Yazun Jarrar
YOU?
Author Swipe
View article: Ocular adverse events associated with eye makeup: a cosmetovigilance-based cross-sectional study of prevalence and predictors among Jordanian women
Ocular adverse events associated with eye makeup: a cosmetovigilance-based cross-sectional study of prevalence and predictors among Jordanian women Open
This study aimed to investigate eye makeup adverse reactions (ARs), habits and practices among Jordanian females. The research also sought to identify factors contributing to the risk of ARs to promote safer cosmetic practices and protect …
View article: Simvastatin inhibits 20-Hydroxyeicosatetraenoic acid formation: docking and in vitro assay
Simvastatin inhibits 20-Hydroxyeicosatetraenoic acid formation: docking and in vitro assay Open
View article: Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers
Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers Open
This study concludes the presence of UGT1A5 and 2B15 mRNA in human platelets and their elevated level in the platelets of smokers. Further research, including pharmacokinetic studies and protein-level validation, is needed to understand th…
View article: Assessment of knowledge and perceptions of pharmacy students toward pharmacovigilance activities, and their predictors: a cross-sectional study in Palestine
Assessment of knowledge and perceptions of pharmacy students toward pharmacovigilance activities, and their predictors: a cross-sectional study in Palestine Open
View article: Unveiling etiology and mortality risks in community-acquired pneumonia: A machine learning approach
Unveiling etiology and mortality risks in community-acquired pneumonia: A machine learning approach Open
Community-acquired pneumonia (CAP) is associated with high mortality, and accurate diagnosis and risk prediction are essential for improving patient outcomes. Traditional diagnostic methods have limitations, prompting the use of machine le…
View article: Association of Vitamin D Serum Levels With Glycemic, Lipid Profiles, and Diabetic Complications in Saudi Type II Diabetes Patients
Association of Vitamin D Serum Levels With Glycemic, Lipid Profiles, and Diabetic Complications in Saudi Type II Diabetes Patients Open
View article: Novel Association of Thrombophilic PROS1, PROC and CPB2 Genes Polymorphisms with Recurrent Spontaneous Miscarriage Women in Jordan
Novel Association of Thrombophilic PROS1, PROC and CPB2 Genes Polymorphisms with Recurrent Spontaneous Miscarriage Women in Jordan Open
Recurrent spontaneous miscarriage (RSM) is a gynecological complication has multifactorial etiologies including genetic factors. However, role of thrombophilic gene polymorphisms in RSA among Jordanian women is limited. This study explores…
View article: Variability in Response to Valsartan and Its Relationship With <i>AGT M235T</i> Genotype and Other Nongenetic Parameters Among a Sample of Hypertensive Individuals in Jordan: A Prospective Pilot Study
Variability in Response to Valsartan and Its Relationship With <i>AGT M235T</i> Genotype and Other Nongenetic Parameters Among a Sample of Hypertensive Individuals in Jordan: A Prospective Pilot Study Open
Background Valsartan, an angiotensin receptor antagonist widely used in hypertension and heart failure management, exhibits noticeable interindividual variation in response among hypertensive patients at the University of Jordan Hospital. …
View article: Genetic Polymorphisms in Cytochrome P450 Enzymes Involved in Vitamin D Metabolism and the Vitamin D Receptor: Their Clinical Relevance
Genetic Polymorphisms in Cytochrome P450 Enzymes Involved in Vitamin D Metabolism and the Vitamin D Receptor: Their Clinical Relevance Open
Individual variations in the active form of vitamin D (Vit.D) arise from a combination of dietary intake, sun exposure, and genetic factors, making it complex and challenging to maintain optimal levels. Among Vit.D-related genes, variation…
View article: Genetic variants in <i>QRICH2</i> gene among Jordanians with sperm motility disorders
Genetic variants in <i>QRICH2</i> gene among Jordanians with sperm motility disorders Open
Sperm motility, a key determinant of male fertility, is often impaired by genetic variations affecting flagellar formation. The glutamine-rich protein 2 (QRICH2) gene encodes a protein essential for sperm flagella biogenesis …
View article: Recurrent Early Pregnancy Loss and Congenital Thrombophilia: A Prospective Study
Recurrent Early Pregnancy Loss and Congenital Thrombophilia: A Prospective Study Open
Background/Objectives: This study aims to investigate the role of congenital single nucleotide thrombophilia in young females with early recurrent pregnancy loss (RPL). Methods: We studied 120 pregnant females with RPL and 80 matched femal…
View article: Factors Associated with Tobacco Smoking Initiation in Jordan: A Cross-Sectional Study
Factors Associated with Tobacco Smoking Initiation in Jordan: A Cross-Sectional Study Open
we can conclude that older age groups tended to start smoking slightly later on average than younger groups. Overall, females began smoking at a significantly later age of 19.6 years than males at 16.8 years.
View article: Nephro- and Cardiotoxic Effects of Etoricoxib: Insights into Arachidonic Acid Metabolism and Beta-Adrenergic Receptor Expression in Experimental Mice
Nephro- and Cardiotoxic Effects of Etoricoxib: Insights into Arachidonic Acid Metabolism and Beta-Adrenergic Receptor Expression in Experimental Mice Open
Background: Etoricoxib is a widely used anti-inflammatory drug, but its safety profile concerning cardiovascular and renal health remains inadequately explored. This study aimed to assess the nephro- and cardiotoxic effects of etoricoxib i…
View article: Assessment the Combining Medications with Tobacco during Water-Pipe Smoking among the University Students in Jordan
Assessment the Combining Medications with Tobacco during Water-Pipe Smoking among the University Students in Jordan Open
This study provides valuable insights into the complex phenomenon of drug mixing with tobacco in water-pipe smoking among university students in Jordan. The findings highlight the need for further research on clinical implications and inte…
View article: The Association of M235T Genetic Polymorphism in Angiotensinogen Gene and Other Non-Genetic Factors with Essential Hypertension among Jordanian Patients
The Association of M235T Genetic Polymorphism in Angiotensinogen Gene and Other Non-Genetic Factors with Essential Hypertension among Jordanian Patients Open
Background: Hypertension, characterized by elevated pressure, poses a significant health risk. Recent studies in Jordan highlight high hypertension rates, emphasizing the need for genetic investigations to comprehend essential hypertension…
View article: Nanoencapsulated Curcumin Mitigates Liver Injury and Drug-Metabolizing Enzymes Induction in Diclofenac-Treated Mice
Nanoencapsulated Curcumin Mitigates Liver Injury and Drug-Metabolizing Enzymes Induction in Diclofenac-Treated Mice Open
Curcumin (CUR) is a natural product with known anti-inflammatory, antioxidant, and hepatoprotective properties. The aim of this study was to formulate CUR into a polymeric nanoparticle (NP) formulation and examine its potential hepatoprote…
View article: Phytochemical Investigation and Biological Activities of <i>Ruta chalepensis</i> Methanolic Extract: Antioxidant, Anti‐Inflammatory, Anticollagenase, and Antielastase Properties
Phytochemical Investigation and Biological Activities of <i>Ruta chalepensis</i> Methanolic Extract: Antioxidant, Anti‐Inflammatory, Anticollagenase, and Antielastase Properties Open
Ruta chalepensis has long been recognized in traditional medicine for its diverse pharmacological properties. The primary aim of this study was to analyze the phytochemical composition and evaluate the antioxidant, anti‐inflammatory, antic…
View article: Medicine and Pharmacy Students’ Knowledge, Attitudes, and Practice regarding Artificial Intelligence Programs: Jordan and West Bank of Palestine
Medicine and Pharmacy Students’ Knowledge, Attitudes, and Practice regarding Artificial Intelligence Programs: Jordan and West Bank of Palestine Open
While most medicine and pharmacy students had heard about AI programs, only a small proportion of the participants had used them in their medical study. In addition, attitudes and practice related to AI programs in their education differs …
View article: Exploring the Influence of VDR Genetic Variants TaqI, ApaI, and FokI on COVID-19 Severity and Long-COVID-19 Symptoms
Exploring the Influence of VDR Genetic Variants TaqI, ApaI, and FokI on COVID-19 Severity and Long-COVID-19 Symptoms Open
There is increasing evidence regarding the importance of vitamin D in the prognosis of coronavirus disease 2019 (COVID-19). Genetic variants in the vitamin D receptor (VDR) gene affect the response to vitamin D and have been linked to vari…
View article: Assessment of Perceptions and Predictors Towards Consanguinity: A Cross-Sectional Study from Palestine
Assessment of Perceptions and Predictors Towards Consanguinity: A Cross-Sectional Study from Palestine Open
Consanguinity prevalence has decreased among recent generations in Palestine, but it remains a significant challenge in Palestine. Therefore, educational and awareness programs about consanguinity and its health effects are effective strat…
View article: Effects of intermittent fasting on the histology and mRNA expression of major drug-metabolizing cyp450s in the liver of diabetic mice
Effects of intermittent fasting on the histology and mRNA expression of major drug-metabolizing cyp450s in the liver of diabetic mice Open
Introduction:There is a variation in drug response among patients who practice intermittent fasting. Alteration in the expression of drug-metabolizing enzymes (DMEs) can affect the pharmacokinetics and drug response.Aims: This research aim…
View article: Does Ramadan Intermittent Fasting Affect the Fasting Blood Glucose Level among Type II Diabetic Patients?
Does Ramadan Intermittent Fasting Affect the Fasting Blood Glucose Level among Type II Diabetic Patients? Open
Background: The level of fasting blood glucose (FBG) is influenced by several factors, including health status, genetics, and diet. Some studies have reported a beneficial effect of Ramadan Intermittent Fasting (RIF) on diabetic patients. …
View article: Clinical Significance of NAT2 Genetic Variations in Type II Diabetes Mellitus and Lipid Regulation
Clinical Significance of NAT2 Genetic Variations in Type II Diabetes Mellitus and Lipid Regulation Open
The finding in this study suggests that the NAT2 gene is a potential biomarker for the development of T2DM and changes in triglyceride levels among Jordanians. However, it is important to note that our sample size was limited; there…
View article: Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice
Flumazenil Pretreatment Reduces Mefenamic Acid-Induced Central Nervous System Toxicity in Mice Open
Background: Mefenamic acid (MFA), a common analgesic, causes central nervous system (CNS) toxicity at high doses with a proposed activity on the Gamma-aminobutyric acid (GABA) system. However, it remains unknown whether flumazenil (FMZ), a…
View article: Effects of Sex and Androgenic Drugs on the Expression of Angiotensin-Converting Enzyme 2 Receptor, Cathepsin l and Transmembrane Serine Protease in Mouse Lungs
Effects of Sex and Androgenic Drugs on the Expression of Angiotensin-Converting Enzyme 2 Receptor, Cathepsin l and Transmembrane Serine Protease in Mouse Lungs Open
Introduction: Although males and females have the same prevalence of COVID-19, a variation in the severity of symptoms between males and females has been observed. We hypothesize that this variation can partly be explained by the effect of…
View article: The Prevalence and Risk Factors of COVID-Stress Syndrome
The Prevalence and Risk Factors of COVID-Stress Syndrome Open
Background COVID-19 is a serious disease causing negative psychological effects such as nervousness, isolation, depression, and suicide ideation. The COVID Stress Scale was developed to better understand and assess COVID-19-related distres…
View article: Modulation of IRAK enzymes as a therapeutic strategy against SARS-CoV-2 induced cytokine storm
Modulation of IRAK enzymes as a therapeutic strategy against SARS-CoV-2 induced cytokine storm Open
View article: Anxiolytic Effect of Ethanolic Extract of Medjool Dates of Phoenix Dactylifera in Mice
Anxiolytic Effect of Ethanolic Extract of Medjool Dates of Phoenix Dactylifera in Mice Open
Background: Anxiety is one of the most frequent psychiatric disorders, affecting 33.7% of the general population. However, the consumption of healthy diets has been found to help, at least in part, in the prevention and treatment of anxiet…
View article: Alteration of the Respiratory Microbiome in Hospitalized Patients with Asthma–COPD Overlap during and after an Exacerbation
Alteration of the Respiratory Microbiome in Hospitalized Patients with Asthma–COPD Overlap during and after an Exacerbation Open
The immediate aim of this study was to comparatively examine the bacterial respiratory microbiome of patients in a stable state and during an exacerbation of asthma–COPD (chronic obstructive pulmonary disease) overlap (ACO). This prospecti…
View article: Knowledge and Awareness toward Viral Diseases among University Students in Jordan: Spring 2020
Knowledge and Awareness toward Viral Diseases among University Students in Jordan: Spring 2020 Open
Background: Little is known about the viral disease knowledge among university students in Jordan. Aims: This study aimed to evaluate the knowledge towards the nature of viruses and viral diseases among university students in Jordan. Metho…