Yazdan Ghandi
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View article: Imbalance of Fetal Growth Factor Levels in Congenital Heart Disease Pathology: A Systematic Review
Imbalance of Fetal Growth Factor Levels in Congenital Heart Disease Pathology: A Systematic Review Open
Background Vascular endothelial growth factor (VEGF) is a factor that is responsible for cell proliferation, growth of vascular endothelial cells, and angiogenesis. Changes in the level of this factor are associated with the pathology of s…
View article: Investigation of Platelet-Related Parameters and BMI in Children with Cyanotic and Non-Cyanotic Congenital Heart Disease
Investigation of Platelet-Related Parameters and BMI in Children with Cyanotic and Non-Cyanotic Congenital Heart Disease Open
Background: Considering the role platelets play in hemostasis and coagulation, in the present study, we have examined plateletrelated parameters and BMI in children with cyanotic and non-cyanotic CHD. Methods: Fifty children with cyanotic …
View article: Sleep disorders lead to gray matter alterations children: a systematic review of cortical and subcortical points
Sleep disorders lead to gray matter alterations children: a systematic review of cortical and subcortical points Open
Background Morphological changes in the brain cortex can disrupt central nervous system activity, often resulting from neuroinflammation, neurodegenerative diseases, and sleep disorders. Sleep disorders are linked to alterations in the thi…
View article: Gray matter alterations in sleep disorders lead to brain networks changes: A systematic review of cortical and subcortical points
Gray matter alterations in sleep disorders lead to brain networks changes: A systematic review of cortical and subcortical points Open
Background Disorders are a common issue among children of various ages, often linked to alterations in the thickness and volume of the cortex in adults. However, the effects on cortical thickness and gray matter volume can differ in childr…
View article: Platelet Indices in Pediatric Patients with Congenital Heart Disease with and without Pulmonary Arterial Hypertension
Platelet Indices in Pediatric Patients with Congenital Heart Disease with and without Pulmonary Arterial Hypertension Open
Background: Pulmonary arterial hypertension (PAH) is an uncommon syndrome characterized by dyspnea and fatigue resulting from a progressive elevation in pulmonary vascular resistance. Recent research suggests that the relationship between …
View article: Imbalance of fetal growth factor levels in congenital heart disease pathology: a systematic review to investigate therapeutic potential
Imbalance of fetal growth factor levels in congenital heart disease pathology: a systematic review to investigate therapeutic potential Open
Background Vascular endothelial growth factor (VEGF) is a factor that is responsible for cell proliferation, vascular endothelial cell growth, and angiogenesis. Changes in the level of this factor are associated with the pathology of struc…
View article: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome and Myocarditis: A Case Report and Literature Review on Fatal Complications of Reactivated Viral Infections
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome and Myocarditis: A Case Report and Literature Review on Fatal Complications of Reactivated Viral Infections Open
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a complex and potentially fatal hypersensitivity condition. We present a unique case report and literature review focusing on DRESS syndrome-associated myocarditis resulting …
View article: Evaluation of the Relationship Between T2*CMR and Cardiac Depolarization and Repolarization Parameters in Beta-Thalassemia Patients
Evaluation of the Relationship Between T2*CMR and Cardiac Depolarization and Repolarization Parameters in Beta-Thalassemia Patients Open
Background: Cardiac iron overload causes severe cardiac complications and is a leading cause of death in beta-thalassemia major (B-TM) patients. T2-weighted cardiovascular magnetic resonance (T2*CMR) can detect preclinical cardiac iron ove…
View article: Correlation of Magnesium Level with Cardiac and Hepatic Hemosiderosis Measured by T2*MRI Technique and Age in Patients with Thalassemia Major
Correlation of Magnesium Level with Cardiac and Hepatic Hemosiderosis Measured by T2*MRI Technique and Age in Patients with Thalassemia Major Open
Background: Given the association of hypomagnesemia with cardiac arrhythmia, the aim of this study was to investigate the relationship between serum magnesium levels with age and T2* magnetic resonance imaging (MRI) findings of the heart a…
View article: Thyroid Function in Children with Cyanotic and Non-Cyanotic Congenital Heart Disease
Thyroid Function in Children with Cyanotic and Non-Cyanotic Congenital Heart Disease Open
Based on the present findings, subclinical hypothyroidism is a common finding in cyanotic CHD patients during childhood, which is associated with increased levels of oxygen saturation, severity of cyanosis, and age.
View article: Evaluation of Early Repolarization Pattern in Children with Mitral Valve Prolapse.
Evaluation of Early Repolarization Pattern in Children with Mitral Valve Prolapse. Open
The prevalence of ERP in children with MVP has been at a higher-level incidence, especially among patients with complaining from chest pain. We suggested that children with MVP are in need of follow up considering the occurrence of arrhyth…
View article: Effects of Mitral Valve Prolapse on Heart Rate Variability and the Autonomic Nervous System in Children
Effects of Mitral Valve Prolapse on Heart Rate Variability and the Autonomic Nervous System in Children Open
Background: Patients with mitral valve prolapse (MVP) may reveal symptoms of autonomic dysfunction and heart rate variability (HRV). We sought to explore the autonomic nervous system in children with MVP. Methods: This cross-sectional stud…
View article: Comparison of the Efficacy and Complications of Oral versus Intravenous Ibuprofen in Low-birth-weight Neonates with Patent Ductus Arteriosus: A Retrospective Cohort Study
Comparison of the Efficacy and Complications of Oral versus Intravenous Ibuprofen in Low-birth-weight Neonates with Patent Ductus Arteriosus: A Retrospective Cohort Study Open
Background: Patent ductus arteriosus (PDA) is associated with morbidity in preterm neonates. This study aimed to compare the efficacy of oral versus intravenous Ibuprofen in preterm neonates with PDA. Methods: 80 low birth weight neonates …
View article: A Rare Manifestation of Kawasaki Disease: Bloody Diarrhea Association with Acute Clinical Myocarditis
A Rare Manifestation of Kawasaki Disease: Bloody Diarrhea Association with Acute Clinical Myocarditis Open
Kawasaki disease (KD) is a systemic vasculitis of small and medium-sized vessels that mainly influences children under five. In the classic diagnostic criteria of KD, there is no Gastrointestinal involvement. Myocarditis is one of the unus…
View article: Congenital Scoliosis and Tetralogy of Fallot With Neurodevelopment Delay: A Case Study and Literature Review
Congenital Scoliosis and Tetralogy of Fallot With Neurodevelopment Delay: A Case Study and Literature Review Open
As the most common congenital heart malformation, tetralogy of Fallot (TOF) produces cyanosis. Patients with TOF suffer from a higher frequency of major noncardiac congenital disorders. Its association with congenital scoliosis influences …
View article: Evaluation of the Association between Blood Pressure and Birth Weight: A Cross-Sectional Study on 600 Outpatient Children
Evaluation of the Association between Blood Pressure and Birth Weight: A Cross-Sectional Study on 600 Outpatient Children Open
BackgroundDespite the declining global prevalence of preterm birth, it accounts for a certain proportion of births in developing countries. Those born earlier, are prone to have lower birth weight (BW), smaller kidneys, lower glomerular fi…
View article: Electrocardiography Adverse Effects Systemic Glucantime in a Child With Cutaneous Leishmaniosis: A Case Report and Brief Review
Electrocardiography Adverse Effects Systemic Glucantime in a Child With Cutaneous Leishmaniosis: A Case Report and Brief Review Open
Background: Antimonial compounds are the most common choice for the treatment of cutaneous Leishmaniosis (CL). Antimonial toxicities are common and cardiac toxicity is one of them, which leads to the electrocardiogram (ECG) changes. In thi…
View article: Association between the severity of chest pain and the severity of mitral valve prolapse in children
Association between the severity of chest pain and the severity of mitral valve prolapse in children Open
Introduction: One of the causes of chest pain in children is mitral valve prolapse (MVP). This study aimed to investigate the association between the severity of chest pain and the severity of MVP.\nMaterials and Methods: This cross-sectio…
View article: Evaluation of Blood Pressure in Pediatric Survivors of Acute Lymphoblastic Leukemia and Healthy Children; A Case-control Study
Evaluation of Blood Pressure in Pediatric Survivors of Acute Lymphoblastic Leukemia and Healthy Children; A Case-control Study Open
Background: The exact prevalence of hypertension in children surviving acute lymphoblastic leukemia (ALL) has not been fully estimated. The aim of this study was to investigate the prevalence of arterial hypertension (AH) and to determine …
View article: Evaluation the Effectiveness of Ibuprofen in Improving Patent Ductus Arteriosus
Evaluation the Effectiveness of Ibuprofen in Improving Patent Ductus Arteriosus Open
Background and Aim: Patent Ductus Arteriosus (PDA) is a common problem in premature neonates, especially in neonate’s low birth weight (LBW). This study aimed to compare the effectiveness of oral and intravenous ibuprofen in the management…
View article: Assessment of Correlation Between Costochondritis and Vitamin D Insufficiency in School-age Children
Assessment of Correlation Between Costochondritis and Vitamin D Insufficiency in School-age Children Open
Background: In children, vitamin D deficiency can result in the hypertrophy of costochondral junctions and sternal pain. Objectives: In this study, we aimed at determining the correlation between children’s vitamin D status and costochondri…
View article: Potts Shunt in Children With Familial Primary Pulmonary Hypertension: A Case Report and Brief Literature Review
Potts Shunt in Children With Familial Primary Pulmonary Hypertension: A Case Report and Brief Literature Review Open
Introduction: The primary concern about Familial Pulmonary Arterial Hypertension (FPAH) is the development of right heart failure, which ultimately leads to sudden death. Despite recent advances in pharmacological therapy, the mortality ra…
View article: Correlation between QRS Complex Changes and Cardiac Iron Overload in Beta Thalassemia Major Patients Using T2*MRI
Correlation between QRS Complex Changes and Cardiac Iron Overload in Beta Thalassemia Major Patients Using T2*MRI Open
Background and purpose: Cardiac magnetic resonance imaging (MRI) is a costly method to assess cardiac iron overload. The presence of fragmented QRS (fQRS) indicates changes due to iron overload in cardiac tissue. The aim of this study was …
View article: Evaluation of the Relationship Among Pulmonary Artery Pressure with Serum Ferritin Level and CMR T2* in Thalassemia Major.
Evaluation of the Relationship Among Pulmonary Artery Pressure with Serum Ferritin Level and CMR T2* in Thalassemia Major. Open
The PAP was positively correlated with serum ferritin levels and negatively with T2MRI. The accuracy of 80% for T2MRI as a method to diagnose or even anticipate PH among patients with TM suggested that this method is a useful and accurate …
View article: Dopamine and Drip Lasix in Pediatrics with Oliguria: A Clinical Trial Study
Dopamine and Drip Lasix in Pediatrics with Oliguria: A Clinical Trial Study Open
Background: Urine volume less than 1 mL/kg/h is called oliguria. The treatment of these patients is very important. Objectives: This study aimed to compare efficacy of dopamine and drip Lasix in children with oliguria. Methods: This study …
View article: Evaluation of Cardiac Troponin Level Following Generalized Tonic-Clonic Seizure in Children; Cross-sectional Study
Evaluation of Cardiac Troponin Level Following Generalized Tonic-Clonic Seizure in Children; Cross-sectional Study Open
Background: Cardiac troponin I (CTnI) is recognized as a proper marker for early detection of cardiac damage. Generalized tonic-clonic (GTC) seizures may lead to cardiac ischemia or myocardial injury associated with elevated CTnI. The pres…
View article: COVID-19 infection in children: A systematic review and meta-analysis of clinical features and laboratory findings
COVID-19 infection in children: A systematic review and meta-analysis of clinical features and laboratory findings Open
View article: Myocarditis, a Life-Threatening Presentation of COVID-19 in a 4-Month-Old Infant
Myocarditis, a Life-Threatening Presentation of COVID-19 in a 4-Month-Old Infant Open
Background and Aim: Significant cardiac sequelae may be one of the main causes of death in COVID-19 patients; however, very few reports are available that address these complications and their treatment strategies in children. Case Present…
View article: Evaluation of the Relationship Among Pulmonary Artery Pressure with Serum Ferritin Level and CMR T2* in Thalassemia Major
Evaluation of the Relationship Among Pulmonary Artery Pressure with Serum Ferritin Level and CMR T2* in Thalassemia Major Open
Background: Pulmonary hypertension is one of the most common cardiac complications among patients with β-thalassemia major (β-TM). The aim of this study is to investigate the correlation of pulmonary artery pressure (PAP), serum ferritin l…
View article: Effect of Sodium Valproate on Cardiac Function in Epileptic Children by Tissue Doppler Echocardiography
Effect of Sodium Valproate on Cardiac Function in Epileptic Children by Tissue Doppler Echocardiography Open
The antiepileptic Valproic acid (VPA) changes the oxidative/ anti-oxidative balance that results in oxidative stress and maybe an increased risk of cardiac dysfunction. The aim of this study was to investigate the effect of VPA on ventricu…