Yeuni Yu
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Author Swipe
View article: The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models
The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models Open
Hepatocellular carcinoma (HCC) requires novel therapeutic targets, and oncofetal genes offer a promising avenue. Although the adaptor protein AP2M1 is a known prognostic factor in HCC, its functional role in promoting cancer stemness remai…
View article: Identification of circulating miRNA alterations in diabetes patients excluding periodontitis effects: insights into target gene downregulation in diabetic complications
Identification of circulating miRNA alterations in diabetes patients excluding periodontitis effects: insights into target gene downregulation in diabetic complications Open
This study suggests that circulating exosomal miRNAs, independent of periodontitis, may function as systemic regulators in diabetes. Unlike previous studies, which did not distinguish co-morbid periodontitis, we specifically defined PD-ind…
View article: AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients
AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients Open
Acute myeloid leukemia (AML) is a complex hematological malignancy characterized by chemotherapy resistance, leading to poor patient outcomes. This study investigates the role of adaptor protein complex 2 subunit mu 1 (AP2M1) in hematopoie…
View article: The radioprotective role of human Alistipes onderdonkii identified by multi-omic analysis in patients with prostate cancer
The radioprotective role of human Alistipes onderdonkii identified by multi-omic analysis in patients with prostate cancer Open
This finding establishes the foundation for developing microbiome-based therapeutics for the gut health of cancer patients undergoing radiotherapy.
View article: Uncovering NK cell sabotage in gut diseases via single cell transcriptomics
Uncovering NK cell sabotage in gut diseases via single cell transcriptomics Open
The identification of immune environments and cellular interactions in the colon microenvironment is essential for understanding the mechanisms of chronic inflammatory disease. Despite occurring in the same organ, there is a significant ga…
View article: Correction: Biofilm microbiome in extracorporeal membrane oxygenator catheters
Correction: Biofilm microbiome in extracorporeal membrane oxygenator catheters Open
[This corrects the article DOI: 10.1371/journal.pone.0257449.].
View article: Integrative Genomic and Transcriptomic Analysis in Acute Interstitial Pneumonia
Integrative Genomic and Transcriptomic Analysis in Acute Interstitial Pneumonia Open
Acute Interstitial Pneumonia (AIP) represents a severe form of diffuse lung injury within the idiopathic interstitial pneumonia spectrum. Given the limited understanding of its molecular basis, this study aims to elucidate AIP's genomic an…
View article: Unique Changes in the Lung Microbiome following the Development of Chronic Lung Allograft Dysfunction
Unique Changes in the Lung Microbiome following the Development of Chronic Lung Allograft Dysfunction Open
The importance of lung microbiome changes in developing chronic lung allograft dysfunction (CLAD) after lung transplantation is poorly understood. The lung microbiome–immune interaction may be critical in developing CLAD. In this context, …
View article: Highly Aligned Ternary Nanofiber Matrices Loaded with MXene Expedite Regeneration of Volumetric Muscle Loss
Highly Aligned Ternary Nanofiber Matrices Loaded with MXene Expedite Regeneration of Volumetric Muscle Loss Open
Current therapeutic approaches for volumetric muscle loss (VML) face challenges due to limited graft availability and insufficient bioactivities. To overcome these limitations, tissue-engineered scaffolds have emerged as a promising altern…
View article: Differential microbiota network according to colorectal cancer lymph node metastasis stages
Differential microbiota network according to colorectal cancer lymph node metastasis stages Open
Purpose: Colorectal cancer (CRC) is a common malignancy worldwide and the second leading cause of cancer-related deaths.In addition, lymph node metastasis in CRC is considered an important prognostic factor for predicting disease recurrenc…
View article: Comparative Analysis of Primers Used for 16S rRNA Gene Sequencing in Oral Microbiome Studies
Comparative Analysis of Primers Used for 16S rRNA Gene Sequencing in Oral Microbiome Studies Open
Recent advances in genomic technologies have enabled more in-depth study of the oral microbiome. In this study, we compared the amplicons generated by primers targeting different sites of the 16S rRNA gene found in the Human Oral Microbiom…
View article: Tumor Microenvironment Can Predict Chemotherapy Response of Patients with Triple-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy
Tumor Microenvironment Can Predict Chemotherapy Response of Patients with Triple-Negative Breast Cancer Receiving Neoadjuvant Chemotherapy Open
Purpose Triple-negative breast cancer (TNBC) is a breast cancer subtype that has poor prognosis and exhibits a unique tumor microenvironment. Analysis of the tumor microbiome has indicated a relationship between the tumor microenvironment …
View article: Single-cell analysis of platelets from patients with periodontitis and diabetes
Single-cell analysis of platelets from patients with periodontitis and diabetes Open
These results suggest that periodontitis contributes to establishment of blood coagulation via platelet dysregulation, whereas the comorbidities of patients with periodontitis and DM impair the components of platelets, thus preventing norm…
View article: The oral microbiome of implant-abutment screw holes compared with the peri-implant sulcus and natural supragingival plaque in healthy individuals
The oral microbiome of implant-abutment screw holes compared with the peri-implant sulcus and natural supragingival plaque in healthy individuals Open
The bacterial composition of the biofilm collected from the implant-abutment screw hole exhibited significant differences compared to the supra-structure of the implant. Therefore, long-term monitoring and management of not only the peri-i…
View article: Differential microbiota network in gingival tissues between periodontitis and periodontitis with diabetes
Differential microbiota network in gingival tissues between periodontitis and periodontitis with diabetes Open
Periodontitis and diabetes mellitus (DM) have a bidirectional relationship. Periodontitis is initiated by dysbiosis of oral microorganisms, and in particular, the characteristics of the microorganisms that have penetrated the tissue are di…
View article: Microbial profiling of peri-implantitis compared to the periodontal microbiota in health and disease using 16S rRNA sequencing
Microbial profiling of peri-implantitis compared to the periodontal microbiota in health and disease using 16S rRNA sequencing Open
The composition of the microbiota was considerably different in PI subjects compared to PH and PT subjects, and these results could shed light on the mechanisms involved in the development of PI.
View article: Identification of Shared Genes and Pathways in Periodontitis and Type 2 Diabetes by Bioinformatics Analysis
Identification of Shared Genes and Pathways in Periodontitis and Type 2 Diabetes by Bioinformatics Analysis Open
Introduction It is well known that the presence of diabetes significantly affects the progression of periodontitis and that periodontitis has negative effects on diabetes and diabetes-related complications. Although this two-way relationsh…
View article: Microbial And Molecular Differences According To The Location of Head And Neck Cancers
Microbial And Molecular Differences According To The Location of Head And Neck Cancers Open
Background : Microbiome has been shown to substantially contribute to some cancers. However, the diagnostic implications of microbiome in head and neck squamous cell carcinoma (HNSCC) remain unknown. Methods : we report for the first time,…
View article: Additional file 2 of Microbial and molecular differences according to the location of head and neck cancers
Additional file 2 of Microbial and molecular differences according to the location of head and neck cancers Open
Additional file 2: Table S1. The GO analysis results, hub genes, and tumour locations of included patients.
View article: Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and cancer risk: an updated meta-analysis of observational studies
Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and cancer risk: an updated meta-analysis of observational studies Open
Introduction: Debate on the association between the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) and the risk of developing cancer has been ongoing for decades. This study aimed to genera…
View article: DeepCIA: a novel deep-learning model for cancer type identification using class activation map via transcription factor expression.
DeepCIA: a novel deep-learning model for cancer type identification using class activation map via transcription factor expression. Open
Deep learning methods are powerful analytical tools for large-scale data analysis. Here, we introduce DeepCIA as a novel diagnostic deep-learning model for cancer type identification using a class activation map via transcription factor ex…
View article: Oral Microbiota Change in Intubated Patients under Mechanical Ventilation
Oral Microbiota Change in Intubated Patients under Mechanical Ventilation Open
One of the complications that may develop in intubated patients under mechanical ventilator is ventilator‐associated pneumonia (VAP). In most cases, VAP appears to result from aspiration of the oropharyngeal microflora or colonizing pathog…
View article: The unique changes of lung microbiome in chronic lung allograft dysfunction
The unique changes of lung microbiome in chronic lung allograft dysfunction Open
Background: Both unique bacterial populations and longitudinal changes in the lung microbiome may play a critical role in the development of chronic lung allograft dysfunction (CLAD).Methods: We evaluated the difference in lung microbiome …
View article: SOCS3 is Related to Cell Proliferation in Neuronal Tissue: An Integrated Analysis of Bioinformatics and Experiments
SOCS3 is Related to Cell Proliferation in Neuronal Tissue: An Integrated Analysis of Bioinformatics and Experiments Open
Glioma is the most common primary malignant tumor that occurs in the central nervous system. Gliomas are subdivided according to a combination of microscopic morphological, molecular, and genetic factors. Glioblastoma (GBM) is the most agg…
View article: Microbial and Molecular Differences According To The Location of Head and Neck Cancers
Microbial and Molecular Differences According To The Location of Head and Neck Cancers Open
Background Microbiome has been shown to substantially contribute to some cancers. However, the diagnostic implications of microbiome in head and neck squamous cell carcinoma (HNSCC) remain unknown. Here, we report for the first time, the m…