Weimin Ye
YOU?
Author Swipe
View article: Mediterranean diet and risk of multiple sclerosis: A prospective cohort study
Mediterranean diet and risk of multiple sclerosis: A prospective cohort study Open
Background and Objectives: Although adherence to the Mediterranean diet has been reported to be inversely associated with risk of neurodegenerative disease, it is uncertain if this dietary pattern also reduces multiple sclerosis (MS) risk.…
View article: Machine learning-driven analysis of occupational heat exposure and metabolic associated fatty liver disease in petrochemical workers
Machine learning-driven analysis of occupational heat exposure and metabolic associated fatty liver disease in petrochemical workers Open
Chronic occupational heat exposure is a significant risk factor for MAFLD among petrochemical workers, particularly when combined with chemical exposures.
View article: Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis
Deciphering the role of complement system genes in pancreatic cancer susceptibility and prognosis Open
Pancreatic ductal adenocarcinoma (PDAC) genetic susceptibility is partially identified. The complement system (CS) influences carcinogenesis and participates in immunological defense and homeostasis; however, its role in PDAC genetic susce…
View article: Association between occupational heat exposure and early renal dysfunction among Chinese petrochemical workers: a combined machine learning and WQS modeling study
Association between occupational heat exposure and early renal dysfunction among Chinese petrochemical workers: a combined machine learning and WQS modeling study Open
Objective To investigate the association between occupational heat exposure and hyperuricemia among petrochemical workers. Methods We retrospectively analyzed the association between workplace heat exposure and hyperuricemia by using 10 ye…
View article: Hospital-treated infectious diseases and the risk of epilepsy in older age
Hospital-treated infectious diseases and the risk of epilepsy in older age Open
Infectious diseases are known to trigger acute seizures, but their long-term impact on epilepsy, especially in later life, is unclear. We conducted nested case–control studies of newly diagnosed epilepsy after age 50 in the UK Biobank (2,4…
View article: The comprehensive oral microbiome landscape unveils its interplay with poor oral health in esophageal squamous cell carcinoma risk
The comprehensive oral microbiome landscape unveils its interplay with poor oral health in esophageal squamous cell carcinoma risk Open
Growing evidence links poor oral health to an increased esophageal squamous cell carcinoma (ESCC) risk, with the oral microbiome recognized as a key contributor. However, human-based evidence remains limited. Here, we analyze salivary shot…
View article: Population-based nasopharyngeal carcinoma survival in southern China
Population-based nasopharyngeal carcinoma survival in southern China Open
Background Few population-based studies on nasopharyngeal carcinoma (NPC) prognosis exist. Such real-world data with complete follow-up are needed to enable accurate estimation of survival probabilities and monitor progress in early detect…
View article: The nomenclature of fatty liver disease and its impact on obesity traits, insulin resistance, and hepatic fibrosis
The nomenclature of fatty liver disease and its impact on obesity traits, insulin resistance, and hepatic fibrosis Open
The nomenclature of MAFLD covers a wider range of FLD than NAFLD and MASLD do, but the heterogeneity of AFLD is nonnegligible. Compared with MASLD, NAFLD remains a practical and efficient definition for large-scale population screening, es…
View article: Dietary patterns associated with hyperuricemia among the southeast coastal Chinese population
Dietary patterns associated with hyperuricemia among the southeast coastal Chinese population Open
Introduction Various foods or food groups and nutrients are correlated with serum uric acid levels. However, the findings were not consistent across different populations, and the mechanisms remain unclear. Methods In the baseline survey o…
View article: Evaluation of the diagnostic efficacy of different glycemic markers and insulin indices for diabetes mellitus in a general population
Evaluation of the diagnostic efficacy of different glycemic markers and insulin indices for diabetes mellitus in a general population Open
It is recommended that 2h PG and HbA1c should be used in population-based studies. The disposition index and TyG could potentially be used as DM predictors.
View article: Accurate fatty liver disease diagnosis with a multi-source feature fusion model on the segmented tongue image dataset
Accurate fatty liver disease diagnosis with a multi-source feature fusion model on the segmented tongue image dataset Open
This study developed an automated and explainable method for tongue diagnosis that facilitated the low-cost, speedy screening of FLD in large-scale populations, and contributed the largest public dataset to support future modeling research…
View article: Exogenous chemical exposures and metabolic disruptions in hyperuricemia: a multi-omics mediation study
Exogenous chemical exposures and metabolic disruptions in hyperuricemia: a multi-omics mediation study Open
In summary, hyperuricemia is related to the interplay of environmental exposures and individual genetic susceptibility, with metabolic dysregulation serving as a crucial mediating link. These findings offer novel insights into the potentia…
View article: Prevalence of thyroid nodules and canceration risk assessment in TIRADS, and their relationships to obesity and dysglycemia
Prevalence of thyroid nodules and canceration risk assessment in TIRADS, and their relationships to obesity and dysglycemia Open
Objective To describe the prevalence of thyroid nodules (TNs), their ultrasonographic characteristics, and the cancer risk assessment using the Thyroid Imaging Reporting and Data System (TIRADS) in a natural population, while also explorin…
View article: TyG Index and Related Indices Predicting Hypertension: Mediation by Neutrophil-to-Lymphocyte Ratio in Multiple Chinese Cohorts
TyG Index and Related Indices Predicting Hypertension: Mediation by Neutrophil-to-Lymphocyte Ratio in Multiple Chinese Cohorts Open
Background: Hypertension remains a leading cause of cardiovascular morbidity and mortality globally, and insulin resistance (IR) and systemic inflammation are implicated in the pathogenesis of hypertension. Limited evidence exists on the p…
View article: Development and validation of an integrative 54 biomarker-based risk identification model for multi-cancer in 42,666 individuals: a population-based prospective study to guide advanced screening strategies
Development and validation of an integrative 54 biomarker-based risk identification model for multi-cancer in 42,666 individuals: a population-based prospective study to guide advanced screening strategies Open
Background Early identification of high-risk individuals is crucial for optimizing cancer screening, particularly when considering expensive and invasive methods such as multi-omics technologies and endoscopic procedures. However, developi…
View article: The association between poor dental health and gastric cancer risk: a nationwide cohort and sibling-controlled study
The association between poor dental health and gastric cancer risk: a nationwide cohort and sibling-controlled study Open
Background Poor dental health has been linked to an increased risk of gastric cancer (GC), but previous studies were limited by their retrospective design and relatively small sample size. Methods We followed a nationwide cohort of 5,888,0…
View article: Association of circulating immuno-oncology biomarkers with breast cancer risk: insights from two prospective cohorts
Association of circulating immuno-oncology biomarkers with breast cancer risk: insights from two prospective cohorts Open
Immuno-oncology biomarkers are promising tools for cancer risk assessment and early detection. To identify and validate their associations with breast cancer, nested case-control studies within the Taizhou Longitudinal Study (TZL) cohort a…
View article: Interstitial Lung Disease and Risk of Lung Cancer
Interstitial Lung Disease and Risk of Lung Cancer Open
Importance An association between interstitial lung disease (ILD) and lung cancer has been hypothesized but never established. To date, whether this potential association persists after controlling for genetic factors has not been addresse…
View article: A genome-wide association study integrated with single-cell and bulk profiles uncovers susceptibility genes for nasopharyngeal carcinoma involved in tumorigenesis via regulation of T cells
A genome-wide association study integrated with single-cell and bulk profiles uncovers susceptibility genes for nasopharyngeal carcinoma involved in tumorigenesis via regulation of T cells Open
This study uncovers novel nasopharyngeal carcinoma susceptibility genes and their functional cell types, which improves the understanding of nasopharyngeal carcinoma genetic etiology.
View article: Temporal trends in surgical treatment of inflammatory bowel disease following introduction of biological drugs in Norway and Sweden
Temporal trends in surgical treatment of inflammatory bowel disease following introduction of biological drugs in Norway and Sweden Open
Objective The advent of biological drugs has revolutionised management of inflammatory bowel disease (IBD). However, the extent to which these novel pharmacological drugs have reduced the need for surgical treatment remains incompletely qu…
View article: A polarized view of the young pulsar wind nebula 3C 58 with IXPE
A polarized view of the young pulsar wind nebula 3C 58 with IXPE Open
Pulsar wind nebulae (PWNe) are among the most efficient particle accelerators in the Universe; however, the physical conditions and magnetic geometry in their inner regions remain poorly understood. X-ray polarization now provides a unique…
View article: Comparison of gastric microbiota in patients with different gastric lesions in high and low risk areas of gastric cancer
Comparison of gastric microbiota in patients with different gastric lesions in high and low risk areas of gastric cancer Open
This comparative analysis highlights the potential impact of the gastric microbiome in the development of GC and suggests that regional differences in microbial profiles may provide clues to the varying incidence rates of GC.
View article: Dietary patterns associated with benign breast nodules by subtypes: a cross-sectional study in southeast China
Dietary patterns associated with benign breast nodules by subtypes: a cross-sectional study in southeast China Open
Background Dietary patterns influence women's risk of breast cancer, but few studies have investigated the association with benign breast nodules, a well-established risk factor for breast cancer, especially by subtypes of the disease. Met…