Yenew Kebede
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View article: Genomic epidemiology uncovers the origin of the mpox epidemic in Sierra Leone
Genomic epidemiology uncovers the origin of the mpox epidemic in Sierra Leone Open
In January 2025, Sierra Leone reported its first mpox case in eight years, followed by a rapid nationwide surge that made it the epicenter of the continental mpox virus (MPXV) Clade IIb A.2.2 outbreak, with more than 5,000 confirmed cases …
View article: Monitoring SARS-CoV-2 variants in wastewater during periods of low clinical case surveillance in Ethiopia
Monitoring SARS-CoV-2 variants in wastewater during periods of low clinical case surveillance in Ethiopia Open
Wastewater-based genomic surveillance is a cost-effective approach for tracking outbreaks like severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A 2023 study in Addis Ababa, Ethiopia, revealed two infection waves in March and A…
View article: Bacteriology testing and antimicrobial resistance detection capacity of national tiered laboratory networks in sub-Saharan Africa: an analysis from 14 countries
Bacteriology testing and antimicrobial resistance detection capacity of national tiered laboratory networks in sub-Saharan Africa: an analysis from 14 countries Open
Fleming Fund, UK Aid, and US Centers for Disease Control and Prevention through the Training Programs in Epidemiology and Public Health Intervention Networks.
View article: Longitudinal wastewater-based surveillance of SARS-CoV-2 during 2023 in Ethiopia
Longitudinal wastewater-based surveillance of SARS-CoV-2 during 2023 in Ethiopia Open
Introduction Although wastewater-based epidemiology (WBE) successfully functioned as a tool for monitoring the coronavirus disease 2019 (COVID-19) pandemic globally, relatively little is known about its utility in low-income countries. Thi…
View article: Diagnostics for detection and surveillance of priority epidemic-prone diseases in Africa: an assessment of testing capacity and laboratory strengthening needs
Diagnostics for detection and surveillance of priority epidemic-prone diseases in Africa: an assessment of testing capacity and laboratory strengthening needs Open
In 2023, Africa experienced 180 public health emergencies, of which 90% were infectious diseases and 75% were related to zoonotic diseases. Testing capacity for epidemic-prone diseases is essential to enable rapid and accurate identificati…
View article: Establishing an early warning event management system at Africa CDC
Establishing an early warning event management system at Africa CDC Open
Africa is home to hotspots of disease emergence and re-emergence. To adequately detect and respond to these health threats, early warning systems inclusive of event-based surveillance (EBS) are needed. However, data systems to manage these…
View article: The Looming Threat of Dengue Fever: The Africa Context
The Looming Threat of Dengue Fever: The Africa Context Open
In Africa, compared to 2019, dengue infections have surged ninefold by December 2023, with over 270 000 cases and 753 deaths reported across 18 African Union (AU) Member States. This commentary synthesises the context of dengue outbreaks i…
View article: Diagnostics for detection and surveillance of priority epidemic-prone diseases in Africa: an assessment of testing capacity and laboratory strengthening needs
Diagnostics for detection and surveillance of priority epidemic-prone diseases in Africa: an assessment of testing capacity and laboratory strengthening needs Open
In 2023, Africa experienced 180 public health emergencies, of which 90% were infectious diseases and 75% were related to zoonotic diseases. Testing capacity for epidemic-prone diseases is essential to enable rapid and accurate identificati…
View article: Predictors of neonatal mortality among neonates admitted to the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital, Sidama regional state, Ethiopia
Predictors of neonatal mortality among neonates admitted to the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital, Sidama regional state, Ethiopia Open
Background Despite promising efforts, substantial deaths occurred during the neonatal period. According to estimates from the World Health Organization (WHO), Ethiopia is among the top 10 nations with the highest number of neonatal deaths …
View article: Tackling the twin threats of pandemics and climate change: An agenda for action.
Tackling the twin threats of pandemics and climate change: An agenda for action. Open
View article: Tackling the twin threats of pandemics and climate change: an agenda for action
Tackling the twin threats of pandemics and climate change: an agenda for action Open
No abstract available.
View article: Evaluating event-based surveillance capacity in Africa: Use of the Africa CDC scorecard, 2022–2023
Evaluating event-based surveillance capacity in Africa: Use of the Africa CDC scorecard, 2022–2023 Open
View article: Predictors of neonatal mortality among neonates admitted to the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital, Sidama regional state, Ethiopia
Predictors of neonatal mortality among neonates admitted to the neonatal intensive care unit at Hawassa University Comprehensive Specialized Hospital, Sidama regional state, Ethiopia Open
Background Despite promising efforts, substantial deaths occurred during the neonatal period. According to estimates from the World Health Organization(WHO), Ethiopia is among the top 10 nations with the highest number of neonatal deaths i…
View article: Africa CDC's blueprint to enhance early warning surveillance: accelerating implementation of event-based surveillance in Africa
Africa CDC's blueprint to enhance early warning surveillance: accelerating implementation of event-based surveillance in Africa Open
Event-based surveillance (EBS) is a core component of early warning surveillance. In 2018, Africa CDC developed the first edition of an event-based surveillance framework to guide African Union Member States in implementing EBS. Country ex…
View article: Insights into SARS-CoV-2 in Angola during the COVID-19 Peak: Molecular Epidemiology and Genome Surveillance
Insights into SARS-CoV-2 in Angola during the COVID-19 Peak: Molecular Epidemiology and Genome Surveillance Open
Background: In Angola, COVID-19 cases have been reported in all provinces, resulting in >105,000 cases and >1,900 deaths. However, no detailed genomic surveillance into the introduction and spread of the SARS-CoV-2 virus has been conducted…
View article: Building Integrated Testing Programs for Infectious Diseases
Building Integrated Testing Programs for Infectious Diseases Open
In the past 2 decades, testing services for diseases such as human immunodeficiency virus (HIV), tuberculosis, and malaria have expanded dramatically. Investments in testing capacity and supportive health systems have often been disease sp…
View article: Evaluating Event-Based Surveillance Capacity in Africa: Use of the Africa CDC Scorecard, 2022-2023
Evaluating Event-Based Surveillance Capacity in Africa: Use of the Africa CDC Scorecard, 2022-2023 Open
View article: Examining 7 years of implementing quality management systems in medical laboratories in <scp>sub‐Saharan</scp> Africa
Examining 7 years of implementing quality management systems in medical laboratories in <span>sub‐Saharan</span> Africa Open
Background Achievement of ISO15189 accreditation demonstrates competency of a laboratory to conduct testing. Three programmes were developed to facilitate achievement of accreditation in low‐ and middle‐income countries: Strengthening Labo…
View article: Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus
Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus Open
We propose a novel, non-discriminatory classification of monkeypox virus diversity. Together with the World Health Organization, we named three clades (I, IIa and IIb) in order of detection. Within IIb, the cause of the current global outb…
View article: Implementation of COVID-19 Laboratory Testing Certification Program (CoLTeP) in African Region
Implementation of COVID-19 Laboratory Testing Certification Program (CoLTeP) in African Region Open
Objectives: Coronavirus disease 2019 was declared a global pandemic in March 2020 with correct and early detection of cases using laboratory testing central to the response. Hence, the establishment of quality management systems and monito…
View article: The first and second waves of the COVID-19 pandemic in Africa: a cross-sectional study
The first and second waves of the COVID-19 pandemic in Africa: a cross-sectional study Open
View article: Genomic-informed pathogen surveillance in Africa: opportunities and challenges
Genomic-informed pathogen surveillance in Africa: opportunities and challenges Open
View article: Preparing national tiered laboratory systems and networks to advance diagnostics in Africa and meet the continent’s health agenda: Insights into priority areas for improvement
Preparing national tiered laboratory systems and networks to advance diagnostics in Africa and meet the continent’s health agenda: Insights into priority areas for improvement Open
No abstract available.
View article: Accelerating genomics-based surveillance for COVID-19 response in Africa
Accelerating genomics-based surveillance for COVID-19 response in Africa Open
View article: COVID-19 testing in Africa: lessons learnt
COVID-19 testing in Africa: lessons learnt Open
View article: Role of public-private partnerships in achieving UNAIDS HIV treatment targets
Role of public-private partnerships in achieving UNAIDS HIV treatment targets Open
View article: Combatting Global Infectious Diseases: A Network Effect of Specimen Referral Systems
Combatting Global Infectious Diseases: A Network Effect of Specimen Referral Systems Open
The recent Ebola virus outbreak in West Africa clearly demonstrated the critical role of laboratory systems and networks in responding to epidemics. Because of the huge challenges in establishing functional laboratories at all tiers of hea…
View article: Quality assurance for point-of-care testing: Ethiopia’s experience
Quality assurance for point-of-care testing: Ethiopia’s experience Open
No abstract available.
View article: Improved Specimen-Referral System and Increased Access to Quality Laboratory Services in Ethiopia: The Role of the Public-Private Partnership
Improved Specimen-Referral System and Increased Access to Quality Laboratory Services in Ethiopia: The Role of the Public-Private Partnership Open
This study highlights the feasibility and untapped potential of PPPs to strengthen laboratory systems. This planned and structured approach to improving specimen referral enhanced access to quality laboratory services.