Yeshu Wang
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View article: MiR-124-3p mediates gastric cancer cell ferroptosis induced by an anti-cancer drug polyphyllin I
MiR-124-3p mediates gastric cancer cell ferroptosis induced by an anti-cancer drug polyphyllin I Open
Background: Ferroptosis is an emerging type of regulated cell death and associated with antitumoral therapy, while some microRNAs have been shown to regulate the tumorigenesis and cancer progression. Meanwhile, polyphyllin I (PPI) has exhi…
View article: Corrigendum: Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis
Corrigendum: Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis Open
[This corrects the article DOI: 10.3389/fphar.2023.1145407.].
View article: Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis
Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis Open
Background: Ferroptosis is a new form of regulated cell death characterized by the accumulation of iron-dependent lipid peroxides and membrane damages. Recent studies have identified an important role for cancer cell ferroptosis in antitum…
View article: Chinese medicine<i>Ginseng</i>and<i>Astragalus</i>granules ameliorate autoimmune diabetes by upregulating both CD4+FoxP3+ and CD8+CD122+PD1+ regulatory T cells
Chinese medicine<i>Ginseng</i>and<i>Astragalus</i>granules ameliorate autoimmune diabetes by upregulating both CD4+FoxP3+ and CD8+CD122+PD1+ regulatory T cells Open
Type 1 diabetes mellitus (T1DM) is an autoimmune disease mainly mediated by effector T cells that are activated by autoantigen, thereby resulting in the destruction of pancreatic islets and deficiency of insulin. Cyclosporine is widely use…
View article: Suppression of allograft rejection by CD8+CD122+PD-1+ Tregs is dictated by their Fas ligand-initiated killing of effector T cells<i>versus</i>Fas-mediated own apoptosis
Suppression of allograft rejection by CD8+CD122+PD-1+ Tregs is dictated by their Fas ligand-initiated killing of effector T cells<i>versus</i>Fas-mediated own apoptosis Open
Mounting evidence has shown that naturally occurring CD8+CD122+ T cells are regulatory T cells (Tregs) that suppress both autoimmunity and alloimmunity. We have previously shown that CD8+CD122+PD-1+ Tregs not only suppress allograft reject…