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View article: Development of an open-source tool for risk assessment in pulmonary endarterectomy
Development of an open-source tool for risk assessment in pulmonary endarterectomy Open
Background Risk prediction tools are routinely utilised in cardiothoracic surgery but have not been developed for pulmonary endarterectomy (PEA). There is no data on whether patients undergoing PEA may benefit from a tailored risk modellin…
View article: S39 Long term outcome in chronic thromboembolic pulmonary hypertension in the multimodality treatment era: a UK national cohort analysis
S39 Long term outcome in chronic thromboembolic pulmonary hypertension in the multimodality treatment era: a UK national cohort analysis Open
Introduction and Objectives Chronic thromboembolic pulmonary hypertension (CTEPH) treatment is multimodal and includes medical therapy, pulmonary endarterectomy (PEA) and balloon pulmonary angioplasty (BPA). However, there is limited outco…
View article: Balloon pulmonary angioplasty outcomes in patients previously treated by pulmonary endarterectomy surgery are inferior to those of inoperable patients
Balloon pulmonary angioplasty outcomes in patients previously treated by pulmonary endarterectomy surgery are inferior to those of inoperable patients Open
Pulmonary endarterectomy (PEA) may not achieve full clearance of vascular obstructions in patients with more distal chronic thromboembolic pulmonary hypertension (CTEPH). Balloon pulmonary angioplasty (BPA) may be indicated to treat these …
View article: Early experience with pulmonary endarterectomy in Bulgaria—case series
Early experience with pulmonary endarterectomy in Bulgaria—case series Open
We present our results of initial experience with PEA in Bulgaria with encouraging results. Our work shows that inter-European relationship for healthcare can be productive and offer safe treatment on local level.
View article: Acute lung injury after balloon pulmonary angioplasty results in a similar haemodynamic response and possible clinical advantage at follow‐up
Acute lung injury after balloon pulmonary angioplasty results in a similar haemodynamic response and possible clinical advantage at follow‐up Open
Acute lung injury (ALI) is a common but poorly defined and understood complication of balloon pulmonary angioplasty (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH). Little data are available on the medium term clinical outc…
View article: Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry
Post-infarction ventricular septal defect: percutaneous or surgical management in the UK national registry Open
Aims Post-infarction ventricular septal defect (PIVSD) is a mechanical complication of acute myocardial infarction (AMI) with a poor prognosis. Surgical repair is the mainstay of treatment, although percutaneous closure is increasingly und…
View article: Acute aortic regurgitation due to fibrous strand rupture
Acute aortic regurgitation due to fibrous strand rupture Open
A 60‐year‐old male presented with sudden onset chest pain and pulmonary edema. The investigation confirmed torrential aortic regurgitation of a bicuspid valve. At surgery, a ruptured fibrous strand was identified which had been supporting …
View article: Acute aortic regurgitation due to chordae tendineae rupture
Acute aortic regurgitation due to chordae tendineae rupture Open
A 60-year-old male presented with sudden onset chest pain and pulmonary oedema. Investigation confirmed torrential aortic regurgitation of a bicuspid valve. At surgery a ruptured chordae tendineae was identified which had been supporting t…
View article: Pulmonary thromboendarterectomy—the Royal Papworth experience
Pulmonary thromboendarterectomy—the Royal Papworth experience Open
There was a consistent increase in activity and significant improvement in outcomes between the first and last quartiles of activity studied.
View article: Rising COVID-19 related acute pulmonary emboli but falling national chronic thromboembolic pulmonary hypertension referrals from a large national dataset.
Rising COVID-19 related acute pulmonary emboli but falling national chronic thromboembolic pulmonary hypertension referrals from a large national dataset. Open
The average rate of new #CTEPH referrals has dropped by 32% in the UK during the pandemic, despite the high incidence of #COVID19 related pulmonary emboli. There have been no recorded new cases of CTEPH caused by COVID-19. A prospective st…
View article: Rising COVID-19 related acute pulmonary emboli but falling national chronic thromboembolic pulmonary hypertension referrals from a large national dataset
Rising COVID-19 related acute pulmonary emboli but falling national chronic thromboembolic pulmonary hypertension referrals from a large national dataset Open
The average rate of new #CTEPH referrals has dropped by 32% in the UK during the pandemic, despite the high incidence of #COVID19 related pulmonary emboli. There have been no recorded new cases of CTEPH caused by COVID-19. A prospective st…
View article: Self-induced pneumatically powered nail removed from the mediastinum without opening the chest
Self-induced pneumatically powered nail removed from the mediastinum without opening the chest Open
A patient in his 50s shot himself with a nail gun presented to our center for further management after initial resuscitation in district general hospital. An echocardiogram report demonstrated mild pericardial effusion; he was hemodynamica…
View article: CAMPHOR score: patient-reported outcomes are improved by pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension
CAMPHOR score: patient-reported outcomes are improved by pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension Open
Background Pulmonary endarterectomy (PEA) is the recommended treatment for eligible patients with chronic thromboembolic pulmonary hypertension (CTEPH). The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) score is an internationa…
View article: The COVID-19 Pandemic and Acute Aortic Dissection: an unintended consequence?
The COVID-19 Pandemic and Acute Aortic Dissection: an unintended consequence? Open
The COVID-19 pandemic has had a profound impact on healthcare worldwide. Emergency presentations to hospital unrelated to COVID-19 have generally, significantly reduced. At our centre we have observed a substantial surge in the number of p…
View article: Deprescribing practices for anticonvulsants after benign seizures secondary to high-dose tranexamic acid in a single, large UK cardiothoracic centre
Deprescribing practices for anticonvulsants after benign seizures secondary to high-dose tranexamic acid in a single, large UK cardiothoracic centre Open
Deprescribing of anticonvulsants after benign seizures secondary to high-dose TXA is facilitated by verbal and written handover, which can be improved in our hospital. A detailed handover summary, as well as a discharge letter with clearly…
View article: The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension
The ADAMTS13–VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension Open
Chronic thromboembolic pulmonary hypertension (CTEPH) is an important consequence of pulmonary embolism that is associated with abnormalities in haemostasis. We investigated the ADAMTS13–von Willebrand factor (VWF) axis in CTEPH, including…
View article: Limitations of resting haemodynamics in chronic thromboembolic disease without pulmonary hypertension
Limitations of resting haemodynamics in chronic thromboembolic disease without pulmonary hypertension Open
There is renewed interest in the haemodynamic definitions of pulmonary hypertension (PH), reigniting an old debate about diagnostic thresholds [1]. Recent prospective data support work dating back over 40 years demonstrating patients with …
View article: The outcome of reoperative pulmonary endarterectomy surgery
The outcome of reoperative pulmonary endarterectomy surgery Open
OBJECTIVES: Pulmonary endarterectomy (PEA) is the treatment of choice for patients with chronic thromboembolic pulmonary hypertension (PH). Despite excellent outcomes following PEA, a small proportion of patients have residual proximal dis…
View article: Age should not be a barrier for pulmonary endarterectomy in carefully selected patients
Age should not be a barrier for pulmonary endarterectomy in carefully selected patients Open
Pulmonary endarterectomy (PEA) is the treatment of choice in operable chronic thromboembolic pulmonary hypertension (CTEPH) with excellent long-term outcomes [1]. It is a complex surgical procedure requiring cardiopulmonary bypass and remo…
View article: S50 Camphor score: sustained improvement in patient reported outcomes following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension
S50 Camphor score: sustained improvement in patient reported outcomes following pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension Open
Introduction The CAMPHOR (Cambridge Pulmonary Hypertension Outcome Review) score is an internationally validated patient reported outcome (PRO) measure for pulmonary hypertension, including chronic thromboembolic pulmonary hypertension (CT…
View article: S108 Genome-wide association study in chronic thromboembolic pulmonary hypertension reveals new insights into aetiology
S108 Genome-wide association study in chronic thromboembolic pulmonary hypertension reveals new insights into aetiology Open
Introduction Chronic thromboembolic pulmonary hypertension (CTEPH) is an infrequent but important complication of acute pulmonary embolism (PE). Thrombophilias and non-O blood groups are genetic risk factors for venous thromboembolism (VTE…
View article: S51 Patient pathway mapping of uk referrals to the national pulmonary endarterectomy mdt (june 2015 – may 2016)
S51 Patient pathway mapping of uk referrals to the national pulmonary endarterectomy mdt (june 2015 – may 2016) Open
Introduction Pulmonary endarterectomy (PEA) is the treatment of choice for Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and can be offered to selected patients with Chronic Thromboembolic Disease without pulmonary hypertension (CT…
View article: P184 Age should not be a barrier to pulmonary endarterectomy in carefully selected patients
P184 Age should not be a barrier to pulmonary endarterectomy in carefully selected patients Open
Introduction We previously reported that hospital survival in patients over 70 years undergoing pulmonary endarterectomy (PEA) was comparable to those under 70, albeit with longer hospital and intensive care unit (ICU) stays.1 Octogenarian…
View article: Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy
Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy Open
Background— Chronic thromboembolic pulmonary hypertension results from incomplete resolution of pulmonary emboli. Pulmonary endarterectomy (PEA) is potentially curative, but residual pulmonary hypertension following surgery is common and i…
View article: Pulmonary endarterectomy is effective and safe in patients with haemoglobinopathies and abnormal red blood cells: the Papworth experience
Pulmonary endarterectomy is effective and safe in patients with haemoglobinopathies and abnormal red blood cells: the Papworth experience Open
OBJECTIVES Patients with haemoglobinopathies and congenital haemolytic anaemia constitute a unique population more predisposed to developing chronic thromboembolic pulmonary hypertension (CTEPH). Although pulmonary endarterectomy (PEA) is …