Yasuko Uchigata
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View article: Effect of a Multifactorial Intervention on Retinopathy in People With Type 2 Diabetes
Effect of a Multifactorial Intervention on Retinopathy in People With Type 2 Diabetes Open
Importance Prevention of diabetic retinopathy is important to keep vision and quality of life. Objective To examine the effects of an intensive multifactorial intervention and hypoglycemia on retinopathy in people with type 2 diabetes. Des…
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View article: Correction: ƩexcessA1C index, the sum of yearly excess HbA1c values during the total period of diabetes, may have the potential to predict retinopathy by a linear regression setting regardless of duration in type 1 diabetes: a subgroup analysis of DCCT/EDIC data
Correction: ƩexcessA1C index, the sum of yearly excess HbA1c values during the total period of diabetes, may have the potential to predict retinopathy by a linear regression setting regardless of duration in type 1 diabetes: a subgroup analysis of DCCT/EDIC data Open
View article: ƩexcessA1C index, the sum of yearly excess HbA1c values during the total period of diabetes, may have the potential to predict retinopathy by a linear regression setting regardless of duration in type 1 diabetes: a subgroup analysis of DCCT/EDIC data
ƩexcessA1C index, the sum of yearly excess HbA1c values during the total period of diabetes, may have the potential to predict retinopathy by a linear regression setting regardless of duration in type 1 diabetes: a subgroup analysis of DCCT/EDIC data Open
View article: Direct Oral Anticoagulants Affect Activated Clotting Time During and Bleeding Events After Percutaneous Coronary Intervention
Direct Oral Anticoagulants Affect Activated Clotting Time During and Bleeding Events After Percutaneous Coronary Intervention Open
Background Inappropriately high activated clotting time (ACT) during percutaneous coronary intervention (PCI) is associated with an increased risk of bleeding events. However, whether the prescription of direct oral anticoagulants (DOAC) a…
View article: Risk of fetal undergrowth in the management of gestational diabetes mellitus in Japan
Risk of fetal undergrowth in the management of gestational diabetes mellitus in Japan Open
Aims/Introduction In Japan, the increasing frequency of underweight among women of reproductive age and the accompanying increase in the rate of low birth weight (LBW) are social issues. The study aimed to establish a prospective registry …
View article: Update information on type 1 diabetes in children/adolescents and adults
Update information on type 1 diabetes in children/adolescents and adults Open
In 2000, the world's age-adjusted prevalence of type 1 diabetes with onset under 15 years was reported using data from 1990 to 19941. The lowest incidence rate (/105 person-years) was 0.1 in China and Venezuela, and the highest was 36.8 in…
View article: Factors associated with hypoglycemia unawareness and severe hypoglycemia in type 1 diabetes mellitus patients
Factors associated with hypoglycemia unawareness and severe hypoglycemia in type 1 diabetes mellitus patients Open
Aims/Introduction Several factors are associated with hypoglycemia unawareness and severe hypoglycemia, but few large studies have analyzed Japanese patients with type 1 diabetes. The aim of this study was to analyze the risk factors for h…
View article: REGN-COV2 antibody cocktail in patients with SARS-CoV-2: Observational study from a single institution in Japan
REGN-COV2 antibody cocktail in patients with SARS-CoV-2: Observational study from a single institution in Japan Open
This study shows that treatment with the REGN-COV2 antibody cocktail is safe and beneficial in patients at a risk of developing severe COVID-19.
View article: Is Chronic Kidney Disease Affecting the Postoperative Complications of Vitrectomy for Proliferative Diabetic Retinopathy?
Is Chronic Kidney Disease Affecting the Postoperative Complications of Vitrectomy for Proliferative Diabetic Retinopathy? Open
Chronic kidney disease (CKD) is a well-known risk factor for postoperative complications in several surgical fields. However, although prevalent among diabetic candidates for vitrectomy, the effect of CKD on vitrectomy outcomes remains unc…
View article: Universal testing for SARS-CoV-2 infection on admission among hospitalized emergency patients: A survey report from a single facility in Tokyo
Universal testing for SARS-CoV-2 infection on admission among hospitalized emergency patients: A survey report from a single facility in Tokyo Open
View article: Recurrent Hypoglycemia Due to a High Titer of Insulin Antibody in Response to Exogenous Insulin Administration in Two Cases of Type 1 Diabetes
Recurrent Hypoglycemia Due to a High Titer of Insulin Antibody in Response to Exogenous Insulin Administration in Two Cases of Type 1 Diabetes Open
In the first case, a 60-year-old man who was using continuous subcutaneous insulin infusion (CSII), developed recurrent hypoglycemia due to insulin antibodies. This is the first report of such a case using CSII. In the second case, a 70-ye…
View article: Psychological Effects on Healthcare Workers during the COVID-19 Outbreak: A Single-center Study at a Tertiary Hospital in Tokyo, Japan
Psychological Effects on Healthcare Workers during the COVID-19 Outbreak: A Single-center Study at a Tertiary Hospital in Tokyo, Japan Open
Objective The present study analyzed the psychological status of healthcare workers in Japan and the influencing factors during the 2019 coronavirus disease pandemic. Methods An online survey was conducted from July 22 to August 21, 2020. …
View article: Usefulness of glycated albumin as a predictor of mortality in chronic hemodialysis patients with diabetes: a multi-center, prospective cohort study
Usefulness of glycated albumin as a predictor of mortality in chronic hemodialysis patients with diabetes: a multi-center, prospective cohort study Open
Background The association of glycated albumin (GA) with mortality is unclear in chronic hemodialysis patients with diabetes. We investigated the usefulness of GA by comparing it with hemoglobin A1c (HbA1c) in this patient population. Rese…
View article: Efficacy and safety of dapagliflozin in Japanese patients with inadequately controlled type 1 diabetes (DEPICT‐5): 52‐week results from a randomized, open‐label, phase III clinical trial
Efficacy and safety of dapagliflozin in Japanese patients with inadequately controlled type 1 diabetes (DEPICT‐5): 52‐week results from a randomized, open‐label, phase III clinical trial Open
Aims To investigate the safety and tolerability of 5 and 10 mg dapagliflozin added to insulin therapy over 52 weeks in Japanese patients with inadequately controlled type 1 diabetes mellitus (T1DM). Materials and methods This randomized, o…
View article: Vitreous hemorrhage in diabetes patients with proliferative diabetic retinopathy undergoing hemodialysis
Vitreous hemorrhage in diabetes patients with proliferative diabetic retinopathy undergoing hemodialysis Open
Aims/Introduction For diabetes patients undergoing hemodialysis, vitreous hemorrhage seems to be a hemodialysis‐induced hemorrhagic complication because of the effect of systemic anticoagulation. However, it is unclear whether hemodialysis…
View article: Clinical and genetic characteristics of people with type 1 diabetes who have discrepancies in titers of anti‐glutamic acid decarboxylase antibody measured by radioimmunoassay and enzyme‐linked immunosorbent assay
Clinical and genetic characteristics of people with type 1 diabetes who have discrepancies in titers of anti‐glutamic acid decarboxylase antibody measured by radioimmunoassay and enzyme‐linked immunosorbent assay Open
Aims/Introduction The aim of the present study was to compare the clinical and genetic characteristics between people with type 1 diabetes who were positive and negative for autoantibodies against glutamic acid decarboxylase ( GADA ) measu…
View article: Clinical background of Japanese patients with type 1 diabetes mellitus who have received insulin therapy for 50 years or longer
Clinical background of Japanese patients with type 1 diabetes mellitus who have received insulin therapy for 50 years or longer Open
View article: Rapid increase in the incidence of end-stage renal disease in patients with type 1 diabetes having HbA1c 10% or higher for 15 years
Rapid increase in the incidence of end-stage renal disease in patients with type 1 diabetes having HbA1c 10% or higher for 15 years Open
The incidence of end-stage renal disease (ESRD) in Japanese patients with type 1 diabetes mellitus (T1DM) was investigated regarding the association between mean HbA1c values during follow-up and the duration of follow-up/illness. The stud…
View article: Genome-Wide Association Study Confirming a Strong Effect of HLA and Identifying Variants in<i>CSAD/lnc-ITGB7-1</i>on Chromosome 12q13.13 Associated With Susceptibility to Fulminant Type 1 Diabetes
Genome-Wide Association Study Confirming a Strong Effect of HLA and Identifying Variants in<i>CSAD/lnc-ITGB7-1</i>on Chromosome 12q13.13 Associated With Susceptibility to Fulminant Type 1 Diabetes Open
The first genome-wide association study of fulminant type 1 diabetes was performed in Japanese individuals. As previously reported using a candidate gene approach, a strong association was observed with multiple single nucleotide polymorph…
View article: The still persistent stigma around diabetes: is there something we can do to make it disappear?
The still persistent stigma around diabetes: is there something we can do to make it disappear? Open
View article: Serum lipid management in patients with type 1 and type 2 diabetes: a hospital-based cohort study
Serum lipid management in patients with type 1 and type 2 diabetes: a hospital-based cohort study Open
View article: Characteristics and clinical course of type 1 diabetes mellitus related to anti-programmed cell death-1 therapy
Characteristics and clinical course of type 1 diabetes mellitus related to anti-programmed cell death-1 therapy Open
View article: Investigation of Clinical Factors Related To Diabetic Vascular Endothelial Function Using Reactive Hyperemia Peripheral Arterial Tonometry
Investigation of Clinical Factors Related To Diabetic Vascular Endothelial Function Using Reactive Hyperemia Peripheral Arterial Tonometry Open
Vascular endothelial function can be evaluated based on reactive hyperemia peripheral arterial tonometry (RH-PAT). This information can be used to perform appropriate risk assessments and therapeutic interventions.
View article: Diffusion-weighted magnetic resonance imaging in the pancreas of fulminant type 1 diabetes
Diffusion-weighted magnetic resonance imaging in the pancreas of fulminant type 1 diabetes Open
View article: Renal function after intravitreal administration of vascular endothelial growth factor inhibitors in patients with diabetes and chronic kidney disease
Renal function after intravitreal administration of vascular endothelial growth factor inhibitors in patients with diabetes and chronic kidney disease Open
The present study aimed to determine whether intravitreal administration of vascular endothelial growth factor inhibitors is associated with deterioration of renal function, as seen with systemic administration, in patients with diabetes a…
View article: The incidences of and risk factors for severe retinopathy requiring photocoagulation and albuminuria in Japanese patients with childhood-onset type 1 diabetes
The incidences of and risk factors for severe retinopathy requiring photocoagulation and albuminuria in Japanese patients with childhood-onset type 1 diabetes Open
View article: Creation and Transplantation of an Adipose-derived Stem Cell (ASC) Sheet in a Diabetic Wound-healing Model
Creation and Transplantation of an Adipose-derived Stem Cell (ASC) Sheet in a Diabetic Wound-healing Model Open
Artificial skin has achieved considerable therapeutic results in clinical practice. However, artificial skin treatments for wounds in diabetic patients with impeded blood flow or with large wounds might be prolonged. Cell-based therapies h…
View article: Role of vitamin D in energy and bone metabolism in postmenopausal women with type 2 diabetes mellitus: A 6‐month follow‐up evaluation
Role of vitamin D in energy and bone metabolism in postmenopausal women with type 2 diabetes mellitus: A 6‐month follow‐up evaluation Open
Aims/Introduction Resting energy expenditure was associated with a serum bone turnover marker in postmenopausal women with type 2 diabetes (T2DMPW) in the present cross‐sectional study. To clarify the fundamental pathological factor for th…
View article: Xenogeneic transplantation of human adipose-derived stem cell sheets accelerate angiogenesis and the healing of skin wounds in a Zucker Diabetic Fatty rat model of obese diabetes
Xenogeneic transplantation of human adipose-derived stem cell sheets accelerate angiogenesis and the healing of skin wounds in a Zucker Diabetic Fatty rat model of obese diabetes Open