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View article: <scp>miRNA</scp> Differential Expression Profile Analysis and Identification of Potential Key Genes in Active Tuberculosis
<span>miRNA</span> Differential Expression Profile Analysis and Identification of Potential Key Genes in Active Tuberculosis Open
Tuberculosis (TB), caused by Mycobacterium TB (MTB), remains a significant global health issue, particularly in developing nations. MicroRNAs (miRNAs) are non‐coding RNAs (ncRNAs) that modulate immune responses and play a pivotal role in t…
View article: La0.6Sr0.4Co0.2Fe0.8O3-∝ (LSCF) biosensor for diagnosing colorectal cancer: A quaternary alloy on an interdigitated electrode
La0.6Sr0.4Co0.2Fe0.8O3-∝ (LSCF) biosensor for diagnosing colorectal cancer: A quaternary alloy on an interdigitated electrode Open
Colorectal cancer (CRC) is a type of gastrointestinal cancer affecting the colon and rectum. It can metastasize to other parts of the body, making treatment more challenging. Early identification and treatment of CRC significantly enhance …
View article: Exploring the ancient roots and modern global brews of tea and herbal beverages: A comprehensive review of origins, types, health benefits, market dynamics, and future trends
Exploring the ancient roots and modern global brews of tea and herbal beverages: A comprehensive review of origins, types, health benefits, market dynamics, and future trends Open
Tea, a culturally significant beverage, originated around 2700 B.C. in ancient Chinese civilization, with a profound understanding of its therapeutic properties. Herbal medicines from diverse plant sources have been esteemed for their phyt…
View article: Plant bioactive compounds driven microRNAs (miRNAs): A potential source and novel strategy targeting gene and cancer therapeutics
Plant bioactive compounds driven microRNAs (miRNAs): A potential source and novel strategy targeting gene and cancer therapeutics Open
Irrespective of medical technology improvements, cancer ranks among the leading causes of mortality worldwide. Although numerous cures and treatments exist, creating alternative cancer therapies with fewer adverse side effects is vital. Si…
View article: Exploring MiR-484 Regulation by Polyalthia longifolia: A Promising Biomarker and Therapeutic Target in Cervical Cancer through Integrated Bioinformatics and an In Vitro Analysis
Exploring MiR-484 Regulation by Polyalthia longifolia: A Promising Biomarker and Therapeutic Target in Cervical Cancer through Integrated Bioinformatics and an In Vitro Analysis Open
Background: MiR-484, implicated in various carcinomas, holds promise as a prognostic marker, yet its relevance to cervical cancer (CC) remains unclear. Our prior study demonstrated the Polyalthia longifolia downregulation of miR-484, inhib…
View article: Based on In Vitro and 3D Epidermal Skin Model: The Efficacy of Bletilla Striata Extract for Skin Care
Based on In Vitro and 3D Epidermal Skin Model: The Efficacy of Bletilla Striata Extract for Skin Care Open
Introduction: Bletilla Striata (Thunb. ex A. Murray) Rchb. f.) Is a native herb of the orchidaceae family. Modern pharmacological activity studies have shown that Bletilla striata mainly has pharmacological activities such as promoting blo…
View article: Dual-probe sandwich for Lewy body detection on nano-composite modified dielectric surface to determine Parkinson's disease
Dual-probe sandwich for Lewy body detection on nano-composite modified dielectric surface to determine Parkinson's disease Open
Parkinson's disorder (PD) is a chronic and central nervous system disorder that occurs when neurons in the area of the brain impairs or dies, in particular, it affects the dopamine-producing neurons. People having PD also loose chemical me…
View article: Standardized Polyalthia longifolia leaf extract induces the apoptotic HeLa cells death via microRNA regulation: identification, validation, and therapeutic potential
Standardized Polyalthia longifolia leaf extract induces the apoptotic HeLa cells death via microRNA regulation: identification, validation, and therapeutic potential Open
Polyalthia longifolia var. angustifolia Thw. (Annonaceae), is a famous traditional medicinal plant in Asia. Ample data specifies that the medicinal plant P. longifolia has anticancer activity; however, the detailed mechanisms of action sti…
View article: Generation of microcrystalline cellulose from cotton waste and its properties
Generation of microcrystalline cellulose from cotton waste and its properties Open
Microcrystalline cellulose (MCC) is a green material that has widespread applications in pharmaceuticals, food, cosmetics, and other industries because of its biocompatibility, biodegradability, hydrophilicity, and acid-insolubility. In th…
View article: Clusterin and Its Isoforms in Oral Squamous Cell Carcinoma and Their Potential as Biomarkers: A Comprehensive Review
Clusterin and Its Isoforms in Oral Squamous Cell Carcinoma and Their Potential as Biomarkers: A Comprehensive Review Open
Oral squamous cell carcinoma (OSCC) is a prevalent type of head and neck cancer, ranked as the sixth most common cancer worldwide, accounting for approximately 300,000 new cases and 145,000 deaths annually. Early detection using biomarkers…
View article: Bio-Enzyme Hybrid with Nanomaterials: A Potential Cargo as Sustainable Biocatalyst
Bio-Enzyme Hybrid with Nanomaterials: A Potential Cargo as Sustainable Biocatalyst Open
With advancements in bionanotechnology, the field of nanobiocatalysts has undergone rapid growth and revolutionized various nanomaterials as novel and fascinating nanocarriers for enzyme immobilization. Nanotubes, nanofibers, nanopores, na…
View article: Synergistic Antimicrobial Activity of Ceftriaxone and Polyalthia longifolia Methanol (MEPL) Leaf Extract against Methicillin-Resistant Staphylococcus aureus and Modulation of mecA Gene Presence
Synergistic Antimicrobial Activity of Ceftriaxone and Polyalthia longifolia Methanol (MEPL) Leaf Extract against Methicillin-Resistant Staphylococcus aureus and Modulation of mecA Gene Presence Open
Medicinal plants are an essential source of traditional curatives for numerous skin diseases. Polyalthia longifolia (Sonn.) Thwaites (Annonaceae family) is a medicinal plant used to cure skin illnesses. P. longifolia is usually applied in …
View article: Green Carbon Dots: Synthesis, Characterization, Properties and Biomedical Applications
Green Carbon Dots: Synthesis, Characterization, Properties and Biomedical Applications Open
Carbon dots (CDs) are a new category of crystalline, quasi-spherical fluorescence, “zero-dimensional” carbon nanomaterials with a spatial size between 1 nm to 10 nm and have gained widespread attention in recent years. Green CDs are carbon…
View article: Greener synthesis of nanostructured iron oxide for medical and sustainable agro-environmental benefits
Greener synthesis of nanostructured iron oxide for medical and sustainable agro-environmental benefits Open
Nanoscale iron oxide-based nanostructures are among the most apparent metallic nanostructures, having great potential and attracting substantial interest due to their unique superparamagnetic properties. The green production of nanostructu…
View article: Carbon Material Hybrid Construction on an Aptasensor for Monitoring Surgical Tumors
Carbon Material Hybrid Construction on an Aptasensor for Monitoring Surgical Tumors Open
Carcinoembryonic antigen (CEA) is a glycoprotein, one of the common tumor biomarkers, found at low levels in body fluids. Generally, overexpression of CEA is found in various cancers, including ovarian, breast, lung, colorectal, gastric, a…
View article: Microcrystalline Cellulose Generation from Laboratory Cotton Waste and Conventional Characterizations
Microcrystalline Cellulose Generation from Laboratory Cotton Waste and Conventional Characterizations Open
Microcrystalline cellulose (MCC) is a green material that has widespread applications in pharmaceuticals, food, cosmetics, and other industries owing to its biocompatibility, biodegradability, hydrophilicity, and acid-insolubility. Therefo…
View article: Comparative sera proteomics analysis of differentially expressed proteins in oral squamous cell carcinoma
Comparative sera proteomics analysis of differentially expressed proteins in oral squamous cell carcinoma Open
Background Oral squamous cell carcinoma (OSCC) has increased in incidence from 1990 to 2017, especially in South and Southeast Asia. It is often diagnosed at an advanced stage with a poor prognosis. Therefore, early detection of OSCC is es…
View article: Multifunctional Islet Transplantation Hydrogel Encapsulating A20 High-Expressing Islets
Multifunctional Islet Transplantation Hydrogel Encapsulating A20 High-Expressing Islets Open
Xue Bai1,2 *,* Qilin Pei3 *,* Chunyi Pu,1,2 Yi Chen,1,2 Sirong He,1,2 Bin Wang3 1Department of Immunology, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, People&rsquo;s Republic of China; 2Chongqing Key Labo…
View article: Synergistic Effect of Polyalthia longifolia Leaf and Antibiotics against Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA) by Microscopic Technique
Synergistic Effect of Polyalthia longifolia Leaf and Antibiotics against Clinical Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA) by Microscopic Technique Open
Background: Polyalthia longifolia is a popular medicinal plant and has been widely used as a traditional remedy for centuries in curing of various ailments. The purpose of this study was conducted to determine the in situ antimicrobial syn…
View article: Construction of a 13-Gene Signature as a Novel Prognostic Marker for Patients with Clear Cell Renal Cell Carcinoma and the Role of XCR1 in Cell Proliferation
Construction of a 13-Gene Signature as a Novel Prognostic Marker for Patients with Clear Cell Renal Cell Carcinoma and the Role of XCR1 in Cell Proliferation Open
Baoying Yuan,1,* Feifei Li,2,* Youbao Li,3 Yuhan Chen4 1Department of Radiation Oncology, Zhongshan Hospital, Fudan University, Shanghai, People&rsquo;s Republic of China; 2The First Class Ward 2, The First Affiliated Hospital of Jinan…
View article: Coordination of Nanoconjugation with an Antigen/Antibody for Efficient Detection of Gynecological Tumors
Coordination of Nanoconjugation with an Antigen/Antibody for Efficient Detection of Gynecological Tumors Open
Cervical, ovarian, and endometrial cancers are common in the female reproductive system. Cervical cancer starts from the cervix, while ovarian cancer develops when abnormal cells grow in the ovary. Endometrial or uterine cancer starts from…
View article: Coordinated Dispersion and Aggregation of Gold Nanorod in Aptamer-Mediated Gestational Hypertension Analysis
Coordinated Dispersion and Aggregation of Gold Nanorod in Aptamer-Mediated Gestational Hypertension Analysis Open
Gestational hypertension is one of the complicated disorders during pregnancy; it causes the significant risks, such as placental abruption, neonatal deaths, and maternal deaths. Hypertension is also responsible for the metabolic and cardi…
View article: Glucose oxidase complexed gold-graphene nanocomposite on a dielectric surface for glucose detection: a strategy for gestational diabetes mellitus
Glucose oxidase complexed gold-graphene nanocomposite on a dielectric surface for glucose detection: a strategy for gestational diabetes mellitus Open
Yueping Ge,1 Thangavel Lakshmipriya,2 Subash CB Gopinath,2,3 Periasamy Anbu,4 Yeng Chen,5 Firdaus Hariri,6 Lu Li7 1Department of Gynaecology and Obstetrics, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, Zhe…
View article: <p>Glucose oxidase complexed gold-graphene nanocomposite on a dielectric surface for glucose detection: a strategy for gestational diabetes mellitus</p>
Glucose oxidase complexed gold-graphene nanocomposite on a dielectric surface for glucose detection: a strategy for gestational diabetes mellitus Open
This study demonstrated the potential strategy with nanocomposite for diagnosing gestational diabetes mellitus.
View article: The Association between Epstein-Barr virus (EBV) Past Infection with the Risk of Oral Squamous Cell Carcinoma (OSCC)
The Association between Epstein-Barr virus (EBV) Past Infection with the Risk of Oral Squamous Cell Carcinoma (OSCC) Open
This research project assessed the impact of individualistic and interpersonal effects on the
\npatronage of luxury yachts, along with the variables that affect luxury yacht patrons' willingness
\nto pay a price premium (WTPP) in the Fiji …
View article: Squamous Cell Carcinoma Biomarker Sensing on a Strontium Oxide-Modified Interdigitated Electrode Surface for the Diagnosis of Cervical Cancer
Squamous Cell Carcinoma Biomarker Sensing on a Strontium Oxide-Modified Interdigitated Electrode Surface for the Diagnosis of Cervical Cancer Open
Cervical cancer is a life-threatening complication, appearing as the uncontrolled growth of abnormal cells in the lining of the cervix. Every year, increasing numbers of cervical cancer cases are reported worldwide. Different identificatio…
View article: Separation and identification of bioactive peptides from stem of Tinospora cordifolia (Willd.) Miers
Separation and identification of bioactive peptides from stem of Tinospora cordifolia (Willd.) Miers Open
Enzyme hydrolysates (trypsin, papain, pepsin, α-chymotrypsin, and pepsin-pancreatin) of Tinospora cordifolia stem proteins were analyzed for antioxidant efficacy by measuring (1) 1,1-diphenyl-2-picrylhydrazyl (DPPH•) radical scavenging act…
View article: Palladium nanoparticle-decorated reduced graphene oxide sheets synthesized using Ficus carica fruit extract: A catalyst for Suzuki cross-coupling reactions
Palladium nanoparticle-decorated reduced graphene oxide sheets synthesized using Ficus carica fruit extract: A catalyst for Suzuki cross-coupling reactions Open
We present a biogenic method for the synthesis of palladium nanoparticle (PdNP)-modified by reducing graphene oxide sheets (rGO) in a one-pot strategy using Ficus carica fruit juice as the reducing agent. The synthesized material was well …
View article: Amino acid analysis of lipases from oil pollutant isolates:Cunninghamella verticillata and Geotrichum candidum
Amino acid analysis of lipases from oil pollutant isolates:Cunninghamella verticillata and Geotrichum candidum Open
Lipase is an enzyme commonly used in food, dairy, and other industries. Fungal lipases are more commonly used due to their secretion and easier production. Analyses of the amino acid composition of microbial lipases will hasten their poten…