Explanipedia

Marine antifouling coating with dual antifouling mechanism based on medetomidine Open

Miao-Qing Sheng, Mingyang Zhang, Yongyin Cui, Yuan Feng, Zhizhou Zhang , et al. · 2025

Finite Element Modeling and Performance Evaluation of a Novel 3D Isolation Bearing Open

LI Jian-jun, Li Sun, Yan‐Chao Wu, Yun Chen, Dengzhou Quan , et al. · 2025

A numerical investigation is conducted to examine the mechanical properties of a novel three-dimensional (3D) isolation bearing. This device is primarily composed of a lead rubber bearing (LRB), disc springs, and U-shaped dampers. A finite…

The wzc mutation mediates virulence changes in K1-type Klebsiella pneumoniae within the same patient Open

Gaoqin Teng, Qiuying Qin, Shuo Ding, Yan‐Chao Wu, Yingying Fu , et al. · 2025

Hypervirulent Klebsiella pneumoniae (hvKp) is a major pathogen causing community-acquired infections, particularly severe diseases such as liver abscesses. Although extensive research has been conducted on the virulence mechanisms of hvKp …

tRNA selectivity during ribosome-associated quality control regulates the critical sterility-inducing temperature in two-line hybrid rice Open

Can Zhou, Chunyan Liu, Bin Yan, Jing Sun, Shengdong Li , et al. · 2025

The two-line hybrid rice system, a cutting-edge hybrid rice breeding technology, has greatly boosted global food security. In thermo-sensitive genic male sterile (TGMS) lines, the critical sterility-inducing temperature (CSIT; the temperat…

Eccentric Compression Behavior of RCFST Columns with Web Perforated T-Shaped Stiffeners Open

Qifan Jiang, Jun Zhang, Li Sun, Yan‐Chao Wu, Tuo Lei · 2025

Based on the previous axial compression tests by the authors, this study investigates the eccentric compression behavior of rectangular concrete-filled steel tubular (RCFST) columns with web-perforated T-shaped stiffeners through finite el…

Application of a novel extracorporeal membrane oxygenation system in awake Hu sheep under various durations Open

Shuo Ding, Juan Chen, Yan‐Chao Wu, Hung-Mo Lin, Qiqiang Liang , et al. · 2025

In healthy Hu sheep models with different maintenance periods, the novel ECMO support in awake state demonstrated high safety and feasibility.

A phytoalexin-inspired, natural product-based marine antifouling coating with synergistic active antimicrobial and passive anti-adhesive performances Open

Liang Ma, X. Lei, Qi Xu, Yan Li, Pengfei Chen , et al. · 2025

Multi-Strategy Synergetic Coating Based on Natural Product Resveratrol for Marine Antifouling Open

Liang Ma, Yan‐Chao Wu, X. Lei, Qi Xu, Yuhao Li , et al. · 2025

Surface immobilization of single atoms on heteroatom-doped carbon nanospheres through phenolic-mediated interfacial anchoring for highly efficient biocatalysis Open

Yajing Zhang, Yunxiang He, Yun Jiao, Guobin Yang, Yiran Pu , et al. · 2025

Single-atom catalysts (SACs) via phenolic-mediated interfacial anchoring (PIA) with single Fe atoms dispersed on the surface of N/P-doped carbon supports, exhibiting exceptional biocatalytic properties.

Comprehensive Analysis of Degradation of Fucosylated Chondroitin Sulfate by Human Gut Microbiota in Vitro Open

Pi‐Xian Gong, Chao Dong, Siqi Lu, Xin Xie, Jinyan Dong , et al. · 2025

Application of polymer corrosion inhibitors in metal corrosion control: a review Open

Y M Liu, Feiyu Chen, Baozheng Wang, Hongyan Ma, Yuanyuan Wang , et al. · 2024

Corrosion can bring serious safety issues, environmental issues, and economic losses. The use of corrosion inhibitors is an important technology for controlling metal corrosion. Compared to small molecule corrosion inhibitors, polymer corr…

Chemical constituents from <i>Uncaria laevigata</i> and their anti-inflammatory activities and action mechanism Open

Li Huang, Ziming Wang, Qing Zhao, Hui‐Jing Li, Yan‐Chao Wu · 2024

A new alkaloid 1* (scandine Z) and fourteen known natural products were isolated from 95% ethanol extract of Uncaria laevigata for the first time. Besides compound 1*, these fourteen compounds were firstly isolated fro…

Co-Encapsulation of Curcumin and Diosmetin in Nanoparticles Formed by Plant-Food-Protein Interaction Using a pH-Driven Method Open

Chong Yu, Jingyu Shan, Ze Fu, Hao Ju, Xiao Chen , et al. · 2023

In this work, a pH-driven method was used to prepare zein–soy protein isolate (SPI) composite nanoparticles (NPs). The mass ratio of SPI to zein influenced the Z-average size (Z-ave). Once the zeta potential stabilized, SPI was completely …

Recent trends in anti-cancer activities of terrestrial plants-based polysaccharides: A review Open

Hao Ju, Chong Yu, Xian-Dong Zhang, Wei Liu, Yan‐Chao Wu , et al. · 2023

Cancer has become one of the major diseases threatening human health. Conventional therapies have great adverse effects and are prone to drug resistance, and novel therapies are expensive and cause a heavy burden to patients. Plant polysac…

Polysaccharides from marine resources exhibit great potential in the treatment of tumor: A review Open

Hao Ju, Chong Yu, Wei Liu, Hai-Huang Li, Ze Fu , et al. · 2023

Tumor refers to the neogrowth formed by the hyperplasia of local tissue cells under various tumor factors. Because this new creature mostly appears in a lump -like protrusions, also known as neoplasm. Relevant investigation shows that mill…

Dearomatization of Halonaphthols via an Intermolecular [4＋1] Spiroannulation with in situ Formed Aza-ortho-quinone Methides Open

Junxiu Liang, Yazhou Liu, Amu Wang, Yan‐Chao Wu, Xiaofeng Ma , et al. · 2023

A base promoted dearomatization strategy for [4＋1] spiroannulation of halonaphthols with N-(o-chloromethyl) aryl amides is reported, which is used to efficiently synthesize azaspirocycles.A range of azaspirocycles were obtained in satisfac…

Comparison of Health-Relevant Polyphenolic Component Content and Bioavailability of Bilberry (Vaccinium Myrtillus L.), Blueberry (Vaccinium Sect. Cyanococcus Rydb.) and Chokeberry (Aronia Melanocarpa (Michx.) Elliott) Open

Xiao Chen, Yan‐Chao Wu, Liu-Hong Qian, Yuhe Zhang, Pi‐Xian Gong , et al. · 2022

The fruit-based dietary supplement business is flourishing, and many plant bioactive compounds exhibit beneficial effects on health. Polyphenols, including anthocyanins, proanthocyanidins, flavanols, phenolic acids and flavanols in bilberr…

Ceftazidime/Avibactam versus Polymyxin B in the Challenge of Carbapenem-Resistant Pseudomonas aeruginosa Infection Open

Juan Chen, Qiqiang Liang, Xinyi Chen, Jing Wu, Yan‐Chao Wu , et al. · 2022

Juan Chen,* Qiqiang Liang,* Xinyi Chen, Jing Wu, Yanchao Wu, Gaoqin Teng, Man Huang Department of General Intensive Care Unit, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic …

Stress analysis of the thoracolumbar junction in the process of backward fall: An experimental study and finite element analysis Open

Peidong Sun, Xiaoxiang Zhang, Yuan‐Wei Zhang, Zhe Wang, Xiaoyu Wu , et al. · 2021

The aim of the present study was to evaluate the biomechanical mechanism of injuries of the thoracolumbar junction by the methods of a backward fall simulation experiment and finite element (FE) analysis (FEA). In the backward fall simulat…

Application of marine natural products in drug research Open

Wen‐Yu Lu, Huijing Li, Qinying Li, Yan‐Chao Wu · 2021

Design, synthesis and biological evaluation of novel N-sulfonylamidine-based derivatives as c-Met inhibitors via Cu-catalyzed three-component reaction Open

Xiang Nan, Jing Zhang, Hui‐Jing Li, Rui Wu, Senbiao Fang , et al. · 2020

Structure-based discovery of novel 4-(2-fluorophenoxy)quinoline derivatives as c-Met inhibitors using isocyanide-involved multicomponent reactions Open

Xiang Nan, Hui‐Jing Li, Senbiao Fang, Qinying Li, Yan‐Chao Wu · 2020

CCDC 1939330: Experimental Crystal Structure Determination Open

Yuan-Zhao Ji, Hui‐Jing Li, Ying Liu, Yan‐Chao Wu · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1939331: Experimental Crystal Structure Determination Open

Yuan-Zhao Ji, Hui‐Jing Li, Ying Liu, Yan‐Chao Wu · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Approaches to the Total Synthesis of Puupehenone-Type Marine Natural Products Open

Yan‐Chao Wu, Yunfei Cheng, Hui‐Jing Li · 2019

Puupehenones have been isolated from the marine sponge Chondrosia chucalla, which belong to a growing family of natural products with more than 100 members. These marine natural products have attracted increasing attention mainly due to th…

Design, synthesis and evaluation of sulfonylurea-containing 4-phenoxyquinolines as highly selective c-Met kinase inhibitors Open

Xiang Nan, Yifan Jiang, Hui‐Jing Li, Junhu Wang, Yan‐Chao Wu · 2019

Regioselective synthesis of gentisyl alcohol-type marine natural products Open

Hongshuang Wang, Hui‐Jing Li, Longfei Wang, Zhi‐Lun Shen, Yan‐Chao Wu · 2018

Gentisyl alcohol-type natural products, possessing various important biological properties, have been synthesized from 4-methoxyphenol by using a selective phenol monohydroxymethylation/monochlorination, a CAN oxidation and a sodium dithio…

SN38-loaded <100 nm targeted liposomes for improving poor solubility and minimizing burst release and toxicity: in vitro and in vivo study Open

Fang YP, Chuang CH, Yan‐Chao Wu, Lin HC, Lü Yc · 2018

Yi-Ping Fang,1,2 Chih-Hung Chuang,3 Yi-Jhun Wu,1 Hsin-Che Lin,1 Yun-Chi Lu4 1School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, 2Department of Medical Research, Kaohsiung Medical University Hospital, 3Department of Medi…

Similarity Retrieval Algorithm based on Multilevel Fingerprint Comparison Matrix Open

Qiang Lv, Feihu Duan, Yan‐Chao Wu, Jiaxing He · 2018

In order to carry out similarity retrieval in mass information accurately and efficiently, this paper proposes a similarity retrieval algorithm based on multilevel fingerprint comparison matrix.For mass text information, firstly, using the…

Pd-catalyzed aerobic oxidative annulation of cyclohexanones and 2-aminophenyl ketones: A direct approach to acridines Open

Wanlu Mu, Xiaowei Li, Longfei Wang, Yong Chen, Yan‐Chao Wu · 2017

An efficient aerobic oxidative annulation of cyclohexanones and 2-aminophenyl ketones approach to substituted acridines, a structural motif for a large number of pharmaceuticals and functional materials is described. The key feature of thi…

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