Yi‐Fen Chen
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View article: Exploring the Intention to Share Personal Exercise Information on Social Networking Sites via Sports Apps Using a Modification of the Theory of Reasoned Action
Exploring the Intention to Share Personal Exercise Information on Social Networking Sites via Sports Apps Using a Modification of the Theory of Reasoned Action Open
The global surge in health awareness and the widespread adoption of fitness applications (apps) on smartphones have reshaped how individuals approach health and leisure activities. This study employs a modified model of the Theory of Reaso…
View article: Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways
Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways Open
Disused muscle atrophy (DMA) is characterized by skeletal muscle loss and functional decline due to prolonged inactivity. Though evidence remains limited, recent studies suggest that ferroptosis, an iron-dependent, lipid peroxidation-drive…
View article: Exercise Attenuates Skeletal Muscle Atrophy in Senescent SAMP8 Mice: Metabolic Insights from NMR-Based Metabolomics
Exercise Attenuates Skeletal Muscle Atrophy in Senescent SAMP8 Mice: Metabolic Insights from NMR-Based Metabolomics Open
Age-related skeletal muscle atrophy is a major health concern in the elderly, contributing to reduced mobility, increased risk of falls, and metabolic dysfunction. The senescence-accelerated prone 8 (SAMP8) mouse model, known for its rapid…
View article: Pharmacokinetics and Safety Profile of <scp>SNS812</scp>, a First in Human Fully Modified <scp>siRNA</scp> Targeting Wide‐Spectrum <scp>SARS</scp>‐<scp>CoV</scp>‐2, in Healthy Subjects
Pharmacokinetics and Safety Profile of <span>SNS812</span>, a First in Human Fully Modified <span>siRNA</span> Targeting Wide‐Spectrum <span>SARS</span>‐<span>CoV</span>‐2, in Healthy Subjects Open
Severe acute respiratory syndrome caused by the coronavirus (SARS‐CoV‐2) in the COVID‐19 pandemic has highlighted the need for effective treatments, as rapid viral mutations complicate therapeutic development. SNS812, a fully modified inha…
View article: Effects of Facebook Fan Pages on Consumer Brand Loyalty and Purchase Intention
Effects of Facebook Fan Pages on Consumer Brand Loyalty and Purchase Intention Open
As companies began to leverage Facebook, a series of marketing battles ensued. Facebook’s growing popularity has made social media an essential tool in internet marketing. This study examines how interactive features of Facebook fan pages …
View article: Barriers and facilitators to high-volume evidence-based innovation and implementation in a large, community-based learning health system
Barriers and facilitators to high-volume evidence-based innovation and implementation in a large, community-based learning health system Open
Background Broad-scale, rapid health care change is critically needed to improve value-based, effective health care. Health care providers and systems need to address common barriers and facilitators across the evidence to implementation p…
View article: Barriers and Facilitators to High-Volume Evidence-Based Innovation and Implementation in a Large, Community-Based Learning Health System
Barriers and Facilitators to High-Volume Evidence-Based Innovation and Implementation in a Large, Community-Based Learning Health System Open
Background Broad-scale, rapid health care change is critically needed to improve value-based, effective health care. Health care providers and systems need to address common barriers and facilitators across the evidence to implementation p…
View article: Do Initiator Characteristics Impact Member Decision: A Study of Online Group Buying in Taiwan
Do Initiator Characteristics Impact Member Decision: A Study of Online Group Buying in Taiwan Open
In recent years, online group buying has rapidly become popular and has become an important part of Internet users’ social life and shopping activities. The current study sought to examine the relationships between members and initiators i…
View article: Do Initiator Characteristics Impact Member Decision: A Study of Online Group Buying in Taiwan
Do Initiator Characteristics Impact Member Decision: A Study of Online Group Buying in Taiwan Open
In recent years, online group buying has rapidly become popular and has become an important part of Internet users’ social life and shopping activities. The current study sought to examine the relationships between members and initiators i…
View article: Effects of Facebook Fan Pages on Consumer Brand Loyalty and Purchase Intention
Effects of Facebook Fan Pages on Consumer Brand Loyalty and Purchase Intention Open
Business organisations use Facebook fan pages to market their brand by tapping into virtual communities to attract customers. This study investigates whether consumers joining Facebook fan pages identify with and trust brand communities by…
View article: Independent Travelers’ Knowledge-Sharing Willingness in Travel Social Networking Sites
Independent Travelers’ Knowledge-Sharing Willingness in Travel Social Networking Sites Open
Purpose With the rise of the Internet and the emergence of the global social community, independent travelers are increasingly engaging in real-time interaction and knowledge sharing through travel social networking sites. Existing studies…
View article: The Effect of Price Discrimination on Fairness Perception and Online Hotel Reservation Intention
The Effect of Price Discrimination on Fairness Perception and Online Hotel Reservation Intention Open
In light of the development of online travel agencies (OTAs), the rules of the entire tourism industry have changed. Due to the ease of finding information and comparing products, consumers can choose a hotel not only by room type, but als…
View article: Data from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity
Data from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity Open
miR-211 expression in human oral squamous cell carcinoma (OSCC) has been implicated in poor patient survival. To investigate the oncogenic roles of miR-211, we generated K14-EGFP-miR-211 transgenic mice tagged with GFP. Induction of oral c…
View article: Data from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity
Data from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity Open
miR-211 expression in human oral squamous cell carcinoma (OSCC) has been implicated in poor patient survival. To investigate the oncogenic roles of miR-211, we generated K14-EGFP-miR-211 transgenic mice tagged with GFP. Induction of oral c…
View article: Supplementary Materials and Methods, Supplementary Tables 1 through 10, and Supplementary Figures 1 through 20 from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity
Supplementary Materials and Methods, Supplementary Tables 1 through 10, and Supplementary Figures 1 through 20 from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity Open
Supplementary Materials and Methods. Table S1. Cell cultivation conditions. Table S2. siRNAs used in the present study. Table S3. TaqMan assay probes used in the present study. Table S4. Primers used in the present study. Table S5. shRNA c…
View article: Supplementary Materials and Methods, Supplementary Tables 1 through 10, and Supplementary Figures 1 through 20 from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity
Supplementary Materials and Methods, Supplementary Tables 1 through 10, and Supplementary Figures 1 through 20 from MicroRNA-211 Enhances the Oncogenicity of Carcinogen-Induced Oral Carcinoma by Repressing TCF12 and Increasing Antioxidant Activity Open
Supplementary Materials and Methods. Table S1. Cell cultivation conditions. Table S2. siRNAs used in the present study. Table S3. TaqMan assay probes used in the present study. Table S4. Primers used in the present study. Table S5. shRNA c…
View article: A siRNA targets and inhibits a broad range of SARS‐CoV‐2 infections including Delta variant
A siRNA targets and inhibits a broad range of SARS‐CoV‐2 infections including Delta variant Open
The emergence of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) variants has altered the trajectory of the COVID‐19 pandemic and raised some uncertainty on the long‐term efficiency of vaccine strategy. The development of new …
View article: Impact of Premium and Price Cuts on Consumer Purchase Intention
Impact of Premium and Price Cuts on Consumer Purchase Intention Open
This study aims to compare the price cut and premium promotion with study moderators are discount depth size, product type, premium characteristics, and country effect (Indonesia and Taiwan). The experiment was designed as: (promotional di…
View article: Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors
Mitochondrial genome and its regulator TFAM modulates head and neck tumourigenesis through intracellular metabolic reprogramming and activation of oncogenic effectors Open
Mitochondrial transcriptional factor A (TFAM) acts as a key regulatory to control mitochondrial DNA (mtDNA); the impact of TFAM and mtDNA in modulating carcinogenesis is controversial. Current study aims to define TFAM mediated regulations…
View article: DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation
DDX3 modulates the tumor microenvironment via its role in endoplasmic reticulum-associated translation Open
View article: Mitochondrial Genome Regulator TFAM Modulates Head and Neck Tumorigenesis Through Activation of Intracellular Metabolic Reprogramming and Oncogenic Effectors
Mitochondrial Genome Regulator TFAM Modulates Head and Neck Tumorigenesis Through Activation of Intracellular Metabolic Reprogramming and Oncogenic Effectors Open
Background: Mitochondrial defect is often observed in cancers while, in comparison with other metabolic cues, mitochondria mediated regulations in controlling tumorigenesis are less emphasized. Mitochondrial transcriptional factor A (TFAM)…
View article: Abstract 4635: Newly established mouse oral carcinoma cell lines and their syngeneic tumorigenesis models
Abstract 4635: Newly established mouse oral carcinoma cell lines and their syngeneic tumorigenesis models Open
Oral squamous cell carcinoma (OSCC) is one of the most prevalent malignancies worldwide. Despite the advances in diagnosis and treatment, the survival of OSCC remains to be improved. miR-211 is an oncogenic microRNA frequently disrupted in…
View article: Hygienic quality, adulteration of pork and histamine production by Raoultella ornithinolytica in milkfish dumpling
Hygienic quality, adulteration of pork and histamine production by Raoultella ornithinolytica in milkfish dumpling Open
Ten milkfish dumpling products purchased from retail stores in southern Taiwan were collected to determine the occurrence of biogenic amines, histamine-forming bacteria, and adulteration of pork. This study showed the high contents of aero…
View article: Are humans rational? Exploring factors influencing impulse buying intention and continuous impulse buying intention
Are humans rational? Exploring factors influencing impulse buying intention and continuous impulse buying intention Open
This study investigates the effects of consumers' impulsivity traits, option framing, product type, and cash refund promotion on consumers' online impulse buying intention. This study follows two stages to investigate factors influencing i…
View article: The Effectiveness Study of Individualized Nursing Intervention on Postoperative Rehabilitation of Patients with Gynecological Tumor
The Effectiveness Study of Individualized Nursing Intervention on Postoperative Rehabilitation of Patients with Gynecological Tumor Open
Objective: to study the effect of individualized nursing intervention on postoperative rehabilitation of patients with gynecological tumor. Methods: 80 cases of patients with gynecological tumor were rando…
View article: Analysis of the fungal community in continuous cropping cotton field of Xinjiang using 18S rDNA-PCR-DGGE
Analysis of the fungal community in continuous cropping cotton field of Xinjiang using 18S rDNA-PCR-DGGE Open
Long-term continuous cropping of cotton has caused dramatic soil-borne diseases in many places, leading to substantial agricultural losses. However, in some areas of Xingjang Uygur Autonomous Region, the obstacles caused by continuous cott…