enhanced Loop-Mediated Isothermal Amplification for the Visual Detection of Shigella flexneri
CRISPR/Cas12a-Enhanced Loop-Mediated Isothermal Amplification for the Visual Detection of Shigella flexneri Open
Shigella flexneri is a serious threat to global public health, and a rapid detection method is urgently needed. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system is widely used in gene edit…
View article: Outer membrane protein A (OmpA) may be used as a novel target to enrich and detect Escherichia coli in milk samples
Outer membrane protein A (OmpA) may be used as a novel target to enrich and detect Escherichia coli in milk samples Open
In recent years, food safety incidents caused by Escherichia coli have occurred and have endangered human health. Due to the complex matrix of milk samples and the long pretreatment time, the existing methods cannot quickly detect E. coli …
View article: WarmStart colorimetric loop-mediated isothermal amplification for the one-tube, contamination-free and visualization detection of Shigella flexneri
WarmStart colorimetric loop-mediated isothermal amplification for the one-tube, contamination-free and visualization detection of Shigella flexneri Open
View article: Cathelicidin-DM is an Antimicrobial Peptide from <i>Duttaphrynus melanostictus</i> and Has Wound-Healing Therapeutic Potential
Cathelicidin-DM is an Antimicrobial Peptide from <i>Duttaphrynus melanostictus</i> and Has Wound-Healing Therapeutic Potential Open
Antimicrobial peptides (AMPs) are a class of templates with application potential for drug development. Amphibians are important sources of AMPs. Duttaphrynus melanostictus is the main source of traditional Chinese medicine "Chansu"…
View article: Peer Review #2 of "A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction (v0.1)"
Peer Review #2 of "A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction (v0.1)" Open
Background.Antibiotics are highly effective drugs used in the treatment of infectious diseases.Aminoglycoside antibiotics are one of the most common antibiotics in the treatment of bacterial infections.However, the development of drug resi…
View article: A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of <i>Escherichia coli</i> by a multiplex polymerase chain reaction
A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of <i>Escherichia coli</i> by a multiplex polymerase chain reaction Open
Background Antibiotics are highly effective drugs used in the treatment of infectious diseases. Aminoglycoside antibiotics are one of the most common antibiotics in the treatment of bacterial infections. However, the development of drug re…
View article: Peer Review #1 of "A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction (v0.1)"
Peer Review #1 of "A rapid and accurate method for the detection of four aminoglycoside modifying enzyme drug resistance gene in clinical strains of Escherichia coli by a multiplex polymerase chain reaction (v0.1)" Open
Background.Antibiotics are highly effective drugs used in the treatment of infectious diseases.Aminoglycoside antibiotics are one of the most common antibiotics in the treatment of bacterial infections.However, the development of drug resi…
View article: Emergence of Multidrug-Resistant Staphylococci on Hand-Touching Surfaces in a University Town in Southwestern China: A Prevalence Study of Virulence and Resistance
Emergence of Multidrug-Resistant Staphylococci on Hand-Touching Surfaces in a University Town in Southwestern China: A Prevalence Study of Virulence and Resistance Open
Background: Staphylococcus aureus and coagulase-negative staphylococci are highly antibiotic-resistant pathogens and exhibit multiple virulence factors that threaten public health. However, few reports have evaluated the resistance and vir…
View article: Visual and Rapid Detection of Klebsiella pneumoniae by Magnetic Immunocapture-Loop-Mediated Isothermal Amplification Assay
Visual and Rapid Detection of Klebsiella pneumoniae by Magnetic Immunocapture-Loop-Mediated Isothermal Amplification Assay Open
Background: Klebsiella pneumoniae is an important human pathogen that causes severe diseases including urinary tract infection, pneumonia, and bacteremia. However, a rapid and sensitive detection method remains to be developed. Objectives:…
View article: Rapid, specific, and sensitive detection of the ureR_1 gene in Klebsiella pneumoniae by loop-mediated isothermal amplification method
Rapid, specific, and sensitive detection of the ureR_1 gene in Klebsiella pneumoniae by loop-mediated isothermal amplification method Open
Klebsiella pneumoniae is one of the main pathogenic bacteria that causes nosocomial infections, such as pneumonia, urinary tract infection, and sepsis. Therefore, the rapid and accurate detection of K. pneumoniae is important for the timel…
View article: Establishment of loop‑mediated isothermal amplification for rapid detection of Pseudomonas aeruginosa
Establishment of loop‑mediated isothermal amplification for rapid detection of Pseudomonas aeruginosa Open
Pseudomonas aeruginosa is one of the three most pathogenic bacteria that frequently cause life-threatening opportunistic human infections, pneumonia, and lower respiratory tract infections in immunocompromised hosts, particularly in…