Yasser E. Shahein
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View article: Emerged SARS-CoV-2 intermediate hosts: The missing links from One Health perspective
Emerged SARS-CoV-2 intermediate hosts: The missing links from One Health perspective Open
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019, triggering a worldwide pandemic that presented significant health challenges and financial turmoil for people everywhere. Vaccines and antivirals, inclu…
View article: Mining the secreted and membrane transcriptome of Hyalomma dromedarii ticks for identification of potential protective antigens
Mining the secreted and membrane transcriptome of Hyalomma dromedarii ticks for identification of potential protective antigens Open
View article: Evaluation of physical, chemical, and microbiological characteristics of waste stabilization ponds, Giza, Egypt
Evaluation of physical, chemical, and microbiological characteristics of waste stabilization ponds, Giza, Egypt Open
Wastewater treatment plants (WWTPs) contain a diverse array of microbes, underscoring the need for regular monitoring to ensure treatment efficacy and protect health. However, detailed studies on waste stabilization ponds (WSPs) are scarce…
View article: Molecular screening of piroplasms and Anaplasmataceae agents in Hyalomma dromedarii ticks from camels over different seasons in Egypt
Molecular screening of piroplasms and Anaplasmataceae agents in Hyalomma dromedarii ticks from camels over different seasons in Egypt Open
View article: Monoclonal IgY antibodies: advancements and limitations for immunodiagnosis and immunotherapy applications
Monoclonal IgY antibodies: advancements and limitations for immunodiagnosis and immunotherapy applications Open
Due to their high specificity and scalability, Monoclonal IgY antibodies have emerged as a valuable alternative to traditional polyclonal IgY antibodies. This abstract provides an overview of the production and purification methods of mono…
View article: Altering Escherichia coli envelope integrity by mimicking the lipoprotein RcsF
Altering Escherichia coli envelope integrity by mimicking the lipoprotein RcsF Open
Escherichia coli cell envelope is crucial for stress sensing and signal transduction, mediated by numerous protein–protein interactions to enable adaptation and survival. Interfering with these interactions might affect envelope integrity …
View article: Biomarkers for Hepatocellular Carcinoma: From Origin to Clinical Diagnosis
Biomarkers for Hepatocellular Carcinoma: From Origin to Clinical Diagnosis Open
The incidence of hepatocellular carcinoma (HCC) and HCC-related deaths has increased over the last few decades. There are several risk factors of HCC such as viral hepatitis (B, C), cirrhosis, tobacco and alcohol use, aflatoxin-contaminate…
View article: Comparative assessment of homemade ELISA and lateral flow assay (LFA)in the rapid, specific and sensitive detection of SARS-CoV-2 anti-nucleocapsid protein in sera of Egyptian patients
Comparative assessment of homemade ELISA and lateral flow assay (LFA)in the rapid, specific and sensitive detection of SARS-CoV-2 anti-nucleocapsid protein in sera of Egyptian patients Open
Several diagnostic measures have been employed to precisely detect the SARS-CoV-2 viral infection using viral antigens, nucleic acids, and other serological approaches. The sensitivity and specificity of the serological tests remain a chal…
View article: The first detection of SARS-CoV-2 RNA in urban wastewater in Giza, Egypt
The first detection of SARS-CoV-2 RNA in urban wastewater in Giza, Egypt Open
The new coronavirus (SARS-CoV-2) is a respiratory virus causing coronavirus disease (COVID-19). Individuals with COVID-19 can shed the viral genome in their feces, even if they do not have symptoms, and the virus can be detected in wastewa…
View article: Egyptian cobra (Naja haje haje) venom phospholipase A2: a promising antiviral agent with potent virucidal activity against simian rotavirus and bovine coronavirus
Egyptian cobra (Naja haje haje) venom phospholipase A2: a promising antiviral agent with potent virucidal activity against simian rotavirus and bovine coronavirus Open
Viral infections are linked to a variety of human diseases. Despite the achievements made in drug and vaccine development, several viruses still lack preventive vaccines and efficient antiviral compounds. Thus, developing novel antiviral a…
View article: Epoxy functionalized iron oxide magnetic nanoparticles for catalase enzyme covalent immobilization
Epoxy functionalized iron oxide magnetic nanoparticles for catalase enzyme covalent immobilization Open
An aqueous solution of magnetite (Fe 3 O 4 ) nanoparticles was synthesized using the method of co-precipitation. The nanoparticles were activated with epichlorohydrin for covalently immobilizing the catalase enzyme. The immobilization cond…
View article: Grafted carrageenan: alginate gel beads for catalase enzyme covalent immobilization
Grafted carrageenan: alginate gel beads for catalase enzyme covalent immobilization Open
View article: A review of monoclonal antibodies in COVID-19: Role in immunotherapy, vaccine development and viral detection
A review of monoclonal antibodies in COVID-19: Role in immunotherapy, vaccine development and viral detection Open
The harmful COVID-19 pandemic caused by the SARS-CoV-2 coronavirus imposes the scientific community to develop or find conventional curative drugs, protective vaccines, or passive immune strategies rapidly and efficiently. Passive immunity…
View article: Protein Misfolding, Aggregation, Amyloid Formation in Neurodegenerative Diseases: Latest Therapeutic Approaches for Treating Neurodegenerative Diseases
Protein Misfolding, Aggregation, Amyloid Formation in Neurodegenerative Diseases: Latest Therapeutic Approaches for Treating Neurodegenerative Diseases Open