Yasmin Escobedo-Lozoya
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View article: Cortical Slice Culture Protocol for Rodent Brain v1
Cortical Slice Culture Protocol for Rodent Brain v1 Open
This protocol details a method for preparing and culturing organotypic cortical slices from mouse neocortex, using an interface method such as that first described in Stoppini et al., 1991, emphasizing sterile techniques for long-term cult…
View article: Prolonged Activity Deprivation Causes Pre- and Postsynaptic Compensatory Plasticity at Neocortical Excitatory Synapses
Prolonged Activity Deprivation Causes Pre- and Postsynaptic Compensatory Plasticity at Neocortical Excitatory Synapses Open
Homeostatic plasticity stabilizes firing rates of neurons, but the pressure to restore low activity rates can significantly alter synaptic and cellular properties. Most previous studies of homeostatic readjustment to complete activity sile…
View article: Progressive Circuit Hyperexcitability in Mouse Neocortical Slice Cultures with Increasing Duration of Activity Silencing
Progressive Circuit Hyperexcitability in Mouse Neocortical Slice Cultures with Increasing Duration of Activity Silencing Open
Forebrain neurons deprived of activity become hyperactive when activity is restored. Rebound activity has been linked to spontaneous seizures in vivo following prolonged activity blockade. Here, we measured the time course of rebound activ…
View article: Progressive circuit hyperexcitability in mouse neocortical slice cultures with increasing duration of activity silencing
Progressive circuit hyperexcitability in mouse neocortical slice cultures with increasing duration of activity silencing Open
Forebrain neurons deprived of activity become hyperactive when activity is restored. Rebound activity has been linked to spontaneous seizures in vivo following prolonged activity blockade. Here we measured the time course of rebound activi…
View article: Prolonged activity-deprivation causes pre- and postsynaptic compensatory plasticity at neocortical excitatory synapses
Prolonged activity-deprivation causes pre- and postsynaptic compensatory plasticity at neocortical excitatory synapses Open
Homeostatic plasticity stabilizes firing rates of neurons, but the pressure to restore low activity rates can significantly alter synaptic and cellular properties. Most previous studies of homeostatic readjustment to complete activity sile…
View article: A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons
A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons Open
Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the greatest number of Pet1-lineage neurons, a predominantly serotonergic group distributed throughout DR subdomains. These neurons collectively regulate diverse phys…
View article: A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe<i>Pet1</i>neurons
A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe<i>Pet1</i>neurons Open
Among the brainstem raphe nuclei, the dorsal raphe nucleus (DR) contains the greatest number of Pet1 -lineage neurons, a predominantly serotonergic group distributed throughout DR subdomains. These neurons collectively regulate diverse phy…