Yasuhiko Abe
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View article: Helicobacter pylori eradication and gastric cancer prevention in a pooled analysis of large-scale cohort studies in Japan
Helicobacter pylori eradication and gastric cancer prevention in a pooled analysis of large-scale cohort studies in Japan Open
Helicobacter pylori (H. pylori) infection is an established cause of gastric cancer. Although H. pylori eradication is suggested to decrease gastric cancer risk, this has not been fully investigated in general populations. This analysis in…
View article: Age distribution and risk factors for Barrett's esophagus by sex at health check-up settings in Japan
Age distribution and risk factors for Barrett's esophagus by sex at health check-up settings in Japan Open
Background Given the high prevalence of esophageal adenocarcinoma and Barrett's esophagus (BE), a precancerous lesion, among males, it is important to understand the characteristics of BE by sex to develop an effective endoscopic surveilla…
View article: Helicobacter pylori eradication and gastric cancer prevention: Pooled analysis of large-scale cohort studies in Japan
Helicobacter pylori eradication and gastric cancer prevention: Pooled analysis of large-scale cohort studies in Japan Open
Helicobacter pylori (H. pylori) infection is the established cause of gastric cancer. Although H. pylori eradication is suggested to decrease gastric cancer risk, this has not been fully investigated in general populations. This analysis i…
View article: Prevalence and Distribution of Gastric Endoscopy Findings in Non-eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Influence of Atrophic Gastritis
Prevalence and Distribution of Gastric Endoscopy Findings in Non-eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases: Influence of Atrophic Gastritis Open
Objective The impact of Helicobacter pylori infection on gastric endoscopic findings in non-eosinophilic esophagitis eosinophilic gastrointestinal diseases (non-EoE EGIDs) remains unclear. This study investigated the influence of H. pylori…
View article: Young Patient with X-linked Agammaglobulinemia Presents with Advanced Gastric Cancer and Extensive Atrophic Gastritis
Young Patient with X-linked Agammaglobulinemia Presents with Advanced Gastric Cancer and Extensive Atrophic Gastritis Open
X-linked agammaglobulinemia (XLA) is associated with an increased risk of gastrointestinal cancers including gastric cancer (GC). We herein report the case of a 30-year-old male patient with XLA who developed GC and extensive atrophic gast…
View article: Endoscopic and histological risk stratification for gastric cancer using gastric intestinal metaplasia
Endoscopic and histological risk stratification for gastric cancer using gastric intestinal metaplasia Open
Background and Aim Intestinal metaplasia (IM) of the gastric mucosa is strongly associated with the risk of gastric cancer (GC). This study was performed to investigate the usefulness of endoscopic and histological risk stratification for …
View article: Long-term course of untreated asymptomatic esophageal eosinophilia and minimally symptomatic eosinophilic esophagitis
Long-term course of untreated asymptomatic esophageal eosinophilia and minimally symptomatic eosinophilic esophagitis Open
Background and study aims The long-term course of untreated asymptomatic esophageal eosinophilia (aEE) and minimally symptomatic eosinophilic esophagitis (mEoE) are not well understood. This study aimed to clarify this course. Patients and…
View article: Acceptability, Safety, and Feasibility of Transnasal and Peroral Ultrathin Endoscopy Using GAGLESS Mouthpieces: A Prospective Randomized Trial
Acceptability, Safety, and Feasibility of Transnasal and Peroral Ultrathin Endoscopy Using GAGLESS Mouthpieces: A Prospective Randomized Trial Open
For patients in whom there was difficulty in inserting a nasal endoscope, using a GAGLESS mouthpiece rather than a conventional mouthpiece may be more useful in reducing pain.
View article: Impact of the COVID‐19 pandemic on the performance of endoscopy in the Tohoku region of Japan
Impact of the COVID‐19 pandemic on the performance of endoscopy in the Tohoku region of Japan Open
Objectives The whole picture of the disturbance in endoscopy performance caused by the coronavirus disease 2019 (COVID‐19) pandemic in Japan remains to be clarified. Therefore, the Japan Gastroenterological Endoscopy Society‐Tohoku conduct…
View article: Blue light imaging and linked color imaging as a screening mode for esophageal squamous cell carcinoma in high‐risk patients: Multicenter randomized trial
Blue light imaging and linked color imaging as a screening mode for esophageal squamous cell carcinoma in high‐risk patients: Multicenter randomized trial Open
Objectives Blue light imaging (BLI) and linked color imaging (LCI) are superior to conventional white light imaging for detecting esophageal squamous cell carcinoma (ESCC). Hence, we compared their diagnostic performances in ESCC screening…
View article: Small Bowel Endoscopic Features of Eosinophilic Gastroenteritis
Small Bowel Endoscopic Features of Eosinophilic Gastroenteritis Open
Eosinophilic gastroenteritis (EoGE) is a rare digestive disorder characterized by eosinophilic infiltration of the stomach and intestines. In the diagnosis of EoE, it is extremely important to recognize distinctive endoscopic findings and …
View article: Endoscopic Diagnosis of Eosinophilic Esophagitis: Basics and Recent Advances
Endoscopic Diagnosis of Eosinophilic Esophagitis: Basics and Recent Advances Open
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease, characterized by esophageal dysfunction and intense eosinophil infiltration localized in the esophagus. In recent decades, EoE has become a growing concern …
View article: Linked color imaging improves the diagnostic accuracy of eosinophilic esophagitis
Linked color imaging improves the diagnostic accuracy of eosinophilic esophagitis Open
Objectives To assess the usefulness of linked color imaging (LCI), a recently developed image‐enhanced endoscopy technique, in the endoscopic diagnosis of eosinophilic esophagitis (EoE). Methods Thirty white light images (WLIs) and 30 WLI+…
View article: An Unusual Small Bowel Phytobezoar Successfully Resolved by Double-balloon Enteroscopy
An Unusual Small Bowel Phytobezoar Successfully Resolved by Double-balloon Enteroscopy Open
We herein report a very unusual case of small bowel obstruction caused by phytobezoar in a 69-year-old woman who consumed a large amount of bracken. The patient presented with nausea and vomiting. Computed tomography revealed an air-filled…
View article: Small-bowel Capsule Endoscopic Features in Patients with Eosinophilic Gastroenteritis: Three Case Reports
Small-bowel Capsule Endoscopic Features in Patients with Eosinophilic Gastroenteritis: Three Case Reports Open
Eosinophilic gastroenteritis (EGE) is an uncommon disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of secondary causes and presents with a variety of gastrointestinal manifestations. Important…
View article: Characteristics of the gut microbiome profile in obese patients with colorectal cancer
Characteristics of the gut microbiome profile in obese patients with colorectal cancer Open
Background and Aim Obesity affects the gut microbiome, which in turn increases the risk for colorectal cancer. Several studies have shown the mechanisms by which some bacteria may influence the development of colorectal cancer; however, gu…
View article: Long‐term endoscopic surveillance for Barrett's esophagus in Japan: Multicenter prospective cohort study
Long‐term endoscopic surveillance for Barrett's esophagus in Japan: Multicenter prospective cohort study Open
Objects Although a recent study showed the cancer incidence of Barrett's esophagus (BE) to be 1.2%/year in 251 patient‐years in Japan, the long‐term outcomes remain unclear. The present study estimated the cancer risk of BE in Japan using …
View article: Clinical Features of Esophageal Eosinophilia According to Endoscopic Phenotypes
Clinical Features of Esophageal Eosinophilia According to Endoscopic Phenotypes Open
Objective Esophageal eosinophilia (EE), a histological hallmark of eosinophilic esophagitis, is classified into two endoscopic phenotypes: localized and diffuse EE. Our aim was to determine the prevalence of EE localized in the lower esoph…
View article: Cronkhite-Canada Syndrome Associated with Gastric Outlet Obstruction and Membranous Nephropathy: A Case Report and Review of the Literature
Cronkhite-Canada Syndrome Associated with Gastric Outlet Obstruction and Membranous Nephropathy: A Case Report and Review of the Literature Open
A 47-year-old man presented with dysgeusia, anorexia, and diarrhea. An endoscopic evaluation showed widespread gastrointestinal nodular inflammation and polyps. The pathological findings were consistent with Cronkhite-Canada Syndrome (CCS)…
View article: Anomaly Detection Method “Cumulative Sum Detection” for In-Vehicle Networks
Anomaly Detection Method “Cumulative Sum Detection” for In-Vehicle Networks Open
This paper proposes cumulative sum detection, which can detect cyberattacks on Controller Area Network (CAN). Well-known existing attack detection techniques cause false positives and false negatives when there are long delays or early arr…
View article: Accuracy and reliability of novel semi-automated two-dimensional layer specific speckle tracking software for quantifying left ventricular volumes and function
Accuracy and reliability of novel semi-automated two-dimensional layer specific speckle tracking software for quantifying left ventricular volumes and function Open
Mid-myocardial tracking with the novel 2DE strain software provided less bias of LV volumes with high CP values of LVEF and GLS, which suggests that mid-myocardial layer speckle tracking analysis approximates CMR derived LV functional para…
View article: Acidic bile salts induces mucosal barrier dysfunction through <i>let-7a</i> reduction during gastric carcinogenesis after <i>Helicobacter pylori</i> eradication
Acidic bile salts induces mucosal barrier dysfunction through <i>let-7a</i> reduction during gastric carcinogenesis after <i>Helicobacter pylori</i> eradication Open
Gastric cancer (GC) after eradication for Helicobacter pylori (H.pylori) increases, but its carcinogenesis is not elucidated. It is mainly found in acid non-secretion areas (ANA), as mucosal regeneration in acid secretory areas (AA) after …