Yasmeen Rashid
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View article: Detection and identification of Naegleria species along with Naegleria fowleri in the tap water samples
Detection and identification of Naegleria species along with Naegleria fowleri in the tap water samples Open
View article: Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action
Discovery of the bacterial HslV protease activators as lead molecules with novel mode of action Open
The HslVU enzyme complex, a proteasomal analog found in bacteria, consists of two components, i.e., the HslV protease and the HslU ATPase. These proteins come together to form a functional enzyme complex, where the C-terminal helix of each…
View article: Molecular Docking: An Insight from Drug Discovery to Drug Repurposing Approach
Molecular Docking: An Insight from Drug Discovery to Drug Repurposing Approach Open
The impact of computer-aided drug designing in the field of medicinal chemistry has created a boon in the drug discovery process. Molecular docking is an integral part of bioinformatics that deals with protein-ligand interactions, binding …
View article: Correction: Exploring the extrachromosomal plasmid rDNA of Naegleria fowleri AY27 genotype II: a human brain-eating amoeba via highthroughput sequencing
Correction: Exploring the extrachromosomal plasmid rDNA of Naegleria fowleri AY27 genotype II: a human brain-eating amoeba via highthroughput sequencing Open
View article: Exploring the extrachromosomal plasmid rDNA of Naegleria fowleri AY27 genotype II: A human brain-eating amoeba via high-throughput sequencing
Exploring the extrachromosomal plasmid rDNA of Naegleria fowleri AY27 genotype II: A human brain-eating amoeba via high-throughput sequencing Open
View article: Insights into genome evolution, pan-genome, and phylogenetic implication through mitochondrial genome sequence of Naegleria fowleri species
Insights into genome evolution, pan-genome, and phylogenetic implication through mitochondrial genome sequence of Naegleria fowleri species Open
View article: Naegleria fowleri from Pakistan Has Type-2 Genotype
Naegleria fowleri from Pakistan Has Type-2 Genotype Open
Background: Primary amoebic meningoencephalitis (PAM) is an acute and fulminant CNS infection caused by Naegleria fowleri. Recreational activities and ritual ablution with contaminated warm fresh water are the main reason of PAM. Pakistan …
View article: In-silico three dimensional structure prediction of important Neisseria meningitidis proteins.
In-silico three dimensional structure prediction of important Neisseria meningitidis proteins. Open
Pathogenic bacteria Neisseria meningitidis cause serious infection i.e. meningitis (infection of the brain) worldwide. Among five pathogenic serogroups, serogroup B causes life threatening illness as there is no effective vaccine available…
View article: Identification and structural investigation of potential novel drug candidates against lethal human pathogen.
Identification and structural investigation of potential novel drug candidates against lethal human pathogen. Open
Neisseria meningtidis is responsible for causing meningococcal meningitis along with acute septicaemia in human beings. Functional genomics strategies proved cruciality of certain genes/proteins in Neisseria meningitidis pathogenesis. Duri…
View article: Self-Redirection of Metabolic Flux toward Squalene and Ethanol Pathways by Engineered Yeast
Self-Redirection of Metabolic Flux toward Squalene and Ethanol Pathways by Engineered Yeast Open
We have previously reported that squalene overproducing yeast self-downregulate the expression of the ethanol pathway (non-essential pathway) to divert the metabolic flux to the squalene pathway. In this study, the effect of co-production …
View article: Homology modeling-based structure prediction of pathogenic factors of Neisseria meningitidis
Homology modeling-based structure prediction of pathogenic factors of Neisseria meningitidis Open
Pathogenic bacteria Neisseria meningitidis cause serious infection i.e. meningitis (infection of the brain) worldwide. Among five pathogenic serogroups, serogroups B causes life threatening illness as there is no effective vaccine availabl…