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View article: Isovitexin and Chlorogenic Acid from <i>Juncus decipiens</i> (Buchenau) Nakai Target Melanogenesis and Enhance Photoprotection
Isovitexin and Chlorogenic Acid from <i>Juncus decipiens</i> (Buchenau) Nakai Target Melanogenesis and Enhance Photoprotection Open
Background: Juncus decipiens , a medicinal plant with a long history of traditional use, has been reported to possess diverse biological activities; however, its potential in regulating melanogenesis and protecting against ultraviolet (UV)…
View article: Promising Natural Polyphenols from Olive (Olea europaea) Leaves and Seeds: Dual Benefits in the Prevention of Ultraviolet B-induced Fibroblast Skin Damage and Anti Skin Hyperpigmentation
Promising Natural Polyphenols from Olive (Olea europaea) Leaves and Seeds: Dual Benefits in the Prevention of Ultraviolet B-induced Fibroblast Skin Damage and Anti Skin Hyperpigmentation Open
View article: Evaluation of hesperidin as a potential larvicide against Culex pipiens with computational prediction of its mode of action via molecular docking
Evaluation of hesperidin as a potential larvicide against Culex pipiens with computational prediction of its mode of action via molecular docking Open
View article: Quassinoids from Malaysian <i>Eurycoma longifolia</i> significantly increased the expression of the melatonin biosynthesis-related enzyme gene (AANAT)
Quassinoids from Malaysian <i>Eurycoma longifolia</i> significantly increased the expression of the melatonin biosynthesis-related enzyme gene (AANAT) Open
Three representative C 20 -quassinoids (1–3) isolated from Eurycoma longifolia roots significantly upregulated AANAT, a key gene in melatonin biosynthesis, compared to the control.
View article: Exploring sesquiterpene lactones: structural diversity and antiviral therapeutic insights
Exploring sesquiterpene lactones: structural diversity and antiviral therapeutic insights Open
Sesquiterpene lactones (SLs) are a structurally diverse group of secondary metabolites primarily produced by plants, particularly within the Asteraceae family.
View article: Triterpene saponins from the halophyte <i>Anabasis setifera</i> exhibit anti-SARS-CoV-2 properties
Triterpene saponins from the halophyte <i>Anabasis setifera</i> exhibit anti-SARS-CoV-2 properties Open
Halophytes are well-known as a rich source of health-promoting phytochemicals.
View article: Special Issue—“Natural Products That Might Change Society”
Special Issue—“Natural Products That Might Change Society” Open
This Special Issue of Molecules gathers eight research papers and two review articles covering the isolation, identification, and biological activity of selected natural products, with the aim of discovering potential candidates that could…
View article: Unveiling the Antiviral Efficacy of Forskolin: A Multifaceted In Vitro and In Silico Approach
Unveiling the Antiviral Efficacy of Forskolin: A Multifaceted In Vitro and In Silico Approach Open
Coleus forskohlii (Willd.) Briq. is a medicinal herb of the Lamiaceae family. It is native to India and widely present in the tropical and sub-tropical regions of Egypt, China, Ethiopia, and Pakistan. The roots of C. forskohlii are edible,…
View article: Bio-Modulation of Post-Harvested Potato: LC-ESI-MS, GC-MS Analysis, Antioxidant and -amylase Activity of Treated Potato Peels
Bio-Modulation of Post-Harvested Potato: LC-ESI-MS, GC-MS Analysis, Antioxidant and -amylase Activity of Treated Potato Peels Open
Potato peel may play a mixed blessing role via providing useful and economic compounds, in contrast, it contains very toxic glycoalkaloids.However, massive amounts of potato peel waste are generated from industrial and personal uses.The ev…
View article: Chemical compositions and antimicrobial activities of three lemon odor essential oils of <i>Cupressus macrocarpa</i> , <i>Cymbopogon citratus.</i> and <i>Citrus limon</i>
Chemical compositions and antimicrobial activities of three lemon odor essential oils of <i>Cupressus macrocarpa</i> , <i>Cymbopogon citratus.</i> and <i>Citrus limon</i> Open
Infectious diseases caused by bacteria, fungi and viruses are globally of major concern. Plant essential oils produced by various differentiated structures possess varied properties as significant antiseptic, antibacterial, antifungal, ant…
View article: Effect of Eriobotrya japonica Leaf Supplements on Allergic Rhinitis Symptoms and Skin Conditions in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study
Effect of Eriobotrya japonica Leaf Supplements on Allergic Rhinitis Symptoms and Skin Conditions in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Study Open
Eriobotrya japonica (E. japonica) leaves have been used as an herbal traditional medicine in China and Japan owing to their anti-inflammatory and protective effects against skin conditions and allergy symptoms. These beneficial effects are…
View article: Psidium guajava L.: Chemical composition and protective effects of a leaf extract against ethanol-induced cardiotoxicity
Psidium guajava L.: Chemical composition and protective effects of a leaf extract against ethanol-induced cardiotoxicity Open
It has been previously reported that a leaf extract of Psidium guajava L. (GV.E) can impart numerous health benefits that were attributed to its antioxidant and anti-inflammatory effects. Ethanol (EtOH, alcohol) misuse is a global health b…
View article: Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound
Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound Open
Hericium erinaceus, a mushroom species commonly known as Yamabushitake in Japan, is known to have a stimulatory effect on neurotrophic factors, such as brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF). Hericenone C, a…
View article: Cytotoxicity effect of prenylated flavonoids from Stingless Bee (Wallacetrigona insica) propolis in some cancer cell lines
Cytotoxicity effect of prenylated flavonoids from Stingless Bee (Wallacetrigona insica) propolis in some cancer cell lines Open
Propolis is a bee product traditionally used for therapy in several diseases. The therapeutic activities of propolis, such as antioxidant, antifungal, antibacterial, and anti-inflammatory, are commonly known. Propolis from the stingless be…
View article: Editorial: Natural products as potential therapies for non-alcoholic fatty liver disease
Editorial: Natural products as potential therapies for non-alcoholic fatty liver disease Open
EDITORIAL article Front. Pharmacol., 11 April 2023Sec. Ethnopharmacology Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1180263
View article: Melanin Synthesis Inhibition Activity of Compounds Isolated from Bamboo Shoot Skin (Phyllostachys pubescens)
Melanin Synthesis Inhibition Activity of Compounds Isolated from Bamboo Shoot Skin (Phyllostachys pubescens) Open
This study targets the evaluation of melanin synthesis inhibition activity of the bamboo shoot skin as agro-waste. The total methanolic extract of bamboo peel extract was evaluated for its skin protective effects via measuring its melanin …
View article: New Butyroside D from Argan Press Cake Possess Anti-Melanogenesis Effect via MITF Downregulation in B16F10 and HEM Cells
New Butyroside D from Argan Press Cake Possess Anti-Melanogenesis Effect via MITF Downregulation in B16F10 and HEM Cells Open
Hyperpigmentation is a skin condition where patches of skin become darker in color due to excess melanin production upon UV exposure leading to melasma, which are lentigines or post inflammatory hyperpigmentation that psychologically affec…
View article: Metformin: A Small Molecule with Multi-Targets and Diverse Therapeutic Applications
Metformin: A Small Molecule with Multi-Targets and Diverse Therapeutic Applications Open
Metformin is one of the most prescribed agents in the treatment of type 2 diabetes. Its history goes back to the use of goat’s rue (Galega officinalis Linn., Fabaceae). G. officinalis is rich in galegine, a guanidine derivative with a bloo…
View article: Phytochemical Analysis, Anti-inflammatory, and Anticancer Activities of the Halophyte Herb <i>Bassia indica</i>
Phytochemical Analysis, Anti-inflammatory, and Anticancer Activities of the Halophyte Herb <i>Bassia indica</i> Open
Bassia indica (Wight) A.J. Scott, family Amaranthaceae, is a halophyte herb growing in extreme environments and hence deemed as a potential economic source of bioactive chemicals with functional properties. In our study, 25 compounds were …
View article: Screening of Selected Stingless Bee Honey Varieties for ACE2-Spike Protein-Binding Inhibition Activity: A Potential Preventive Medicine Against SARS-Cov-2 Infection
Screening of Selected Stingless Bee Honey Varieties for ACE2-Spike Protein-Binding Inhibition Activity: A Potential Preventive Medicine Against SARS-Cov-2 Infection Open
The broader objective of this study is to identify natural materials that might inhibit the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We have focused on stingless bee honey, which has a unique taste that is bo…
View article: Potential of Hibiscus sabdariffa L. and Hibiscus Acid to Reverse Skin Aging
Potential of Hibiscus sabdariffa L. and Hibiscus Acid to Reverse Skin Aging Open
Hibiscus sabdariffa L. (HS) has a long history of edible and medicinal uses. In this study, the biological activities of the extracts, chromatographic fractions, and hibiscus acid obtained from HS were evaluated for their potential bioacti…
View article: Genus Lactuca (Asteraceae): A Comprehensive Review
Genus Lactuca (Asteraceae): A Comprehensive Review Open
Genus Lactuca L. belongs to one of the major families of flowering plants, Asteraceae.It includes about 150 species, distributed in warm and temperate areas, commonly in the Northern Hemisphere.Since ancient times, numerous Lactuca L. spec…
View article: Undescribed glucosylceramide, flavonol triglycoside, and oleanane saponin from the halophyte Agathophora alopecuroides: Promising candidates for stimulating ceramide synthesis
Undescribed glucosylceramide, flavonol triglycoside, and oleanane saponin from the halophyte Agathophora alopecuroides: Promising candidates for stimulating ceramide synthesis Open
View article: Validation of the potential anti-inflammatory activity of Plumbago auriculata Lam
Validation of the potential anti-inflammatory activity of Plumbago auriculata Lam Open
This study targets scientific validation of the claimed anti-inflammatory activity of Plumbago auriculata Lam. The total methanolic extract of the aerial parts of P. auriculata Lam. and its different fractions were evaluated for their anti…
View article: Anti-diabetic activities of phenolic compounds of <i>Alternaria</i> sp., an endophyte isolated from the leaves of desert plants growing in Egypt
Anti-diabetic activities of phenolic compounds of <i>Alternaria</i> sp., an endophyte isolated from the leaves of desert plants growing in Egypt Open
Six phenolic compounds were isolated from the solid rice culture media of Alternaria sp., an endophyte isolated from the leaves of three desert plants, Lycium schweinfurthii Dammer (Solanaceae), Pancratium maritimum L. (Amaryllidaceae) and…
View article: Possible neuroprotective effects of amide alkaloids from <i>Bassia indica</i> and <i>Agathophora alopecuroides</i>: <i>in vitro</i> and <i>in silico</i> investigations
Possible neuroprotective effects of amide alkaloids from <i>Bassia indica</i> and <i>Agathophora alopecuroides</i>: <i>in vitro</i> and <i>in silico</i> investigations Open
Bassia indica and Agathophora alopecuroides could be utilized as potential sources of candidate compounds for the management of Alzheimer disease.
View article: Antioxidant, Anti Inflammatory and Anti Acne Activities of Stingless Bee (Tetragonula Biroi) Propolis
Antioxidant, Anti Inflammatory and Anti Acne Activities of Stingless Bee (Tetragonula Biroi) Propolis Open
View article: Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features
Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features Open
Chromone glycosides comprise an important group of secondary metabolites. They are widely distributed in plants and, to a lesser extent, in fungi and bacteria. Significant biological activities, including antiviral, anti-inflammatory, anti…
View article: Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines
Cytotoxicity effect of honey, bee pollen, and propolis from seven stingless bees in some cancer cell lines Open
Our effort to find new material for anti cancer from natural resources leads us to focus on stingless bee products such as honey, bee pollen, and propolis. The products were from seven stingless bees named Homotrigona fimbriata, Heterot…
View article: Analysis of Antioxidant and Antiallergic Active Components Extracted From the Edible Insect <i>Oxya yezoensis</i>
Analysis of Antioxidant and Antiallergic Active Components Extracted From the Edible Insect <i>Oxya yezoensis</i> Open
In recent years, entomophagy has attracted increased attention, as it was recommended as a potential source of food by the Food and Agriculture Organization of the United Nations. In Japan, Oxya yezoensisis one of the most widely eaten ins…