Yasmin Aziz
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View article: Neuroimaging Predictors of Futile Recanalization in Anterior Circulation Stroke: A Systematic Review and Meta-Analysis
Neuroimaging Predictors of Futile Recanalization in Anterior Circulation Stroke: A Systematic Review and Meta-Analysis Open
AIS: Acute Ischemic Stroke; CCR: Cerebral Collateral Recycle; EVT: Endovascular Thrombectomy; FR: Futile Recanalization; HIR: Hypoperfusion Intensity Ratio; LVO: Large Vessel Occlusion; MT: Mechanical Thrombectomy; rCBV: Relative Cerebral …
View article: Fibromuscular Dysplasia and Spontaneous Cervical Artery Dissection
Fibromuscular Dysplasia and Spontaneous Cervical Artery Dissection Open
Importance Fibromuscular dysplasia (FMD) is found in 6 to 14% of patients with spontaneous cervical artery dissection (SCEAD) and may be associated with recurrent SCEAD. Objective To evaluate the correlates of FMD in patients with SCEAD an…
View article: Extensive ischemic change on stroke presentation is uncommon: A population-based study
Extensive ischemic change on stroke presentation is uncommon: A population-based study Open
In our population, most patients presenting within 24 hours of LKN had ASPECTS ≥6. Even in patients with NIHSS ≥6, only 14 % of patients presenting in the extended time window had ASPECTS <6. These results can inform resource utilization a…
View article: MORTALIDADE POR LEUCEMIA LINFOBLÁSTICA AGUDA NO BRASIL ‒ UMA ANÁLISE EPIDEMIOLÓGICA
MORTALIDADE POR LEUCEMIA LINFOBLÁSTICA AGUDA NO BRASIL ‒ UMA ANÁLISE EPIDEMIOLÓGICA Open
View article: Intracranial Occlusion in Cryptogenic Stroke Is Not Predictive of Recurrent Ischemic Stroke: A Propensity‐Score Matched Analysis of the Cardiac Abnormalities in Stroke Prevention and Risk of Recurrence Study
Intracranial Occlusion in Cryptogenic Stroke Is Not Predictive of Recurrent Ischemic Stroke: A Propensity‐Score Matched Analysis of the Cardiac Abnormalities in Stroke Prevention and Risk of Recurrence Study Open
Background Intracranial occlusions in embolic stroke of undetermined source are histopathologically similar to cardiac sources of embolism. Whether patients with embolic stroke of undetermined source and intracranial occlusion benefit from…
View article: Prolonged venous transit - where venous outflow meets financial outflow: a cost analysis
Prolonged venous transit - where venous outflow meets financial outflow: a cost analysis Open
View article: Microstructural and microvascular features of white matter hyperintensities and their association with small vessel disease markers
Microstructural and microvascular features of white matter hyperintensities and their association with small vessel disease markers Open
View article: Psychosocial Stress and Risk for Intracerebral Hemorrhage in the ERICH (Ethnic/Racial Variations of Intracerebral Hemorrhage) Study
Psychosocial Stress and Risk for Intracerebral Hemorrhage in the ERICH (Ethnic/Racial Variations of Intracerebral Hemorrhage) Study Open
Background Intracerebral hemorrhage (ICH) carries a 30‐day mortality rate of 40% to 50% and a high burden of disability. Prior studies found that psychosocial stressors are associated with hypertension, ischemic stroke, and important racia…
View article: Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion
Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion Open
Background Acute ischaemic stroke (AIS) is a leading cause of mortality and disability globally, with volume contracted state (VCS), as indicated by an elevated blood urea nitrogen to creatinine (BUN/Cr) ratio, potentially influencing outc…
View article: Circle of Willis Variants and Their Association with Outcome after Successful Revascularization of Anterior Large Vessel Occlusion
Circle of Willis Variants and Their Association with Outcome after Successful Revascularization of Anterior Large Vessel Occlusion Open
CoW variants are associated with functional and mortality outcomes in patients treated with EVT for anterior circulation large vessel occlusion. Further research is needed to determine how CoW vessel anatomy may impact clinical assessment,…
View article: Prolonged Venous Transit on Perfusion Imaging Is Associated with Longer Lengths of Stay in Acute Large Vessel Occlusions
Prolonged Venous Transit on Perfusion Imaging Is Associated with Longer Lengths of Stay in Acute Large Vessel Occlusions Open
In successfully reperfused large vessel occlusion strokes, PVT+ was associated with an additional 2 days of hospital stay on average compared with PVT- patients, when adjusting for other clinical covariables. This simple, novel imaging met…
View article: Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke
Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke Open
In patients with anterior circulation DMVO, a higher CBV index on pretreatment CTP is an independent predictor of excellent functional outcomes at 90 days. These findings suggest that CTP parameters, particularly the CBV index, may be usef…
View article: Role of Hypoperfusion Intensity Ratio in Vessel Occlusions: A Review on Safety and Clinical Outcomes
Role of Hypoperfusion Intensity Ratio in Vessel Occlusions: A Review on Safety and Clinical Outcomes Open
The hypoperfusion intensity ratio (HIR) is a quantitative metric used in vascular occlusion imaging to evaluate the extent of brain tissue at risk due to hypoperfusion. Defined as the ratio of tissue volume with a time-to-maximum (Tmax) of…
View article: Perfusion Abnormalities on 24-Hour Perfusion Imaging in Patients With Complete Endovascular Reperfusion
Perfusion Abnormalities on 24-Hour Perfusion Imaging in Patients With Complete Endovascular Reperfusion Open
BACKGROUND: Perfusion abnormalities in the infarct and salvaged penumbra have been proposed as a potential reason for poor clinical outcome (modified Rankin Scale score >2) despite complete angiographic reperfusion (Thrombolysis in Cerebra…
View article: Predictors of Stroke Recurrence After Initial Diagnosis of Cervical Artery Dissection
Predictors of Stroke Recurrence After Initial Diagnosis of Cervical Artery Dissection Open
Objective Patients with cervical artery dissection (CAD) are at increased ischemic stroke risk. We aimed to identify characteristics that are associated with increased risk of ischemic stroke following initial presentation of CAD and to ev…
View article: Clinical Trial Exclusion Criteria Affect Trial Inclusivity by Race and Sex
Clinical Trial Exclusion Criteria Affect Trial Inclusivity by Race and Sex Open
View article: Prevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis: Analysis of ACTION-CVT
Prevalence and Associations of Dural Arteriovenous Fistulae in Cerebral Venous Thrombosis: Analysis of ACTION-CVT Open
Dural arteriovenous fistulae (DAVFs) represent approximately 10% of all intracranial vascular malformations 1 with an incidence of 0.16-1.04per 100,000 person-years. 2,3Prior studies identified an association between cerebral venous thromb…
View article: First‐Line Treatment of Symptomatic Subocclusive Large‐Vessel Stroke: Results of a Nationwide StrokeNet Survey
First‐Line Treatment of Symptomatic Subocclusive Large‐Vessel Stroke: Results of a Nationwide StrokeNet Survey Open
Background Limited evidence is available for the treatment of acute symptomatic subocclusive lesions in ischemic stroke. We sought to identify current treatment patterns of stroke teams at academic health centers. Methods We conducted an e…
View article: Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study
Racial Disparities in Blood Pressure at Time of Acute Ischemic Stroke Presentation: A Population Study Open
Background Hypertension is a stroke risk factor with known disparities in prevalence and management between Black and White patients. We sought to identify if racial differences in presenting blood pressure (BP) during acute ischemic strok…
View article: Factors Associated With Premature Termination of Hyperacute Stroke Trials: A Review
Factors Associated With Premature Termination of Hyperacute Stroke Trials: A Review Open
Background We performed a review of acute stroke trials to determine features associated with premature termination of trial enrollment, defined by the authors as not meeting preplanned sample size. Methods and Results MEDLINE was searched…
View article: Incidence and clinical outcomes of perforations during mechanical thrombectomy for medium vessel occlusion in acute ischemic stroke: A retrospective, multicenter, and multinational study
Incidence and clinical outcomes of perforations during mechanical thrombectomy for medium vessel occlusion in acute ischemic stroke: A retrospective, multicenter, and multinational study Open
Background: Mechanical thrombectomy (MT) has revolutionized the treatment of acute ischemic stroke (AIS) due to large vessel occlusion (LVO), but its efficacy and safety in medium vessel occlusion (MeVO) remain less explored. This multicen…
View article: Asymptomatic Intracerebral Hemorrhage Following Endovascular Stroke Therapy Is Not Benign: A Systematic Review and Meta‐Analysis
Asymptomatic Intracerebral Hemorrhage Following Endovascular Stroke Therapy Is Not Benign: A Systematic Review and Meta‐Analysis Open
Background Asymptomatic intracerebral hemorrhage (aICH) occurs in approximately 35% of patients with acute ischemic stroke after endovascular thrombectomy. Unlike symptomatic ICH, studies evaluating the effect of aICH on outcomes have been…
View article: Intravenous Thrombolysis to Dissolve Acute Stroke Thrombi: Reflections on the Past Decade
Intravenous Thrombolysis to Dissolve Acute Stroke Thrombi: Reflections on the Past Decade Open
View article: First pass effect as an independent predictor of functional outcomes in medium vessel occlusions: An analysis of an international multicenter study
First pass effect as an independent predictor of functional outcomes in medium vessel occlusions: An analysis of an international multicenter study Open
Introduction: First pass effect (FPE), achievement of complete recanalization (mTICI 2c/3) with a single pass, is a significant predictor of favorable outcomes for endovascular treatment (EVT) in large vessel occlusion stroke (LVO). Howeve…
View article: History of obstructive sleep apnea associated with incident cognitive impairment in white but not black individuals in a US national cohort study
History of obstructive sleep apnea associated with incident cognitive impairment in white but not black individuals in a US national cohort study Open
View article: Enhancing Enrollment in Acute Stroke Trials: Current State and Consensus Recommendations
Enhancing Enrollment in Acute Stroke Trials: Current State and Consensus Recommendations Open
The Stroke Treatment Academic Industry Roundtable (STAIR) convened a session and workshop regarding enrollment in acute stroke trials during the STAIR XII meeting on March 22, 2023. This forum brought together stroke physicians and researc…
View article: Aspiration Versus Stent‐Retriever as First‐Line Endovascular Therapy Technique for Primary Medium and Distal Intracranial Occlusions: A Propensity‐Score Matched Multicenter Analysis
Aspiration Versus Stent‐Retriever as First‐Line Endovascular Therapy Technique for Primary Medium and Distal Intracranial Occlusions: A Propensity‐Score Matched Multicenter Analysis Open
Background For acute proximal intracranial artery occlusions, contact aspiration may be more effective than stent‐retriever for first‐line reperfusion therapy. Due to the lack of data regarding medium vessel occlusion thrombectomy, we eval…
View article: Hyperglycemia, Ischemic Lesions, and Functional Outcomes After Intracerebral Hemorrhage
Hyperglycemia, Ischemic Lesions, and Functional Outcomes After Intracerebral Hemorrhage Open
Background Ischemic lesions observed on diffusion‐weighted imaging (DWI) magnetic resonance imaging are associated with poor outcomes after intracerebral hemorrhage (ICH). We evaluated the association between hyperglycemia, ischemic lesion…
View article: Using Epidemiological Data to Inform Clinical Trial Feasibility Assessments: A Case Study
Using Epidemiological Data to Inform Clinical Trial Feasibility Assessments: A Case Study Open
Background: Clinical trial enrollment and completion is challenging, with nearly half of all trials not being completed or not completed on time. In 2014, the National Institutes of Health StrokeNet in collaboration with stroke epidemiolog…
View article: Changing Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis–Related Stroke, 2005–2015
Changing Trends in Demographics, Risk Factors, and Clinical Features of Patients With Infective Endocarditis–Related Stroke, 2005–2015 Open
BACKGROUND AND OBJECTIVES: There is a rising incidence of infective endocarditis-related stroke (IERS) in the United States attributed to the opioid epidemic. A contemporary epidemiologic description is necessary to understand the impact o…