Yasemin Hasimoglu
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View article: Association of plasma neurofilament light chain with microstructural white matter changes in Down syndrome
Association of plasma neurofilament light chain with microstructural white matter changes in Down syndrome Open
INTRODUCTION Both micro‐ and macrostructural white matter (WM) abnormalities, particularly those related to axonal degeneration, are associated with cognitive decline in adults with Down syndrome (DS) prior to a diagnosis of Alzheimer dise…
View article: Alterations in white matter integrity in cognitively stable Down syndrome correlate with plasma neurofilament light chain: Evidence of early myelin breakdown
Alterations in white matter integrity in cognitively stable Down syndrome correlate with plasma neurofilament light chain: Evidence of early myelin breakdown Open
Background Alterations in white matter (WM) integrity occur in adults with DS during the early stage of dementia. These changes may be documented by diffusion tensor imaging wherein increases in radial diffusivity (RD), a marker of dysmyel…
View article: Does Serum Urate Change as Parkinson’s Disease Progresses?
Does Serum Urate Change as Parkinson’s Disease Progresses? Open
Higher serum urate concentration is associated with decreased risk of Parkinson’s disease (PD) as well as slower disease progression, but its relationship with severity of PD remains unclear. This study investigated whether changes in seru…