Young Kyung Lim
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View article: Radial excitations and their potential impact on Fermi $β$-decay rates
Radial excitations and their potential impact on Fermi $β$-decay rates Open
We investigate the contribution of radial excitations to Fermi $β$-decay matrix element. To this end, exact no-core shell model calculations are performed for the mirror $β$ decay of tritium, where full convergence can be achieved on an or…
View article: Impact of Phosphate Variability in Patients Undergoing Hemodialysis
Impact of Phosphate Variability in Patients Undergoing Hemodialysis Open
Background: There are few studies investigating the relationship between phosphate level variability and clinical prognosis in hemodialysis (HD) patients. This study aimed to evaluate the impact of phosphate variability on clinical outcome…
View article: The Association Between Erythropoiesis Resistance Index and Clinical Outcomes in Hemodialysis Patients: A Nationwide Study
The Association Between Erythropoiesis Resistance Index and Clinical Outcomes in Hemodialysis Patients: A Nationwide Study Open
Background: Although erythropoiesis-stimulating agent (ESA) therapy is fundamental for correcting anemia, excessive ESA administration is associated with increased risks. This study aimed to investigate the impact of the erythropoietin res…
View article: Dosimetric Evaluation of Large-area Proton Minibeam Radiation Therapy System for Clinical Applications
Dosimetric Evaluation of Large-area Proton Minibeam Radiation Therapy System for Clinical Applications Open
Proton minibeam radiation therapy (pMBRT) has emerged as a promising radiation treatment modality, offering enhanced tissue-sparing effects compared to conventional proton therapy. For clinical application, we developed a pMBRT system with…
View article: Feasibility study for the development of multilayered solar cells for proton linear energy transfer depth profile measurement
Feasibility study for the development of multilayered solar cells for proton linear energy transfer depth profile measurement Open
Background Previous study proposed a method to measure linear energy transfer (LET) at specific points using the quenching magnitude of thin film solar cells. This study was conducted to propose a more advanced method for measuring the LET…
View article: Feature Importance Analysis of a Deep Learning Model for Predicting Late Bladder Toxicity Occurrence in Uterine Cervical Cancer Patients
Feature Importance Analysis of a Deep Learning Model for Predicting Late Bladder Toxicity Occurrence in Uterine Cervical Cancer Patients Open
(1) In this study, we developed a deep learning (DL) model that can be used to predict late bladder toxicity. (2) We collected data obtained from 281 uterine cervical cancer patients who underwent definitive radiation therapy. The DL model…
View article: Interobserver Variability Prediction of Primary Gross Tumor in a Patient with Non-Small Cell Lung Cancer
Interobserver Variability Prediction of Primary Gross Tumor in a Patient with Non-Small Cell Lung Cancer Open
This research addresses the problem of interobserver variability (IOV), in which different oncologists manually delineate varying primary gross tumor volume (pGTV) contours, adding risk to targeted radiation treatments. Thus, a method of I…
View article: Assessment of a Therapeutic X-ray Radiation Dose Measurement System Based on a Flexible Copper Indium Gallium Selenide Solar Cell
Assessment of a Therapeutic X-ray Radiation Dose Measurement System Based on a Flexible Copper Indium Gallium Selenide Solar Cell Open
Several detectors have been developed to measure radiation doses during radiotherapy. However, most detectors are not flexible. Consequently, the airgaps between the patient surface and detector could reduce the measurement accuracy. Thus,…
View article: Dose Profile Modulation of Proton Minibeam for Clinical Application
Dose Profile Modulation of Proton Minibeam for Clinical Application Open
The feasibility of proton minibeam radiation therapy (pMBRT) using a multislit collimator (MSC) and a scattering device was evaluated for clinical use at a clinical proton therapy facility. We fabricated, through Monte Carlo (MC) simulatio…
View article: Surface Waves in a Relativistic Plasma Stream Propagating in a Duct: Kinetic Theory
Surface Waves in a Relativistic Plasma Stream Propagating in a Duct: Kinetic Theory Open
Dispersion relation of surface waves generated by a relativistic plasma stream in an infinite duct surrounded by vacuum is derived by means of relativistic Vlasov equation. The kinematic boundary condition imposed on the distribution funct…
View article: Beam Angle Optimization for Double-Scattering Proton Delivery Technique Using an Eclipse Application Programming Interface and Convolutional Neural Network
Beam Angle Optimization for Double-Scattering Proton Delivery Technique Using an Eclipse Application Programming Interface and Convolutional Neural Network Open
To automatically identify optimal beam angles for proton therapy configured with the double-scattering delivery technique, a beam angle optimization method based on a convolutional neural network (BAODS-Net) is proposed. Fifty liver plans …
View article: Brachytherapy: A Comprehensive Review
Brachytherapy: A Comprehensive Review Open
Other SectionsAbstractIntroductionRadiation Sources for BrachytherapyBrachytherapy ApplicatorsImaging for BrachytherapyDose OptimizationTreatment Quality ManagementTreatment TechniquesTreatment SitesConclusionsConflicts of InterestAvailabi…
View article: Evaluation of the dosimetric effect of scattered protons in clinical practice in passive scattering proton therapy
Evaluation of the dosimetric effect of scattered protons in clinical practice in passive scattering proton therapy Open
The present study verified and evaluated the dosimetric effects of protons scattered from a snout and an aperture in clinical practice, when a range compensator was included. The dose distribution calculated by a treatment planning system …
View article: Feasibility Study of Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy
Feasibility Study of Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy Open
Brachytherapy is an important technique to increase the overall survival of cervical cancer patients. However, a possible shift of the applicators in relation to the target and organs at risk may occur between imaging and treatment. Withou…
View article: Deep Learning Method for Prediction of Patient-Specific Dose Distribution in Breast Cancer
Deep Learning Method for Prediction of Patient-Specific Dose Distribution in Breast Cancer Open
BackgroundPatient-specific dose prediction improves the efficiency and quality of radiation treatment planning and reduces the time required to find the optimal plan. In this study, a patient-specific dose prediction model was developed fo…
View article: Preclinical evaluation of radiation therapy of <i>BRCA1</i>-associated mammary tumors using a mouse model
Preclinical evaluation of radiation therapy of <i>BRCA1</i>-associated mammary tumors using a mouse model Open
Although germline mutations in BRCA1 highly predispose women towards breast and ovarian cancer, few substantial improvements in preventing or treating such cancers have been made. Importantly, BRCA1 function is closely associated with DNA …
View article: Plan optimization with L0-norm and group sparsity constraints for a new rotational, intensity-modulated brachytherapy for cervical cancer
Plan optimization with L0-norm and group sparsity constraints for a new rotational, intensity-modulated brachytherapy for cervical cancer Open
The aim of this work is to build a framework that comprehends inverse planning procedure and plan optimization algorithm tailored to a novel directional beam intensity-modulated brachytherapy (IMBT) of cervical cancer using a rotatable, si…
View article: Facial expression monitoring system for predicting patient’s sudden movement during radiotherapy using deep learning
Facial expression monitoring system for predicting patient’s sudden movement during radiotherapy using deep learning Open
Purpose Imaging, breath‐holding/gating, and fixation devices have been developed to minimize setup errors so that the prescribed dose can be exactly delivered to the target volume in radiotherapy. Despite these efforts, additional patient …
View article: Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy
Robust Optimization to Reduce Dose Delivery Uncertainty by Potential Applicator Displacements for a Cervix Brachytherapy Open
Background Applicator displacement during brachytherapy treatment for cervical cancer leads to a drastic change in dose distribution. Hence, applicator displacement uncertainty is of significant relevance within the distribution of dose pr…
View article: Radiotherapy Risk Estimation Based on Expert Group Survey
Radiotherapy Risk Estimation Based on Expert Group Survey Open
Although current quality assurance systems such as Task Group 142 of the American Association of Physicists in Medicine and other methods used for radiotherapy have greatly contributed to decreasing radiotherapy incidents, there is still s…