Yeseon Park Moon
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View article: Genome-wide association study of executive function in a multi-ethnic cohort implicates LINC01362: Results from the northern Manhattan study
Genome-wide association study of executive function in a multi-ethnic cohort implicates LINC01362: Results from the northern Manhattan study Open
View article: Influenza-Like Illness is Associated with Increased Short-Term Risk of Cervical Artery Dissection
Influenza-Like Illness is Associated with Increased Short-Term Risk of Cervical Artery Dissection Open
View article: <i>APOE ϵ</i> 4 modifies the relationship between infectious burden and poor cognition
<i>APOE ϵ</i> 4 modifies the relationship between infectious burden and poor cognition Open
Potential effect modification by the APOE ϵ4 allele on the relationship of infection, and particularly viral infection, to cognitive processing speed warrants further investigation.
View article: Creatinine versus cystatin C for renal function-based mortality prediction in an elderly cohort: The Northern Manhattan Study
Creatinine versus cystatin C for renal function-based mortality prediction in an elderly cohort: The Northern Manhattan Study Open
Background: Estimated glomerular filtration rate (eGFR) is routinely utilized as a measure of renal function. While creatinine-based eGFR (eGFRcr) is widely used in clinical practice, the use of cystatin-C to estimate GFR (eGFRcys) has dem…
View article: Interleukin-6 and lipoprotein-associated phospholipase A2 are associated with functional trajectories
Interleukin-6 and lipoprotein-associated phospholipase A2 are associated with functional trajectories Open
In this large population-based study, higher serum inflammatory biomarker levels were associated with disability, even when adjusting for baseline covariates and stroke and MI occurring during follow-up.
View article: Creatinine- versus cystatin C-based renal function assessment in the Northern Manhattan Study
Creatinine- versus cystatin C-based renal function assessment in the Northern Manhattan Study Open
Background Accurate glomerular filtration rate estimation informs drug dosing and risk stratification. Body composition heterogeneity influences creatinine production and the precision of creatinine-based estimated glomerular filtration ra…
View article: Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study
Electrocardiographic left atrial abnormality and silent vascular brain injury: The Northern Manhattan Study Open
Hypothesis We hypothesized that P wave terminal Force in the V1 lead (PTFV1) would be associated with leukoaraiosis and subclinical infarcts, especially cortical infarcts, in a population-based, multi-ethnic cohort. Methods PTFV1 was colle…
View article: Association Between Subclinical Brain Infarcts and Functional Decline Trajectories
Association Between Subclinical Brain Infarcts and Functional Decline Trajectories Open
Objectives To test associations between subclinical brain infarcts (SBIs) and functional decline independently of intervening clinical vascular events and other vascular risk factors. Design Longitudinal follow‐up for a mean 7.3 years. Gen…
View article: Cerebral white matter disease and functional decline in older adults from the Northern Manhattan Study: A longitudinal cohort study
Cerebral white matter disease and functional decline in older adults from the Northern Manhattan Study: A longitudinal cohort study Open
Background Cerebral white matter hyperintensities (WMHs) on MRI are common and associated with vascular and functional outcomes. However, the relationship between WMHs and longitudinal trajectories of functional status is not well characte…
View article: Diet Soda and Sugar-Sweetened Soda Consumption in Relation to Incident Diabetes in the Northern Manhattan Study
Diet Soda and Sugar-Sweetened Soda Consumption in Relation to Incident Diabetes in the Northern Manhattan Study Open
This study supports the importance of sugar-sweetened beverage consumption in the diabetes epidemic. However, the results support previous studies suggesting that switching to artificially sweetened diet beverages may not lower the risk of…
View article: Functional Trajectories, Cognition, and Subclinical Cerebrovascular Disease
Functional Trajectories, Cognition, and Subclinical Cerebrovascular Disease Open
Background and Purpose— Cognition and education influence functional trajectories, but whether associations differ with subclinical brain infarcts (SBI) or white matter hyperintensity volume (WMHV) is unknown. We hypothesized that SBI and …
View article: Regional Subclinical Cerebrovascular Disease Is Associated with Balance in an Elderly Multi-Ethnic Population
Regional Subclinical Cerebrovascular Disease Is Associated with Balance in an Elderly Multi-Ethnic Population Open
Introduction: White matter hyperintensity volume (WMHV) and subclinical brain infarcts (SBI) are associated with impaired mobility, but less is known about the association of WMHV in specific brain regions. We hypothesized th…
View article: Supplementary Material for: Regional Subclinical Cerebrovascular Disease Is Associated with Balance in an Elderly Multi-Ethnic Population
Supplementary Material for: Regional Subclinical Cerebrovascular Disease Is Associated with Balance in an Elderly Multi-Ethnic Population Open
Introduction: White matter hyperintensity volume (WMHV) and subclinical brain infarcts (SBI) are associated with impaired mobility, but less is known about the association of WMHV in specific brain regions. We hypothesized th…
View article: Brain Arterial Diameters and Cognitive Performance: The Northern Manhattan Study
Brain Arterial Diameters and Cognitive Performance: The Northern Manhattan Study Open
O bjectives: To test the hypothesis that brain arterial diameters are associated with cognitive performance, particularly in arteries supplying domain-specific territories. Methods: Stroke-free participants in the Northern Manhattan Study …
View article: Mentored peer review of standardized manuscripts as a teaching tool for residents: a pilot randomized controlled multi-center study
Mentored peer review of standardized manuscripts as a teaching tool for residents: a pilot randomized controlled multi-center study Open
We used mentored peer review of standardized manuscripts to teach biostatistics and research methodology and introduce the peer review process to residents. Though knowledge level did not change, mentored residents had enhanced perception …
View article: Quality of life independently predicts long-term mortality but not vascular events: the Northern Manhattan Study
Quality of life independently predicts long-term mortality but not vascular events: the Northern Manhattan Study Open
View article: Association Between Serum Tumor Necrosis Factor Receptor 1 and Trajectories of Functional Status
Association Between Serum Tumor Necrosis Factor Receptor 1 and Trajectories of Functional Status Open
We hypothesized that tumor necrosis factor receptor 1 (TNFR1) levels are associated with long-term trajectories of functional status independently of vascular risk factors and the occurrence of stroke and myocardial infarction (MI) during …
View article: Procalcitonin and Midregional Proatrial Natriuretic Peptide as Biomarkers of Subclinical Cerebrovascular Damage
Procalcitonin and Midregional Proatrial Natriuretic Peptide as Biomarkers of Subclinical Cerebrovascular Damage Open
Background and Purpose— Chronic infections and cardiac dysfunction are risk factors for stroke. We hypothesized that blood biomarkers of infection (procalcitonin) and cardiac dysfunction (midregional proatrial natriuretic peptide [MR-proAN…
View article: Supplementary Material for: Physical Inactivity Predicts Slow Gait Speed in an Elderly Multi-Ethnic Cohort Study: The Northern Manhattan Study
Supplementary Material for: Physical Inactivity Predicts Slow Gait Speed in an Elderly Multi-Ethnic Cohort Study: The Northern Manhattan Study Open
Introduction: Gait speed is associated with multiple adverse outcomes of aging. We hypothesized that physical inactivity would be prospectively inversely associated with gait speed independently of white matter hyperintensity…
View article: Physical Inactivity Predicts Slow Gait Speed in an Elderly Multi-Ethnic Cohort Study: The Northern Manhattan Study
Physical Inactivity Predicts Slow Gait Speed in an Elderly Multi-Ethnic Cohort Study: The Northern Manhattan Study Open
Introduction: Gait speed is associated with multiple adverse outcomes of aging. We hypothesized that physical inactivity would be prospectively inversely associated with gait speed independently of white matter hyperintensity…
View article: Supplementary Material for: Physical Inactivity Predicts Slow Gait Speed in an Elderly Multi-Ethnic Cohort Study: The Northern Manhattan Study
Supplementary Material for: Physical Inactivity Predicts Slow Gait Speed in an Elderly Multi-Ethnic Cohort Study: The Northern Manhattan Study Open
Introduction: Gait speed is associated with multiple adverse outcomes of aging. We hypothesized that physical inactivity would be prospectively inversely associated with gait speed independently of white matter hyperintensity…
View article: Physical inactivity is a strong risk factor for stroke in the oldest old: Findings from a multi-ethnic population (the Northern Manhattan Study)
Physical inactivity is a strong risk factor for stroke in the oldest old: Findings from a multi-ethnic population (the Northern Manhattan Study) Open
Background The fastest growing segment of the population is those age ≥80 who have the highest stroke incidence. Risk factor management is complicated by polypharmacy-related adverse events. Aims To characterize the impact of physical inac…
View article: Leisure-Time Physical Activity and Cardiovascular Mortality in an Elderly Population in Northern Manhattan: A Prospective Cohort Study
Leisure-Time Physical Activity and Cardiovascular Mortality in an Elderly Population in Northern Manhattan: A Prospective Cohort Study Open
View article: C-reactive protein is associated with disability independently of vascular events: the Northern Manhattan Study
C-reactive protein is associated with disability independently of vascular events: the Northern Manhattan Study Open
In this large population-based study, higher serum CRP levels were associated with higher baseline disability, even when adjusting for baseline covariates and stroke and MI occurring during follow-up. Systemic inflammation may contribute t…
View article: Procalcitonin and Midregional Proatrial Natriuretic Peptide as Markers of Ischemic Stroke
Procalcitonin and Midregional Proatrial Natriuretic Peptide as Markers of Ischemic Stroke Open
Background and Purpose— Chronic infections and neuroendocrine dysfunction may be risk factors for ischemic stroke (IS). We hypothesized that selected blood biomarkers of infection (procalcitonin [PCT]), hypothalamic–pituitary–axis function…
View article: Leisure-time physical activity associates with cognitive decline
Leisure-time physical activity associates with cognitive decline Open
A low level of LTPA is independently associated with greater decline in cognitive performance over time across domains.
View article: Racial–ethnic disparities in the association between risk factors and diabetes: The Northern Manhattan Study
Racial–ethnic disparities in the association between risk factors and diabetes: The Northern Manhattan Study Open
View article: Electrocardiographic Left Atrial Abnormality and Risk of Stroke
Electrocardiographic Left Atrial Abnormality and Risk of Stroke Open
Background and Purpose— Electrocardiographic left atrial abnormality has been associated with stroke independently of atrial fibrillation (AF), suggesting that atrial thromboembolism may occur in the absence of AF. If true, we would expect…
View article: Left Atrial Enlargement and Stroke Recurrence
Left Atrial Enlargement and Stroke Recurrence Open
Background and Purpose— Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related t…