Yong Feng
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View article: Periodontal-Orthodontic Combined Therapy For Mandibular Anterior Gingival Recession
Periodontal-Orthodontic Combined Therapy For Mandibular Anterior Gingival Recession Open
Introduction: A case of gingival recession and labial bone augmentation in mandibular anterior teeth under combined periodontal-orthodontic treatment. Case description: The patient is a 36-year-old male with gingival recession in the mandi…
View article: Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice
Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice Open
The effects of nicotine on aging‐related motor and cognitive decline remain controversial due to limited empirical evidence. Here, mice are permitted to orally consume nicotine over a 22‐month period and observed attenuated motor decline w…
View article: ApoE Inhibits the Progression of Glioma by Activating Immune Function
ApoE Inhibits the Progression of Glioma by Activating Immune Function Open
Glioma, marked by a low mutational burden, low immunogenicity, high heterogeneity, and the challenges posed by the blood–brain barrier, continues to be a major hurdle in neuro‐oncology. Current research underscores the necessity for more e…
View article: Lipidomic Profiling Reveals HSD17B13 Deficiency-Associated Dysregulated Hepatic Phospholipid Metabolism in Aged Mice
Lipidomic Profiling Reveals HSD17B13 Deficiency-Associated Dysregulated Hepatic Phospholipid Metabolism in Aged Mice Open
Objectives: HSD17B13 (17β-hydroxysteroid dehydrogenase 13), a lipid droplet-associated enzyme, has emerged as a key regulator of hepatic lipid metabolism and a potential therapeutic target for metabolic-associated fatty liver disease (MAFL…
View article: Association Between Metabolic Dysfunction and Gallstone Disease in U.S. Adults: An Analysis of the National Health and Nutrition Examination Survey
Association Between Metabolic Dysfunction and Gallstone Disease in U.S. Adults: An Analysis of the National Health and Nutrition Examination Survey Open
Objectives Gallstones affect a significant proportion of U.S. adults and can cause serious complications. We aimed to investigate the association between gallstone disease and common metabolic disorders in a nationally representative sampl…
View article: Modeling of auditory neuropathy spectrum disorders associated with the TEME43 variant reveals impaired gap junction function of iPSC-derived glia-like support cells
Modeling of auditory neuropathy spectrum disorders associated with the TEME43 variant reveals impaired gap junction function of iPSC-derived glia-like support cells Open
Auditory neuropathy spectrum disorder (ANSD) is an auditory dysfunction disorder characterized by impaired speech comprehension. Its etiology is complex and can be broadly categorized into genetic and non-genetic factors. TMEM43 mutation i…
View article: Exploring the Key Mapk Cascade Genes Involved in Cassava Immune Response to Xanthomonas Phaseoli Pv. Manihotis
Exploring the Key Mapk Cascade Genes Involved in Cassava Immune Response to Xanthomonas Phaseoli Pv. Manihotis Open
View article: The Impact of Physical Exercise on the Mental Health of College Students
The Impact of Physical Exercise on the Mental Health of College Students Open
View article: Analysis of Differences in Physical Fitness Among College Students in Physical Health Testing
Analysis of Differences in Physical Fitness Among College Students in Physical Health Testing Open
View article: Association between tinnitus and hearing impairment among older adults with age-related hearing loss: a multi-center cross-sectional study
Association between tinnitus and hearing impairment among older adults with age-related hearing loss: a multi-center cross-sectional study Open
Objective The relationship between tinnitus in the elderly with hearing loss remains elusive. This study aimed to reveal the association between tinnitus and hearing impairment among older adults with age-related hearing loss (ARHL). Metho…
View article: Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along the cochlear axis
Spatiotemporal transcriptomic analyses reveal molecular gradient patterning during development and the tonotopic organization along the cochlear axis Open
While cochlear tonotopic organization is essential for sound frequency discrimination, the spatiotemporal molecular programs shaping this architecture remain unresolved. Here, we integrate spatiotemporal transcriptomics (E17.5-P8-adult) wi…
View article: ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity
ABCC1 deficiency potentiated noise-induced hearing loss in mice by impairing cochlear antioxidant capacity Open
View article: Biological effect of ETV4 and the underlying mechanism of its regulatory effect on epithelial‑mesenchymal transition in intrahepatic cholangiocarcinoma cells
Biological effect of ETV4 and the underlying mechanism of its regulatory effect on epithelial‑mesenchymal transition in intrahepatic cholangiocarcinoma cells Open
Intrahepatic cholangiocarcinoma (ICC) is a highly invasive malignant tumor. The prognosis of patients with ICC after radical surgical resection remains poor, due to local infiltration, distant metastasis, a high recurrence rate and lack of…
View article: Liproxstatin-1 attenuates acute hypertriglyceridemic pancreatitis through inhibiting ferroptosis in rats
Liproxstatin-1 attenuates acute hypertriglyceridemic pancreatitis through inhibiting ferroptosis in rats Open
Ferroptosis is closely associated with inflammatory diseases, including acute pancreatitis (AP); however, the involvement of ferroptosis in hypertriglyceridemic pancreatitis (HTGP) remains unclear. In the present study, we aimed to explore…
View article: MZB1 regulates cellular proliferation, mitochondrial dysfunction, and inflammation and targets the PI3K-Akt signaling pathway in acute pancreatitis
MZB1 regulates cellular proliferation, mitochondrial dysfunction, and inflammation and targets the PI3K-Akt signaling pathway in acute pancreatitis Open
AP cells and tissues exhibited markedly elevated levels of MZB1 expression compared to their healthy counterparts. MZB1 overexpression promoted proliferation and supressed apoptosis, mitochondrial dysfunction, and inflammation in pancreati…
View article: Clinical practice guidelines for gene therapy to treat hereditary hearing loss
Clinical practice guidelines for gene therapy to treat hereditary hearing loss Open
Hereditary deafness is a common neurosensory disorder, and 148 non‐syndromic deafness genes have been identified to date. Gene therapy has been used to treat a variety of genetic diseases, but no gene therapy drug for hereditary deafness h…
View article: Author Correction: Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11
Author Correction: Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11 Open
View article: RETRACTED ARTICLE: Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer
RETRACTED ARTICLE: Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer Open
We, the Editors and Publisher of the Cell Cycle journal, have retracted the following article: Dingsheng Liu, Hong Zhang, Mingming Cui, Chunsheng Chen and Yong Feng. Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTN…
View article: Interaction of Dietary Fiber and Soluble To Insoluble Dietary Fiber Ratio in Improving Production Performance, Meat Quality and Muscle Fiber Type Transformation in Finishing Pigs
Interaction of Dietary Fiber and Soluble To Insoluble Dietary Fiber Ratio in Improving Production Performance, Meat Quality and Muscle Fiber Type Transformation in Finishing Pigs Open
View article: [Analysis of the feasibility and prognostic value of circulating tumor DNA monitoring in detecting gene mutations in patients with diffuse large B-cell lymphoma receiving chimeric antigen receptor T-cell therapy].
[Analysis of the feasibility and prognostic value of circulating tumor DNA monitoring in detecting gene mutations in patients with diffuse large B-cell lymphoma receiving chimeric antigen receptor T-cell therapy]. Open
Objective: To explore the prognostic value of circulating tumor DNA (ctDNA) testing in patients with refractory/relapsed diffuse large B-cell lymphoma (R/R DLBCL) undergoing chimeric antigen receptor T-cell (CAR-T) therapy, and to g…
View article: A Novel <i>EYA1</i> Mutation Causing Alternative RNA Splicing in a Chinese Family With Branchio-Oto Syndrome: Implications for Molecular Diagnosis and Clinical Application
A Novel <i>EYA1</i> Mutation Causing Alternative RNA Splicing in a Chinese Family With Branchio-Oto Syndrome: Implications for Molecular Diagnosis and Clinical Application Open
Objectives. Branchio-oto syndrome (BOS) primarily manifests as hearing loss, preauricular pits, and branchial defects. EYA1 is the most common pathogenic gene, and splicing mutations account for a substantial proportion of cases. Ho…
View article: Editorial: Etiological mechanisms and treatments of idiopathic sudden sensorineural hearing loss
Editorial: Etiological mechanisms and treatments of idiopathic sudden sensorineural hearing loss Open
EDITORIAL article Front. Neurol., 28 September 2023Sec. Neuro-Otology Volume 14 - 2023 | https://doi.org/10.3389/fneur.2023.1292836
View article: Gene regulation analysis of patient-derived iPSCs and its CRISPR-corrected control provides a new tool for studying perturbations of ELMOD3 c.512A>G mutation during the development of inherited hearing loss
Gene regulation analysis of patient-derived iPSCs and its CRISPR-corrected control provides a new tool for studying perturbations of ELMOD3 c.512A>G mutation during the development of inherited hearing loss Open
The ELMOD3 gene is implicated in causing autosomal recessive/dominant non-syndromic hearing loss in humans. However, the etiology has yet to be completely elucidated. In this study, we generated a patient-derived iPSC line carrying ELMOD3 …
View article: Identification of a Family with van der Hoeve's syndrome Harboring a Novel COL1A1 Mutation and Generation of Patient-Derived iPSC Lines and CRISPR/Cas9-Corrected Isogenic iPSCs
Identification of a Family with van der Hoeve's syndrome Harboring a Novel COL1A1 Mutation and Generation of Patient-Derived iPSC Lines and CRISPR/Cas9-Corrected Isogenic iPSCs Open
Van der Hoeve's syndrome, also known as osteogenesis imperfecta (OI), is a genetic connective tissue disorder characterized by fragile, fracture-prone bone and hearing loss. The disease is caused by a gene mutation in one of the two type I…
View article: Comparative phylogenomics and phylotranscriptomics provide insights into the genetic complexity of nitrogen-fixing root-nodule symbiosis
Comparative phylogenomics and phylotranscriptomics provide insights into the genetic complexity of nitrogen-fixing root-nodule symbiosis Open
View article: Comparative Phylogenomics and Phylotranscriptomics Provide Insights into the Genetic Complexity of Nitrogen Fixing Root Nodule Symbiosis
Comparative Phylogenomics and Phylotranscriptomics Provide Insights into the Genetic Complexity of Nitrogen Fixing Root Nodule Symbiosis Open
Plant root nodule symbiosis (RNS) with mutualistic nitrogen-fixing bacteria is restricted to a single clade of angiosperms, the Nitrogen-Fixing Nodulation Clade (NFNC), and is best understood in the legume family. It is widely accepted tha…
View article: Tropoelastin-Pretreated Exosomes from Adipose-Derived Stem Cells Improve the Synthesis of Cartilage Matrix and Alleviate Osteoarthritis
Tropoelastin-Pretreated Exosomes from Adipose-Derived Stem Cells Improve the Synthesis of Cartilage Matrix and Alleviate Osteoarthritis Open
Mesenchymal stem cells (MSCs) have recently been widely used to treat osteoarthritis (OA). Our prior research shows that tropoelastin (TE) increases MSC activity and protects knee cartilage from OA-related degradation. The underlying mecha…
View article: Research and application progress in deep learning in otology.
Research and application progress in deep learning in otology. Open
With the optimization of deep learning algorithms and the accumulation of medical big data, deep learning technology has been widely applied in research in various fields of otology in recent years. At present, research on deep learning in…
View article: Evolution of antimicrobial cysteine-rich peptides in plants
Evolution of antimicrobial cysteine-rich peptides in plants Open
To defend against diverse groups of pathogens, plants produce cysteine-rich peptides (CRPs) with long-lasting broad-spectrum antimicrobial activity. We analyzed 240 plant genomes ranging from algae to eudicots and our comparative genomics …
View article: Identification of short open reading frames in plant genomes
Identification of short open reading frames in plant genomes Open
The roles of short/small open reading frames (sORFs) have been increasingly recognized in recent years due to the rapidly growing number of sORFs identified in various organisms due to the development and application of the Ribo-Seq techni…