Yubing Wen
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View article: Global, regional, and national burden of diabetes mellitus due to metabolic factors in young adults, 1990 to 2021 and predictions to 2040: An analysis of the Global Burden of Disease Study 2021
Global, regional, and national burden of diabetes mellitus due to metabolic factors in young adults, 1990 to 2021 and predictions to 2040: An analysis of the Global Burden of Disease Study 2021 Open
Diabetes mellitus due to metabolic factors is a significant global public health burden, showing an increasing trend among young adults aged 24 to 49 years. This group, who are at the peak of their career development and family obligations…
View article: Classical complement activation in light and heavy chain deposition disease with acquired cutis laxa and bronchiolitis obliterans: a case report of monoclonal gammopathy of clinical significance
Classical complement activation in light and heavy chain deposition disease with acquired cutis laxa and bronchiolitis obliterans: a case report of monoclonal gammopathy of clinical significance Open
Light and heavy chain deposition disease (LHCDD) is a clonal plasma cell or monoclonal B-cell dyscrasia characterized by deposition of monoclonal immunoglobulin light and heavy chains. LHCDD mainly belongs to monoclonal gammopathy of renal…
View article: MIPV-NWP-PINN V1.0: Development of a Multi-scale Photovoltaic Power Forecasting Framework Integrating Numerical Weather Prediction with Physics-Informed Neural Networks
MIPV-NWP-PINN V1.0: Development of a Multi-scale Photovoltaic Power Forecasting Framework Integrating Numerical Weather Prediction with Physics-Informed Neural Networks Open
Photovoltaic (PV) power generation has become a cornerstone of clean energy, for which accurate forecasting is essential to ensure safe and efficient grid integration. However, raw Numerical Weather Prediction (NWP) outputs often fail to p…
View article: Spatial heterogeneity of dust size distribution on photovoltaic arrays: A wind tunnel experimental study
Spatial heterogeneity of dust size distribution on photovoltaic arrays: A wind tunnel experimental study Open
View article: #2058 Clinical manifestation and prognosis of membranous nephropathy in aged patients with primary Sjögren syndrome
#2058 Clinical manifestation and prognosis of membranous nephropathy in aged patients with primary Sjögren syndrome Open
Background and Aims Primary Sjögren syndrome (pSS) in aged patients complicated with glomerular disease was rare, with only a few reported cases. We tried to analyze the clinicopathological features and prognosis in elderly pSS patients co…
View article: #1987 Single-nucleus multi-omic profiling identified different extent of podocyte injury and podocyte-parietal epithelial cell communication in podocytopathy
#1987 Single-nucleus multi-omic profiling identified different extent of podocyte injury and podocyte-parietal epithelial cell communication in podocytopathy Open
Background and Aims The mechanism underlying podocyte disorder in primary focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD) remains unclear. This study aimed to identify the potential pathogenesis of podocytopathy …
View article: Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma
Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma Open
View article: Effectiveness of an intelligent weight-bearing rehabilitation robot in enhancing recovery following anterior cruciate ligament reconstruction
Effectiveness of an intelligent weight-bearing rehabilitation robot in enhancing recovery following anterior cruciate ligament reconstruction Open
Aim Orthopedic surgery patients frequently delay early rehabilitation due to postoperative discomfort. This is especially true for younger patients with anterior cruciate ligament injuries who are eager to return to sports after discharge.…
View article: Mediating effects of social detachment in young and middle-aged stroke patients between stigma and ability to return to work
Mediating effects of social detachment in young and middle-aged stroke patients between stigma and ability to return to work Open
Objective To investigate the mediating effect of social isolation on the relationship between stigma and work ability in young and middle-aged stroke patients. Methods From May 2022 to May 2024, a survey was conducted on young and middle-a…
View article: Dust deposition characteristics on photovoltaic arrays investigated through wind tunnel experiments
Dust deposition characteristics on photovoltaic arrays investigated through wind tunnel experiments Open
Optimizing the installation parameters of photovoltaic panels in a photovoltaic array to reduce dust accumulation, thereby enhancing their power generation, is a crucial research topic in the construction of solar power stations in desert …
View article: Grain Size Characteristics of Dust Deposition in Photovoltaic Arrays and its Effect on Glass Transmittance
Grain Size Characteristics of Dust Deposition in Photovoltaic Arrays and its Effect on Glass Transmittance Open
View article: Clinicopathological characteristics of patients with low titer anti-phospholipase A2 receptor antibodies verified by indirect immunofluorescence assay
Clinicopathological characteristics of patients with low titer anti-phospholipase A2 receptor antibodies verified by indirect immunofluorescence assay Open
Both pMN and non-pMN patients presented grey-zone PLA2R-ELISA results. It was necessary to perform PLA2R-IIF to assist in the diagnosis of patients with PLA2R-ELISA grey-zone results.
View article: Case report: Nephrotic syndrome and portal hypertensive ascites after allogeneic hematopoietic stem cell transplantation: a rare manifestation of chronic graft-versus-host disease
Case report: Nephrotic syndrome and portal hypertensive ascites after allogeneic hematopoietic stem cell transplantation: a rare manifestation of chronic graft-versus-host disease Open
Chronic graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem cell transplantation (HSCT). Chronic GVHD may have atypical manifestations affecting non-classical organs. The diagnosis in patients with …
View article: Application of a specialist nurse–led wireless smart monitoring system in elderly patients with persistent atrial fibrillation
Application of a specialist nurse–led wireless smart monitoring system in elderly patients with persistent atrial fibrillation Open
Background: With the increase in the elderly population, the prevalence of persistent atrial fibrillation (AF) among older adults has significantly risen, becoming one of the crucial cardiovascular diseases affecting the health and quality…
View article: #2699 Rare glomerular microangiopathy: clinicopathological characteristics and prognosis
#2699 Rare glomerular microangiopathy: clinicopathological characteristics and prognosis Open
Background and Aims Different from the typical histologic changes of thrombotic microangiopathy (TMA), we identified a group of patients whose pathology with glomerular involvement without blood vessel lesions, which was rare and known as …
View article: A case report of youth-onset lipoprotein glomerulopathy with APOE Chicago mutation
A case report of youth-onset lipoprotein glomerulopathy with APOE Chicago mutation Open
View article: Rare renal proximal tubular dysfunctions in primary biliary cholangitis
Rare renal proximal tubular dysfunctions in primary biliary cholangitis Open
Renal involvement of primary biliary cholangitis (PBC) usually presents as distal renal tubular acidosis. Proximal tubular (PT) dysfunctions in PBC were rarely reported with unclear clinicopathological characteristics and renal prognosis. …
View article: The Impact of Pv Array Tilt Angle and Installation Height on Wind Speed Profiles
The Impact of Pv Array Tilt Angle and Installation Height on Wind Speed Profiles Open
View article: [Therapeutic effect of mycophenolate mofetil or cyclophosphamide in children with Henoch-Schönlein purpura nephritis of different age groups].
[Therapeutic effect of mycophenolate mofetil or cyclophosphamide in children with Henoch-Schönlein purpura nephritis of different age groups]. Open
The efficacy and adverse reactions of MMF are not associated with age, but the efficacy of CTX is affected by age, with a higher incidence rate of adverse reactions. CTX should be selected with caution for children with HSPN aged >12 years.
View article: Development of a multiple convolutional neural network–facilitated diagnostic screening program for immunofluorescence images of IgA nephropathy and idiopathic membranous nephropathy
Development of a multiple convolutional neural network–facilitated diagnostic screening program for immunofluorescence images of IgA nephropathy and idiopathic membranous nephropathy Open
Background Immunoglobulin A nephropathy (IgAN) and idiopathic membranous nephropathy (IMN) are the most common glomerular diseases. Immunofluorescence (IF) tests of renal tissues are crucial for the diagnosis. We developed a multiple convo…
View article: #3424 RENAL OUTCOMES IN THE ELDERLY WITH ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODY-ASSOCIATED VASCULITIS: A NEW PREDICTION MODEL
#3424 RENAL OUTCOMES IN THE ELDERLY WITH ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODY-ASSOCIATED VASCULITIS: A NEW PREDICTION MODEL Open
Background and Aims Antineutrophil cytoplasmic autoantibody-associated vasculitis (AAV) is a type of necrotizing small vessel inflammatory disease, including alveolar hemorrhage and rapidly progressive glomerulonephritis. Elderly patients …
View article: #3412 THE THROMBOTIC EVENTS IN PATIENTS WITH ANCA-ASSOCIATED VASCULITIS: A RETROSPECTIVE COHORT STUDY AND MENDELIAN RANDOMIZATION ANALYSIS
#3412 THE THROMBOTIC EVENTS IN PATIENTS WITH ANCA-ASSOCIATED VASCULITIS: A RETROSPECTIVE COHORT STUDY AND MENDELIAN RANDOMIZATION ANALYSIS Open
Background and Aims Thrombotic event in ANCA-associated vasculitis (AAV) was prevalent but not clarified in the causal relationship between AAV and thrombotic events. We tried to identify the clinical characteristics and risk factors of th…
View article: #3420 CLINICAL CHARACTERISTICS AND PRIMARY OUTCOMES OF PATIENTS WITH ANCA-ASSOCIATED VASCULITIS AND CENTRAL DIABETES INSIPIDUS
#3420 CLINICAL CHARACTERISTICS AND PRIMARY OUTCOMES OF PATIENTS WITH ANCA-ASSOCIATED VASCULITIS AND CENTRAL DIABETES INSIPIDUS Open
Background and Aims Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is characterized by systemic small-vessel vasculitis and may rarely present as central diabetes insipidus (CDI). AAV-associated CDI should be recog…
View article: High Intake of Dietary Cholesterol Decreases the Risk of All-Cause Dementia and AD Dementia: A Results from Framingham Offspring Cohort
High Intake of Dietary Cholesterol Decreases the Risk of All-Cause Dementia and AD Dementia: A Results from Framingham Offspring Cohort Open
High intake of dietary cholesterol was associated with a decreased risk of all-cause dementia and AD dementia. The findings of this observational study need to be confirmed by other studies to highlight the role of dietary cholesterol in t…
View article: Clinical characteristics and primary outcomes of patients with ANCA-associated vasculitis and central diabetes insipidus
Clinical characteristics and primary outcomes of patients with ANCA-associated vasculitis and central diabetes insipidus Open
Introduction Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is characterized by systemic small-vessel vasculitis and may rarely present as central diabetes insipidus (CDI). In this study, we aimed to determine the …
View article: The Safety and Efficacy of Rituximab-Based Regimen in Atypical Membranous Nephropathy: A Single Center Retrospective Cohort Study
The Safety and Efficacy of Rituximab-Based Regimen in Atypical Membranous Nephropathy: A Single Center Retrospective Cohort Study Open
In our study, AMN patients obtained proteinuria remission in a lower percentage compared with IMN patients. In general, rituximab-based therapy is effective in AMN patients with an acceptable safety profile.
View article: Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury
Aldehyde dehydrogenase 2 alleviates mitochondrial dysfunction by promoting PGC-1α-mediated biogenesis in acute kidney injury Open
View article: Clinicopathological Features of Gitelman Syndrome with Proteinuria and Renal Dysfunction
Clinicopathological Features of Gitelman Syndrome with Proteinuria and Renal Dysfunction Open
Introduction: Gitelman syndrome (GS) is a rare renal tubular salt-wasting disorder. Besides kidney electrolyte loss, proteinuria and renal dysfunction were also observed. However, their incidence, risk factors, pathological features, and p…
View article: Interstitial nephritis without glomerulonephritis in ANCA-associated vasculitis: a case series and literature review
Interstitial nephritis without glomerulonephritis in ANCA-associated vasculitis: a case series and literature review Open
The typical nephrological presentation of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) is rapidly progressive glomerulonephritis. AAV-associated interstitial nephritis without apparent glomerular lesions was rare.…
View article: MO252: Complement 3 Deposits on Renal Tubule and Glomeruli in Phospholipase A2 Receptor-Related Idiopathic Membranous Nephropathy
MO252: Complement 3 Deposits on Renal Tubule and Glomeruli in Phospholipase A2 Receptor-Related Idiopathic Membranous Nephropathy Open
BACKGROUND AND AIMS Evidence shows galactose-deficient IgG4 is able to act complement system via lectin pathway in phospholipase A2 receptor (PLA2R) related idiopathic membranous nephropathy (IMN). However, the severity of PLA2R-related IM…