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View article: Prediction of Prostate Cancer From Routine Laboratory Markers With Automated Machine Learning
Prediction of Prostate Cancer From Routine Laboratory Markers With Automated Machine Learning Open
Background In this study, we attempted to select the optimum cases for a prostate biopsy based on routine laboratory test results in addition to prostate‐specific antigen (PSA) blood test using H2O automated machine learning (AutoML) softw…
View article: Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems
Differences in second trimester risk estimates for trisomy 21 between Maglumi X3/Preaccu and Immulite/Prisca systems Open
Objectives Maternal serum alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG) or free β-HCG, and unconjugated estriol (uE3) concentrations are used to screen trisomy 21 in the second trimester. The performance of different analytic…
View article: Association between serum NUCB2/nesfatin‑1 levels and erectile dysfunction
Association between serum NUCB2/nesfatin‑1 levels and erectile dysfunction Open
Erectile dysfunction (ED) is one of the most common complaints in the male sexual health field, with a multifactorial etiology yet to be fully elucidated. Nucleobindin 2 (NUCB2)/nesfatin-1, known for its regulatory role in food intake, can…
View article: The relationship of serotonin level with syndrome X and coronary artery disease
The relationship of serotonin level with syndrome X and coronary artery disease Open
Aims: Platelets secrete serotonin (5-hydroxytryptamine) which has several effects on the vascular wall and promotes thrombogenesis, mitogenesis, and proliferation of smooth muscle cells. We thought serotonin which relation with coronary ar…
View article: The Relation between Plasma Nesfatin-1 Levels and Aggressive Behavior in Pit Bull Dogs
The Relation between Plasma Nesfatin-1 Levels and Aggressive Behavior in Pit Bull Dogs Open
Aggression is a prevalent and concerning behavioral issue in dogs. Pit Bull dogs, known for their high levels of aggression, are recognized as a focus of concern in society. In our study, we aimed to investigate the behavioral characterist…
View article: Vitamin D in Patients with Cardiac Syndrome X and its Relationship with Inflamatuar and Oxidative Stress Markers: A Case Control Study
Vitamin D in Patients with Cardiac Syndrome X and its Relationship with Inflamatuar and Oxidative Stress Markers: A Case Control Study Open
Objective: Cardiac syndrome X (CSX) is used to define patients with ischemic chest pain and normal coronary arteries, as revealed by angiography. The etiology of CSX may be associated with extensive coronary microvascular endothelial dysfu…
View article: The relationship between serum vitamin D levels and hematological inflammatory indices in patients with heart failure
The relationship between serum vitamin D levels and hematological inflammatory indices in patients with heart failure Open
The relationship between serum vitamin D levels and hematological inflammatory indices in patients with heart failureH eart failure (HF) is a clinical syndrome that occurs as a result of structural and/or functional abnormalities in the he…
View article: The Effect of HCV-RNA, HCV-Genotype 1b, and Anti-HCV Positivity on Laboratory Parameters
The Effect of HCV-RNA, HCV-Genotype 1b, and Anti-HCV Positivity on Laboratory Parameters Open
Objectives:We aimed to compare the effect of hepatitis C virus (HCV)-RNA, HCV-genotype 1b, and anti-HCV positivity on laboratory parameters in our study.Materials and Methods: HCV-RNA and anti-HCV tests were analyzed from 500 patients and …
View article: Use of Mindray MC-80 digital morphology analyzer’s estimated platelet counts as adjunct to automated hematology analyzer
Use of Mindray MC-80 digital morphology analyzer’s estimated platelet counts as adjunct to automated hematology analyzer Open
Introduction: Automated hematology analyzer platelet counts can be performed using either the impedance (PLT-I) method or the fluorescent nucleic acid staining (PLT-O) method. Estimated platelet counts (PLT-E) can be calculated using a dig…
View article: Protective effects of methylprednisolone in kidney: aortic occlusion-reperfusion model in rats
Protective effects of methylprednisolone in kidney: aortic occlusion-reperfusion model in rats Open
Objectives: Ischemia/reperfusion (I/R) injury is commonly seen in cardiovascular surgery, activates inflammation and causes renal damage. In this experimental study, we aimed to assess the effects of different doses (5 and 30 mg/kg) of met…
View article: Reducing the need for repeating urine drug testing with the gray zone determined by the measurement uncertainty
Reducing the need for repeating urine drug testing with the gray zone determined by the measurement uncertainty Open
Background: On an initial urine screening test for illegal substances, if the concentration of a substance is at or above the determined legislative threshold, it is reported as positive. Repeating testing with the same sample to verify it…
View article: Syndecan-1 as a marker to predict acute kidney injury after isolated coronary artery bypass graft operations
Syndecan-1 as a marker to predict acute kidney injury after isolated coronary artery bypass graft operations Open
This study revealed that elevated preoperative syndecan-1 is associated with acute kidney injury after isolated coronary artery bypass graft accompanied by cardiopulmonary bypass and has prognostic utility independent of other recognized r…
View article: Fibroblast growth factor 23 (Fgf23) levels and their relationship with disease activity, bone mineral density, and radiological damage score in patients with rheumatoid arthritis: a single center case–control study
Fibroblast growth factor 23 (Fgf23) levels and their relationship with disease activity, bone mineral density, and radiological damage score in patients with rheumatoid arthritis: a single center case–control study Open
Background There is limited and conflicting information on Fgf23 levels and their relationship with bone loss and disease activity in rheumatoid arthritis (RA). The aim of this study was to compare Fgf23 levels in RA patients with a health…
View article: The investigation of thiol-disulfide homeostasis in patients with diabetic peripheral neuropathy
The investigation of thiol-disulfide homeostasis in patients with diabetic peripheral neuropathy Open
Objectives: Oxidative stress plays a significant role in the pathogenesis of chronic diabetic complications. Hyperglycemia induced oxidative stress is prominent for the development of diabetic polyneuropathy (PNP). Thiol disulfide homeosta…
View article: Thiol-disulfide homeostasis in children with febrile neutropenia
Thiol-disulfide homeostasis in children with febrile neutropenia Open
Aim: The body’s antioxidant system processes rely on thiol-disulfide equilibrium to function correctly. The purpose of this study was to look into dynamic thiol/disulfide homeostasis (TDH) as an endogenous antioxidant indicator in febrile …
View article: A retrospective study of age‐defined hematologic inflammatory markers related to pediatric COVID‐19 diagnosis
A retrospective study of age‐defined hematologic inflammatory markers related to pediatric COVID‐19 diagnosis Open
Background The aim of this study was to examine age‐related differences in hemogram parameters and hematologic inflammatory markers in pediatric patients with COVID‐19. Methods This retrospective study included children aged 2 months to 18…
View article: Accuracy of Dongjui analyzer for reducing the number of unnecessary urine cultures in an outpatient setting
Accuracy of Dongjui analyzer for reducing the number of unnecessary urine cultures in an outpatient setting Open
Objectives: The purpose of this study was to evaluate the diagnostic performance of the Dongjui DJ-8602 urinary analyzer for reducing the number of unnecessary urine cultures in patients with suspected urinary tract infection (UTI). Method…
View article: Effect of Fresh Gas Flow Rate on Thiol/Disulphide Hemostasis and Ischemia-modified Albumin in Laparoscopic Cholecystectomy
Effect of Fresh Gas Flow Rate on Thiol/Disulphide Hemostasis and Ischemia-modified Albumin in Laparoscopic Cholecystectomy Open
There was no difference between low-flow and high-flow anesthesia during laparoscopic cholecystectomy in terms of hemodynamics or thiol/disulphide homeostasis. Key Words: Low-flow anesthesia, High-flow anesthesia, Thiol/disulphide homeosta…
View article: Clinical, radiological and laboratory features and treatment responses of COVID-19 diseases in pregnant women
Clinical, radiological and laboratory features and treatment responses of COVID-19 diseases in pregnant women Open
Background: SARS-CoV-2 is more contagious than other viruses among populations. Pregnant women
are particularly susceptible to respiratory pathogens and severe pneumonia.
Material and Methods: Thirty-two pregnant women who were diagnosed…
View article: Variation in the rate of diagnosis of childhood acute lymphoblastic leukemia in about to the COVID-19 Pandemic: a single-center study
Variation in the rate of diagnosis of childhood acute lymphoblastic leukemia in about to the COVID-19 Pandemic: a single-center study Open
Background. Greaves delayed infection hypothesis states that acute lymphoblastic leukemia (ALL) in children develops in two critical steps, with the first step (first hit) occurring in utero and the second step (second hit) occurring in th…
View article: Correlation between systemic immune-inflammation index and routine hemogram-related inflammatory markers in the prognosis of retinopathy of prematurity
Correlation between systemic immune-inflammation index and routine hemogram-related inflammatory markers in the prognosis of retinopathy of prematurity Open
Purpose: To evaluate the prognostic potential of systemic inflammatory index in the course of retinopathy of prematurity (ROP). Methods: This is a retrospective case-control study. 303 infants with a gestational age of ≤35 weeks were scree…
View article: The effect of bilateral and unilateral knee arthroplasty under regional anesthesia on ischaemia-modified albumin and thiol/disulphide homeostasis
The effect of bilateral and unilateral knee arthroplasty under regional anesthesia on ischaemia-modified albumin and thiol/disulphide homeostasis Open
Knee arthroplasty and ischaemia reperfusionThe effect of bilateral and unilateral knee arthroplasty under regional anesthesia on ischaemia-modified albumin and thiol
View article: The Effects of Aortic Clamping Strategy on Myocardial Protection and Early Postoperative Outcomes During Coronary Artery Bypass Grafting Operations
The Effects of Aortic Clamping Strategy on Myocardial Protection and Early Postoperative Outcomes During Coronary Artery Bypass Grafting Operations Open
Background: The purpose of the present study was to compare the effects of two different clamping strategies for the construction of the proximal aortocoronary anastomoses on myocardial protection and postoperative outcomes during coronary…
View article: Do initial hematologic indices predict the severity of COVID-19 patients?
Do initial hematologic indices predict the severity of COVID-19 patients? Open
These data showed that age, initial NLR, PLR, and LYM × PLT were associated with the severity of COVID-19 disease and patients’ need for the ICU. Therefore, initial hemogram parameters may be essential to predict the prognosis of COVID-19 …
View article: Relationship between Helicobacter pylori and thiol-disulfide homeostasis: A prospective observational study
Relationship between Helicobacter pylori and thiol-disulfide homeostasis: A prospective observational study Open
Aim: Helicobacter pylori (HP) infection causes inflammation and oxidative stress at a cellular level. In the present study, we aimed to evaluate the possible relationship between HP and thiol-disulfide homeostasis (TDH), a novel indicator …
View article: Effect of serum osmolality on 6-year survival rates in patients with acute myocardial
Effect of serum osmolality on 6-year survival rates in patients with acute myocardial Open
Aim: In the present study, we aimed to evaluate the potential relationship between serum osmolality and mortality rates in a six year of follow-up in patients with a history of acute myocardial infarction. Material and Methods: A retrospec…
View article: Mesane tümörlerinde hemoglobin-redcell distrubition width oranı (Hb/RDW) ve neutrophil-lymphocyte oranı (NLR) lamina propria invazyonunu tahmin etmede kullanılabilir mi?
Mesane tümörlerinde hemoglobin-redcell distrubition width oranı (Hb/RDW) ve neutrophil-lymphocyte oranı (NLR) lamina propria invazyonunu tahmin etmede kullanılabilir mi? Open
Objective: To investigate the importance of the Hemoglobin/Red cell distribution width ratio (Hb/RDW) and Neutrophil/Lymphocyte ratio (NLR) in predicting bladder lamina propria invasion before transurethral resection in non-muscular invasi…
View article: Evaluation of Sigma value and quality goal index for brain natriuretic peptide test
Evaluation of Sigma value and quality goal index for brain natriuretic peptide test Open
Evaluation of sigma value and quality goal index for brain natriuretic peptide testT he b-type or brain natriuretic peptide (BNP) is a member of the natriuretic peptide family that is involved in many biological events in the body, includi…
View article: Vitamin D and thiol-disulfide homeostasis levels in postmenopausal women with overactive bladder syndrome
Vitamin D and thiol-disulfide homeostasis levels in postmenopausal women with overactive bladder syndrome Open
Background: This study aimed to find a relationship between vitamin D concentration and thiol-disulfide homeostasis in the pathophysiology of overactive bladder (OAB) syndrome in postmenopausal women. Methods: A total of 76 postmenopausal …
View article: Comparison of Serum Biochemical and Haematological Analyses in Patients with Age-Related Macular Degeneration and Diabetic Retinopathy
Comparison of Serum Biochemical and Haematological Analyses in Patients with Age-Related Macular Degeneration and Diabetic Retinopathy Open
We evaluated biochemical analysis results with the aim of discovering serum levels that have possible effects and differences on age-related macular degeneration (AMD) and diabetic retinopathy (DRP).
A retrospective case-control study was…