Weimin Ye
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View article: Machine learning-driven analysis of occupational heat exposure and metabolic associated fatty liver disease in petrochemical workers
Machine learning-driven analysis of occupational heat exposure and metabolic associated fatty liver disease in petrochemical workers Open
View article: Supplementary Figure from Poor Oral Health and Esophageal Cancer Risk: A Nationwide Cohort Study
Supplementary Figure from Poor Oral Health and Esophageal Cancer Risk: A Nationwide Cohort Study Open
Supplementary Figure from Poor Oral Health and Esophageal Cancer Risk: A Nationwide Cohort Study
View article: Data from Poor Oral Health and Esophageal Cancer Risk: A Nationwide Cohort Study
Data from Poor Oral Health and Esophageal Cancer Risk: A Nationwide Cohort Study Open
Background:Previous research indicates that poor dental health increases risks for certain types of cancers, including esophageal cancer. This study aimed to investigate the association with esophageal cancer using Swedish Dental Health Re…
View article: Association between occupational heat exposure and early renal dysfunction among Chinese petrochemical workers: a combined machine learning and WQS modeling study
Association between occupational heat exposure and early renal dysfunction among Chinese petrochemical workers: a combined machine learning and WQS modeling study Open
Objective To investigate the association between occupational heat exposure and hyperuricemia among petrochemical workers. Methods We retrospectively analyzed the association between workplace heat exposure and hyperuricemia by using 10 ye…
View article: Hospital-treated infectious diseases and the risk of epilepsy in older age
Hospital-treated infectious diseases and the risk of epilepsy in older age Open
View article: The comprehensive oral microbiome landscape unveils its interplay with poor oral health in esophageal squamous cell carcinoma risk
The comprehensive oral microbiome landscape unveils its interplay with poor oral health in esophageal squamous cell carcinoma risk Open
Growing evidence links poor oral health to an increased esophageal squamous cell carcinoma (ESCC) risk, with the oral microbiome recognized as a key contributor. However, human-based evidence remains limited. Here, we analyze salivary shot…
View article: Population-based nasopharyngeal carcinoma survival in southern China
Population-based nasopharyngeal carcinoma survival in southern China Open
Background Few population-based studies on nasopharyngeal carcinoma (NPC) prognosis exist. Such real-world data with complete follow-up are needed to enable accurate estimation of survival probabilities and monitor progress in early detect…
View article: The nomenclature of fatty liver disease and its impact on obesity traits, insulin resistance, and hepatic fibrosis
The nomenclature of fatty liver disease and its impact on obesity traits, insulin resistance, and hepatic fibrosis Open
View article: Associations between metabolic dysfunction-associated fatty liver disease and carotid and femoral atherosclerosis: a population-based cross-sectional study
Associations between metabolic dysfunction-associated fatty liver disease and carotid and femoral atherosclerosis: a population-based cross-sectional study Open
MAFLD, especially DM-MAFLD, may increase the risk of atherosclerosis (particularly in the carotid arteries). Furthermore, individual and lifestyle factors may further affect this risk.
View article: Dietary patterns associated with hyperuricemia among the southeast coastal Chinese population
Dietary patterns associated with hyperuricemia among the southeast coastal Chinese population Open
Introduction Various foods or food groups and nutrients are correlated with serum uric acid levels. However, the findings were not consistent across different populations, and the mechanisms remain unclear. Methods In the baseline survey o…
View article: Evaluation of the diagnostic efficacy of different glycemic markers and insulin indices for diabetes mellitus in a general population
Evaluation of the diagnostic efficacy of different glycemic markers and insulin indices for diabetes mellitus in a general population Open
It is recommended that 2h PG and HbA1c should be used in population-based studies. The disposition index and TyG could potentially be used as DM predictors.
View article: Accurate fatty liver disease diagnosis with a multi-source feature fusion model on the segmented tongue image dataset
Accurate fatty liver disease diagnosis with a multi-source feature fusion model on the segmented tongue image dataset Open
This study developed an automated and explainable method for tongue diagnosis that facilitated the low-cost, speedy screening of FLD in large-scale populations, and contributed the largest public dataset to support future modeling research…
View article: Exogenous chemical exposures and metabolic disruptions in hyperuricemia: a multi-omics mediation study
Exogenous chemical exposures and metabolic disruptions in hyperuricemia: a multi-omics mediation study Open
In summary, hyperuricemia is related to the interplay of environmental exposures and individual genetic susceptibility, with metabolic dysregulation serving as a crucial mediating link. These findings offer novel insights into the potentia…
View article: Prevalence of thyroid nodules and canceration risk assessment in TIRADS, and their relationships to obesity and dysglycemia
Prevalence of thyroid nodules and canceration risk assessment in TIRADS, and their relationships to obesity and dysglycemia Open
Objective To describe the prevalence of thyroid nodules (TNs), their ultrasonographic characteristics, and the cancer risk assessment using the Thyroid Imaging Reporting and Data System (TIRADS) in a natural population, while also explorin…
View article: TyG Index and Related Indices Predicting Hypertension: Mediation by Neutrophil-to-Lymphocyte Ratio in Multiple Chinese Cohorts
TyG Index and Related Indices Predicting Hypertension: Mediation by Neutrophil-to-Lymphocyte Ratio in Multiple Chinese Cohorts Open
Background: Hypertension remains a leading cause of cardiovascular morbidity and mortality globally, and insulin resistance (IR) and systemic inflammation are implicated in the pathogenesis of hypertension. Limited evidence exists on the p…
View article: A Multi-Omics Model Predicting Acute Hematologic Toxicity (HT) in Locally Advanced Cervical Cancer Undergoing External-Beam Radiotherapy
A Multi-Omics Model Predicting Acute Hematologic Toxicity (HT) in Locally Advanced Cervical Cancer Undergoing External-Beam Radiotherapy Open
View article: Development and validation of an integrative 54 biomarker-based risk identification model for multi-cancer in 42,666 individuals: a population-based prospective study to guide advanced screening strategies
Development and validation of an integrative 54 biomarker-based risk identification model for multi-cancer in 42,666 individuals: a population-based prospective study to guide advanced screening strategies Open
View article: Shared genetic architecture between eating disorders, mental health conditions, and cardiometabolic diseases: a comprehensive population-wide study across two countries
Shared genetic architecture between eating disorders, mental health conditions, and cardiometabolic diseases: a comprehensive population-wide study across two countries Open
View article: The association between poor dental health and gastric cancer risk: a nationwide cohort and sibling-controlled study
The association between poor dental health and gastric cancer risk: a nationwide cohort and sibling-controlled study Open
View article: Association of circulating immuno-oncology biomarkers with breast cancer risk: insights from two prospective cohorts
Association of circulating immuno-oncology biomarkers with breast cancer risk: insights from two prospective cohorts Open
View article: Pharyngeal squamous cell carcinoma and risk of later esophageal squamous cell carcinoma – A nationwide population-based matched case-control study
Pharyngeal squamous cell carcinoma and risk of later esophageal squamous cell carcinoma – A nationwide population-based matched case-control study Open
View article: Interstitial Lung Disease and Risk of Lung Cancer
Interstitial Lung Disease and Risk of Lung Cancer Open
Importance An association between interstitial lung disease (ILD) and lung cancer has been hypothesized but never established. To date, whether this potential association persists after controlling for genetic factors has not been addresse…
View article: A genome-wide association study integrated with single-cell and bulk profiles uncovers susceptibility genes for nasopharyngeal carcinoma involved in tumorigenesis via regulation of T cells
A genome-wide association study integrated with single-cell and bulk profiles uncovers susceptibility genes for nasopharyngeal carcinoma involved in tumorigenesis via regulation of T cells Open
This study uncovers novel nasopharyngeal carcinoma susceptibility genes and their functional cell types, which improves the understanding of nasopharyngeal carcinoma genetic etiology.
View article: Shared genetic architecture between eating disorders, mental health conditions, and cardiometabolic diseases: a comprehensive population-wide study across two countries
Shared genetic architecture between eating disorders, mental health conditions, and cardiometabolic diseases: a comprehensive population-wide study across two countries Open
View article: Temporal trends in surgical treatment of inflammatory bowel disease following introduction of biological drugs in Norway and Sweden
Temporal trends in surgical treatment of inflammatory bowel disease following introduction of biological drugs in Norway and Sweden Open
Objective The advent of biological drugs has revolutionised management of inflammatory bowel disease (IBD). However, the extent to which these novel pharmacological drugs have reduced the need for surgical treatment remains incompletely qu…
View article: A polarized view of the young pulsar wind nebula 3C 58 with IXPE
A polarized view of the young pulsar wind nebula 3C 58 with IXPE Open
Pulsar wind nebulae (PWNe) are among the most efficient particle accelerators in the Universe; however, the physical conditions and magnetic geometry in their inner regions remain poorly understood. X-ray polarization now provides a unique…
View article: Comparison of gastric microbiota in patients with different gastric lesions in high and low risk areas of gastric cancer
Comparison of gastric microbiota in patients with different gastric lesions in high and low risk areas of gastric cancer Open
This comparative analysis highlights the potential impact of the gastric microbiome in the development of GC and suggests that regional differences in microbial profiles may provide clues to the varying incidence rates of GC.
View article: Dietary patterns associated with benign breast nodules by subtypes: a cross-sectional study in southeast China
Dietary patterns associated with benign breast nodules by subtypes: a cross-sectional study in southeast China Open
Background Dietary patterns influence women's risk of breast cancer, but few studies have investigated the association with benign breast nodules, a well-established risk factor for breast cancer, especially by subtypes of the disease. Met…
View article: Temporal trends in characteristics and management of inflammatory bowel disease
Temporal trends in characteristics and management of inflammatory bowel disease Open
Our findings suggest a shift towards more frequent endoscopy, increased use of immunosuppressants and biologics, and decreased colon resection rates in recent periods.
View article: The Mediation Role of Insulin Resistance and Chronic Systemic Inflammation in the Association Between Obesity and NAFLD: Two Cross-Sectional and a Mendelian Randomization Study
The Mediation Role of Insulin Resistance and Chronic Systemic Inflammation in the Association Between Obesity and NAFLD: Two Cross-Sectional and a Mendelian Randomization Study Open
Through two population-based studies and MR, we found the causal mediation roles of IR and inflammation in the association between obesity and NAFLD, in which HOMA-IR and CRP showed stable, significant mediation effects. Furthermore, HOMA-…